Fixed-term

Jawaharlal Nehru UniversitySchool of Life ScienceNew Delhi 110 067                            Project : “Uncovering Hidden Heritability: Epigenetic Responses to Geminivirus Infection in Tomato” Position:  Junior Research Fellow (One) Salary : – @37000/- per month plus HRA (as per ANRF rules and guidelines for JRF). Essential Qualifications : Master degree in Biological / Life Sciences with at least 60% (or equivalent marks) or equivalent degree in any branch of biological/ Life sciences having qualified CSIR/UGC NET can apply. Final year /semester students of M Sc having qualified CSIR/UGC NET may also apply, subject to the submission of M Sc final mark sheet / passing certificate at the time of interview, if shortlisted. Desirable Qualifications : Research experience in the area of plant virus interactions / protein-protein interactions/plant molecular biology. Duration: The Project will continue till March 2031. The above-mentioned position is completely temporary and is co-terminus with the project. Appointed person will be expected to stay in the lab for the entire period of the project. General information:- The competent authority may select candidate in the lower position against the above post depending upon the qualifications and experience of the candidate and reserves the right to relax any of the qualification(s) in case the candidate is found otherwise well qualified by the Selection Committee. Applications (soft copy only) are invited from suitable candidates to apply by sending a cover letter detailing experience, with CV, reprints and names with complete address (including e-mail) of three references on or before June 20, 2026 by e-mail to :-virologylabslsjnu[at]gmail[dot]com.  Prof. S. Chakraborty 

Offer Description Dr. Philipp Sondermann is Joint Group Leader and Head of the Laboratory for Drug Evolution at IMol Polish Academy of Sciences and the Institute of Organic Chemistry and Biochemistry in Prague. He received his B.Sc. and M.Sc. degrees in Chemistry from the University of Heidelberg and did undergraduate research with Nobel laureate Prof. David MacMillan at Princeton University. He received his PhD degree in Organic Chemistry from ETH Zurich, working with Professor Erick M. Carreira, where he completed the total synthesis of natural products Mytilipin B and Janustatin A. He is the recipient of the Dr. Sophie-Bernthsen Scholarship for excellence in undergraduate studies and was awarded the ETH Medal for his dissertation. He subsequently worked as an SNF Postdoctoral fellow in the group of Prof. Peter G. Schultz at Scripps Research in La Jolla on the reprogramming of Botulinum proteases for targeted degradation of intrinsically disordered proteins. The Laboratory for Drug Evolution led by Dr. Sondermann combines techniques from organic chemistry and synthetic biology to enable Darwinian evolution of drug molecules.    Research Interests – Website Drug discovery is a slow, expensive, and labor-intensive process. Large sums are invested into screening compound libraries to identify initial hits and structurally optimizing these initial compounds for human therapeutic use. However, traditional medicinal chemistry often restricts itself to low structural complexity molecules that cover only a small portion of the theoretically accessible chemical space. This limitation also restricts the types of proteins that can be pursued as targets, currently leaving a significant portion of the human proteome “undruggable.” Many organisms in nature produce defensive chemicals to enhance their fitness. Some of these products have been used clinically to treat various human diseases, including cancerous malignancies, helminthic diseases, and bacterial infections. However, these therapeutic properties in humans are largely coincidental and only indirectly evolutionarily selected. Novel, “non-natural” metabolites with structures specifically designed for human therapeutic use can enable the specific targeting of a much broader range of currently undruggable protein targets. In the Laboratory of Drug Evolution, we employ Darwinian evolution and emulate Nature’s strategies to identify novel drug structures tailored for human use. We utilize strategies and techniques from organic chemistry and molecular biology to reroute and accelerate the drug discovery process. Our research also explores the use of new therapeutic modalities to target intrinsically disordered proteins (IDPs), a class of proteins characterized by the absence of a stable fold. IDPs remain largely undruggable, but they play crucial roles in human diseases such as Parkinson’s disease, Alzheimer’s disease, and cancer. As new means to combat these diseases, we leverage sequence-specific proteases to reduce the intracellular levels of these disordered proteins and improve patient outcomes. JOB OFFER Profile of candidates/requirements: – MSc degree in chemistry, biochemistry, molecular biology, or related fields in natural sciences and life sciences. – Familiarity with laboratory techniques in at least one of the following disciplines: organic chemistry, synthetic biology, molecular biology, biochemistry. – Very good command of English. – Motivation and passion for experimental work. We offer: – Job type (employment contract/stipend): Full-time position, fixed-term scholarship contract, admission to doctoral school after the probation period. – Remuneration/month:  5.500 PLN net/month (4.900 PLN net/month on the probation period). – The position can start on the 1st of July 2026. – Work in an active team in an excellent scientific environment. – Comprehensive training in synthetic biology, chemistry, and molecular biology. – Access to the state-of-the-art equipment and facilities. – Participation in courses and conferences. – Dual PhD appointment at IMol Polish Academy of Sciences in Warsaw and Institute of Organic Chemistry and Biochemistry (IOCB) Prague with the work being performed in Warsaw, Poland. Description of the tasks in the project: We are seeking a curious and motivated PhD student to join our team at the Laboratory of Drug Evolution. The project aims to investigate and establish the use of systems for continuous hypermutation in drug discovery. The project involves a wide range of techniques, with a focus on molecular and synthetic biology, complemented by analytical techniques from cell biology and chemistry. The project’s objective is to develop strategies for using in vivo hypermutation in the continuous evolution of proteases. The goal is to reprogram sequence-specific proteases to degrade intrinsically disordered proteins, which are key players in human disease. The successful candidate will be responsible for designing and conducting experiments, analyzing data, interpreting results, writing scientific manuscripts, and preparing the PhD thesis. While the project has defined research goals, it also offers flexibility and scope for independent thinking and creative exploration. This position provides an excellent opportunity to gain comprehensive training at the interface of chemistry and synthetic biology, and to develop skills in advanced experimental design and scientific communication within a stimulating and collaborative research environment. Required documents (in English): – Cover letter with short descriptions of your research experience/projects. – CV – List of publications – 2 Reference contacts Application Form

Offer Description Our lab studies how RNA metabolism and pre-mRNA splicing shape the molecular identity of stem cells during the earliest stages of development. In this project, we ask how the spliceosome – one of the most complex cellular machineries – is dynamically regulated in C. elegans germ stem cells, and how changes in its composition influence cell fate. The project has three aims: Map the dynamics of splicing factors and alternative splicing events across different regions of the germline, and identify the events critical for germline regulation. Determine how individual splicing factors regulate germ cell fate, using genome and protein-level perturbation approaches to generate worms with altered splicing factor levels and characterise the resulting phenotypes. Identify genes that undergo alternative splicing during germline specification and assess the physiological relevance of these events. Beyond its fundamental significance, this work may inform future approaches to reproductive disorders and germ cell-derived cancers. Your Role: You will design and carry out experiments combining molecular biology, genetics, microscopy, and biochemistry, working both independently and in close collaboration with the team. You will also contribute to experimental planning, data interpretation, basic bioinformatic analysis, and the preparation of publications. We are looking for Essential: – MSc (or equivalent) in molecular biology, biochemistry, genetics, developmental biology, or a related life science – Strong foundational knowledge of molecular biology, genetics, and cell biology – Hands-on experience with standard molecular and genetic techniques (e.g., PCR, cloning, gel electrophoresis, microscopy, Western blotting) – Excellent written and spoken English – A solid scientific track record relative to career stage – Ability to work independently and as part of a team Desirable: – Prior experience with C. elegans (training will be provided if not) – Familiarity with RNA biology, gene expression regulation, or stem cell and developmental biology – Experience with CRISPR/Cas9, transcriptomics or proteomics, confocal microscopy, or basic bioinformatics (e.g., RNA-seq or MS data analysis) We offer: – Job type (employment contract/stipend): Full-time position, fixed-term contract, up to 48 months, – Remuneration/month: 5.000 PLN net/month, – The position starts on the 1st of October 2026 or as soon as possible, – Work in an active team in an excellent scientific environment, – Comprehensive training in molecular biology, genetics, transcriptomics, proteomics, and biochemistry, – Access to the state-of-the-art equipment and facilities, – Participation in courses and conferences, – Medical package and social benefits (sports card, holiday bonus, 36 days of paid holiday per year). Required documents (in English): – Cover letter, – CV, – List of publications (if applicable), – Reference contacts (please do not send generic letters, contact details only). If you think you are the person we are looking for, please apply by filling in this form: https://forms.gle/Exoy7iw4U8cYLL9C6 Application Form

Maj Institute of Pharmacology Polish Academy of Sciences (hereinafter referred to as the Institute or IP PAS) announces the competition for an assistant (Postdoctoral Researcher) (F/M/X) to conduct scientific research within the framework of the National Science Centre project OPUS 26, no. 2023/51/B/NZ7/02360, entitled “Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabetes and obesity.” Research Topic Description: Semaglutide, a drug used in the treatment of type 2 diabetes and obesity, has gained global popularity, particularly among women of reproductive age, raising concerns about its potential impact on fetal development. The planned research aims to investigate the effects of semaglutide on neurodevelopmental processes using in vivo models. It is hypothesized that exposure to this compound during the first trimester of pregnancy may affect the development of the offspring’s nervous system by modulating synaptic plasticity, neuronal connectivity, and cognitive functions through mechanisms associated with GLP-1R receptor signaling pathways. The project foresees comprehensive biochemical, molecular, and behavioral analyses to provide an in-depth assessment of the potential neurotoxic effects of semaglutide. A person for the position of an assistant (post-doc) (F/M/X) should meet the following conditions: A doctoral degree in biological, pharmaceutical, medical sciences or related fields, obtained at an institution other than the Institute of Pharmacology PAS, not earlier than 7 years before the year of employment in the project, or completion of at least a 10-month, continuous, and documented postdoctoral fellowship abroad. The 7-year period may be extended by the documented time spent on long-term (over 90 days) medical leave or rehabilitation benefits due to incapacity for work. In addition, this period may be extended by the number of months of parental or childcare leave granted under the provisions of the Polish Labour Code, and for women, by 18 months for each child born or adopted, if this method of accounting for career breaks is more advantageous; The project’s Principal Investigator must not have been doctoral supervisor or assistant supervisor of the person submitting the offer; During the period of employment in the project, the candidate may not receive any other salary funded from direct costs of research projects financed by the National Science Centre (NCN); During the period of employment in the project, the candidate may not be employed under an employment contract by another employer, including employers based outside of Poland; Proficiency in performing basic in vivo procedures, including subcutaneous and intraperitoneal injections, as well as tissue and organ collection for further analyses; Experience in conducting behavioral tests on animal models (e.g., cognitive, anxiety, depression-like, locomotor, and coordination tests), with knowledge of their design, execution, and interpretation; Practical knowledge of methods such as gene expression analysis (qPCR), immunoenzymatic assays (ELISA), RNA/DNA/protein isolation, electrophoresis, and western blotting; Experience in implementing research projects, independently analyzing and interpreting results, preparing manuscripts, and presenting and discussing findings in public; Knowledge of statistical analysis of experimental data. Proficiency in the use of statistical and graphical software such as Statistica, GraphPad Prism, ImageJ, or equivalent, and the ability to select appropriate statistical tests for different data types and interpret the results; Completed training required for persons planning and conducting procedures and euthanizing animals used for scientific or educational purposes, in accordance with the provisions of the Polish Act on the Protection of Animals Used for Scientific or Educational Purposes (Journal of Laws of 2023, item 465, of 2025, item 1795); Advanced command of the English language, both spoken and written; Exemplary ethical conduct. Additional assets will include: Knowledge of programming languages R and/or Python for the purpose of biological, bioinformatic, and statistical data analysis, including the use of libraries dedicated to genomic data analysis. Knowledge of the Polish language. SCOPE OF DUTIES: Conducting in vivo experiments using animal models to assess the effects of semaglutide on central nervous system development; Performing subcutaneous and intraperitoneal injections, as well as collecting tissues and organs for further analyses; Carrying out behavioral tests in rodents (e.g., cognitive, anxiety-like, depressive-like, locomotor, and coordination tests); Performing molecular and biochemical analyses; Analyzing and interpreting experimental data, including selection of appropriate statistical tests and data visualization; Preparing research reports, scientific manuscripts, and conference presentations; Maintaining laboratory documentation in accordance with applicable standards and ensuring compliance with ethical regulations concerning animal experimentation; Strict adherence to the Code of Ethics for IP PAS employees; Compliance with internal regulations and official directives in force at the IP PAS. TERMS OF EMPLOYMENT: Employment within the project under a full-time employment contract (task-based work system) for a period of up to 48 months. The salary will be in accordance with the NCN OPUS 26 regulations, i.e. approximately PLN 140,000 gross gross per year. The planned starting date of employment is July 2026.  REQUIRED DOCUMENTS: Application for employment for the above-mentioned position together with a cover letter with a description of scientific interests; Information about the candidate in accordance with Appendix 1 to the Form; Personal questionnaire for a person applying for employment in accordance with Appendix 2 to the Form; Copy of the doctoral diploma or certificate confirming the award of the doctoral degree; Short self-report (autobiographical statement of research achievements); Copy of the certificate of completion of training for persons planning and conducting procedures and euthanizing animals, in accordance with the provisions of the Polish Act on the Protection of Animals Used for Scientific or Educational Purposes (Journal of Laws of 2023, item 465, of 2025, item. 1795); Contact details of referees who have agreed to provide information about the candidate and who agreed to be contacted; Certificate of English language proficiency, if available; Statement on the primary place of employment and affiliation of research and publications, in accordance with App. No. 3 to the Form; Information on the processing of personal data in accordance with Appendix 4 to the Form; A declaration of impeccable ethical attitude in accordance with Appendix 5 to the Form. Applications along with the required documentation should be sent in electronic form to the following e-mail address: ifpan@if-pan.krakow.pl  by 18.06.2026. The title of the message should indicate which competition the application concerns:“Competition

Maj Institute of Pharmacology Polish Academy of Sciences (hereinafter referred to as the Institute or IP PAS) announces the competition for the position of an assistant (F/M/X) at the Department of Brain Biochemistry. We are seeking a highly motivated individual interested in conducting innovative research and supporting research projects carried out at the Department of Brain Biochemistry IP PAS. We offer a stimulating professional environment, friendly atmosphere and an individualized approach to work organization while respecting the so-called “work–life balance”. At the same time, we expect determination and a positive attitude toward implementing projects classified as “high risk / high gain”. A person for the position of an assistant (F/M/X) should meet the following conditions: Hold a professional Master’s degree in medical or related fields; Have a minimum of 5 years of experience with advanced fluorescence and confocal microscopy techniques and with primary in vitro cultures; Possess very good practical knowledge of biochemical and molecular biology techniques (including isolation and quality assessment of proteins and RNA, molecular cloning, Western blot, use of the SimplePlex, ELISA, qRT-PCR, immunofluorescence platforms, as well as knowledge of working with human and iPSC-derived cells); Have knowledge of image analysis software (ImageJ, CellProfiler); Hold a proven scientific record documented by publications in journals with international reach; Have completed research internships at foreign scientific institutions; Demonstrate the ability to independently manage research projects and independently analyze and interpret results, prepare manuscripts and publicly present and discuss results; Be motivated to expand scientific knowledge and have scientific curiosity; Demonstrate willingness to conduct own scientific research and projects; Possess the ability to organize one’s own work and teamwork and take responsibility for assigned tasks; Have a fluent knowledge of English; Demonstrate an impeccable ethical attitude. Additional advantages: Doctoral degree in medical sciences or related fields; Confirmed active involvement in teaching activities; Experience and authorization to work with laboratory animals (mice, rats); Knowledge of spoken and written Polish. RESPONSIBILITIES:  Development of research activities in areas consistent with the scientific profile of the Maj Institute of Pharmacology Polish Academy of Sciences; Planning and conducting research experiments, implementation of ongoing scientific projects; Preparation and archiving of research results; Implementation of new research methods; Preparation of research projects and acquisition of research funding; Strict adherence to the code of ethics of Polish Academy of Sciences employee; Compliance with the regulations and orders in force at the IP PAS TERMS OF EMPLOYMENT: Employment in the project under a full-time employment contract. Remuneration in accordance with the remuneration regulations of the IP PAS.  REQUIRED DOCUMENTS: Application for employment for the above-mentioned position together with a cover letter with a description of scientific interests; Information about the candidate in accordance with Appendix 1 to the Form; Personal questionnaire for a person applying for employment in accordance with Appendix 2 to the Form; Copy of Master’s degree diploma or a copy of the doctoral diploma or a certificate of obtaining a doctoral degree (if available); Short self-presentation text; A copy of the certificate of completion of training in conducting research with the use of laboratory animals (if available); Contact details of persons who can provide references and who agreed to be contacted; Opinion of the current scientific supervisor; Certificate of English language proficiency (if available); Statement on the primary place of employment and affiliation of research and publications, in accordance with App. No. 3 to the Form; Information on the processing of personal data in accordance with Appendix 4 to the Form; A declaration of impeccable ethical attitude in accordance with Appendix 5 to the Form. Applications along with the required documentation should be sent in electronic form to the following e-mail address: ifpan@if-pan.krakow.pl  by June 18, 2026. The title of the message should indicate which competition the application concerns: “Competition – Assistant (F/M/X), Dept. of Brain Biochemistry IP PAS”. The winner of the competition will be selected from among those meeting the formal requirements based on the analysis of documents and possible invited interviews. Please be advised that we will contact only selected candidates and we will not return the submitted documents. We reserve the right to void the contest without giving any reason. For additional information, please contact: Grzegorz Kreiner, PhD – grzegorz.kreiner@if-pan.edu.pl  Date of the competition announcement – May 29, 2026 Deadline for submitting applications – June 18, 2026 Date of the competition settlement – June 29, 2026