Fixed-term

Post-doctoral position to study organization, dynamics, and function of transcription condensates

Introduction UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility. unil.ch/work Presentation The Vastenhouwlab group (https://www.vastenhouwlab.org) at the Center for Integrative Genomics at the University of Lausanne invites applications for a postdoc position in transcription regulation, with a focus on the organization, dynamics, and function of transcription condensates. There is accumulating evidence for a new gene expression paradigm, in which genes and transcription factors cooperate to create specialized transcription bodies. These are dynamic liquids, with quick exchange of molecules between the condensates and the nucleoplasm. While these bodies have gained a lot of interest in recent years, they are generally hard to study because they are small, abundant, and short-lived. We discovered that in zebrafish embryos, transcription begins in two transcription bodies that are large, isolated, and long-lived (PMID: 33649325). These provide us with an excellent system to investigate how transcription bodies form (PMID: 36476751; PMID: 40650976; doi: https://doi.org/10.1101/2024.07.25.605169) and how they regulate the availability of machinery in the nucleus (PMID: 38589534). How the content and dynamics of these condensates contribute to transcription regulation, however, remains unclear. Job information – Expected start date: as soon as possible – Contract length: 1 year, renewable – Activity rate: 100% – Workplace: University of Lausanne, Dorigny campus Your responsibilities The successful candidate will work on a project aimed to study organization, dynamics, and function of transcription condensates using advanced microscopy and data analysis methods. The candidate will also have the opportunity to gain teaching and mentoring experience by contributing to undergraduate and graduate courses and supervising student research projects. Your qualifications – A PhD degree in any of the life sciences – Interest in transcription regulation, nuclear organization, and quantitative biology – Excellent scientific writing, communication, and interpersonal skills – Expertise in live imaging and analysis are strong assets What the position offers you You will be supervised by Prof. Nadine Vastenhouw, in a diverse, dynamic, and international research laboratory. You will work on your independent project but there is ample intellectual and technical expertise in the lab to make sure you are well-supported. The working language is English. unil.ch/work Contact for further information For further information, please contact Nadine.vastenhouw@unil.ch Your application Deadline: 15.04.26 Please submit your full application as a single PDF document comprising: – A cover letter in which you describe your research interests and experience, and clearly explain why you are interested in this particular position – A CV – A copy of your PhD degree certificate – Contact details for 2 or more referees Only applications through this website will be considered. Additional information UNIL is committed to: •    equality, diversity and inclusion within its community; •    ensuring an open and respectful environment that is conducive to personal development; •    offering working conditions that facilitate work-life balance; •    supporting early career researchers. unil.ch/equality unil.ch/families unil.ch/graduatecampus Apply Now

Research positions in Quantifying the of role soil erosion on phosphorus loads and eutrophication in European freshwaters

Applications are invited for a PhD fellowship/scholarship at Environmental Geosciences, University of Basel, Switzerland within the PhD Program Environmental Sciences. The position is available from 1 June 2026 or later. Your position Research area and project description: Soil erosion by water is a major contributor to eutrophication in freshwater systems, acting as an important source of phosphorus from land. While erosion–eutrophication links are widely assumed, quantitative evidence across spatial scales remains limited. Advancing soil and water protection therefore requires improved understanding of how farming systems, land management and erosion processes influence nutrient loading in rivers and lakes, as well as better identification of eutrophication hotspots across the EU. This PhD project will develop integrated and reproducible approaches to quantify and reduce soil- and sediment-driven nutrient pollution in European catchments. It will assess the role of soil erosion and land management in phosphorus transport and eutrophication, using monitoring data from the EU Water Framework Directive to calibrate and validate advanced sediment routing and modelling approaches. The research will also design a European-scale turbidity and sediment monitoring framework combining in situ observations and satellite remote sensing. The project directly supports EU policies including the Common Agricultural Policy, Soil Monitoring Law and Nitrates Directive, and contributes to the European Green Transition. It is an international collaboration between the University of Basel and the European Commission’s Joint Research Centre under the Collaborative Doctoral Partnerships programme. For further information and detailed task description please see link below. Your profile Qualifications and Specific competences: You hold, or are close to completing, a Master’s degree in ecology, soil science, agricultural, environmental or related sciences. You have a strong interest in soil erosion modelling and phosphorus-driven eutrophication, with experience in soil monitoring and erosion processes. Skills in GIS, spatial analysis of large scale data, modelling, remote sensing, and programming (R or Python) are desirable. You work independently, communicate effectively, are fluent in English, and are highly motivated and results oriented. Eligibility criteria Candidates should, prior to the start of the employment contract with the JRC: have the nationality of a Member State of the EU or a country associated to the EU Research Framework Programme in force or being resident in a EU Member State since at least five years. We offer you The place of employment is Environmental Geosciences, University of Basel, Switzerland, and the European Commission Joint Research Centre (JRC), Via Enrico Fermi, 2749, 21027 Ispra (VA), Italy. While employed at the JRC, the salary and benefits are those of a JRC Grantholder Category 20, following the Grantholder Rules. The annual gross salary will be around 45,000 Euro and is subject to national income tax. While employed at the University of Basel, the salary and benefits are according to the University of Basel rules. Application / Contact Please submit your complete application documents, including a letter stating your motivation and a short statement of research and teaching interests, experience and skills, a CV and contact details of at least two references via our online recruiting platform. Applications via Email will not be accepted. Application deadline is26th March 202623:59 CET. Preferred starting date is 1 June 2026. Applicants seeking further information please see https://duw.unibas.ch/de/umweltgeowissenschaften/ or contact: Professor Christine Alewell, christine.alewell@unibas.ch. For information about application requirements and mandatory attachments, please see our application guide https://joint-research-centre.ec.europa.eu/work-us/collaborative-doctoral-partnership-cdp-programme/cdp-programme-phd-candidates_en Apply Now

Research positions in Bioinformatics Scientist

The Laboratory for Biological Engineering (Prof. Randall J. Platt) at ETH Zurich in Basel, Switzerland develops technologies at the interface of biological engineering, molecular (DNA, RNA, protein) perturbation technologies, and functional genomics, and applies them to understand and treat disease. In support of these efforts, we are seeking a Bioinformatics Scientist to work closely with Professor Platt, guide the group’s computational research, contribute to ongoing projects, and pursue independent research directions aligned with the laboratory’s goals. Project background Our group builds high-throughput experimental platforms that require the development of novel computational methods. Two example areas in which the candidate would contribute are described below. 1. In Vivo Single-Cell CRISPR Perturbation Screens CRISPR perturbation screens, such as Perturb-seq, are transforming how we study gene function at scale. We recently developed an AAV-based method for direct in vivo single-cell CRISPR screening (Santinha, Nature, 2023) and are now expanding this approach to generate in vivo cell-type perturbation atlases, interrogate disease mechanisms, and identify therapeutic targets. These efforts produce large-scale, rich in vivo perturbation datasets. The computational challenges include building scalable and reproducible pipelines for guide demultiplexing and assignment, cell-type annotation using bespoke references, and downstream effect estimation at both the perturbation and gene levels, as well as developing biologically grounded perturbation prediction models incorporating machine learning. 2. Transcriptome Recording and Cellular History Reconstruction We are advancing our CRISPR-based transcriptional recording method (Schmidt, Nature, 2018; Tanna, Nature Protocols, 2020) that encodes transient cellular events into DNA and reads them out by sequencing. Computational challenges include detecting biological signals when applying Record-seq to complex in vivo environments (Schmidt, Science, 2022) — especially in the context of drug–host microbiome interactions — and developing dedicated tools and analytic workflows for the novel data modalities generated by Record-seq and related molecular technologies. Job description Working closely with Professor Platt and members of the laboratory — both experimental and computational — the successful candidate will play a central role in planning projects and experiments, developing computational methods, analyzing multi-omic datasets (including transcriptomics, metagenomics, metabolomics, and proteomics), reviewing results, and interpreting findings Beyond contributing to ongoing projects, the candidate will be expected to develop independent research directions aligned with the laboratory’s goals Responsibilities will also include publishing, grant writing, peer review, academic collaborations, industry partnerships, departmental service, research dissemination, and education The percentage of working time spent in any area will fluctuate based on priorities, but should on average be: research (70%), supervision of trainees (20%), service (10%) It is anticipated that the candidate will be hired at the Established Researcher (Oberassistent) level (see Scientific Functions at ETH Zurich). Further career progression to a permanent position is possible, and a career development plan with clear milestones and timelines will be put in place. Profile The ideal candidate will hold a PhD or equivalent in bioinformatics, computational biology, computer science, applied statistics, or a related field, with substantial (>6 years) postdoctoral or equivalent experience developing and applying computational methods to large-scale biological datasets. We are looking for someone who brings: Deep methodological expertise. A broad and current understanding of methods in bioinformatics and computational biology — including their strengths, limitations, and where the field is heading — along with the technical skills to independently design and execute projects that push these frontiers forward. Desirable technical skills are detailed in the application questionnaire Software development. A track record of developing and releasing well-documented computational tools and packages for use by the broader research community Leadership and mentorship. The ability to guide and develop trainees in the planning and execution of computational research projects Strong communication. The ability to clearly convey complex topics to both expert and non-expert audiences in conversation, writing, and presentations in English A record of impactful publication. Experience publishing computational work across diverse venues (journals and conferences), with a strong sense of how to craft a compelling narrative and navigate the publication process Grant writing ability. Experience designing and writing compelling, feasible, and fundable research proposals Visibility and independent contributions. A successful track record with recognized independent contributions to the field We offer The position is located in the Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich in Basel, Switzerland. The D-BSSE is a highly interdisciplinary department specializing in systems and synthetic biology, bioinformatics and data science, and engineering sciences. The department is centrally located within a biomedical research hub with close links to leading academic institutions (e.g., the Swiss Institute of Bioinformatics, the Friedrich Miescher Institute (FMI), and the Biozentrum and University of Basel) as well as major biotechnology and pharmaceutical companies (e.g., Novartis, Roche, Lonza, and Bayer). ETH Zurich is a global leader in science and technology and consistently ranks as one of the top universities in the world. chevron_right Working, teaching and research at ETH Zurich We value diversity and sustainability In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future. Curious? So are we. We look forward to receiving your application. Please submit the following as a single PDFby  24  March 2026 : Cover letter contextualizing your scientific background, skills, and interests, and articulating why you are interested in joining the group CV Diplomas and course transcripts Contact details of at least two referees Please submit your application online. Applications via email will not be considered. Further information can be found on our website. For questions about the position, please contact Prof. Platt(for questions only; please do not send applications via email). Additional dates: Initial Zoom call –  1 or 2 April 2026 : Shorlisted candidates will be invited for a brief introductory Zoom meeting. In- Person interview – 16 or 17 April 2026:

PhD scholarship in Microneedle-Enabled Biosensing

This PhD position requires a strong background in biomedical engineering, materials science, chemistry, or a related field. The candidate should have experience with biosensors, electrochemical techniques, or drug delivery systems, and an interest in smart hydrogels and microneedle technologies. Familiarity with microfabrication, flexible electronics, or wireless control systems is an advantage. Strong analytical skills, experimental independence, and the ability to work in interdisciplinary teams are essential, along with good scientific communication skills. The position offers hands-on training in advanced biosensing, smart materials, and transdermal delivery technologies, leading to high-impact publications and potential patents. The project provides excellent preparation for academic, industrial, or translational careers while contributing to personalized and clinically relevant therapeutic solutions. Responsibilities and qualifications The main purpose of this PhD position is to develop a closed-loop transdermal drug delivery platform for Parkinson’s disease. The project focuses on integrating real-time L-DOPA sensing with light-controlled release using microneedles and smart hydrogels. The goal is to enable precise, personalized therapy through continuous monitoring and adaptive drug delivery. The position contributes to innovative, clinically relevant biomedical technology with translational potential. Key tasks and responsibilities Design and fabricate microneedle-based transdermal delivery systems Develop and characterize electrochemical sensors for L-DOPA detection Engineer and test light-responsive hydrogels for controlled drug release Integrate sensing, delivery, and wireless control into a closed-loop system Perform in vitro and ex vivo experimental validation Analyze data and optimize system performance Disseminate results through publications, presentations, and reports Furthermore, you must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree. Approval and Enrolment The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation, and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and appointment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. The position is full-time, with a starting date of 1. September 2026 or as soon as possible thereafter. You can read more about career paths at DTU here. Further information  Further information may be obtained from Alireza Dolatshahi-Pirouz (aldo@dtu.dk) or Jakob Bardram(jakba@dtu.dk). You can read more about DTU Health Tech at www.healthtech.dtu.dk. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar, “PhD relocation to Denmark and startup“ Zoom seminar, for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. Application procedure  Your complete online application must be submitted no later than 15 May 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: A letter motivating the application (cover letter) Curriculum vitae Grade transcripts and BSc/MSc diploma (in English), including official description of the grading scale Links to any online resources, like source code, hardware design, videos, etc. A 2-minute video of yourself explaining why you are a fit for the position You may apply before obtaining your master’s degree, but you cannot begin before receiving it. Applications received after the deadline will not be considered. All interested candidates, irrespective of age, gender, disability, race, religion, or ethnic background, are encouraged to apply. As DTU conducts research in critical technologies, which are subject to special security and export control rules, open-source background checks may be conducted on qualified candidates for the position. Apply Now

Research Manager in Food Process Technology and Production Engineering

Are you passionate about food processing, food physics, and enabling high-quality research through strong scientific leadership and hands-on expertise? We are seeking a highly motivated and experienced Research Manager to join the Research Group for Food Production Engineering at DTU National Food Institute. This position plays a key role in the scientific, technical, and operational management of our food physics laboratories and food processing facilities, supporting cutting-edge research in protein and food ingredient functionality and processing. The position is designed to provide continuity and leadership within the group’s research infrastructure and to strengthen our capabilities in experimental food process technology. The job As Research Manager, you will be responsible for the daily organisation, coordination, and scientific management of laboratory and pilot-scale activities within food physics and food process technology. Your work will support research focused on the physical chemistry of proteins and food ingredient interactions, and how these are affected by food processing operations. You will be expected to work hands-on in the laboratory and processing facilities, while also taking a proactive role in method development, implementation of new technologies, and optimisation of experimental and processing workflows. The position involves close collaboration with the Head of Research Group, project leaders, researchers, students, and external partners, including industry. A key aspect of the role is to ensure that experimental procedures, analytical methods, and processing trials are conducted to the highest scientific, technical, and safety standards. Our expectations of you Your overall focus will be to ensure high-quality experimental research and efficient operation of food physics laboratories and food processing units within the research group. Your primary responsibilities include: Daily coordination and management of laboratory and pilot-scale food processing activities Hands-on experimental work in food physics laboratories, including chromatographic methods, rheological characterisation, SEM and CLSM imaging and physical chemistry studies of proteins and food ingredient interactions Operation, development, and support of food processing unit operations, such as spray drying technology and related processing equipment Introduction, evaluation, and implementation of new analytical methods, experimental approaches, and processing technologies Development, optimization, and documentation of laboratory and processing protocols Assist with supervision, training, and mentoring of BSc and MSc students, PhD fellows, postdoctoral researchers, visitors, and technical staff in laboratory techniques and processing methods Active participation in ongoing research projects, including collaboration with internal and external (industrial) partners Preparation and presentation of experimental results at project meetings and research forums, including preparation of figures, slides, and technical documentation Contribution to the strategic development and long-term operation of laboratory and pilot-scale research infrastructure within food process technology Qualifications PhD with substantial research experience in food technology. Strong background in food processing and food physics, including protein chemistry and food ingredient interactions Proven hands-on experience with analytical techniques such as chromatography, rheology, physical chemistry-based and microstructure characterization methods Experience with food processing unit operations, preferably pilot scale ultrasonication, spray drying, fermentation, extraction and related technologies Demonstrated ability to develop, implement, and optimize laboratory and processing protocols Experience in supervision, training, and coordination of students and research staff Strong organizational skills and a structured approach to laboratory and research management Excellent communication skills in English (written and spoken) Ability to work independently while fostering collaboration across disciplines and with external partners What we offer in return We offer an interesting and challenging job in an international atmosphere with the focus on research, teaching, innovation and scientific advice for the benefit of the surrounding community. We place emphasis on a high level of professionalism among our staff, so skills development is an integral part of our organization. We offer a great flexibility in the position. In the area of technical and natural sciences, DTU is one of the leading research and education institutions in Europe. Salary and appointment terms The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations (AC). The period of employment is two years The position is a full-time position. Starting date is 1 April 2026 (or according to mutual agreement). The workplace is DTU Lyngby Campus. Application and contact Please submit your online application no later than 12 March 2026 (23:59 Danish time). Open the “Apply now” link, fill out the form and attach your motivated application, CV and exam certificates. If you would like additional information about the position, please contact Associate Professor and Head of Research Group, Mohammadamin Mohammadifar on moamo@food.dtu.dk Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now

PhD scholarship in Next-Gen Microbial Vitamin Biofortification for Plant-Based Applications – part of a MSCA Doctoral Network on micronutrients in sustainable and nutritious diet

About the MSCA project  MICROSUNSET is a Marie Sklodowska-Curie Actions Doctoral Network (MSCA-DN) funded by the European Union in which we have 12 open positions for Doctoral Candidates (DCs). We aim to create a network of early-stage researchers equipped with knowledge and skills – including entrepreneurship – to develop and support implementation strategies that address micronutrient deficiencies in Europe as diets shift toward more plant-based foods. For MICROSUNSET we will recruit 12 highly talented DCs whose collective research will focus on bio-accessibility and bioavailability of micronutrients, and strategies to produce and process plant-based foods with enhanced concentration of micronutrients as an integrative part of sustainable and healthy diets. Development of analytical methods, digestion models, dietary modelling, and conducting consumer surveys will form part of the Doctoral Network’s tasks. The 12 PhD candidates will be based across seven different universities in Europe: four in Denmark (three at the Technical University of Denmark and one at the University of Copenhagen), two in Germany (Technical University of Munich), one in the Netherlands (Wageningen University), one in Ireland (University College Cork), two in the United Kingdom (University of Newcastle upon Tyne), and two in Finland (University of Helsinki). To train the DCs as the next generation of micronutrient researchers in our international and interdisciplinary program, MICROSUNSET brings together experts from several disciplines as supervisors, forming a consortium of seven beneficiaries (see above) and fourteen associated partners including six from industry and two start-ups. More information may be found on MICROSUNSET. To be eligible for a MICROSUNSET PhD-position, you must not have lived, studied, or worked in the host country for more than 12 months in the last 36 months, and must not already hold a doctoral degree. About the PhD-position  Are you interested in becoming part of MICROSUNSET and building a strong foundation for a successful research career? Are you passionate about microbiology and its role in improving the nutritional quality of food? The DTU National Food Institute at the Technical University of Denmark is seeking a highly motivated applicant for a PhD scholarship focused on the use of microbiological approaches to enhance the nutritional value of plant-based foods. You will join the Research Group for Microbial Food Biotechnology, which specializes in applying microbial solutions to improve food quality, functionality, and safety. The results generated in our projects contribute to the development of nutritious and safe diets and support sustainable food innovation. PhD Project The primary objective of the PhD project is to identify, develop, and apply beneficial microorganisms (QPS) capable of enhancing essential vitamins (B2, B12, and K2) in plant-based foods. Key tasks include: Screening microbial candidates from the NFICC collection at DTU Food using in-silico and in-vitro approaches to identify strains with high vitamin-producing potential. Strain improvement using non-GMO methods such as droplet microfluidics and adaptive laboratory evolution (ALE). Development of fermented plant-based products, including oat- and legume-based yogurts, using selected microbial strains. Collaborative research and training, including research stays at Wageningen University (WUR) and Novonesis, providing insight into industrial processes and bridging academic research with practical applications. This project offers a unique opportunity to gain hands-on experience at the interface of microbiology, food technology, and bioengineering, contributing to innovative solutions for the nutritional challenges in plant-based diets. Throughout the project, you will collaborate with other Doctoral Candidates (DCs) in the MICROSUNSET consortium to contribute to generating evidence-based knowledge about micronutrient content, intake, digestibility and bioavailability from plant-based diets. Part of the PhD-study is planned to take place as an external stay at Wageningen University & Research, The Netherlands. Responsibilities and qualifications The primary goal of this PhD project is to identify and develop strains using non-GMO techniques such as droplet microfluidics and adaptive laboratory evolution (ALE) bacteria capable of producing essential vitamins for plant-based diets. As part of your research, you will Enrol in DTU National Food Institute’s doctoral school and comply with its doctoral training requirements Participate actively in the MICROSUNSET training (12 ETCS), dissemination, communication and exploitation activities. Conduct high-quality research under supervision of a diverse scientific team Publish and present research results in international conference proceedings and peer-reviewed scientific journals. Prepare and defend a doctoral thesis in the field of micronutrients and sustainable food products. Support student supervision and contribute to teaching at BSc and MSc levels. You must hold a two-year master’s degree (120 ECTS points) in Food Technology or a similar degree at the equivalent academic level. Furthermore, the ideal candidate has: Completed a relevant master’s program. Strong interest in microbiology, fermentation, and functional foods. Hands-on experience in identification, selection, and non-GMO optimization of bacterial strains. Practical experience with analytical equipment and microfluidics platforms. Strong interest in and understanding of bioinformatics. Good communication skills in English, both written and oral. Experience with international collaboration and the ability to work effectively in interdisciplinary teams. A structured and analytical approach to work and problem-solving. Experience with research dissemination – e.g. scientific publications and/or conference contributions. Other professional and personal qualifications relevant for the PhD project will also be taken into consideration. Approval and Enrolment The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education Assessment Assessment of the candidates will be conducted by an assessment committee which follows the MICROSUNSET recruitment set-up and the Code of Conduct for the Recruitment of Researchers, promoting an inclusive, merit-based, transparent, and unbiased recruitment process. After an eligibility check assessment will be based on the qualification requirements listed above, as well as the grades from MSc/BSc education. A two-step procedure for applicant selection will be undertaken, involving evaluation of the application and at least one interview. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and appointment terms Salary, pension and terms of

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