Fixed-term

PhD Position Modelling-inspired Cell Engineering for Upscaled Cultivated Meat

Job description ‘Cultivated meat’, the production of genuine meat products from in vitro culture of animal cells, is an emerging biotechnology within the field of cellular agriculture with the potential to revolutionise food production from both an environmental and ethical perspective. Unfortunately, higher eukaryotic cells in their unmodified state have severe limitations with respect to in vitro culture, presenting major challenges for the scalability of cultivated meat bioprocesses. These include slow proliferation rates, sensitivity to shear stress and a marked preference for adherent growth, amongst others. Cell engineering offers a potential solution to develop more scalable cell lines, but is held back by a limited understanding of the conditions that cells experience in large-scale cultures. We are hiring for a PhD student to join the group for a fully-funded project of 4 years to tackle this problem! Within the Flack and Haringa groups, you will develop computational tools (such as compartment models and CFD simulations) to model large-scale animal cell culture in bioreactors, and use your models to design and develop scale-down systems for cell culture that mimic the heteregenous environment cells experience at large scale. You will then engineer bovine satellite cell lines with a variety of new and improved phenotypes, relating to (for example) shear stress resistance, metabolite gradient tolerance, and metabolic efficiency, demonstrating their performance first in your scale-down systems, and later in large bioreactors. Within the scope of computational modelling and cell engineering for cultivated meat, there will be flexibility to design and direct your own research projects, and to become acquainted with new techniques and approaches. There will be opportunities to supervise MSc and BSc students in the group. Advice and discussion will be available for candidates interested in both academic and industry careers. We are a friendly, collaborative group and are looking for a highly motivated student with strong scientific communication skills. You will be joining a dynamic department with broad interests in biotechnology and synthetic biology across all domains of life. The research is funded as part of the Cellular Agriculture Netherlands Open Calls Programme, and will involve collaboration and coordination with various industrial parties and external experts. For more information, please refer to the Flack Group website and/or get in touch.  Job requirements  The ideal candidate will be an ambitious, proactive, reflective, and results-driven researcher. We are looking for the following: MSc degree in a relevant field, such as cell biology, biotechnology or a related field of biological sciences (essential). Prior lab experience in molecular biology, cloning and genetic manipulation (essential). Prior experience or strong interest in computational modelling or other dry-lab techniques (highly desirable). Prior experience with mammalian cell culture (desirable, but not essential). A strong interest in cellular agriculture/cultivated meat is essential, although specific prior experience in this area is not expected or required. Strong collaboration, communication and writing skills. TU Delft (Delft University of Technology)  Working at TU Delft means contributing to solutions that really make a difference.  For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow.  These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.  At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional.  Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.  Faculty Applied Sciences  With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor’s and specialist Master’s programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.  Click here to go to the website of the Faculty of Applied Sciences.  Conditions of employment  Doctoral candidates will be offered a 4-year period of employment in principle, but in the form of 2 employment contracts. An initial 1,5 year contract with an official go/no go progress assessment within 15 months. Followed by an additional contract for the remaining 2,5 years assuming everything goes well and performance requirements are met.  Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities, increasing from €3059 – €3881 gross per month, from the first year to the fourth year based on a fulltime contract (38 hours), plus 8% holiday allowance and an end-of-year bonus of 8.3%.   As a PhD candidate you will be enrolled in the TU Delft Graduate School. The TU Delft Graduate School provides an inspiring research environment with an excellent team of supervisors, academic staff and a mentor. The Doctoral Education Programme is aimed at developing your transferable, discipline-related and research skills.  The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.   Will you need to relocate to the Netherlands for this job? TU Delft is committed to make your move as smooth as possible! The HR unit, Coming to Delft Service, offers information on their website to help you prepare your relocation. In addition, Coming to Delft Service organises events to help you settle in the

Postdoctoral Researcher position in Cell Engineering for Cultivated Meat

Are you ready to engineer and evolve the next generation of animal cell lines for cost-effective, scalable, delicious cruelty-free meat?! Job description ‘Cultivated meat’, the production of genuine meat products from in vitro culture of animal cells, is an emerging biotechnology within the field of cellular agriculture with the potential to revolutionise food production from both an environmental and ethical perspective. Unfortunately, higher eukaryotic cells in their unmodified state have severe limitations with respect to in vitro culture, presenting major challenges for the scalability and cost-effectiveness of cultivated meat bioprocesses. These include limited cellular lifespans, slow proliferation rates, demanding medium requirements and a preference for adherent growth, amongst others. Cell engineering can solve these problems! We are hiring for multiple postdoctoral scientists to join the group for fully-funded projects of (an initial) 2 years. Within the Flack group, you will engineer and evolve bovine satellite cell lines with a variety of new and improved phenotypes, relating to (for example) suspension culture, signalling pathway activation and cellular lifespan. Once new cell lines have been engineered, you will characterise them using a wide variety of methods, including flow cytometry, microscopy and transcriptomics. Within the scope of cell engineering for cultivated meat, there will be freedom to select and suggest your own research projects, and to become acquainted with new techniques and approaches. There will be ample opportunities to supervise PhD, MSc and BSc students in the group, and to become familiar with grant writing and funding acquisition. Careers advice and discussion will be available for both academic and industry-minded scientists. We are a friendly, collaborative group and are looking for highly motivated candidates with strong project management and communication skills. You will be joining a dynamic department with broad interests in biotechnology and synthetic biology across all domains of life. The research is funded as part of the Cellular Agriculture Netherlands Open Calls Programme, and will involve collaboration and coordination with various industrial parties and external experts. For more information, please refer to the Flack Group website and/or get in touch.  Job requirements  The ideal candidate will be an ambitious, independent researcher looking to make the next step in their career. We are looking for the following: PhD in cell biology, synthetic biology or a related field of biological sciences (essential). Strong background in molecular biology, cloning and genetic manipulation (essential). Prior experience with gene editing and/or cell engineering (e.g. CRISPR/Cas or related techniques – essential). Expertise with mammalian cell culture is desirable (but not mandatory, a strong background in bacterial or yeast engineering will also be considered if you’re eager to apply that knowledge towards cultivated meat!). Experience in relevant related techniques such as microscopy, transcriptomics or metabolomics (highly desirable). Strong collaboration, communication and project management skills.  TU Delft (Delft University of Technology)  Working at TU Delft means contributing to solutions that really make a difference.  For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow.  These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.  At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional.  Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.  Faculty Applied Sciences  With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor’s and specialist Master’s programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.  Click here to go to the website of the Faculty of Applied Sciences.  Conditions of employment  Duration of contract is 2 years. Temporary. A job of 36-40 hours per week.  Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities. An excellent pension scheme via the ABP.  The possibility to compile an individual employment package every year.  Discount with health insurers on supplemental packages.  Flexible working week.  Every year, 232 leave hours (at 38 hours). You can also sell or buy additional leave hours via the individual choice budget.  Plenty of opportunities for education, training and courses.  Partially paid parental leave  Attention for working healthy and energetically with the vitality program.  Will you need to relocate to the Netherlands for this job? TU Delft is committed to make your move as smooth as possible! The HR unit, Coming to Delft Service, offers information on their website to help you prepare your relocation. In addition, Coming to Delft Service organises events to help you settle in the Netherlands, and expand your (social) network in Delft. A Dual Career Programme is available, to support your accompanying partner with their job search in the Netherlands.  .  Additional informationFor more information about this vacancy or our research group, please contact Dr. Joshua Flack (J.E.Flack@tudelft.nl). Position is envisaged to start around the end of 2026.       Application procedureAre you interested in this vacancy? Please apply no later than 2 August 2026 via the application button and upload the following documents only: CV (max 4 pages) Cover letter (max 2 pages). The next step in the process,

PhD in soil fauna supporting multifunctionality in regenerative agriculture

Your function The Ecology & Evolution section at the Amsterdam Institute for Life and Environment (A-LIFE) at Vrije Universiteit Amsterdam is accepting applications for a PhD position with focus on soil animal ecology. The section Ecology & Evolution answers fundamental ecological and evolutionary questions regarding the relationship between organisms and their environment at the full array of hierarchical levels: from molecular ecology to ecosystem research.  Location: Amsterdam, The Netherlands, co-supervised by The Soil Biology Group at Wageningen University. Are you interested in a PhD focusing on the role of the soil fauna in regenerative agriculture? Working with pioneer regenerative farmers across the Netherlands, this PhD will investigate which combinations of practices can support healthy multi-functional soil fauna communities. This PhD will quantify the role of soil fauna in supporting a range of soil functions for eight different regenerative agricultural business systems, working with 40 plus regenerative farms. The research will include questions like: 1) How do different soil fauna communities contribute to multi-functionality? 2) Can we recommend different combinations of management practices to enhance soil fauna diversity and associated multi-functionality? 3) What are the best indicators for wider monitoring of soil fauna and their functions in regenerative systems?  There is steadily growing pressure on agriculture and the entire food system to increase global production while promoting sustainability in terms of farmers’ incomes, soil health, input use, and environmental and climate impact. Regenerative agriculture is a promising avenue to support a healthy, multi-functional and future-proof soil and farming system. Together with regenerative Dutch farmers, ReGeNL is developing a future-proof agricultural sector in which agriculture goes hand in hand with soil health and nature restoration, and a good revenue model for farmers. Between now and 2030, ReGeNL will start the transition to regenerative agriculture with 1000 farmers. The aim is to make regenerative agriculture the new normal by 2040. This PhD is one of 19 PhDs to support the monitoring, modelling and valuing of regenerative farms in the Netherlands. This large-scale transdisciplinary project (ReGeNL), which started in 2024, will assess which combinations of practices are adopted/recommended for 8 different types of regenerative agriculture systems. The project aims to be an accelerator for the transition to a regenerative, profitable and socially supported agricultural sector. As part of this project, we monitor and model a range of different regenerative agricultural systems to understand which combinations of practices work for a range of agricultural, socio-economic and environmental outcomes. The outcomes assessed include; soil health, water and air quality, biodiversity and socio-economic goals such as farm income, citizen involvement, animal welfare and much more. Moreover, we will study how performance on these outcomes can be valued in food system governance.  As PhD you will work to support research and teaching activities within the A-LIFE section Ecology & Evolution. The role will encompass a variety of tasks including: Your duties conduct field and lab research measurements and quantification of soil invertebrate diversity analyse links between soil fauna diversity and key ecosystem functions developing a biodiversity indicator tool teaching in a BSc or MSc course on a topic related to the PhD Your profile a completed master’s degree in a field related to the topic the PhD project (e.g. biology, environmental science, agricultural science, or an adjacent field) knowledge or experience in (soil fauna) community ecology, with affinity for field work excellent writing and presenting skills affinity with societal challenges in the domains of agriculture and food systems motivation to work in a transdisciplinary project with many project partners and farmers experience with or interest in quantitative research methods enthusiasm to work in academic teams Dutch proficiency (or willingness to learn) As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset. We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements. What do we offer? A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you: a salary of € 3.059,00 (PhD) and maximum € 3.881,00 (PhD) gross per month in the fourth year, for a full-time employment an employment contract of initially 1 year. If there is sufficient perspective, this will be extended to a total of 4 years. Your dissertation at the end of the fourth year forms the end of your employment contract. We also offer you attractive fringe benefits and arrangements. Some examples: A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata. 8% holiday allowance and 8.3% end-of-year bonus solid pension scheme (ABP) contribution to commuting expenses a wide range of sports facilities which staff may use at a modest charge About us About the departmentThe sub-department A-LIFE /Ecology & Evolution offers a stimulating international research environment with world-class academic reputation, and excellent state-of-the-art facilities. Research in the department covers a wide range of fundamental and applied research topics, including stress ecology, species interactions, evolutionary adaptation, symbiotic interactions, climate change and ecosystem functioning. Our strength lies in the ability to integrate studies of adaptive changes across the entire range of biological organizational levels. About the Soil Biology Group, Wageningen University and ResearchThe Soil Biology group integrates knowledge on soil biota across a range of scales from the microbe to the globe. Our mission is “to explore the potential of life to increase the quality of soil”.  Our aim is to advance

Scientist/Senior Scientist – Innovation Pilot Lead – 2Blades Group

Role Overview The successful candidate will work closely with scientists and business development managers across the 2Blades laboratories at The Sainsbury Laboratory (UK) and the University of Minnesota (USA) to identify and address market-driven challenges in crop protection and trait development. The role will focus on designing, building, and validating innovative technologies, methods, and proof-of-concept solutions that address industry needs and enable new products and approaches. Drawing on expertise in molecular biology, technology development, high-throughput experimentation, computational approaches, and AI-driven tools, the successful candidate will tackle challenging biological and technical problems and translate ideas into practical solutions. Working with a high degree of independence, they will drive projects from concept to implementation, manage multiple initiatives simultaneously, and collaborate effectively across multidisciplinary teams to deliver practical, scalable solutions. Essential Qualifications and Experience PhD in plant biology, molecular biology, biotechnology, computational biology, or a related discipline. Strong expertise in molecular biology and experimental design. Demonstrated ability to develop and implement novel technologies, methods, assays, or workflows. Strong computational and data analysis skills, including the application of bioinformatic and AI-driven tools. Broad understanding of modern molecular and computational approaches, including applications of protein engineering and structural biology. Demonstrated ability to identify opportunities for innovation, evaluate emerging technologies, and translate ideas into practical solutions. Excellent critical thinking, creativity, and problem-solving skills. Strong organisational and project management skills, with the ability to manage multiple priorities simultaneously. Excellent communication, collaboration, and stakeholder engagement skills. Ability to work independently and drive projects from concept to implementation. Commitment to maintaining high standards of data quality, record-keeping, and laboratory practice. Desirable Qualifications and Experience Experience with high-throughput experimentation, automation, or assay development. Experience applying AI or advanced computational approaches to biological research. Experience working with commercial partners or translating research into applied outcomes. Experience with crop improvement, plant-pathogen interactions, or agricultural biotechnology. Experience with transient expression systems, including protoplast assays. Additional Essential Requirements Ability to maintain confidentiality and ensure the security of sensitive information where appropriate. Adherence to the organisation’s core values of trust, accountability, creativity, and excellence. Appointment Details Salary will be within the UEA Grade 7 salary scale between £38,784 and £47,389 per annum, depending on qualifications, skills, and experience. Applicants who require visa sponsorship may be eligible, subject to individual assessment and UK immigration requirements. This is initially being offered as a two year contract with possibility of extension. About The Sainsbury Laboratory (TSL) The Sainsbury Laboratory (TSL) is a world leader in plant and microbial science that is dedicated to making fundamental discoveries in the science of plant-microbe interactions. TSL has expanded its scientific mission not only to continue providing fundamental biological insights into plant-pathogen interactions, but also to deliver novel, genomics-based solutions that will significantly reduce losses from major crop diseases, especially in developing countries. About 2Blades 2Blades is USA based charitable organization that advances solutions to crop losses by merging cutting-edge scientific discovery with delivery in the field, contributing to a more resilient, sustainable, and productive global food supply. 2Blades establishes and manages development programs addressing significant unsolved crop disease problems and delivers outcomes to downstream implementation partners. It conducts these programs in its own laboratories and in collaboration with leading research institutions around the world. For more information please visit www.2Blades.org We offer 30 days annual leave, a generous pension scheme and the opportunity to develop skills and knowledge. We are located on an attractive campus offering cultural and recreational activities. We are committed to creating and promoting a diverse and inclusive workforce and we provide a supportive working environment for all colleagues. How to Apply Click the ‘Apply’ button on this page quoting the reference code below.Applicants should provide a CV, including the names and contact details of two or more referees, and a covering letter of no more than one A4 addressing the selection criteria. If you wish to discuss this vacancy please contact Human Resources HR@tsl.ac.uk Reference: KW03/2026 Closing date: 3rd August 2026 Apply Now

Research Assistant (Signalling)

  We are seeking an enthusiastic Research Assistant with some experience with mammalian cell culture techniques to join the Samant Lab in the Signalling Programme at Babraham Institute, Cambridge. The research in the lab focuses on two key hallmarks of human ageing—loss of proteostasis, and accumulation of cellular senescence—and this project directly tackles the relationship between these two in the context of tissue function and degeneration with age.  For more information on the work of the group, please visit: https://www.babraham.ac.uk/our-research/signalling/rahul-samant and https://samantlab.github.io/. The successful candidate will receive hands-on training in isolation and culture of different primary human cells from patient lung tissues, and in differentiation of these cells into 2D and 3D tissue-like structures (e.g., organoids and air-liquid interfaces). The candidate will then perform functional assays of proteostasis, senescence, and ageing-related dysfunction in these complex structures. This position is suited for a candidate with an interest in the fundamental biology of ageing, and is looking to learn and help further develop cutting-edge human models of ageing and senescence.     The ideal candidate will have a BSc or MSc in the biological sciences, with experience in basic molecular/cell biology and mammalian cell culture. They will also have excellent organisation, as this post requires co-ordination with the local hospital tissue bank to obtain time-sensitive patient material, as well as timely sample processing and maintenance. All necessary training for success of the project will be offered by experts at Babraham Institute and University of Cambridge. The post-holder will also have opportunities to develop further their molecular and cell biology skills (e.g., CRISPR editing; super-resolution microscopy), according to their career development goals. For example, all former pre-doctoral researchers in the Samant Lab have directly gone on to PhD programmes; therefore, this position could be especially appropriate for applicants looking to upskill and gain experience in a full-time research environment prior to doctoral training. This is a limited-term appointment with funding for this post expected to be available for a period of 1.5 years.  A full job specification and role requirements can be found attached to this vacancy.  Informal enquiries can be addressed to Rahul Samant (rahul.samant@babraham.ac.uk). The Institute has joined the Technician Commitment initiative, which is a commitment to support the recognition, visibility, sustainability and career development of our research support community, which includes the BSU, Scientific Facilities, Computing, Stores & Purchasing, Technical Services, Health & Safety and the Research Assistant communities. Closing date for applications is Friday, 31st July 2026 at 12pm.  However, we reserve the right to close the vacancy early depending on the volume of applications received. The Babraham Institute welcomes applications from all sections of society.  Apply Now

Postdoctoral Fellow – Neuroscientist

About us The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.  The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.  About the Cancer-Neuroscience Lab The Li lab explores how the nervous and immune systems interact in cancer and how these insights could unlock approaches to treatment. Using advanced mouse models and tissue culture systems, the team investigates how neuroimmune crosstalk shapes cancer development and progression, with a focus on how the nervous system influences immune responses in tumours. About the Project We are seeking a Postdoctoral Fellow to spearhead a project tackling one of the major challenges in cancer research: What is the role of the nervous system in cancer? Can we harness this interaction to treat cancer? The Postdoctoral Fellow will drive their own projects, while collaborating on other projects (both internally and externally) and guiding PhD students in their research. What you’ll be doing You will be responsible for: Designing experiments and research strategy in consultation with the PI Carrying out experiments and analysing data Keeping accurate and timely records of their work Engaging in professional development and growth Liaise with external collaborators Presenting work at Lab meetings, conferences and consortium meetings Drafting manuscripts for publication Click to see the full job description Click to find out more about the Cancer-Neuroscience Lab About you Essential: (Minimum criteria*) PhD (or near completion) in Neuroscience. Hands-on experience with in vivo / animal models. A strong publication record demonstrating scientific impact. Proven ability to design experiments and interpret data rigorously. Excellent communication and presentation skills. Ability to work both independently and collaboratively within multidisciplinary teams. A proactive, curious and resilient approach to research. Desirable Background in brain circuits or body-brain axis. Experience in neural modulation, neuronal tracing, electrophysiology, behaviour studies, single cell analysis. Experience working with genetically engineered mouse models. Experience in international, cross-disciplinary collaborations. About Working at the Crick Our values   Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!  We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.  We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.  We are collegial. We show respect for one another, work cooperatively and support the wider community.  At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we’ll make reasonable adjustments if you need them – just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: ruby.oluwafemi@crick.ac.uk. Find out more about life at the Crick. What will you receive?   At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:  Visas: Applicants for this role will be eligible for sponsorship to work in the UK  Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.  Pension Scheme: Defined contribution pension with employer contributions of up to 16%.  Health & Well-being:  24/7 GP consultation services.  Occupational health services and mental health support programs.  Eye care vouchers and discounted healthcare plans.  Work-Life Balance:  Back-up care for dependents.  Childcare support allowance.  Annual leave purchase options.  Crick Networks offering diverse groups’ support, community and inclusive social events. Perks:  Discounted gym memberships, bike-to-work scheme, and shopping discounts.  Subsidised on-site restaurant and social spaces for team interaction. Career support: A Post-doc to PI programme and other career development activities Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.   We reserve the right to withdraw this advert at any given time due to the number of applications received.  Apply Now

Scientist in clinical nutrition/gastroenterology

About the position A two-year 50% position as Scientist (SKO 1109) with background in clinical nutrition and/or gastroenterology is available at the Norwegian Coeliac Disease Research Centre, Institute of clinical medicine, University of Oslo.  The position is part of a multi-PI project split between the research groups of Professor Ludvig M. Sollid at the Department of Immunology, Institute of Clinical Medicine, Faculty of Medicine, Professor Knut Lundin at Department of transplantation medicine, Institute of Clinical Medicine, University ofOslo and Dr. Jorunn Stamnæs at the Proteomics Core Facility at Oslo University Hospital and University of Oslo. More about the position  The position is funded by Coeliac UK as part of a research project that will explore whether low-level gluten exposure (i.e. levels below the current definition of gluten free diet) can cause gut inflammation and gut damage in subjects with coeliac disease.  Specifically, we will in a placebo-controlled oral gluten challenge trial seek to determine whether repeat low-dose of gluten can induce immune activation and low-level gut inflammation.  The project builds upon recent data from the Centre (Stamnæs et al J Clin Invest 2025 PMID 40828615) that identifies a central role for interferon gamma in the induction of gut damage and remodeling.  In this project we will perform multiparameter flow-cytometry ofgut biopsies collected from patients subjected to low-dose gluten challenge as well as short-term ex vivo biopsy cultures to determine the source of inflammatory cytokines and experimentally establish a mechanistic link between immune cell activation, cytokine secretion and gut inflammation and remodeling in response to dietary gluten.  This project will rely on advanced cell biology methods including establishment ex vivo short-term intestinal biopsy culture followed by down-stream processing and analysis by methods such as flow cytometry, microscopy imaging and mass spectrometry-based proteomics. The successful applicant will join a world leading research environment on celiac disease with a strong track record in mucosal immunology, cell biology and tissue processing.  The specific tasks for the scientist will focus on recruitment of patients, screning for eligibility and clinical microchallenge with gluten.  The candidate will work in a multidisciplinary team with access to relevant training and support. The workplace will be in the research group of prof. Knut Lundin at the Department of transplantation medicine at Oslo University Hospital – Rikshospitalet.  Office facilities will be offered at Department of nutrition, University of Oslo.  The duration of appointment is 2 years. Qualification requirements The applicants must hold PhD in clinical nutrition, biology, immunology or a related field Experience with gluten challenge studies of coeliac disease patients is a requirement Experience and knowledge on human mucosal immunology is strong advantage Fluent oral and written communication skills in English. Good written and oral proficiency in Norwegian (or another Scandinavian language). If the employee cannot document skills in Norwegian, Swedish, or Danish at level A2 upon employment, UiO will offer Norwegian language training. The employee must complete training equivalent to at least 15 credits by the end of the employment period. We need different perspectives in our work  UiO is an open and internationally oriented comprehensive university that strives to be an inclusive and diverse workplace and academic environment. You can read more about UiO’s work on equality, inclusion, and diversity at uio.no. We fulfill our mission most effectively when we draw upon our variety of experiences, backgrounds, and perspectives. We are looking for great colleagues—could you be the next one? We will provide appropriate accommodations should you need them. Relevant adjustments may include modifications to working hours, task adaptations, digital, technical, or physical adjustments, or other practical measures. If you have an immigrant background, a disability, or CV gaps, we encourage you to indicate this in the job application portal. We always invite at least one qualified candidate from each group for an interview. In this context, disability is defined as an applicant who identifies as having a disability that requires workplace or employment-related accommodations. For more details about the requirements, please refer to the Employer portal (Norwegian). The selections made in the job application portal are used for anonymized statistics that all state employers include in their annual reports. More information about gender equality initiatives at UiO can be found here. We hope you will apply for the position with us.  We offer  An exciting research environment with opportunities for academic development. Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its richopportunities for culture and outdoor activities. Membership in the Statens Pensjonskasse, which is one of Norway’s best pension schemes with beneficial mortgages and good insurance schemes. Good welfare schemes. Opportunity of up to 1.5 hours a week of exercise during working hours. A workplace with good development and career opportunities.  Salary in position as Scientist, position code 1109 in salary range NOK 650 000 to 750 000 depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund Read more about the benefits of working in the public sector at Employer Portal. Application Your application should include: Application letter Letters of recommendation CV A complete list of publications Transcripts and certificates Letters of recommendation Contact information for 2-3 references Your CV must be entered in Jobbnorge’s CV form and cannot be submitted only as an attachment. This requirement is intended to ensure correct documentation and record-keeping in accordance with the Public Administration Act, Section 15. Application with attachments must be submitted via our recruitment system Jobbnorge, click “Apply for this job”. When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language. General information Please note that we are unable to add documentation after the application deadline. As the deadline applies equally to all applicants, this policy ensures equal treatment throughout the recruitment process. If you experience difficulties uploading documents in Jobbnorge, please contact their customer service: Phone: +47 75 54

Senior Engineer in Bioimage Processing

About the position  We are seeking a highly skilled, dedicated and research-oriented candidate for a temporary position as Senior Engineer (SKO 1181) in bioimage processing at the Institute of Clinical Medicine.  The position is associated with the Center for Cancer Cell Reprogramming (CanCell).  The position is funded by the IT Department at the University of Oslo, through the IT-Hub project “BioImage Processing Hub (BIP-Hub)”, a network supporting bioimaging core facilities at the University of Oslo. The facilities are located at Institute for Cancer Research (Radiumhospitalet), Department of Microbiology (Rikshospitalet), Institute of Basic Medical Sciences (Gaustad), Department of Biosciences (Blindern Campus), and Norwegian Centre for Molecular Medicine (Oslo Science Park).  The main focus of the Senior Engineer is to guide, teach and assist researchers at the different imaging nodes (detailed above) with tasks and challenges related to analyses, processing, and visualization of complex multidimensional imaging data.  The Senior Engineer will collaborate with current node-associated imaging experts as well as with a USIT System Engineer who will be responsible for advanced image processing infrastructure (local and remote), maintenance of image processing software packages and licenses.  Finally, the Senior Engineer will organize and run image processing teaching sessions and workshops for node users. The position is available immediately.  End-date for the project is 30.06.2027.  Responsibilities Set up bioimaging pipelines together with users. Perform analysis of multidimensional image data (time lapse, z-stack). Extract qualitative and quantitative information from images (e.g. colocalization of 2-3 fluorophores). Handle and perform 3D analysis of large image and data volumes. Set up on-the-fly bioimage processing workflows for microscopy. Establish a centralized bioimage analysis repository. Organize targeted workshops, and guide people to use open-source solutions.  Qualifications Qualification requirements Relevant education from a university or university college at a minimum level equivalent to a master’s degree, in cell biology, information technology, optics, or related fields. Extensive relevant professional experience and specialized competence a high level adapted to the functions of the position are prerequisites. Extensive experience with Bioimage processing. Possess coding experience with image processing applications.  Experience with various open-source software for image processing (i.e. Napari, ImageJ). Experience with biological microscopes and optics, as well as image acquisition pipelines. Experience with statistical analyses. Preferred selection criteria Prior experience with working in a bioscience research environment. Experience with statistical computation, modeling and simulations. Good communication skills in working with end users, and documented teaching skills (workshops, one-on-one). Understanding of IT-infrastructure for optimal communication with the USIT System Engineer. PhD in cell biology, information technology, optics, or related fields.  Personal skills  The ideal candidate should be service-minded, with strong collaboration and communication skills.  Personal suitability will be emphasized in the recruitment process. We need different perspectives in our work  UiO is an open and internationally oriented comprehensive university that strives to be an inclusive and diverse workplace and academic environment. You can read more about UiO’s work on equality, inclusion, and diversity at uio.no. We fulfill our mission most effectively when we draw upon our variety of experiences, backgrounds, and perspectives. We are looking for great colleagues—could you be the next one? We will provide appropriate accommodations should you need them. Relevant adjustments may include modifications to working hours, task adaptations, digital, technical, or physical adjustments, or other practical measures. If you have an immigrant background, a disability, or CV gaps, we encourage you to indicate this in the job application portal. We always invite at least one qualified candidate from each group for an interview. In this context, disability is defined as an applicant who identifies as having a disability that requires workplace or employment-related accommodations. For more details about the requirements, please refer to the Employer portal (Norwegian). The selections made in the job application portal are used for anonymized statistics that all state employers include in their annual reports. We hope you will apply for the position with us.  We offer  Exciting and meaningful tasks in an organization with an important societal mission, contributing to knowledge development, education, and enlightenment that promote sustainable, fair, and knowledge-based societal development. A pleasant and stimulating scientific work environment. Good welfare schemes. Opportunity of up to 1.5 hours a week of exercise during working hours. A workplace with good development and career opportunities.  Membership in the Statens Pensjonskasse, which is one of Norway’s best pension schemes with beneficial mortgages and good insurance schemes. Salary in position as job Senior Engineer, position code 1181 in salary range NOK from 660 000 to 860 000, depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund. Read more about the benefits of working in the public sector at Employer Portal. Application Your application should include: CV Application letter A complete list of publications Transcripts and certificates Contact information for 2-3 references Your CV must be entered in Jobbnorge’s CV form and cannot be submitted only as an attachment. This requirement is intended to ensure correct documentation and record-keeping in accordance with the Public Administration Act, Section 15. Application with attachments must be submitted via our recruitment system Jobbnorge, click “Apply for this job”. When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language. General information Please note that we are unable to add documentation after the application deadline. As the deadline applies equally to all applicants, this policy ensures equal treatment throughout the recruitment process. If you experience difficulties uploading documents in Jobbnorge, please contact their customer service: Phone: +47 75 54 22 20 or Email: support@grade.com  The primary method of communication throughout the process will be e-mails and messages through the recruitment system Jobbnorge. When you receive a notification of a message in Jobbnorge, please log in to read it, as it may be important. The best qualified candidates will invited for interviews. Applicant lists can be published in accordance with Norwegian Freedom of Information Act § 25. When you apply for a position with us, your name will appear

PhD project at KU Leuven: Development of novel integrative spa-tial multi-omics approaches to investigate tumour heterogeneity in melanoma

An innovative Doctoral NetworkSPAtial single-CEll omics research training for MELanoma precision medicine SPACE-MEL is an EU-funded MSCA Doctoral Network advancing the next generation of spatial single-cell omics technologies for precision medicine. Bringing together leading European universities, technology providers, clinical partners and innovative companies, the programme will address key experimental and computational challenges currently limiting the clinical translation of spatial biology. By integrating multi-omics approaches, enabling the transition from 2D to 3D tissue analysis and developing advanced data interpretation methods, SPACE-MEL aims to unlock deeper insights into cellular organisation and disease mechanisms. The network will train 15 Doctoral Candidates through an interdisciplinary programme spanning spatial imaging technologies, molecular biology, computational biology, pathology and biomarker discovery. Through cross-sectoral secondments, hands-on research and comprehensive transferable-skills training, SPACE-MEL will equip a new generation of researchers with end-to-end expertise in spatial biology and strengthen Europe’s leadership in this rapidly evolving field. Contributing partners in SPACE-MEL: Erasmus University Medical Centre Rotterdam (NL), University of Zurich (CH) KU Leuven (BE), Intelligent Biodata (ES), University of Navarra (ES), University of Manchester (UK), Aspect Analytics (BE), University of Perugia (IT, ) Università di Firenze (IT), Maria Sklodowska-Curie National Research Institute of Oncology (PL), Lunaphore Technologies SA (CH), , Diatech Pharmacogenetics S.r.l (IT), , Sanofi-Aventis Research & Development SA (FR), , Spotlight Pathology Ltd (UK), BioLizard NV (BE), , AtlasXomics Inc. (USA), , SkylineDx B.V. (NL), , AlpenGlow Biosciences Inc. (USA), Stellaromics Inc. (USA), accelopment Schweiz AG (CH). For more information: https://cordis.europa.eu/project/id/101311007. Project One PhD position is available at the Department of Oncology, Laboratory of Lipid Metabolism and Cancer, within the KU Leuven Institute for Single Cell Omics, at KU Leuven. The project has a duration of 36-months. PhD project at KU Leuven: Development of novel integrative spa-tial multi-omics approaches KU Leuven is offering a PhD position focused on the development of innovative integrative spatial multi-omics approaches to investigate tumour heterogeneity in melanoma. The successful candidate will develop and optimize a comprehensive workflow that integrates spatial transcriptomics, proteomics, and lipidomics. The project combines expertise in lipid metabolism and lipidomics with cutting-edge spatial omics technologies, including Mass Spectrometry Imaging (MSI), Raman microscopy, MILAN, Xenium, Visium, and COMET. The research has two closely linked objectives: 1. Development of an integrated spatial multi-omics workflow for simultaneous transcriptome, proteome, and lipidome profiling. 2. Application of the workflow to melanoma samples to generate novel diagnostic and therapeutic insights into tumour heterogeneity and disease progression. This interdisciplinary project offers a unique opportunity to work at the interface of molecular biology, advanced imaging, omics technologies, and cancer research, contributing to the development of next-generation approaches for precision oncology.  Supervisor: Prof. Dr. Johannes SwinnenProf. Swinnen is the Head of the Laboratory of Lipid Metabolism and Cancer and leads the KU Leuven Lipidomics Core Facility, Lipometrix. KU Leuven provides a strong interdisciplinary research environment through the Leuven Institute for Single Cell Omics (LISCO), which brings together researchers from more than 65 groups across KU Leuven, University Hospitals Leuven and VIB, offering access to advanced single-cell, spatial omics, pathology, lipidomics and computational biology expertise. Co-supervisors:    Dr. Maria Mantas, Aspect Analytics, Belgium (Industry)    Dr. Volodimir Olexiouk, BioLizard NV, Belgium (Industry) Secondments:    4 months at Aspect Analytics, Belgium (supervisor: Dr. Maria Mantas)    3 months at BioLizard NV, Belgium (supervisor: Dr. Volodimir Olexiouk) Profile Eligibility criteria:  According to the EU rules for the EU-Doctoral Network projects, the recruited researchers must comply with the following conditions: are – at the date of recruitment – doctoral candidates (DCs) (i.e not already in possession of a doctoral degree at the date of the recruitment). Researchers who have successfully defended their PhD thesis but not yet received their degree are not considered eligible; DCs can be of any nationality; DCs must comply with the following mobility rule: they must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 36 months immediately before their recruitment date. Research Field/Requirements: MSc degree in biology, biomedicine, biotechnology or natural sciences, analytical chemistry, biochemistry or comparable; Interest in research on lipid metabolism, spatial omics and melanoma/oncology; Hands-on expertise in (spatial) lipidomics, spatial multi-omics and data analysis tools is a plus; Good command of spoken and written English;  Ambitious, hard-working and accurate. Offer The DC will receive a 36-month scholarship to cover her/his living costs. The gross amount of the doctoral scholarship is based on a living allowance that is dependent on a country correction coefficient which takes into account the cost of living in the country of the recruiting institution. For Belgium, the gross amount of the doctoral scholarship (tax-free) will be approximately €3.120,64 per month if the DC is single with no dependent family members. It will be higher if the DC has a registered partner without income and/or dependent child(ren); it will be lower if the DC has a registered partner with income. The cost of all training activities, including all expenses related to travel and accommodation to attend annual meetings and other network organized events will be paid by the network through the Horizon Europe MSCA-DN grant. DCs will have access to a dedicated workspace and to research facilities. Bench/consumables costs to execute the research project will be covered by the institutions. Interested? How to apply?     Interested candidates should apply by submitting the required documents via the KU Leuven platform. Please note that only applications submitted through this online system will be considered. Ensure that all requested documents are included, as incomplete applications will not be reviewed.        • Motivation letter in English indicating their interest in the project and how this fits with their research ambitions.     • Detailed curriculum vitae, including personal information (gender, age, nationality), studies, list of publications, participation in research projects, extracurricular training, mobility, other qualifications or relevant skills.     • Certified copy/ies of Academic Degree/s in the original language along with a certified translation into English, and/or Diploma Supplement.     • Certified copies of official Academic Transcripts

Glycosphingolipid Dysregulation in Congenital Disorders of Glycysolation (CDG)

The project is embedded within the department of development and regeneration KU Leuven and the Laboratory of Applies Mass Spectrometry – Metabolomics expertise center.The candidate will collaborate closely with experts in clinical genetics, metabolomics, lipidomics, glycobiology and systems biology. The research environment provides:– Access to unique international collections of CDG patient samples– State-of-the-art mass spectrometry infrastructure– Advanced multi-omics platforms– Extensive international collaborations– Opportunities for conference participation and international training Project Congenital disorders of glycosylation (CDG) comprise more than 200 individually rare inherited metabolic disorders and represent one of the most rapidly expanding groups of inborn errors of metabolism. While abnormalities of protein glycosylation have traditionally been considered the primary disease mechanism, many CDG patients present with severe neurological manifestations that remain only partially understood. Recent work from our research group has identified glycosphingolipids (GSLs), including gangliosides, as a potentially critical but underexplored disease mechanism in CDG. Because glycosphingolipids constitute the majority of glycan structures in the central nervous system and are essential for neuronal development, signalling and synaptic function, understanding their dysregulation may open entirely new therapeutic avenues. This PhD project forms part of a larger translational research programme aimed at developing mechanism-based treatments for CDG. The successful candidate will work at the intersection of rare disease research, neuroscience, systems biology, metabolomics and lipidomics. RESEARCH OBJECTIVES Objective 1 – Defining glycosphingolipid abnormalities in CDG The candidate will perform comprehensive glycosphingolipid and ganglioside profiling in an extensive collection of patient-derived fibroblasts representing multiple CDG subtypes. Using state-of-the-art lipidomics and tracer-based metabolomics, metabolic bottlenecks and pathway rerouting events will be identified. Treatment options will be explored. Objective 2 – Investigating disease mechanisms and therapeutic opportunities Key findings will be validated in neuronal-relevant cellular models generated through CRISPR-mediated genetic engineering and pharmacological perturbation approaches. Multi-omics integration (lipidomics, metabolomics, proteomics and transcriptomics) will be used to identify pathogenic mechanisms and nominate therapeutic interventions, including glycosphingolipid supplementation and drug repurposing strategies. The project builds upon unique patient cohorts, extensive preliminary data, and internationally recognised expertise in congenital disorders of glycosylation. Profile We are looking for a highly motivated candidate who: – Holds (or will soon obtain) a Master’s degree in Biomedical Sciences, Biology, Medicine, Bioengineering, Biochemistry, Biotechnology, Pharmaceutical Sciences, Bioinformatics or a related discipline – Has obtained excellent academic results – Demonstrates a strong interest in rare diseases, metabolism, neuroscience or molecular medicine – Has an interest in advanced laboratory techniques and data analysis – Possesses strong communication and scientific writing skills – Is able to work independently while thriving in a collaborative multidisciplinary team – Is fluent in English Experience with cell culture, molecular biology, mass spectrometry, bioinformatics, programming or omics technologies is considered an asset but is not mandatory. RESPONSIBILITIES – Conduct innovative research leading to a PhD degree – Perform experiments involving cell culture, lipidomics, metabolomics and molecular biology – Analyse and integrate complex multi-omics datasets – Present research findings at national and international meetings – Publish research in high-quality scientific journals – Participate in national and international collaborations – Support supervision of Master’s thesis students Offer KU Leuven offers a stimulating international research environment with excellent training opportunities. The successful candidate will join a dynamic team of clinicians, PhD students, postdoctoral researchers and technicians working on rare metabolic diseases and translational therapeutic development. Successful completion of the programme will lead to the degree of Doctor of Biomedical Sciences. FUNDING AND APPOINTMENT – Fully funded PhD position (4-year trajectory subject to successful evaluation according to KU Leuven regulations) – Competitive salary according to KU Leuven doctoral scholarship scales – Expected start date: flexible, preferably October 2026  – Location: Leuven, Belgium Interested? For more information please contact Prof. dr. Peter Witters, mail: peter.witters@kuleuven.be or Prof. dr. Bart Ghesquière, mail: bart.ghesquiere@kuleuven.be. APPLICATION PROCEDURE To apply, please submit: – Motivation letter – Curriculum vitae – Academic transcripts – Contact details of two academic referees You can apply for this job no later than August 10, 2026 via the online application tool KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address. Job application procedure Working conditions Career opportunities Do you have a question about the online application system? Please consult our FAQ or email us at apply@kuleuven.be

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