Position of Research Assistant to characterize antigen-specific B cell receptor repertoires

Do you want to contribute to top quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. Our key words are multidisciplinary, bridging, national and international collaborations. We are now recruiting a research assistant to work in the group of Professor Gunilla Karlsson Hedestam.

Your mission

You will work with both wet and dry lab tasks to characterize antigen-specific B cell receptor repertoires. The work will focus on generating high-throughput sequence data and analyzing the results with a range of specialized analysis pipelines developed in the group. The work will also include the isolation of monoclonal antibodies from single B cells using RT-PCR, cloning and production of recombinant antibodies in mammalian cells and functional analysis of such antibodies as well as antibody engineering.

Your profile

Requirements for the position

• You have recently completed (or will very soon complete) a Master program in Biomedicine or related topic.
• You have robust experience working with multiplex PCR, next generation sequencing and standard molecular biology approaches applied to the analysis of adaptive immune receptor genes.

Meritous

• Experience with immune repertoire sequencing and expression of recombinant proteins in mammalian cells is an advantage.

You are fluent in both written and spoken English, and you are keen to learn different software tools and use basic programming to analyze biological data.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Application

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

This is a temporary position during 12 months