Fixed-term
PhD scholarship in Multi-target acute GPCR inhibitors for migraine delivered via intranasal mRNA-encoded binders
If you are motivated by hands-on experimental research and want to help develop the next generation of RNA-based therapeutics, this PhD position offers a unique opportunity to work at the interface of protein engineering, mRNA delivery, and translational neuroscience. At Technical University of Denmark (DTU), you will join an ambitious and collaborative research environment at DTU Bioengineering focused on engineering biological solutions to major health challenges. Responsibilities Your overall focus will be to experimentally develop and validate multi-target GPCR inhibitors using advanced wet lab approaches. The position is primarily laboratory-based, with complementary data analysis and interdisciplinary collaboration. Your primary tasks will be to: Clone, express, and characterize therapeutic minibinders Develop and optimize synthetic mRNA constructs Perform cell-based functional GPCR assays Conduct protein purification and biochemical characterization Evaluate biological activity in relevant in vitro systems Contribute to in vivo validation studies (e.g., electrophysiological readouts) Analyze data and publish results in peer-reviewed journals Qualifications You must: Hold (or are close to completing) an MSc degree in Bioengineering, Biotechnology, Molecular Biology, Biomedicine, or similar Have strong hands-on experience with molecular biology and protein expression Have experience with cell culture and functional assays Demonstrate structured experimental planning and independence Are highly motivated and able to work in an interdisciplinary team Communicate fluently in English (written and spoken) You must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree. Approval and Enrolment The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and appointment terms The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. Starting date will be 1 June 2026, or as soon as possible thereafter. You can read more about career paths at DTU here. Further information Further information may be obtained from Associate Professor Timothy P. Jenkins (tpaje@dtu.dk) You can read more about DTU Bioengineering at www.bioengineering.dtu.dk If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. Application procedure Your complete online application must be submitted no later than 3 April 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: A letter motivating the application (cover letter) Curriculum vitae Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale List of publications You may apply prior to obtaining your master’s degree but cannot begin before having received it. Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now
Research Assistant in Cancer Systems Biology
We are looking for a Research Assistant to work with the Cancer Systems Biology Group at the Section of Bioinformatics at the Department of Health Technology (DTU Health Tech) at DTU, under the supervision of Dr. Elena Papaleo. The project will involve analyses of variants effects at the protein level using a structure-based framework developed by the group. Responsibilities and qualifications The focus will be on proteins related to cancer predisposition or rare disease. Additionally, the candidate will contribute to develop new pipelines and protocol for the framework with focus on modelling the effects of small insertion and deletions. The candidate will also help with data management tasks for the database of variants effect that we are maintaining at DTU. We are looking for a motivated scientist with strong expertise in protein molecular modelling, protein science, biochemistry and programming in Python and usage of SnakeMake. The applicant should also have experience in working on HPC clusters and on Linux/Unix environments. Previous experience with methods as FoldX, Rosetta, Molecular Dynamics Simulations, EVE and analyses of disease-related databases such as ClinVar or COSMIC is recommended. As a formal qualification, you must have a master’s degree in engineering or equivalent. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and terms of employment The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 11 months with starting date 1 June 2026. The position is a full-time position. You can read more about career paths at DTU here. Further information Further information may be obtained from Elena Papaleo, Cancer Systems Biology group. You can read more about DTU Health Tech at www.healthtech.dtu.dk. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure Your complete online application must be submitted no later than 31 March (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) CV Academic Diplomas (MSc) Contacts information of two scientists from previous working place(s) as references Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now
PhD scholarship in Synthetic Metabolism for Extending the Metabolic Landscape of Bacterial Cell Factories
Are you ready to make a difference for a sustainable future through bacterial metabolic engineering? The Systems Environmental Microbiology (SEM) group at DTU (BRIGHT) seeks a candidate for a 3-year, fully-funded PhD project. In this research programme, the PhD student will apply state-of-the-art synthetic biology and genome and metabolic engineering to enable environmental bacteria to synthesize and degrade new-to-Nature metabolites for sustainable and circular production of novel and sustainable materials for the energy sector, one key mission of BRIGHT. Responsibilities The PhD project aims to design, construct, and evolve new metabolic pathways for producing and degrading halogenated metabolites and related compounds in Pseudomonas putida. These engineered strains will serve as sustainable cell factories for the biosynthesis of high-value chemicals, while tackling some of the biggest challenges of our modern societies, i.e. the so-called “forever chemicals” (PFAS). The successful PhD candidate will use a combination of adaptive laboratory evolution and rational metabolic engineering to achieve these goals. In addition, they will develop growth‑coupled selection strategies to discover improved enzyme and pathway variants. The candidate will join an international research team that has pioneered new fluorine chemistries in living cells and is expected to contribute creatively, shape and drive their own project, and engage actively in collaborative efforts. They will disseminate their scientific results at international conferences and through publications in high‑impact journals. Key Selection Criteria Hands-on experience in synthetic biology, particularly of Pseudomonas species. Experience in metabolic engineering, synthetic biology and genome-scale metabolic modeling. Knowledge of protein purification and mining is highly desirable. Experience in reporting and self-organizing skills. Enthusiastic and self-driven, independent thinking and strong social skills. Team player capabilities. Excellent written and oral communication skills in English. You must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree. Approval and Enrolment The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and appointment terms The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. Starting date is the 1st of June 2026 or according to mutual agreement. You can read more about career paths at DTU here. Further information Further information may be obtained from Prof. Pablo I. Nikel (pabnik@dtu.dk) You can read more about BRIGHT here If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. Application procedure Your complete online application must be submitted no later than 6 April 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: A letter motivating the application (cover letter) Curriculum vitae Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale Two references that can be contacted to support your application. You may apply prior to obtaining your master’s degree but cannot begin before having received it. Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now
Senior Researcher in interactions between fisheries, anthropogenic pressures, and endangered, threatened and protected species (ETPS)
As Senior Researcher, you will join our Section for Ecosystem Based Marine Management in Lyngby, where 35 employees work to advance interdisciplinary research and improve our knowledge of marine ecosystems and their management. The section offers colleagues with a variety of backgrounds and personalities working together in an internationally recognized and highly dynamic scientific environment. Responsibilities and qualifications Your employment will strengthen the department’s competences within interactions between fisheries and marine mammals including bycatch, competition for forage fish stocks, disturbances from vessels, gear entanglement, and noise. You will work with our excellent team consisting of academic colleagues and public and industrial partners in Denmark and internationally. Your primary tasks will be to: Advance research on interactions between fisheries, marine mammals, and other anthropogenic pressures and present the achievements in peer-reviewed publications, strategic assessments and international conferences and expert meetings. Lead and contribute to the preparation of national and international grant proposals. Contribute to teaching and supervision of PhD, Bachelor and Master students Establish and strengthen collaborations with universities, national and international government agencies, fisheries sectors, NGOs, and international research and advice networks. Innovate monitoring approaches, analytical methods, and modelling frameworks related to marine mammal ecology and human impacts. You must contribute to teaching at the Department. DTU employs two working languages: Danish and English. You are expected to be fluent in at least one of these languages, and in time are expected to master both. As a formal qualification you must hold a PhD degree (or equivalent) as well as academic qualifications equivalent to those obtained by holding a position as a researcher or postdoc. To be appointed as a senior researcher, you must have completed a didactic/pedagogic education. If you do not have the necessary education, then it is possible to complete this requirement within a period of two years of appointment. Specific qualifications include: Strong skills in acoustic data acoustic data analysis and other types of quantitative and statistical data analyses and programming In depth knowledge of marine mammal behavioral ecology in the North Atlantic and Arctic, experience with marine field work and estimation of fisheries interactions and bycatch Experience with stakeholder contact and involvement Excellent collaboration and communication skills You will be assessed against the responsibilities and qualifications stated above and the following general criteria: Research experience Experience and quality of teaching Research vision and potential International impact and experience Societal impact Innovativeness, including commercialization and collaboration with industry Leadership, collaboration, and interdisciplinary skills Communication skills Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. You can read more about career paths at DTU here. Starting date is 1st of August 2026. The position is a full-time position. Further information Further information may be obtained from Lotte Kindt-Larsen at loki@aqua.dtu.dk, or tel.: +45 35 88 33 94. You can read more about “the Department” at aqua.dtu.dk/english/about/organization/scientific-sections/section-for-ecosystem-based-marine-management If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure Please submit your online application no later than 7 April 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) Vision for teaching and research CV including employment history, list of publications indicating scientific highlights, H-index and ORCID (see http://orcid.org/) Teaching portfolio including documentation of teaching experience Academic Diplomas (MSc/PhD) You can learn more about the recruitment process here. Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now