Fixed-term

Do you want to contribute to top quality medical research? The successful candidate will work on childhood neuroblastoma and paraganglioma in the research group headed by Susanne Schlisio: The research is performed in an interdisciplinary setting with strong collaboration with clinical departments and other national and international research groups. We are seeking a motivated, creative post-doctoral candidate interested in exploring drivers of intratumor heterogeneity and phenotypic plasticity in childhood neuroblastoma and paraganglioma. Intratumor heterogeneity and high plasticity account for therapy resistance. Causes of plasticity cell state transitions during tumor progression remain poorly understood. Currently, there is no effective treatment that addresses cancer heterogeneity. Systematic characterization of dynamic properties of intratumor heterogeneity and phenotypic plasticity can guide treatment strategies and improve clinical outcome for cancer patients. We aim at elucidating the origin and heterogeneity of paraganglioma and childhood neuroblastoma by developing a new analytic and experimental approach based on spatial transcriptomics and single-cell transcriptomics with integrated mass spectrometry. We use organoids, cell lines and generate novel tumor mouse model systems and include human tumors to perform comparative differentiation trajectory analysis, to make predictions and, finally, to perform preliminary validations of envisioned tumor differentiation strategies. In addition, we are also looking for motivated, creative post-doctoral candidates interested in cancer metabolism with knowledge in mitochondrial biology, biochemistry and molecular biology. We currently defining how mitochondrial dynamics and mass is related to cancer therapy resistance. Your mission We offer a highly interdisciplinary environment , integrating computational biology with cancer and developmental biology. We develop new analytic and experimental approaches based on single nuclei transcriptomics and spatial transcriptomics to explore intra-tumor heterogeneity and plasticity. Furthermore, we generate novel tumor mouse model systems and include human tumors to perform comparative differentiation trajectory analysis, to make predictions and, finally, to perform preliminary validations of envisioned tumor differentiation strategies. For examples of how the research can be conducted, please see: https://pubmed.ncbi.nlm.nih.gov/34493726/ https://pubmed.ncbi.nlm.nih.gov/35760869/ https://pubmed.ncbi.nlm.nih.gov/33385330/ Your profile To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier. Qualifications: We are looking for a highly self-motivated person with a strong background in cellular and molecular biology with a keen interest in nervous system tumors. Experience in mitochondrial biology, molecular and cellular biology techniques, confocal imaging and mouse modeling is highly desired; and good ability to communicate in English (written and verbal) is required.  A documented ability to independently carry out experimental research projects is required We are looking for independent and driven candidates who have at least one first-name publication in a peer-reviewed journal. The successful applicants may have experience in one or several of the following techniques/models: Molecular, cellular and biochemical techniques, e.g. cloning, qPCR, Western blot and immunohistochemistry, Bioinformatics, mouse as a model system, Organoid cultures, Mitochondria research  Merits: It is considered as a merit if the applicant has experience in flow cytometry, imaging, laboratory animal work or bioinformatics analysis tools. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Location: Solna Application An employment application must contain the following documents in English or Swedish: PhD certificate A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page) KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T The application is to be submitted through the Varbi recruitment system. Apply at the latest 24th June. The employment is for 2 years with possibility of extension.  Apply Now

Do you want to contribute to improving human health? The Lindström research group offers a creative and inspiring environment characterised by expertise, curiosity, and close collaboration. Our vision is to conduct high-quality medical research that improves survival and clinical management for patients with breast cancer. We are part of the Department of Oncology and Pathology at BioClinicum, where basic, translational, and clinical cancer research are brought together in a stimulating interdisciplinary setting. Karolinska Institutet is one of the world’s leading medical universities, and since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel Laureates in Physiology or Medicine. To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required. The research group A doctoral position is available in Linda Lindström’s research group. We are seeking a highly motivated doctoral student to join a research team dedicated to improving the understanding of breast cancer and the factors associated with the development of metastatic disease. A central question in our work is why some patients are at particularly high risk of developing metastases. Breast cancer is a highly heterogeneous disease with respect to tumour biology, metastatic potential, and the timing of metastatic progression. For example, younger premenopausal women are known to have a higher and long-term risk of developing metastatic disease than postmenopausal women, yet the biological mechanisms underlying this difference are not well understood. A particular focus of the Lindström group is to better understand these differences, together with timing of metastasis. We and others have shown that patients with breast cancer have a persistent long-term risk of metastatic disease that remain 20–30 years after diagnosis. To address these questions, the group uses a range of complementary approaches, primarily by integrating tumour-related information from patient cohorts and clinical studies. The group has also recently established a cell laboratory, which will provide opportunities for involvement in experimental research for candidates with an interest in this area. The group has a strong network both within Karolinska Institutet and internationally, with frequent collaborations with research groups in the USA, the Netherlands, Norway, and Spain, all connected by a strong translational focus. Linda Lindström is Deputy Head of the Department of Oncology and Pathology, where the research group is based. Until recently, she also served as Co-Director of the Breast Cancer Theme Center (BRECT) at Karolinska Institutet and as Chair of the national translational breast cancer network SWETribe, which brings together both preclinical and clinical researchers. For further information about our work, please consult the following selection of publications from our group: Danielsson and Lindström et al, JNCI, 2026Johansson and Lindström et al, JCO, 2022Johansson and Lindström et al, JNCI 2025Yu and Lindström et al, JAMA Oncol, 2019 The doctoral student project and the duties of the doctoral student The doctoral studies correspond to four years of full-time study. The research programme for this doctoral position will include analytical as well as practical work, in addition to scientific writing, courses, seminars, and presentations. The overall objective of the project is to improve prediction of who will develop metastatic disease and die from breast cancer by identifying key tumour characteristics that influence this risk, using unique clinical cohorts with long-term follow-up. Ultimately, the aim is to improve clinical management already at the time of primary diagnosis by identifying patients at high and low risk of later developing metastatic disease. We hypothesise, and have previously shown, that risk factors influencing prognosis during the first 10 years after diagnosis differ from those associated with late or long-term risk of metastatic breast cancer. In addition, younger premenopausal women have a poorer prognosis than older postmenopausal women, and their risk may also be influenced at least partly by different biological factors. We have also shown that intra-tumour heterogeneity of oestrogen receptor (ER) expression influences the risk of fatal breast cancer. As a continuation of this work, the project will investigate the importance of intra-tumour heterogeneity at single-cell resolution, which is now possible through the use of spatial proteomics together with novel image-analysis methods that we will combine and further develop. Endocrine therapy is the standard and foundational treatment for ER-positive breast cancer. However, it is well established that approximately half of patients do not derive substantial benefit from this treatment, and the long-term benefit among those who initially respond remains unclear. In this doctoral project, we will continue our efforts to understand how menopausal status at diagnosis, tumour characteristics, and intra-tumour heterogeneity influence both the timing and pattern of benefit from endocrine treatment. The doctoral student will play an important role across all parts of the selected projects. Responsibilities will include literature review, statistical analysis, interpretation of results, scientific writing, and presentation of data. In addition, the role will involve molecular analyses (primarily planning and coordination) and more practical aspects of the project, such as coordinating the collection of potentially missing but necessary patient information. The position therefore requires flexibility and a strong interest in interdisciplinary work across clinical oncology, pathology, biostatistics, epidemiology, and molecular biology. Your supervisors have broad expertise in biostatistics, bioinformatics, epidemiology, oncology, and molecular biology. What do we offer? A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern

Do you want to contribute to improving human health? Our research group offers a unique opportunity to work at the intersection of neuroscience and psychology, advancing fundamental and translational insights into the human sense of smell and its relevance to mental health. You will join a well-funded, internationally visible, and highly collaborative research environment, working closely with leading experts and benefiting from strong methodological, conceptual, and career mentorship. Through active collaborations with prominent international research groups, you will gain opportunities for international exchange and build a strong global research network that supports your long-term career development. Your mission We are searching for a highly motivated Research Assistant in Neuroimaging to join a large-scale multimodal, multisite research project focused on advanced neuroimaging and data-driven neuroscience. The position will involve neuroimaging data curation; structural and functional MRI preprocessing, quality control, and analysis, as well as organizing, cleaning, and integrating other relevant data from multiple sources. The successful candidate will contribute to building robust and reproducible workflows that ensure data accuracy, accessibility, and long-term usability for future research and collaborative analyses. Your profile To be eligible for this position as a research assistant, you must hold a master’s degree in neuroscience, biomedical engineering, psychology, cognitive science, data science, or a related field. It is particularly meritorious that the applicant has shown Experience in neuroimaging data management Skills in programming or scripting languages, such as Python, MATLAB, or Bash It is meritorious that the applicant has shown Familiarity with The Brain Imaging Data Structure (BIDS) Experience in data curation, preprocessing, and quality control Experience with established neuroimaging analysis tools, such as SPM, FSL, FreeSurfer, fMRIPrep, MRIQC or other tools Experience working with large-scale multimodal or multisite datasets We value strong organizational, analytical, and communication skills, as well as the ability to work collaboratively in an interdisciplinary research environment, are essential. The working language of the research group is English, and the candidate is expected to communicate fluently in both spoken and written English. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Solna Application KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T. The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.  Permanent position is initiated by a six months trial period. Apply Now

Do you want to contribute to top-quality medical research? Staffan Strömblad’s research group at the Department of Medicine, Huddinge, is looking for a Research Assistant. The research group conducts research on how the mechanical properties of tissue affect cancer development. We use experimental models and patient tissues for these studies. The aim is to increase the understanding of cancer development and to exploit opportunities to use the new knowledge for clinical diagnostics. Your role The research assistant will participate in projects regarding early cancer development by performing tissue labeling and analyzing these labels digitally, primarily through the use of the software QuPath. The position is a fixed-term contract of 6 months with the possibility of a 6-month extension. The scope is 70%. Who are you? You have a Master’s degree in life sciences. You have good experience in tissue labeling and quantitative digital tissue analysis with QuPath. You also have documented good knowledge in immunology and experience in analyzing different types of resident immune cells in tissues. We place great importance on personal suitability. What do we offer? A creative, international and inspiring environment filled with competence and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to drive the development of knowledge about life and work for better health for all. Here we conduct successful medical research and have the largest range of medical education in Sweden. As a university, Karolinska Institutet is a government agency. This means that you receive good benefits through our collective agreement. Employees at KI are also offered the opportunity for a flexible working method. This means that if the business you work in allows, you can work part of your working hours remotely. You are also allowed to exercise freely in our modern wellness facilities where trained staff are on site.   Location:   Flemingsberg Campus            Application KI applies individual and differentiated salary setting according to our collective agreements RALS and RALS-T.  The application must be made via the recruitment system Varbi. In this recruitment you apply with your CV without a cover letter. In the application form you will instead be asked to answer a few questions about why you are applying for the job.  In the case of permanent employment, Karolinska Institutet applies a 6-month probationary period. Apply Now

Do you want to contribute to improving human health? Research area Detection of high-risk recurrence and optimization of salvage strategies after radiation treatment in prostate cancer and establishing a dedicated training program for table side assistants in urologic robotic surgery. Your mission We are recruiting a Research Coordinator to strengthen our project on optimizing salvage strategies after radiotherapy in prostate cancer. The successful candidate will contribute both to scientific analysis and to the clinical implementation of research findings. This is a temporary employment during 1 year.  Key responsibilities include: Linking PSMA PET/CT imaging reports with national quality registries and performing advanced statistical analyses. Refining definitions of biochemical recurrence, evaluating predictors of progression, and assessing salvage treatment strategies. Designing structured training programs to translate research outcomes into clinical practice, with a focus on robotic urologic surgery. Developing and implementing educational modules for surgical and clinical staff to accelerate adoption of new diagnostic and treatment strategies. Contributing to manuscript preparation, dissemination of findings, and coordination of interdisciplinary collaborations. Your profile Graduate-level education in life science, medicine or related field. Clinical experience in urologic robotic surgery and tableside assistance. Strong background in hands-on training of multidisciplinary clinical staff. Proven expertise in academic publishing. Assessment criteria It is particularly meritorious that the applicant has demonstrated Excellent proficiency in English, both written and spoken. Ability to work independently as well as collaboratively in a multidisciplinary research environment. International and interdisciplinary work experience Documented experience in project management and delivery of results within set timelines. Great importance is placed on personal suitability. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. In addition to this, you will also get: A unique opportunity to combine research excellence with clinical translation, shaping both science and practice in prostate cancer management. A dynamic, internationally competitive academic environment at Karolinska Institutet. The possibility to directly impact patient outcomes, clinical guidelines, and surgical education. Collaboration with world-leading experts in cancer research, robotic surgery, and medical training. Location: Solna Application The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.  Apply Now

Do you want to contribute to top quality medical research? Overview of the Position The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are looking to recruit 5 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. giving the fellows lot of opportunities to make new connections both within Karolinska Institutet and internationally within the field of diabetes and metabolism. The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the fall 2026, though some flexibility with the start date might be possible. Short running title of project: Mitochondrial quality control in type 2 diabetes Research Project: Role of optineurin in mitochondrial quality control and metabolic flexibility in type 2 diabetes A hallmark feature of type 2 diabetes is reduced skeletal muscle mitochondrial content. Exercise improves mitochondrial volume and quality, however emerging evidence from our laboratory suggests that this may be compromised in individuals with type 2 diabetes. The purpose of this project is to define the molecular mechanisms underlying defective mitophagy in type 2 diabetes. By using exercise as a physiological perturbation, this work will establish how mitochondrial quality control is regulated in human skeletal muscle, and how this regulation is altered in type 2 diabetes. Specifically, this project will investigate whether the mitophagy receptor optineurin contributes to exercise-stimulated mitochondrial quality control and metabolic flexibility in skeletal muscle. Furthermore, we will investigate how distinct optineurin phosphorylation signatures, that emerge after exercise in individuals with and without type 2 diabetes, regulate optineurin function and therefore mitophagy. These studies will define how optineurin regulates skeletal muscle mitophagy and reveal a mechanism underlying impaired mitochondrial quality control in type 2 diabetes, identifying a potential therapeutic target to restore metabolic flexibility. Key responsibilities of the selected applicant: Plan, manage and conduct an agreed academic research project and associated activities. Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. Develop research questions, analyse detailed and complex quantitative data from a variety of sources, and contribute original ideas for new research projects. Coordinate multiple aspects of work to deliver novel research data in accordance with established timelines set between you and the Principal Investigator. Adapt existing and develop new scientific techniques and experimental protocols to support research. Regularly write research articles at an international level for peer-reviewed journals, book chapters, and reviews. Formally present your research and represent the research group at internal, national and international conferences and meetings, either with other members of the team or alone. Informally present your research to the group at established meetings. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques. Selection Criteria Essential  A PhD in a medical/biological subject. Strong background in skeletal muscle biology, mitochondrial dynamics, or exercise physiology. Documented experience with cell biology and/or animal physiology approaches. Strong analytical skills and experience in statistical analysis and data interpretation. The ability to manage your own academic research and associated activities. A strong CV, having published in high impact journals and presented at international meetings. Ability to contribute ideas for new research projects and research income generation. Ability to work with meticulous attention to detail. An enthusiastic interest in diabetes research. Evidence of excellent interpersonal skills and leadership, with the ability to communicate research ideas and results in a clear and logical way and the ability to confidently and effectively interact with colleagues and the broader research community. Strong verbal and written communication skills in English. A conscientious and enthusiastic working approach. Excellent planning, organizational and problem-solving skills. Desirable  Documented programming experience in R and/or Python Each Fellowship is for two years. To be eligible for employment as a post-doctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Working at Karolinska Institutet For further information about working at Karolinska Institutet, rules for visa/residence permit, insurance and accommodation please see: https://staff.ki.se/international-staff  Location: Solna Application If you consider that you meet the selection criteria, click on the Login and apply button on this page and follow the on-screen instructions to register as a user. You will then be required to provide information in a number of screens with your

Do you want to contribute to top quality medical research? The Department of Laboratory Medicine consists of seven divisions and comprises advanced basic scientific, translational, and clinical research. In addition, it is one of the main educational departments at Karolinska Institutet. A postdoctoral position is available in the Division of Clinical Physiology. Our research aims to raise awareness of the relationship between physical activity and health and is conducted in close collaboration with the Unit of Clinical Physiology at the Karolinska University Hospital. Your mission We and others have shown that physical activity after a cancer diagnosis leads to maintained physical functioning and quality of life. In addition, current epidemiological, clinical and animal-model based evidence support the role of exercise to enhance therapeutic efficacy, reduce recurrence and improve survival. However, very little is known about how exercise exerts its beneficial effects. In a recent publication, we showed that the immune system, and especially CD8+ T-cells, are instrumental for the anti-neoplastic effects of exercise and that exercise induced shifts in metabolite availability can alter immune cell function.  A postdoctoral position is available at the Department of Laboratory Medicine, in the lab of Ass Prof Helene Rundqvist for a highly motivated individual. For the project, we will combine animal models with human intervention trials to investigate the effects of high intensity exercise on CD8+ T-cell mobilization and function. The successful applicant will characterize CD8+ T-cell function after exercise both in vivo and ex-vivo, with specific regard to effector function, metabolism, t-cell receptor signaling and homing capacity. To accomplish this, the applicant will have access to state of the art human exercise facilities, animal models, and pre-clinical labs in an innovative and translational environment. Your profile To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier. We are looking for a candidate with extensive and documented experience in human exercise trials, multi-color flow cytometry and functional characterization of immune cells. Previous experience of in vivo and in vitro imaging techniques, metabolic profiling, and epigenetic characterization is considered a merit.  A keen interest in science and the ability to interact effectively and work productively in a team as well as a good ability to communicate in English is required. Emphasis will be placed on personal skills, knowledge, and abilities, as well as on documented previous work. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Location: Flemingsberg Read about the division of Clinical Physiology Application An employment application must contain the following documents in English or Swedish: PhD certificate A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page) The application is to be submitted through the Varbi recruitment system. Apply Now

Do you want to contribute to improving human health? The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. Our key words are multidisciplinary, bridging, national and international collaborations. We are currently seeking a research specialist to the research group of Margareta Wilhelm, although the work will be carried out in close collaboration with Professor Sonia Lain. Sonia Lain is affiliated with MTC’s Department of Tumor Biology, and in particular with activities within drug development. Description of the subject area One of the most challenging lines of investigation is the discovery of molecules that can be developed into medicines. I the project for the position, we establish the mechanism of action of our molecules and with this information we proceed to suggest and then test the potential use of these molecules to treat a specific disease.  As an employee at MTC and Karolinska Institutet, you will have the opportunity to become part of an interdisciplinary environment with a wide range of expertise. Your mission The general mission of Sonia Lain’s project is to discover potential medicaments for the treatment of disease with a special focus on cancer. The candidate will be involved in the experimental work that may lead to the use of an already selected molecule in the clinic. This will also involve the suggestion of companies and medical experts in the relevant diseases as well as contacting with them to understand and satisfy their requirements. Eligibility requirements For employment as Research Specialist at Karolinska Institutet, the eligibility requirements stated in the Guidelines for non-teaching positions at Karolinska Institutet are applied in relation to the established profile of employment. To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated research expertise as well as have documented postdoctoral research experience. Meritorious for the position: Having gained industry experience in drug discovery and preclinical evaluation, including both in vitro and in vivo work will be positively considered. Ability of building reliable experimental workflows and generating high-quality data, in order to reach the final aim; to add value at an early stage of the drug discovery process.  Having experience of the requirements necessary to reach the IND level with a molecule, that is understanding the requirements of companies is another important asset. This is a temporary position (substitute) for approximately three months. Assessment criteria After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Location:  Solna  Choose to work at KI – Ten reasons why Application We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents:  PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet’s qualifications portfolio. The application must be submitted through the Varbi recruitment system. KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T.  Apply Now

Do you want to contribute to top quality medical research? The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are now looking to recruit 5 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend. The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the fall of 2026, though some flexibility with the start date might be possible. Available research projects The following 5 projects are available (click each project to reach the corresponding job posting): Insulin resistance in skeletal muscle Early-Onset Type 2 Diabetes in Women Type 2 Diabetes and Parkinson’s Disease Mitochondrial quality control in type 2 diabetes Obesity Management Beyond the Scale Your profile To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Application You can do one of the following: a) go to this website https://ki.se/en/srp-diabetes/postdoctoral-fellowships to find more information about the postdoc program as well as detailed information on the projects and labs and the individual job postings with their online application form. b) Directly click on the individual projects titles above to find the corresponding job posting and online application form.

Do you want to contribute to better health for all? Overview of the Position The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are looking to recruit 5 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. giving the fellows lot of opportunities to make new connections both within Karolinska Institutet and internationally within the field of diabetes and metabolism. The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the fall 2026, though some flexibility with the start date might be possible. Short running title of project: Investigating the SNc–Vagus Nerve Axis in Type 2 Diabetes  and Parkinson’s Disease Pathogenesis Research Project Type 2 diabetes (T2D) is a major metabolic disorder associated with increased risk for neurodegenerative diseases, including Parkinson’s disease (PD). Recent evidence suggests that alterations in dopaminergic circuits may drive peripheral insulin resistance, contribute to dysregulated glucose metabolism, and promote α-synuclein (aSyn) aggregation, a hallmark of PD. The project aims to investigate the dynamic interactions between Substantia Nigra (SNc) dopaminergic neurons, vagus nerve (VN) activity, and aSyn pathology during the onset and progression of T2D. The project will combine longitudinal in vivo electrophysiology, dual-wavelength fiber photometry, high-fat diet models, and wireless transauricular VN stimulation (taVNS) to elucidate mechanistic links between metabolic dysfunction and PD onset. Key responsibilities of the selected applicant: We expect the successful candidate to be able to significantly contribute to the planning and management of their project(s), supervision of students, as well as the writing of manuscripts and navigation of the peer-review process. Selection Criteria Essential  PhD degree in Biomedical or Neuropharmacology Research or similar. Experience in Parkinson’s disease models, behavioral neuroscience, histology, gene and/or cell therapy development and in vivo preclinical evaluations. Certificate for animal experiment and project design. Extensive experience in data analysis and data presentation. High level of self-motivation and independence. Work well with others in a team. Willingness to supervise and share experience with students. Very good command of written and spoken scientific English. Each Fellowship is for two years. To be eligible for employment as a post-doctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement. Working at Karolinska Institutet For further information about working at Karolinska Institutet, rules for visa/residence permit, insurance and accommodation please see: https://staff.ki.se/international-staff  Location: Solna Application If you consider that you meet the selection criteria, click on the Login and apply button on this page and follow the on-screen instructions to register as a user. You will then be required to provide information in a number of screens with your application details, relating to your skills and experience. When prompted, please provide details of three references. You will also be required to upload a CV and Personal Letter which explains how you meet the selection criteria for the position. The Personal Letter (maximum two pages) should explain your relevant experience which may have been gained in employment, education, or you may have taken time away from these activities as illness, military service, work for labour unions or student organisations, parental leave or similar circumstances. Your application will be judged in part on the basis of how you demonstrate that you meet the selection criteria outlined above and we are happy to consider evidence of transferable skills or experience which you may have gained outside the context of paid employment or education. Please save all uploaded documents to show your name and the document type. The application is to be submitted through the Varbi recruitment system. The closing date for applications is midnight CEST on Friday 26th June, 2026. Apply Now