Fixed-term

About Us The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS) is one of six schools that make up the Faculty of Life Sciences & Medicine (FoLSM) at King College London. The school drives translation of world-leading basic science into advances in clinical practices with activities focusing on the Cardiac Biomedicine Department of Diabetes and Vascular Biomedicine. About The Role Applications are invited for the position of Research Assistant in the Department of Diabetes at King’s College London (KCL), working in the laboratories of Prof. Gavin Bewick. The assistant will play a central supporting role in delivering a complex, multidisciplinary research programme that investigates cilia as a novel therapeutic target in Type 1 diabetes, ensuring that day-to-day experimental work runs efficiently, reliably and to a high technical standard. The primary purpose of the role is to provide skilled laboratory support across the project, generating high-quality data in molecular biology and cell-based assays that will underpin mechanistic insights into how cilia dysfunction alters islet architecture, immune infiltration and immune cell interactions. Working closely with the Dr. Haq, the assistant will help implement and optimise protocols, maintain accurate records and sample inventories, and support the integration of datasets required to map cilia gene and protein networks in mouse and human islets. The post holder will be responsible to Dr Naila Haq as Principal Investigator and will be embedded within the Department of Diabetes at King’s College London, contributing to a collaborative team that includes academic, technical and bioinformatics staff as well as external partners at Exeter, Cardiff, UCL and international biobanks. We are looking for someone with a good undergraduate and/or Masters degree in a relevant field (e.g., cell/molecular biology, biochemistry or life/biological sciences) and a strong background in cell and molecular biology The assistant will be responsible for supporting a range of experimental approaches, including preparation and processing of mouse and human pancreatic sections for RNAScope, immunohistochemistry as well as RNA extraction and qPCR. In addition to experimental duties, the assistant will be responsible for day-to-day lab management tasks essential to project delivery, including ordering and stock control of consumables, coordinating use of shared equipment, maintaining accurate logs for reagents and antibodies, and ensuring that data are stored and backed up in line with institutional data management policies. The role holder will support the implementation of good laboratory practice, health and safety procedures and environmentally sustainable working practices, including reduction, reuse and recycling initiatives aligned with KCL and Wellcome policies. This is a full-time post (35 hours per week), and you will be offered a  fixed term contract for 24 months. About You To be successful in this role, we are looking for candidates to have the following skills and experience: Essential criteria Good undergraduate and/or Master’s degree in a relevant field (e.g. cell/molecular biology, or life/biological sciences). Strong background in Cell/Molecular biology. Reliable, motivated and hard-working. Able to plan and prioritise workload and keep clear and well-organised laboratory notes and records. Good communication and writing skills. Desirable criteria Proven experience of working in a scientific laboratory. Research experience in related field (e.g setting up cellular, molecular and/or biochemical assays, cell imaging etc). Pancreatic islet isolation from murine models Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process. Further Information At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university. The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension. We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination. When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance. We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible. We reserve the right to close adverts early due to the volume of applications we receive. While the closing date may change, all adverts will close at 23:59 to allow sufficient time for applications to be submitted on that day. We encourage you to apply at the earliest opportunity to avoid disappointment as once we have closed a vacancy you will be unable to submit your application.

About us: Dr Teodora Trendafilova is supported by a Wellcome Early Career Fellowship. Her research aims to improve our understanding of the neurobiology of arthritis pain, focusing on the dynamic changes that occur over the course of the disease. In particular, her work investigates how the spinal cord and its interactions with the dorsal root ganglia evolve during chronic inflammation and contribute to persistent pain. Teodora is sponsored by Dr Franziska Denk at the Wolfson Sensory, Pain and Regeneration Centre. As a successful candidate you would receive day-to-day guidance from Teodora. You would also benefit from the expertise and collaborative environment of Dr Denk’s established research group, who study peripheral neuro-immune-stromal cell interactions in chronic pain conditions. Within our teams, you would therefore have the opportunity to learn more about a wide variety of techniques relevant to pain research, as well as become a member of the Wolfson SPaRC – a world-leading translational science centre focused on neurological and sensory disorders. About the role: We are looking for somebody who has experience with the techniques required for this post, including stereotaxic injections, chemogenetics, histology and molecular biology. Some surgical experience is essential. Training will be provided in in vivo calcium imaging using our multiphoton imaging setup. The role also includes developing a novel approach for awake imaging, which may involve 8 weeks of training in the US. If you fulfil our essential criteria and are a dedicated researcher with enthusiasm for high-quality science, teamwork, and effective organisational skills, you will be a great fit for this position. Your funding will come from the Wellcome Trust and includes financial support for attending career development courses and an annual conference. A relocation allowance is also available for candidates moving from outside London. This is a full-time post (35 hours per week), and you will be offered a fixed term contract for 3 years. Ideal start date is 1st September 2026. Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information. About you: To be successful in this role, we are looking for candidates to have the following skills and experience: Essential criteria PhD qualified in relevant subject area (Neuroscience, Pharmacology, Biomedical Sciences) or PhD near completion. Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. Should the successful candidate be awaiting the award of their PhD, the appointment will be made at Grade 5, spinal point 30 with the title of Research Assistant until confirmation of the award of the PhD has been received. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6, spine point 31. Experience with rodent surgery, preferably including stereotaxic injections. Proven ability to work as part of a team Ability to work independently, effectively planning and organizing one’s own time and workload Proven scientific writing and speaking skills Evidence of good problem-solving skills Desirable criteria Experience with in vivo recordings in rodents and computational analysis in the context of Ca2+ imaging Knowledge of the pain or arthritis fields Experience with rodent behaviour experiments Ability and willingness to travel for a collaborative visit of 8 weeks to the US Home Office Personal License PIL A-C Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process. * Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6. Further Information At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university. The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension. We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination. When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance. We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible. We reserve the right to close adverts early due to the volume of applications we receive. While the closing date may change, all adverts will close at 23:59 to allow sufficient time for applications to be submitted on that day. We encourage you to apply at the earliest opportunity to avoid

About Us The successful candidate will join our new MSCA Doctoral Network: VISIONBRAIN – Cutting-edge Human In Vitro And In Silico Biomedical Tools On Brain Disorders. This EU-funded project will train 15 early-stage researchers to develop human-relevant neuroscience tools beyond animal models, advancing next-generation in vitro and in silico New Approach Methodologies for complex brain disorders. We will host the successful candidate at the Department of Forensic and Neurodevelopmental Sciences (FANS), Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King’s College London. The IoPPN aims to change and shape how we understand, prevent and treat mental health and other conditions that affect the brain. We work to transform care for people who are affected by mental health and neurological conditions, through world-class research, education and training, to serve communities locally and globally. About the role We are looking for a talented and motivated candidate to join us as a Marie Skłodowska-Curie Actions (MSCA) Doctoral Candidate (fixed-term 3 years, 100%FTE) to develop computational models of the neonatal brain. The successful candidate will work on the intersection of neuroscience and new computational methods, combining mathematical and biophysical models with state-of-the-art diffusion and functional MRI data, in typically and atypically developing populations through the lifespan. Note: The applicant must not have resided or carried out their main activity (work/studies) in the United Kingdom for more than 12 months in the 36 months immediately before the recruitment date, and must not already hold a PhD/doctoral degree. About the project: Using Magnetic resonance imaging (MRI) we are able to assess how brain regions are connected (structural connectivity) and communicate (functional connectivity). In this project we will use mathematical descriptions of neuronal spontaneous activity and network theory, to produce biologically plausible computational models of connectivity in the newborn brain, using state-of-the-art multimodal neonatal and adult MRI data. Computational models allow the inference of whole-brain neuronal dynamic characteristics underlying the association between local functional dynamics and structural connections. Such models help us integrate structural and functional networks, providing information not accessible using single modalities. Importantly, this approach needs to be reconsidered and adapted for the developing brain. To do so, we will use high-quality MRI data in a large cohort of infants (N~1000), including subgroups with clinical conditions. Our approach has the potential to deliver fundamental new insights into developing connectivity in typically and atypically developing individuals, improving our understanding of neurodevelopmental conditions such as autism and attention deficit hyperactivity disorder. The role involves working collaboratively with a range of stakeholders, including academic and industry partners across Europe. This position is suited for an enthusiastic, curious and self-motivated individual willing to become a leader in the emerging field of computational neuroscience, i.e. embracing both computational/mathematical methods and applied neuroscience. This is a full-time post, and you will be offered a fixed-term contract for 36 months. You will complete a PhD thesis, undertake mandatory secondments (3–6 months) with partner institutions, and participate in network-wide training events. Applicants must meet all MSCA DN eligibility criteria at the time of recruitment: Doctoral Status Rule: The applicant must not already hold a PhD/doctoral degree. Mobility Rule: The applicant must not have resided or carried out their main activity (work/studies) in the recruitment country (United Kingdom) for more than 12 months in the 36 months immediately before the recruitment date. PhD Enrolment Requirement: The selected candidate must be eligible to enroll in the doctoral program at King’s College London. What We Offer: 36-month MSCA employment contract MSCA allowances package (living + mobility; family allowance if applicable), in accordance with MSCA programme rules Comprehensive international training programme through the Doctoral Network (including courses, summer schools, and transferable skills training) Secondments with consortium partners Joint supervision and access to a multi-stakeholder ecosystem Full details and official call documentation:  https://marie-sklodowska-curie-actions.ec.europa.eu/actions/doctoral-networks Direct link to the project:  https://cordis.europa.eu/project/id/101227124 Applications must be submitted by the PhD route (you can apply through HR too if you decide to submit both applications, but we need all candidates registered through King’s Apply): https://apply.kcl.ac.uk  About You Essential criteria Upper second-class bachelor’s degree (or higher) in psychology, neuroscience, biomedical sciences, mathematics, physics, engineering, or a related discipline Excellent interpersonal and communication skills. Highly organised with attention to detail Experience with research methods in neuroscience and neuroimaging (diffusion/functional MRI and/or EEG) Competency in statistics and programming (e.g., Python, R, MATLAB) Strong interest in both neuroscience and computational methods Desirable criteria Strong interest in neurodevelopment and/or neurodevelopmental conditions Previous research publications or conference presentations (either as first-author or as a co-author) Machine learning and/or computational modelling experience Experience with brain network modelling and analysis Experience processing diffusion and/or functional MRI data Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process. Further Information At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university. The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension. We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination. When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance. We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the

About the role As a Medical Research Council-funded Postdoctoral Research Associate you will spearhead an innovative investigation into the transcription factor ERG to determine its role as a master regulator of lymphatic identity and immune response. Working at a world-leading institution within a high-impact collaborative environment, you will employ in vivo models with state-of-the-art molecular and cellular assays to uncover how ERG functions as an “immune gatekeeper” during both steady-state and inflammatory challenges. Ultimately, your findings will define a new roadmap for therapeutic targets to treat debilitating conditions like primary lymphoedema, directly bridging the gap between fundamental molecular science and patient benefit. What you would be doing In this role, you will lead investigations into how the transcription factor ERG regulates lymphatic identity and immune cell trafficking. Your responsibilities will include performing in vivo functional assays to quantify lymphatic drainage and immune cell trafficking. You will utilize single-cell transcriptomics and high-resolution multiplexed imaging to map cellular landscapes in mouse and human tissues. Additionally, you will conduct mechanistic studies to identify the role of ERG in lymph node maintenance. Throughout, you will develop advanced analytical skills and benefit from a dynamic and collaborative research environment.   What we are looking for We are looking for an ambitious and highly motivated postdoctoral researcher with a PhD in vascular biology, immunology, or cell biology to join this collaborative project. While a full person specification is available in the job description, we are specifically looking for candidates who can demonstrate: *Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £43,863 – £47,223 per annum. Expertise in advanced in vivo techniques using genetically modified mice, such as functional lymphatic assays and immune cell trafficking models. Proficiency in high-resolution imaging, specifically spatially-resolved multiplexed imaging and whole-mount tissue analysis using confocal microscopy. Experience with single-cell transcriptomics (scRNA-seq), including the ability to design experiments using 10x Genomics and perform downstream computational data analysis. Technical skills in molecular biology and in vitro assays, such as CRISPR or siRNA-mediated gene inhibition and functional studies of endothelial barrier integrity and leukocyte adhesion. Strong analytical and computational abilities to interpret high-dimensional datasets, identify unique gene signatures, and predict cellular interactions. A collaborative and proactive mindset, with the ability to share expertise across different lab environments and a commitment to preparing high-quality manuscripts for publication. The ambition to develop an independent research role, demonstrating the drive to prepare for future independent academic positions through the acquisition of new skills and ideas. What we can offer you By joining this project, you will benefit from a wealth of professional and scientific opportunities designed to launch your career as an independent investigator: A high-impact collaborative environment. You will work across a unique partnership between Imperial College London and the University of Nottingham, directly sharing expertise with project leads specializing in ERG transcriptional regulation (Dr Graeme Birdsey, Imperial College London) and immune response/lymph node trafficking (Prof. Jacqui Shields, University of Nottingham). Access to cutting-edge technology. You will be trained on and have full access to state-of-the-art platforms, including the 10x genomics platform for single-cell transcriptomics and systems for advanced, spatially-resolved multiplexed imaging. Translational research impact. You will contribute to a project with significant clinical relevance, collaborating with experts at City St. George’s, University of London, to identify therapeutic targets for debilitating conditions like primary lymphoedema. Scientific recognition and dissemination. You will be responsible for reporting your findings in high-quality manuscripts and presenting your work at national and international conferences, ensuring your contributions are recognized by the global scientific community. Sector-leading salary and remuneration package (including 39 days off a year). Structured career development. This 36-month post is designed to support you in developing independent research ideas to prepare you for future senior academic positions. Further information This is a Full time fixed-term, fixed -term ( 3 years) role based at our White City Campus. If you require any further details on the role please contact: Dr Graeme Birdsey (g.birdsey@imperial.ac.uk). Lab webpage: https://profiles.imperial.ac.uk/g.birdsey Apply Now

We have a fantastic doctoral training opportunity in human immunology, multiomics approaches, and computational biology, due to start in October 2026. Funding for this project covers stipend and fees for students with a home fee status only. The small intestine is the largest epithelial surface in contact with the external environment, and is not only the key site of nutrient absorption and endocrine function, but a highly active immune organ which shapes immune responses throughout the body. The effect of age, disease, and the exposome on small intestinal absorbative, metabolic, and immune function has not been well-studied. Little is understood about how the broad and complex functions of the small intestine, including digestion and the  expression/activity of digestive enzymes produced by the brush border membrane, alter, either during the human lifespan, with a range of environmental factors, or in human disease. This project seeks to understand how human small intestinal function changes with age. We hypothesise that there are broad changes in digestive, absorptive, metabolic, and immunological pathways in the small intestine which occur during growth, development and aging in healthy human subjects. The Gut Chronicle project will generate a richly annotated, integrated multi-omic (bulk, single-cell and spatial transcriptomics, proteomics and epigenetics) chronicle of the small intestinal epithelium across the lifespan. This DPhil project will establish a foundation for understanding age-associated variation in intestinal function and its relevance to health, disorders, and disease. The DPhil student will work at the interface of computational biology, gastroenterology and molecular medicine, using state-of-the-art transcriptomic, proteomic and epigenomic profiling techniques to map how intestinal epithelial and immune functions evolve across the human lifespan. This project offers an exceptional opportunity to integrate advanced bioinformatics, wet-lab and translational research within a multidisciplinary academic-industry environment. The student will gain experience in both experimental and computational methods, contributing to foundational datasets that will inform future studies on intestinal health, aging and enteropathies. This project will be supported by Dr Mourabit from AMYRA biosciences. The successful candidate will have the opportunity to join the Enteropathy Consortium, which brings together other AMYRA-funded/co-funded international PhD students to support innovation and collaboration. There may be opportunities to collaborate and travel to Switzerland or Finland as part of the consortium. Interested candidates should contact the supervisors for an informal discussion (michael.fitzpatrick@ndm.ox.ac.uk and agne.antanaviciute@rdm.ox.ac.uk). Further information about the groups’ research can be found here: https://www.rdm.ox.ac.uk/research/antanaviciute-group-computational-biology-and-tissue-immunology https://www.expmedndm.ox.ac.uk/tgu/research/oxford-coeliac-network https://www.expmedndm.ox.ac.uk/team/michael-fitzpatrick TRAINING OPPORTUNITIES Students will have access to a wide variety of training and courses within Oxford University teaching and training schemes. As part of this project, the student will split their time between the groups of Dr. Michael FitzPatrick and Dr. Agne Antanaviciute due to interdisciplinary nature of the work. As such, the successful applicant will have access to training in the following techniques: NGS data analysis, single cell and bulk multi-omics, including scRNA-Seq, CITE-Seq, scATAC-Seq, TCR/BCR repertoire analysis, spatial ‘omics and imaging, intestinal organoids, statistical inference and machine learning. The interdisciplinary nature of this project means students will interact with and learn from experts in both wet- and dry-lab research, gaining experience in experimental design, data generation and computational data integration and modelling. In addition, opportunities will be provided for attendance at national and international workshops and conferences, as well as regularly interface with industry collaborators at AMYRA, and the opportunity to visit and collaborate with other labs within the Enteropathy Consortium. Students will be enrolled on the MRC Weatherall Institute of Molecular Medicine DPhil Course, which takes place in the autumn of their first year. Running over several days, this course helps students to develop basic research and presentation skills, as well as introducing them to a wide range of scientific techniques and principles, ensuring that students have the opportunity to build a broad-based understanding of differing research methodologies. Generic skills training is offered through the Medical Sciences Division’s Skills Training Programme. This programme offers a comprehensive range of courses covering many important areas of researcher development: knowledge and intellectual abilities, personal effectiveness, research governance and organisation, and engagement, influence, and impact. Students are actively encouraged to take advantage of the training opportunities available to them. As well as the specific training detailed above, students will have access to a wide range of seminars and training opportunities through the many research institutes and centres based in Oxford. The Department has a successful mentoring scheme, open to graduate students, which provides an additional possible channel for personal and professional development outside the regular supervisory framework. We hold an Athena SWAN Silver Award in recognition of our efforts to build a happy and rewarding environment where all staff and students are supported to achieve their full potential. ADDITIONAL SUPERVISORS 1 Dr. Michael FitzPatrick, Nuffield Department of Medicine (second PI) 2 Dr. Sulayman Mourabit, AMYRA (Industry Supervisor)