Fixed-term

Do you want to contribute to top quality research? In our research group, you will find a unique opportunity to work within an ERC funded project together with top researchers in the intersection between neuroscience, psychology, and chemistry to jointly try to understand how the human sense of smell works. To achieve this goal, we conduct various research projects that try to link odor perception to brain processing using several different methods, including electrophysiological (EEG), functional and structural brain imaging, as well as behavior and psychophysical measurements. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at the highest international level. Your mission We are seeking a postdoctoral researcher to lead a work package in our ERC Synergy grant (D2Smell) with the overall aim to digitalize smell. The aim of this sub-project is to develop and validate a new method to record electrophysiological responses to odor stimuli directly from the human olfactory receptors. Your main tasks will be, with the help of research assistants, to develop the recording setup, design and conduct experiments, analyze collected data, and publish the results in scientific articles. This will be done in direct collaboration with materials scientists in another ERC project with the goal of developing new electrodes. You will also work in close collaboration with other nodes within the ERC project. Beyond working on the ERC project, you will also be able to pursue your own research questions within the framework of our general research program. As a postdoctoral researcher in the group, you get the opportunity to work in a successful and well-funded research group with a number of senior and junior researchers. Our research group collaborates with a number of prominent research groups around the world, which provides an opportunity for international exchanges. Your profile To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier. The successful candidate must have a PhD in a relevant research field as well as previous well-documented research experience of working with electrophysiological measurements and analyses. It is desirable if you have experience with single cell or intracranial electrophysiological recordings, prior publications using electrophysiological recordings, advanced analysis skills, or previous experience with assessing behavioral and neural processing of olfactory or other sensory stimuli. It is considered a merit if the successful candidate can demonstrate publications in international peer-reviewed journals. English is the main language of communication in the research group, therefore, strong written and spoken English skills are necessary. Knowledge of Swedish is beneficial. Potential candidates will be interviewed, and personal skills and qualities will be considered when filling the position. Importance will be placed on independence, social skills and the ability to work within a multinational and transdisciplinary environment. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Location: Solna Application An employment application must contain the following documents in English or Swedish: PhD certificate A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page) The application is to be submitted through the Varbi recruitment system. Apply Now

Do you want to contribute to improving human health? Come and join us at the Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm. In the research group led by Laura Baranello, we are particularly interested in the molecular mechanisms defining the crosstalk between transcription, DNA topology and chromatin folding, with the aim to design improved strategies for anti-cancer treatment. We are a young and dynamic research team with a well-established collaborative network. Our lab is located at Biomedicum, a top modern research building with a large repertoire of researchers and access to state-of-the-art infrastructure and facilities. Your mission The Baranello Lab – Drawing from our expertise in the fields of topoisomerase and cancer biology, we aim to answer fundamental questions about how transcription, replication and DNA topology are functionally coordinated in human cells. We use state-of-the-art approaches to assess transcriptomic, epigenomic and replisomic profiles, as well as molecular biology, advanced microscopy and drug screens to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello et al. Cell 2016; Wiegard et al. Molecular Cell 2021; Das et al. Molecular Cell 2022; Cameron et al. Science Advances 2023). The overall aim is to reveal novel cancer therapy targets and improved strategies for personalized treatment. Recently we have identified a protein complex called “topoisome” in which the oncoprotein MYC recruits and increases the catalytic activities of both Topoisomerase 1 and 2 to promote high rates of transcription (Das et al. Molecular Cell 2022). The successful candidate will play a leading role in a research project, focused to address the functional role of the topoisome during transcription. Specifically we want to study the coordination of the topoisome and the transcriptional machinery. The outcome of this work is predicted to inspire a new strategy to target MYC in cancer, which will be tested in MYC-driven cancer models. This multidisciplinary project involves microscopy, biochemistry  and molecular biology. The research assistant will plan and execute experiments, analyze data, interpret, and present the results, initially under supervision but with greater independence going forward. Your profile We are looking for a highly motivated, driven, enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidate should have a strong collaborative approach to research, be a team player as capable of working independently and contribute to a good social environment in the laboratory. Requirements: Master’s degree in Biomedicine or similar Expertise in transcription regulation and DNA topology Expertise in molecular biology Expertise in microscopy Interest in solving intricate scientific questions and willingness to help PhD/master students. Excellent interpersonal and communication skills (in English written and verbal). Emphasis will be also placed on personal suitability, fitting well into the current research group. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Our lab is eager to provide the candidate with an opportunity to develop and/or apply state-of-the-art methodologies to solve timely biological key questions Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Solna Visit Baranello Lab: https://ki.se/en/research/groups/topoisomerases-chromatin-biology-and-cancer-laura-baranellos-group Application The application is to be submitted through the Varbi recruitment system. A complete curriculum vitae (max 3 pages) with publication list A letter describing previous accomplishments, technical expertise and why you want to work with us (no more than one-page, generic letters not accepted) Names and contact details of one scientist for reference letter Apply Now

Do you want to contribute to top quality medical research? The Department of Laboratory Medicine consists of seven divisions in which both research and teaching are conducted. The department is involved in advanced research in both basic and applied research. The Division of Biomolecular and Cellular Medicine focuses on the use of modified biomolecules, cells and cell products as novel therapeutic agents and the identification and study of suitable biomolecular and cellular targets for therapy and diagnosis. Currently, Assistant Professor Joel Nordin’s research group is looking for a research assistant. Your mission As a research assistant, you will work on the development of new therapies for prostate cancer.  Most of the research will be conducted using cell lines.  The overall goal is to develop protein conjugates and cell-based therapies for prostate cancer. In this project, lipid nanoparticles (LNPs) will be used as delivery systems to engineer immune cells. Lipid nanoparticles are being explored as delivery tools for in vivo engineering due to their abilities to carry nucleic acids and enable targeted delivery. Protein conjugates can be used for the specific targeting and delivery of functional groups such as oligonucleotides. Current cell-based therapies are limited by the need to manipulate with ex vivo, production times and costs. New therapies offering a targeted approach at different levels (protein and RNA) could offer significant advantages in prostate cancer therapies. Your profile The applicant should have a solid background in cellular biology. The position requires practical experience in the following areas: cloning, lentivirus production, transduction, mammalian cell culture, primary T cell isolation, and flow cytometry. It is considered an advantage if the applicant has experience in the field of extracellular vesicles and cell-based immunotherapies. Additional consideration will be given to candidates with a medical background. Further experience in isolation and characterization of extracellular vesicles will also be of merit. Excellent proficiency in both spoken and written English is important. We are looking for an energetic and passionate person who fits in and actively contributes to our team. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Flemingsberg Application The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. Apply Now

Do you want to contribute to top-quality medical research? Being a doctoral student means being admitted to a postgraduate education (doctoral training) where one follows an individual study plan. A doctoral student engages in a research project under supervision, supplemented by courses and other learning activities. A doctoral degree requires the equivalent of four years of full-time postgraduate education. Research group The research group is led by Professor Liv Eidsmo and conducts translational research in dermatology in close collaboration with Karolinska University Hospital. The focus is on immunological memory and T-cell-driven inflammation in the skin, including inflammatory skin diseases and immune-related side effects of modern cancer treatment. The group works primarily with human tissue samples and advanced cellular and molecular analysis methods in an international research environment. The doctoral project and the doctoral student’s tasks The project aims to map mechanisms behind T-cell-driven skin inflammation that develops during immune-activating cancer treatment. The doctoral student is expected to actively participate in the entire research chain, from hypothesis formulation and experimental design to analysis, interpretation and publication of results, as well as the joint safety and administrative work required to carry out the project. The work includes laboratory-based studies on human samples, including flow cytometry, single cell sequencing of RNA, visualization techniques such as confocal microscopy and spatial transcriptomics, and functional analyses of primary cells, including synthetic biology in collaboration with co-supervisor Wermeling. In collaboration with co-supervisor Parlak, the doctoral student will be involved in the development and testing of biosensors. The work takes place at the Center for Molecular Medicine at Karolinska Hospital and part of the doctoral student service is to actively participate in mandatory courses, seminars, journal clubs and national and international scientific meetings. What do we offer? A creative, international and inspiring environment filled with competence and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Here we conduct successful medical research and have the largest range of medical education in Sweden. At KI you will meet researchers with different research areas working together. It is this cross-border collaboration that contributes to KI’s world-leading position in research. As a doctoral student, you are offered an individual research project, a well-trained supervisor, a wide range of elective courses and the opportunity to work in a successful research group. Karolinska Institutet has collaborations with prominent universities all over the world, which provides opportunities for international exchanges. As an employed doctoral student, you receive a contractual salary, you are allowed to exercise freely in our modern health care facilities and you are reimbursed for medical care. Eligibility requirements for doctoral education To participate in the selection for a doctoral position, you must prove both the basic (A) and the specific (B) eligibility requirements before the application period closes. It is your responsibility as an applicant to prove your eligibility by following the instructions on the Eligibility for Doctoral Education webpage. A) Basic eligibility requirements You meet the basic eligibility requirements for doctoral education if you: have completed an advanced level degree (Master’s or Doctoral degree), or have completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits are at advanced level, or has otherwise acquired essentially equivalent knowledge.* Follow the instructions on the Eligibility for doctoral education webpage . *If you consider yourself to have equivalent knowledge, you should follow the instructions on the website Assessment of equivalent knowledge for basic eligibility for doctoral education. B) Special eligibility requirements You meet the specific eligibility requirements for doctoral education if you: – Certifies knowledge of English (equivalent to English B/English 6 at high school with a passing grade). Follow the instructions on the English language requirements for doctoral education website. Document verification Karolinska Institutet checks documents to detect forgeries. Karolinska Institutet reserves the right to revoke admission decisions if forgeries or irregularities are detected. Submission of false documents is a violation of Swedish law and is considered grounds for legal action. Skills and personal qualities Claim Advanced level degree in biomedicine, biotechnology, molecular biology, immunology, medicine or equivalent. Documented experience of experimental laboratory work. Experience in flow cytometry, visualization techniques and working with primary human tissue cells. Good ability to communicate scientifically, both orally and in writing, in English. Good knowledge of Swedish, both spoken and written. Meritorious Experience working with human tissue samples (e.g. skin biopsies). Cell sorting and more advanced flow cytometry. RNA-based analyses, single-cell or spatial omics methods. Experience working with primary T cells, fibroblasts or keratinocytes. Experience with structured laboratory work and documentation (e.g. ELN). Engineering degree Personal qualities We are looking for a meticulous, analytical and structured person with good collaboration skills and a professional approach to quality, documentation and common working methods in the research environment. Terms The doctoral position involves employment as a doctoral student for a maximum of 4 years full-time. Application You apply for the doctoral position in the recruitment tool Varbi. Use the button at the top right and follow the instructions. We prefer that your application is written in English, but it is also possible to apply in Swedish. Your application should include these documents: – A personal letter and curriculum vitae – Any degree theses and publications – Other documents that prove the skills and qualities requested above – Documents that prove the basic eligibility requirement (see A above) – Documents that prove the specific eligibility requirement (see B above) Selection Selection among eligible applicants will be made based on their ability to benefit from postgraduate education. An overall assessment of the applicants’ qualifications and suitability will be made. The following assessment criteria are applied at Karolinska Institutet: – Documented subject knowledge of importance to the research area – Analytical skills – Other documented knowledge/experience that may be of importance to the current doctoral education All applicants will receive information when the recruitment is completed. Apply Now

Do you want to contribute to top quality medical research? Your mission The mission of the hired research assistant will be to conduct wet lab research in a new project focused on establishing a new immunomodulatory strategy to boost brain immunity against bacterial infections causing meningoencephalitis. The laboratory of Associate Professor Federico Iovino investigates pathogenesis of bacterial meningitis and encephalitis with the ultimate goal of developing new therapeutic approaches to reinforce immune responses and prevent permanent brain damage. Your profile The ideal candidate should possess a bachelor or master degree in biological sciences (or related fields) and certified expertise in molecular biology techniques (ELISA, western blot, advanced microscopy, flow cytometry) as well in microbiology (preferably bacteriology) and neurobiology. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Solna Application The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. This is a special fixed-term position for 6 months. Apply Now

Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required. The research group Elisabeth Nyström´s group at the Division of Immunology and Respiratory Medicine is an interdisciplinary research team investigating how epithelial tissues build and regulate protective barriers. We focus on how intestinal mucus and mucus-producing goblet cells create a dynamic interface between the host and its environment, shaping microbial interactions, molecular exchange, and immune activation. By integrating molecular biology, biochemistry, and physiology, we aim to uncover how mucus is assembled and functions in health and disease. The group is embedded in a collaborative and interdisciplinary environment, with close interactions across immunology, bioinformatics, structural biology, biochemistry, and clinical research, both locally, nationally and internationally. The doctoral student project and the duties of the doctoral student The project will investigate how diverse mucus-producing cell populations shape mucus properties, and how changes in their composition influence mucus function through the regulation of post-translational modifications of mucus proteins. Intestinal infection models will be used as systems in which goblet cell composition and mucus function are altered. The doctoral student will use single-cell RNA sequencing (scRNA-seq) approaches to characterize goblet cell populations, combined with ex vivo mucus analysis platforms to link cellular composition to function. In addition, the student will apply mass spectrometry-based approaches to study post-translational modifications and validate findings using biochemical analyses. The project includes experimental work in animal models, and the doctoral student will be responsible for performing infection experiments, including handling and propagation of relevant bacterial or parasitic organisms, as well as monitoring disease progression. Some of these activities may require flexibility in working hours, including work outside standard hours or during weekends. The doctoral student is expected to drive their project forward with increasing independence, while actively engaging with the research group. Collaboration within the team and contribution to the overall lab environment are important parts of the role. What do we offer? A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care. Eligibility requirements for doctoral education In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline. It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education. A) General eligibility requirement You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you: have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or have acquired substantially equivalent knowledge in some other way in Sweden or abroad.* Follow the instructions on the web page Entry requirements (eligibility) for doctoral education. *If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education. B) Specific eligibility requirement You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you: – Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school. Follow the instructions on the web page English language requirements for doctoral education. Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action. (A) and (B) can only be certified by the documentation requirement for doctoral education. Skills and personal qualities Required qualifications A Master’s degree in molecular biology, biochemistry, cell biology, biomedical sciences, or a closely related discipline with a strong experimental component Documented experience in experimental laboratory work in relevant areas such as cell biology, microbiology, or molecular biology Certification for mouse handling and documented experience working with animals Strong written and oral communication skills in English Meritorious Experience with intestinal infection models or microbiology (bacterial or parasitic) Experience with single-cell RNA sequencing or other transcriptomic approaches including sample preparation and data analysis Basic bioinformatics skills (e.g., R or Python) and experience with handling large datasets Experience with proteomics, mass spectrometry, or analysis of post-translational modifications Experience with advanced imaging techniques, preferably confocal microscopy or other 3D imaging approaches Ex vivo tissue assays including tissue harvest and dissection, preferably intestinal. We attach great importance to personal qualities in this recruitment. As a person, you are: Analytical, structured, and detail-oriented, with a strong commitment to high-quality work and an interest in solving complex research questions. Self-driven and able to work independently, with the ability to take initiative and move projects forward while seeking input and raising challenges constructively when needed. Curious and motivated to learn new methods, skills, and concepts, with the perseverance and resilience to see projects through to completion. Collaborative, with good communication skills, and comfortable working in interdisciplinary teams with diverse backgrounds. Willing to contribute to a positive and well-functioning lab environment. Terms and conditions The doctoral student will be employed on a doctoral studentship maximum 4 years full-time. Application process Submit your application and supporting documents through the Varbi recruitment system.

Do you want to contribute to top-quality medical research? The Laboratory of Systems Virology at Karolinska Institutet is at the forefront of understanding how viruses interact with the human host at the systems level. By integrating groundbreaking multiomic methods at the single-cell level with advanced experimental models, such as human organoids, the laboratory maps the molecular and cellular mechanisms that govern viral pathogenesis, immune evasion and disease progression. Our research spans a broad spectrum of clinically relevant viruses, with a particular focus on retroviruses (e.g. HIV, HTLV) and arboviruses (e.g. dengue, zika), where we investigate how host-virus dynamics affect outcomes in different tissues. By combining computational systems biology with rigorous experimental virology, we transform complex biological data into mechanistic insights with direct relevance for therapeutic and diagnostic innovation. The laboratory is based at one of the world’s leading medical universities and promotes an international, collaborative and intellectually ambitious environment where early-career researchers are given the opportunity to develop as independent researchers and contribute to science that makes a difference. The current project is part of the EU’s Horizon project COMBAT and other projects supported by the Swedish Research Council. Your role As a postdoctoral fellow in the Systems Virology Laboratory, your mission is to advance the frontiers of viral pathogenesis research using state-of-the-art human organoid models. You will have overall responsibility for the generation, maintenance, and differentiation of brain, gut, and placenta organoids, as well as optimizing robust protocols that form the experimental foundation of the laboratory’s research program. Who are you? To be employed as a postdoctoral researcher, you must have completed a doctoral degree or a foreign degree that is considered equivalent to a Swedish doctoral degree. This eligibility requirement must be met no later than the time the employment decision is made. It is an advantage if you have completed your doctoral degree within the last three years; if there are special reasons, your degree may have been completed earlier. The ideal candidate for the position has a PhD in virology, cell biology, developmental biology, neuroscience or a closely related biomedical field, with a solid practical background in 3D cell culture systems such as organoids or spheroids. Direct experience in generating, maintaining and differentiating at least one of the relevant organoid types – brain, intestine or placenta – is required, preferably combined with familiarity with iPSC culture and differentiation protocols. You should be proficient in confocal and fluorescence microscopy, standard molecular biology techniques, and immunofluorescence on 3D tissue sections; experience in single-cell RNA sequencing or CRISPR would further strengthen the application. In addition to technical skills, the role requires someone who is highly independent, responsible, and able to optimize and debug complex protocols with minimal supervision, as the organoid systems will serve as the experimental backbone of the entire research program. The ability to train junior lab members, contribute to scientific writing, and collaborate effectively within a multidisciplinary team is equally important. You are likely to have a PhD in brain or gut organoid models with some experience in infection biology, or established virologists who have worked extensively with complex 3D tissue models, supported by a publication list that reflects expertise in one or both of these areas. What do we offer? A creative, international, inspiring environment filled with expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Here we conduct successful medical research and have the largest range of medical education in Sweden. At KI you will meet researchers with different research areas working together. It is this cross-border collaboration that contributes to KI’s world-leading position in research. Several of the people you meet in healthcare are educated at KI. A close relationship with the healthcare sector is important for creating education and research of the highest quality. As a university, Karolinska Institutet is also a government agency. This means that as an employee you receive good benefits through our collective agreement. The Systems Virology Laboratory offers a unique interdisciplinary educational environment where a postdoctoral fellow can develop a hybrid scientific identity spanning both practical laboratory experiments and data-driven, quantitative analysis. The laboratory integrates large-scale methods such as transcriptomics, proteomics, metabolomics, and network biology to understand how viruses reshape host cell systems on a global scale. This means that as a postdoctoral fellow you will have access to cutting-edge multi-omics techniques and, increasingly, to computational tools and bioinformatics pipelines that are highly valued in both academia and industry. The work with human organoids adds an additional dimension of translational relevance, as the results are directly applicable to understanding human diseases rather than being limited to animal models or simplified cell lines. The combination of complex tissue modeling and systems-level analysis places you at the forefront of infection biology, making your profile competitive for independent research positions, grants and collaborations. In addition to technical training, a systems virology environment tends to foster a culture of integrated thinking, where you learn to link molecular mechanisms to tissue and organismal outcomes, a skill that is becoming increasingly rare and sought after. The current position offers the chance to build a scientifically distinct profile at the intersection of virology, stem cell biology and systems biology, opening doors far beyond the traditional career path in virology. Location: Flemingsberg Read about the systems virology lab (eng) Application The application must consist of the following documents, written in English or Swedish: Proof of doctoral degree A complete CV including date of public defense, title of thesis, previous academic positions, academic title, current position, academic awards and committee work A complete list of publications A summary of current work (maximum one page) Applications must be made via the Varbi recruitment system. Apply Now

Do you want to contribute to improving human health?  We are seeking a highly motivated and innovative scientist with expertise in neuroimmunology and glial biology research, with a particular focus on microglial regulation of myelin and neurons in aging and neurological disorders. The position is embedded in a strong translational environment within the Division of Neuro, Department of Clinical Neuroscience, and will address key challenges in diseases such as multiple sclerosis (MS), neuroinflammatory conditions, and age-related neurological decline. The research is expected to integrate mechanistic insights with clinical relevance and translational value, contributing to an improved understanding and treatment of central nervous system CNS disorders. Your mission  In collaboration with research teams within the department and beyond, and by combining advanced experimental approaches, novel transgenic tools, and access to patient-derived materials, you will: Establish an independent, internationally competitive research program, and secure external funding Carry out new and ongoing research to: (i) Elucidate the fundamental mechanisms governing myelin vulnerability and repair across aging and neurological diseases, with a particular focus on microglia-myelin interactions and region-specific CNS resilience. (ii) Develop innovative translational approaches targeting neuroinflammation and remyelination. Supervise doctoral students and postdoctoral researchers, and contribute to teaching in neuroimmunology-related PhD courses. The employment as Assistant Professor is time limited for 6 years with the right to apply for promotion to Senior Lecturer. Eligibility requirements  Those eligible for employment as an Assistant Professor are individuals who have been awarded a PhD or attained equivalent research competence. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than seven years, normally, prior to the expiry of the application period for the position as assistant professor. Those who have been awarded a PhD or attained equivalent research competence earlier may however be considered if special grounds exist. Special grounds refer to: parental leave, positions of trust in trade union organizations mandatory service in the total defense forces long-term illness Ground, dates and extent must be clearly specified in the application and verified with relevant documentation. Appointment to the position of Assistant Professor requires good scientific skills and good pedagogical skills. (See the Instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet). It is a requirement that you have completed three weeks of courses on teaching in higher education as indicated in the recommendations of the Association of Swedish Higher Education Institution. If you lack such education at the time of employment, you must undergo such education during the first two years of employment. Bases of assessment  Demonstrated scientific expertise in experimental neuroimmunology, microglial biology, or related relevant fields. Particular emphasis will be placed on a strong track record of scientific excellence, including high productivity, translational relevance, independence, and international engagement. For employment as Assistant Professor at Karolinska Institutet, the eligibility requirements and assessment criteria stated in the Instructions regarding the Appointment Procedure are applied in relation to established profile of employment. It is particilarly meritorious that you have demonstrated Scientific excellence, including quality, originality, and impact of previous research. A strong publication record in leading international journals, documented research independence, and the ability to secure competitive external funding. It is meritorious that you have demonstrated  Experience from internationally leading research environments. The ability to develop an innovative and translational research profile within neuroimmunology and clinical neuroscience, including relevance to neurological diseases such as multiple sclerosis. Teaching expertise, experience in supervision, and the ability to collaborate effectively in interdisciplinary environments. After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI. What do we offer?  A creative, international and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. Location: Solna Read more about the Department of Clinical Neuroscience Read more about the research group you will be part of Application Your application must contain a resumé and a qualifications portfolio including a description of your research plan, both presented in accordance with Karolinska Institutet’s template (http://ki.se/qualificationsportfolio). The applications will be reviewed by external reviewers, most often both national and international. For that reason, all the submitted documents should be written in English. The application is to be submitted through the Varbi recruitment system Apply Now

Do you want to contribute to top quality medical research? In our lab we combine human immunology and rodent systems to dissect the effect of genetics, metabolism and environmental factors on immune cell modulation in the context of autoimmunity. We offer a vibrant research environment, diverse expertise and a highly collaborative structure. Your mission As research assistant, your mission will be to develop CRISPR-mediated approaches to modulate T cell function in the MS animal model EAE. Daily chores will include plasmid cloning in bacteria, plasmid purification, retrovirus generation and concentration, mouse immunizations, infection of mouse T cells in vitro, adoptive transfer of cells into target animals and daily EAE scoring. Your profile You should be an independent and driven individual with a strong background in cellular and molecular biology and immunology with experience in handling mice and rats. Flow cytometry is a requisite. Experience in CNS tissue dissection and processing for downstream applications is an advantage. Good proficiency of the English language and team-working capacity are a must. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Solna Read more about the Department of Clinical Neuroscience Read more about the research group you will be part of Application The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. Apply Now