Prof Jules Griffin, Dr M J Macleod Application Deadline: Applications accepted all year round Details This studentship aims to uncover the mechanistic basis of why fats, and in particular a subset of fats called ceramides, are independent risk factors for cardiovascular disease (CVD) by studying the lipid composition of atherosclerotic plaques – the deposits of
Prof Alexandra Johnstone, Dr Brendan Gabriel Application Deadline: 01 November 2026 Details Menopause is associated with an increased risk of cardiovascular disease (CVD) through adverse changes in lipid metabolism, adiposity, vascular function, and inflammation. Shift work, which disrupts circadian rhythms and sleep, independently elevates CVD risk through metabolic, autonomic, and behavioural pathways. The coexistence of
Dr Dawn Thompson, Dr Paolo Annibale Application Deadline: 16 November 2026 Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. G-protein coupled receptors (GPCRs) regulate almost all physiological processes and attractive targets for the pharmaceutical industry. This project will focus on how regulation of
Dr Nimesh Mody, Prof Mirela Delibegovic Application Deadline: 16 November 2026 Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. Obesity and metabolic dysfunction are associated with profound changes in immune cell function, lipid metabolism, and tissue homeostasis. Cholesterol is an essential cellular component
Dr Wael Houssen, Prof M Jaspars Application Deadline: 16 November 2026 Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. “Molecular muscles” is a term referring to molecules that can contract and stretch under a chemical signal. These compounds are very interesting and have
Dr Indrani Mukhopadhya, Dr Wael Houssen, Dr T Vogwill Application Deadline: 16 November 2026 Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. The human gut microbiota plays a fundamental role in shaping immune homeostasis, yet how strictly anaerobic commensal bacteria communicate molecular information
Prof Jules Griffin, Dr J Rochford, Prof Heather Wilson Application Deadline: 16 November 2026 Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. In obesity, adipose tissue can become inflamed with the infiltration of immune cells, particularly macrophages, which surround adipocytes to create crown-like
Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. Ageing is accompanied by profound changes in the ability of our cells to maintain protein homeostasis. In the human brain, the accumulation and mislocalisation of proteins is associated with cellular dysfunction, inflammation and neurodegeneration, yet
Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. Background Eukaryotic cells are compartmentalized by membrane structures called organelles that perform specialized functions (e.g., energy production in mitochondria and catabolic reactions in lysosomes). Organelles are structurally, and functionally, dynamic. They constantly exchange materials and
Details This fully funded, 4-year PhD project is part of a competition funded by the BBSRC EASTBIO Doctoral Training Partnership. Aggregation of TAR DNA-binding protein 43 (TDP-43) is a pathological hallmark of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer’s disease (AD), and limbic-predominant age-related TDP-43 encephalopathy (LATE). Despite its central
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