Fixed-term

Postdoctoral researcher – Translational cancer immunology / CAR T-cell therapy

At the Chair of Experimental Medicine and Therapy, we investigate the mechanisms of systemic tumor spread and metastasis ( www.experimentelle-medizin.de ). A project funded by the German Cancer Aid (DKH) has been secured for Dr. Melanie Werner-Klein’s laboratory. Building on a recent publication in Nature Cancer (doi: 10.1038/s43018-025-00963-w), the project focuses on the prevention of metastatic disease – one of the central unsolved problems in oncology. Metastases cause the majority of cancer-related deaths. To date, effective adjuvant strategies for the targeted elimination of disseminated tumor cells are lacking. The position enables independent collaboration on the project for the development of adjuvant CAR-T cell therapies against metastasis-causing cells in melanoma, with a focus on preclinical in vivo models to investigate mechanistic and translational questions with high clinical relevance. We offer: A fully funded postdoctoral position with a duration of three years A dynamic and supportive scientific environment Access to excellent research infrastructure, modern animal facilities and innovative technologies Close scientific supervision, excellent conditions for high-ranking publications, and targeted support for further scientific qualification and academic independence. Your tasks: Independent conception, implementation and scientific management of a postdoctoral research project at the interface of tumor immunology, metastasis biology and CAR-T cell therapy Establishment, optimization and application of preclinical in vivo tumor models Analysis, evaluation and interpretation of complex experimental datasets and their classification in a translational and clinical context Publication of research results in high-ranking international journals Your profile: Completed PhD in tumor immunology, cancer biology, molecular medicine or a closely related field Strong scientific interest in cancer immunotherapy and metastasis biology Proven practical experience with preclinical in vivo cancer models (mandatory) Experience in T-cell biology and/or CAR-T cell development and therapy is an advantage. Independent, structured work style and high self-motivation Excellent written and spoken English skills; knowledge of German is desirable. The University of Regensburg aims to increase the proportion of women on its staff and therefore explicitly encourages qualified women to apply. The University of Regensburg is particularly committed to supporting work-life balance (further information can be found at https://www.uni-regensburg.de/universitaet/jobs-und-karriere/familien-service ). Applicants with severe disabilities will be given preference if they are essentially equally qualified. Please indicate any existing severe disability in your application. Please note that we cannot cover any costs you may incur in connection with a potential job interview. Contact: For further information, please contact Dr. Melanie Werner-Klein (email: melanie.werner-klein@ukr.de / phone: +49 941 944-11223). Applications, including the usual documents, must be submitted by April 15, 2026, exclusively via the application button below . *Note regarding the time limit: The fixed-term employment is for the purpose of the candidate’s own academic qualification (habilitation) and has a contract duration of 3 years. (§ 2 para. 1 WissZeitVG). Apply Now

Technical Assistant Position in Professorship for Immune Cell-Tissue Interactions

Our international team, led by Prof. Dr. Carmen Gerlach, investigates the diversity of T-cell responses to cancer, infections, and inflammatory diseases. Understanding how and when T cells diversify to assume different roles paves the way for influencing T-cell fate in the context of immunotherapy. We are part of the Faculty of Medicine at the University of Regensburg and integrated into the Leibniz Institute for Immunotherapy. Further information about our work can be found here: https://lit.eu/our-scientists/prof-carmen-gerlach/ We offer: An international, highly motivated and cooperative team A state-of-the-art, international research environment with access to cutting-edge equipment Extensive interactions and collaborations with scientists from the Karolinska Institute in Sweden and research groups from the Leibniz Institute for Immunotherapy in Regensburg Flexible working hours, flat hierarchies Your tasks: Planning and organization of the breeding of transgenic mouse lines (colony management, genotyping, phenotyping), coordination with the animal stable staff Support/conduct of experiments with mice (blood sampling, standard injection techniques, experiment termination, tissue sampling, and more), including tumor and infection experiments. Support in the laboratory: e.g. preparation of solutions, aliquoting, management of laboratory chemicals, molecular biological and cellular work including genetic engineering. Organization of research/laboratory setup in connection with the establishment of a new group in Regensburg / relocation to a new building, e.g., coordination and organization with other research groups, equipment procurement, implementation of procedures, establishment of methods. Collaboration with and support of doctoral and postdoc students in their experiments. Training of new group members, including students. Laboratory management, ordering, active contribution to the smooth functioning of the local research environment Your profile: Completed training as a Technical Assistant (m/f/d) – BTA, MTA, CTA, Bachelor’s degree or equivalent High level of commitment, reliability, diligence, team spirit, excellent technical skills, and an interest in science. Ability to work responsibly, independently, and collaboratively. Practical experience working with mice, FELASA certification Ideally, experience with molecular biological methods including genetic engineering and culture of primary cells. Good communication skills in English and ideally also German. Strong interest in fostering an inspiring and supportive group atmosphere The University of Regensburg aims to increase the proportion of women on its staff and therefore explicitly encourages qualified women to apply. The University of Regensburg is particularly committed to supporting work-life balance (further information can be found at https://www.uni-regensburg.de/universitaet/jobs-und-karriere/familien-service ). Applicants with severe disabilities will be given preference if they are essentially equally qualified. Please indicate any existing severe disability in your application. Please note that we cannot cover any costs you may incur in connection with a potential job interview. Contact: For further information, please contact Prof. Carmen Gerlach (email: Carmen.Gerlach@med.uni-regensburg.de ). Applications with the usual documents must be submitted by March 28, 2026, exclusively via the application button below . Note regarding the time limit: Since the appointment is temporary according to § 14 para. 2 of the Part-Time and Fixed-Term Employment Act, applicants who have already been or are currently employed by the Free State of Bavaria cannot be considered. A permanent contract is being sought. Apply Now

PhD Position in project contributes to EuroWorm by concentrating on a targeted, specimen-based investigation of marine annelid diversity and evolutionary relationships

The Johann-Friedrich-Blumenbach Institute of Zoology and Anthropology at the Georg-August-Universität Göttingen is looking to fill the position of a Doctoral / Ph.D. Student (all genders welcome) for research on Unlocking hidden marine annelid diversity through phylogenomics and integrative taxonomy. The position is funded by the Leibniz Collaborative Excellence Program for a period of three years, with a salary according to the German salary scale TV-L E13 (65%), and should be filled by 1st May 2026. This PhD position is part of the EuroWorm project, a collaboration between the Leibniz Institute for Biodiversity Change (LIB), Georg-August-University Göttingen, the Senckenberg Nature Museum, and the Rheinische Friedrich Wilhelm University of Bonn. EuroWorm is a new interdisciplinary initiative that brings together museum-based experts in marine annelids with specialists in genomics and bioinformatics. Its overarching aim is to unlock Europe’s hidden biodiversity by applying state-of-the-art molecular and computational tools. The project seeks to accelerate global biodiversity discovery by making museum collections more accessible through open data and to advance our understanding of annelid evolution across broad spatial, ecological, and temporal scales. PhD Project – Specific Focus The PhD project contributes to EuroWorm by concentrating on a targeted, specimen-based investigation of marine annelid diversity and evolutionary relationships. The work will involve coordinated field sampling at selected type localities across Europe and the generation of high-quality morphological and genomic datasets for these species. These data will be directly linked to digitized voucher specimens housed in major natural history museums, reinforcing their role as essential biodiversity repositories. Using cost-effective genome-skimming, the PhD project aims to produce a densely sampled phylogenetic framework for selected annelid lineages, with particular attention to groups that are rare, symbiotic, or morphologically derived. The phylogenetic framework and integrative taxonomy will be used to explore how key evolutionary transitions, such as changes in body plan, reproductive strategies, regenerative abilities, and symbioses have shaped diversification within annelids. The PhD candidate will collaborate closely on the production and analysis of low-coverage genomic data with a project postdoc based at LIB Hamburg, as well as with a PhD candidate based at the Senckenberg Nature Museum in Frankfurt focused on uncovering the genomic basis of evolutionary novelties in marine annelids, including de novo genome assemblies and comparative genomic analyzes related to evolutionary innovations and biomineralization. Your Tasks • Conduct field sampling at key type localities across Europe. • Generate and analyze morphological and genomic data for selected marine annelid species. • Digitize and link specimen-based data to museum voucher collections. • Build phylogenetic trees using genome-skimming and other molecular datasets. • Contribute to integrative taxonomy of target groups. • Investigate evolutionary transitions within Annelida using comparative approaches. • Collaborate with project partners, including the associated PhD student at Senckenberg Frankfurt. • Present and discuss results in lab meetings, seminars, and scientific conferences. • Contribute to publications in peer-reviewed journals. Your Profile • Diploma or MSc degree in Biology or a closely related field. • Background in molecular systematics or evolutionary biology. • Practical experience in microscopy and molecular as well as morphological laboratory techniques. • Strong motivation to conduct independent, hypothesis-driven research. • Ability to work collaboratively in an interdisciplinary, multinational team. • High proficiency in English; knowledge of German and/or Spanish is beneficial. • Willingness to participate in fieldwork and contribute to group activities, including student mentoring. Desirable Skills • Familiarity with annelids or other lophotrochozoans (advantageous but not required). • Basic skills in next-generation sequencing (NGS) technologies and bioinformatics (eg, sequence assembly, phylogenetics, comparative analyses). • Interest in natural history collections and digitization workflows. • Strong organizational skills and a proactive approach to problem-solving. This position offers an excellent opportunity for early-career researchers to gain comprehensive experience in fieldwork, museum collections, molecular methods, and large-scale comparative analyses, while developing scientific independence within a dynamic and collaborative research environment. The University of Göttingen is an equal opportunities employer and places particular emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply in fields in which they are underrepresented. The university has committed itself to being a family-friendly institution and supports its employees in balancing work and family life. The University is particularly committed to the professional participation of severely disabled employees and therefore welcomes applications from severely disabled people. In the case of qualification equals, applications from people with severe disabilities will be given preference. A disability or equality is to be included in the application in order to protect the interests of the applicant. How to apply? Please send your application (letter of motivation with a short description of your previous and current research foci, a CV, certificates of academic achievements, list of publications as well as letter(s) of recommendation, if available) electronically (as a single PDF) until April 1, 2026 in electronic form to M aria Teresa Aguado ( aguadomolina@uni-goettingen.de ) and Conrad Helm ( chelm@uni-goettingen.de ), Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Animal Evolution and Biodiversity, Georg-August-Universität Göttingen, Untere Karspüle 2, 37073 Göttingen, Germany. For further questions, please contact one of the latter. For further questions regarding the project and the position please contact Maria Teresa Aguado Molina (Email: aguadomolina@uni-goettingen.de ), Conrad Helm (Email: chelm@uni-goettingen.de ), or Christoph Bleidorn (Email: christoph.bleidorn@biologie.uni-goettingen.de ) .  Please note: With submission of your application, you accept the processing of your applicant data in terms of data-protection law. Further information on the legal basis and data usage is provided in the information sheet on the General Data Protection Regulation (GDPR) https://www.uni-goettingen.de/tippdsgvo 

PhD position in Cellular Neurobiology

Constructor University (formerly Jacobs University) is a private, state-accredited, English-language university in Bremen. We offer Bachelor, Master, and PhD programs in three schools: School of Science, School of Computer Science and Engineering, and School of Business, Social and Decision Sciences. Our principles are first-class teaching and research, international diversity, and transdisciplinary cooperation. According to the 2024 Times Higher Education (THE) World University Rankings, Constructor University is among the top 25 percent out of more than 1900 universities worldwide and is ranked as the second most international university in the world. As an international university, we attract highly talented and open-minded students from all over the world. Currently, over 1,600 students from 110 nations live and study on our residential campus. We invite applications from interested candidates for the following position, available immediately: PhD position in Cellular Neurobiology (m/f/d) (full time; 3 years) Our recently established research group develops and studies human-relevant models for neurobiology. We use induced pluripotent stem cells to generate cell-based models of the human brain, so-called brain organoids. These 3D brain models allow us to study neurotoxicity, factors influencing neurodevelopment – such as sex hormones, environmental toxicants, and genetic or developmental disorders – and the mechanisms shaping early brain function. About the PhD project: In this project, you will generate and characterize human brain organoids from male and female donors and analyze their electrophysiological activity using multi-electrode array (MEA) technology. A central goal is to quantify electrophysiological network metrics and connect them to developmental trajectories within the organoids. You will investigate how the factors mentioned above affect early network formation, cellular differentiation, maturation, and functional connectivity in this model system. Your profile: Motivated, reliable scientist with organizational and problem-solving skills Communicative, enthusiastic team player BSc and MSc in Biology, Neuroscience, Biochemistry, Bioinformatics, or related fields Hands-on experience in e.g. Cell Culture, Omics approaches or Molecular Biology Basic programming skills (e.g., Python or R) or motivation to learn Fluency in English is required; German skills are an advantage, primarily for interactions outside the lab What you can expect at Constructor University: We are an international, world-class private university embarking on an exciting journey of growth and expanding our portfolio. Join us and become a part of our global teams! Flexible working hours for work-life balance Individual onboarding, support, and development planning Corporate fitness with EGYM Well Pass (formerly Qualitrain) Green campus with extensive dining options and recreation areas, take the tour: Campus Constructor University has comprehensive sustainability and environmental programs Constructor University unequivocally guarantees the academic freedom of every member of the faculty, as well as every other member of the Constructor University community. We encourage diversity in the University in ethnic, cultural, social, religious, political, and national backgrounds, as well as in individual lifestyle. Constructor University offers full equality of opportunity to all qualified applicants and is an equal opportunity employer. Your application: For any further information regarding this position, please contact Prof. Maren Schenke, via email (mschenke@constructor.university). For your application, please upload a single PDF file (NameSurname.pdf) including: (1) A motivation letter outlining your interest and suitability for the position (2) A curriculum vitae (3) A brief summary of previous research-related experience (max 1 page) (4) Copies of certificates and diplomas (5) Contact details of two academic referees (6) Proof of English proficiency (optional) Applications will be reviewed on a rolling basis until the position is filled. Please note that only applications submitted through the official application portal will be considered. Shortlisted candidates will be invited to online or in-person interviews.

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