Fixed-term

Doctoral scholarship holder “Development of a Zebrafish Model of SMAD3-Dependent Thoracic Aortic Aneurysm for In Vivo Drug Screening”

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Let’s shape the future – University of Antwerp The University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20000 students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international and most innovative employers in the region. With more than 6000 employees from 100 different countries, we are helping to build tomorrow’s world every day. Through top scientific research, we push back boundaries and set a course for the future – a future that you can help to shape. In a joint effort with the Center for Medical Genetics Ghent (CMGG; this will be the secondary host institution in a joint PhD program), the Center of Medical Genetics (CMG; primary host institution) in the Faculty of Medicine and Health Sciences of the University of Antwerp is looking for a full-time (100%) doctoral scholarship holder in the field of “Development of a Zebrafish Model of SMAD3-Dependent Thoracic Aortic Aneurysm for In Vivo Drug Screening”. Join us in tackling a silent killer Thoracic aortic aneurysm (TAA) develops and progresses silently until life-threatening dissections and/or ruptures occur. No curative treatment currently exists. Among its genetic causes, Loeys-Dietz syndrome type 3 (driven by pathogenic variants in SMAD3), represents one of the most severe forms of the disease. In this PhD project, you will contribute to preclinical SMAD3-related TAA research by: 🐟 Developing a smad3 knockout zebrafish model, 🔬 Optimizing in vivo visualization of aortic enlargement and molecular dysfunction, 💊 Developing a pathogenic signalling-based drug screening assay. The project will be largely executed at the Antwerp CMG, embedded within the University of Antwerp and the Antwerp University Hospital. It has gained substantial know-how and hosts state-of-the-art infrastructure in the field of clinical, molecular and pathophysiological investigation of hereditary diseases, including heart and large vessel diseases, hearing loss, cancer, bone diseases and intellectual disability. Within this environment, the research teams of Prof. Verstraeten and Prof. Loeys spearhead the projects focused on cardiovascular and connective tissue disorders. The project will be co‑supervised by Prof. Sips from the CMGG at the Department of Biomolecular Medicine of Ghent University, where part of the work will be carried out. Prof. Sips has a strong expertise in zebrafish models of genetic cardiovascular disease and co‑leads the Ghent Heritable Thoracic Aortic Disease laboratory. Position You will work actively on the preparation of a PhD thesis in the field of preclinical TAA research, publishing high-quality scientific articles related to the research project. You will present your work at national and international scientific workshops and conferences. Profile You hold a master’s degree in (Bio)medical sciences, Biochemistry and/or Biotechnology, Biomedical Engineering or you will have obtained it by the time you start to work. You are eligible for applying for a Research Foundation Flanders (FWO) PhD fellowship Your research qualities are in line with the faculty and university research policies. You can demonstrate excellent study results. You bring ambition, integrity, and a strong eye for quality, along with a positive mindset. You are a strong team player with good communication skills. You are fluent in written and spoken English. Project-specific required skills You successfully acquired a FELASA B or FELASA C certificate. Project-specific desirable skills You have expertise in zebrafish work. You have experience in the field of cardiovascular diseases. You have expertise in cutting-edge microscopy. What we offer We offer a doctoral scholarship for one year. Following a positive evaluation and pending available funding, the scholarship will be extended for an additional three years. The planned start date is 15/09/2026 or as soon as possible after that date. Your monthly scholarship amount is calculated according to the scholarship amounts for doctoral scholarship holders. You receive ecocheques and a bicycle allowance or reimbursement of public transport costs. As a doctoral researcher, you will have access to a wide and varied range of courses and an educational credit through the Antwerp and UGhent Doctoral Schools. You will do most of your work at CMG Antwerp in a dynamic and stimulating environment. Find out more about working at the University of Antwerp here. Want to apply? You can apply for this vacancy through the University of Antwerp’s online job application platform up to and including 23 April 2026. Click on the ‘Apply’ button and complete the online application form. Be sure to include the following attachments: a motivation letter your academic CV (including honours, grades, skills, prior mobility, publications,…) The selection committee reviews all applications as soon as possible after the application deadline. As soon as a decision is made, we will notify you. If you are still eligible after the pre-selection, you will be informed about the possible next step(s) in the selection procedure. If you have any questions about the online application form, please check https://www.uantwerpen.be/en/jobs/apply-online-uantwerp/ or send an email to jobs@uantwerpen.be. If you have any questions about the job itself, please contact Prof. Aline Verstraeten (aline.verstraeten@uantwerpen.be). The University of Antwerp received the European Commission’s HR Excellence in Research Award for its HR policy. We are a sustainable, family-friendly organisation which invests in its employees’ growth. We encourage diversity and attach great importance to an inclusive working environment and equal opportunities, regardless of gender identity, disability, race, ethnicity, religion or belief, sexual orientation or age. We encourage people from diverse backgrounds and with diverse characteristics to apply. Apply Now

Position of Doctoral Fellow in the Department of Biochemistry and Microbiology

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ABOUT GHENT UNIVERSITY Ghent University is a world of its own. Employing more than 15.000 people, it is actively involved in education and research, management and administration, as well as technical and social service provision on a daily basis. It is one of the largest, most exciting employers in the area and offers great career opportunities. With its 11 faculties and more than 85 departments offering state-of-the-art study programmes grounded in research in a wide range of academic fields, Ghent University is a logical choice for its staff and students. YOUR TASKS You will join a research program investigating the molecular mechanisms by which bacterial pathogens deploy type III secretion system (T3SS) effector proteins to manipulate host cells. In particular, this doctoral project will focus on the role of bacterial effector chaperones in regulating effector stability, secretion, and functional targeting during infection. The goal of this research is to systematically dissect chaperone–effector interaction networks in enteropathogens using genetic and proteomics-based approaches. You will generate and characterize bacterial strains carrying targeted deletions of T3SS effector chaperones. You will investigate the impact of chaperone loss on effector expression, stability, and secretion using molecular microbiology and biochemical approaches. You will apply quantitative proteomics and interaction mapping approaches to identify chaperone-associated protein networks. You will integrate genetic, biochemical, and proteomics data to understand how effector chaperones coordinate the bacterial virulence program. You will contribute to the analysis and interpretation of large-scale proteomics datasets. You will present your work at scientific meetings and contribute to peer-reviewed publications. You will participate in the supervision of BSc and MSc students and contribute to the collaborative research environment of the laboratory. You will enroll in the Ghent University doctoral training programme and work towards obtaining a doctoral degree. WHAT WE ARE LOOKING FOR You have a strong interest in molecular microbiology, bacterial pathogenesis, or host–pathogen interactions. Experience with molecular biology, bacterial genetics, microbiological techniques, or protein biochemistry is considered an asset. Interest in proteomics, systems biology, or interaction proteomics is an advantage. You are highly motivated, curious, and eager to develop new experimental and analytical skills. You are able to work both independently and collaboratively within an interdisciplinary research environment. You possess strong analytical and problem-solving skills. You have good communication skills in English (spoken and written). WHAT WE CAN OFFER YOU We offer a full-time position as a doctoral fellow, consisting of an initial period of 12 months, which – after a positive evaluation – will be extended to a total maximum of 48 months. Your contract will start on 01/09/2026 at the earliest. The fellowship amount is 100% of the net salary of an AAP member in equal family circumstances. The individual fellowship amount is determined by Team Personnel Administration based on family status and seniority. A grant that meets the conditions and criteria of the regulations for doctoral fellowships is considered free of personal income tax. Click here for more information about our salary scales  All Ghent University staff members enjoy a number of benefits, such as a wide range of training and education opportunities, 36 days of holiday leave (on an annual basis for a full-time job) supplemented by annual fixed bridge days, bicycle allowance and eco vouchers. Click here for a complete overview of all the staff benefits. INTERESTED? Send your cv, copy of your diploma (if already in your possession) and a motivation letter to petra.vandamme@UGent.be. We do not accept late applications. As Ghent University maintains an equal opportunities and diversity policy, everyone is encouraged to apply for this position. For more information about this vacancy, please contact prof. Petra Van Damme (petra.vandamme@UGent.be, +32 (0)9/264 51 29).

PhD position in Biochemical research in Parkinson’s Disease

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The Laboratory of Cellular Transport Systems (https://www.labcelltransport.com/), led by Prof. Peter Vangheluwe, and the Laboratory of Chemical Biology (https://www.verhelstlab.net/), led by Prof. Steven Verhelst, part of the Department of Cellular and Molecular Medicine, invites applications for a PhD candidate position. The candidate will conduct a joint PhD project investigating Parkinson’s disease under the supervision of Prof. Peter Vangheluwe and Prof. Steven Verhelst. Project Parkinson’s disease (PD) is the second most common and fastest-growing neurodegenerative disease. Unfortunately, there is no treatment to halt or reverse disease progression. Loss-of-function of the lysosomal polyamine exporter ATP13A2 is causative for aggressive early and juvenile onset parkinsonisms, whereas impaired polyamine homeostasis has been reported in sporadic PD. Hence, activation of ATP13A2 has emerged as a prioritized therapeutic strategy for PD, but the regulation of ATP13A2 in lysosomes remains unclear. This project will explore the mechanism by which ATP13A2 is regulated by co-factors such as lipids and proteins i) in vitro on purified ATP13A2 protein and ii) in cells with modulated expression of ATP13A2. Insights into the regulatory mechanisms of ATP13A2 will connect ATP13A2 to other lysosomal pathways implicated in PD, and offer novel therapeutic strategies for ATP13A2 modulation. The lab is actively involved in drug discovery research in collaboration with biotech and the M.J.Fox Foundation.Experimental techniques include: Protein production, purification and reconstitution Targeted mutagenesis and protein structure analysis Biochemical characterization of ATPase and phosphorylation activity Cellular imaging/staining (fluorescence and electron microscopy) Flow cytometry Mammalian cell culture (cell models, including iPSC-derived cell lines) Lysosomal immunoprecipitation for multi-omics analysis Chemical synthesis Integration of biochemical, cellular and chemical biology approaches Profile Master’s degree in “Biophysics, Biochemistry and Biotechnology”, with a specialization in “Biochemistry, Molecular and Structural Biology” Experience in: –       Membrane protein production, purification and reconstitution in proteoliposomes –       Mammalian cell culture (cell models, including iPSC-derived cell lines) –       Biochemical analysis using functional assays like ATPase and phosphorylation quantification –       Biophysical analysis of purified and reconstituted membrane proteins in artificial membrane environments –       Targeted mutagenesis and protein structure analysis in PyMOL/Discovery studio Enthusiastic team player, correct and organised, strong problem-solving skills and proactive mindset Proficiency in English, both spoken and written Offer A stimulating, internationally renowned research environment The opportunity to contribute to high-end research on Parkinson’s disease A close collaboration with international research consortia and funding agencies, generating extra opportunities for future career development Access to training and expertise for laboratory techniques Interested? For further information, if interested, please contact lab manager Marleen Schuermans: marleen.schuermans@kuleuven.be  (+32 16 33 02 13). You can apply for this job no later than April 13, 2026 via the online application tool KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address. Job application procedure Working conditions Career opportunities Do you have a question about the online application system? Please consult our FAQ or email us at apply@kuleuven.be

PhD position in Research on congenital left sided heart lesions: Impact Of Multi

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The PhD project is situated in the Department of Cardiovascular Sciences in collaboration with Human Genetics at KU Leuven. It is part of a European, interdisciplinary project in Pediatric Cardiology, Human Genetics, Gynecology and Neonatology, creating a supportive research environment for fundamental and translational studies of congenital heart diseases. Research will bridge genetic analysis in mother-child pairs, cardiac morphology and postnatal clinical presentation in children with left sided heart disease. Project This PhD position focusses on the wide spectrum of left sided heart lesions in children. They encompass conditions ranging from severe forms like hypoplastic left heart syndrome and aortic stenosis to milder forms of coarctation of the aorta. Despite advancements in surgical interventions, potential impairment of the systemic circulation and oxygen delivery can adversely affect long-term cardiovascular and neurological outcome. This research combines genetic analysis with clinical outcome parameters to  develop a screening and risk stratification model in left sided heart lesions. You will be part of a project that aims to integrate multi-omics technologies, clinical cardiac and neurological investigations, and machine learning to enhance early diagnosis and risk stratification in children with left sided heart disease. Both, genetic and clinical data will allow us to develop targeted diagnostic tools and personalized treatment approaches. In this context, you will coordinate the inclusion of patients, ensure the performance of all investigations and analyze clinical data. You will apply and analyze cardiac imaging, neuro monitoring and laboratory parameters. This approach provides an innovative and detailed clinical assessment and will significantly improve our understanding of the spectrum of congenital left sided heart diseases. Throughout the project, you will closely collaborate with the multidisciplinary team in pediatric cardiology, human genetics, gynecology, neonatology and intensive care medicine. Profile You are requested to have a master’s degree in medicine, biomedical science, neuroscience or bioengineering. Experience in cardiac hemodynamics, neuromonitoring and/or neurovascular coupling is a valuable asset for this PhD position. You have a creative and analytical mindset and an interest in coordinating tasks. You have an interest in cardiovascular research, particularly in congenital heart defects. You have excellent oral and written communication skills in English and preferable also in Dutch. You are expected to work both independently and as part of a team. You are be flexible, precise, and motivated to work in a multidisciplinary research team. You are expected to coordinate the clinical study and work with patient data. You are expected to communicate with the international consortium. You are expected to participate in grant writing and funding acquisition. Offer A supportive and collaborative team in which you can develop know-how and expertise in clinical research aspects of congenital heart disease. Access to clinical treatment and basic research facilities. Integration in the European research landscape. Opportunities to build up research and innovation skills. Possibilities to attend international conferences and networking. Funding is secured for 3 years, intended to be prolonged to 4 years. Interested? For more information please contact Prof. dr. Ruth Heying, mail: ruth.heying@uzleuven.be or Prof. dr. Jeroen Breckpot, mail: jeroen.breckpot@uzleuven.be. You can apply for this job no later than April 30, 2026 via the online application tool KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address. Sollicitatieprocedure Arbeidsvoorwaarden Loopbaanmogelijkheden Heb je een vraag over de online sollicitatieprocedure? Raadpleeg onze veelgestelde vragen of stuur een e-mail naar solliciteren@kuleuven.be

PhD position on plant-wearable sensors and machine learning for crop monitoring in horticulture

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At the Department of Biosystems of the University of Leuven (Belgium), the lab of Prof. Bram Van de Poel conducts research on molecular plant hormone physiology and plant sensing technologies. The lab develops innovative tools, such as digital plant sensors, to monitor plant responses to environmental stress conditions in real time. We have an open full-time PhD position focused on the development of machine learning models for our patented plant-wearable sensors, to enable monitoring and prediction of plant stress for greenhouse crops. Website van de eenheid Project Greenhouse horticulture is increasingly moving toward data-driven crop management systems that allow growers to monitor crop status and optimize production in real time. While most current systems rely on environmental measurements such as temperature, humidity, and light, plants themselves generate physiological signals that directly reflect their stress status and growth dynamics. The Van de Poel lab has developed a non-invasive wireless plant-wearable motion sensor that measures subtle leaf and stem movements (patented). Previous research has shown that plant movement patterns change in response to abiotic stress before visible symptoms arrive, suggesting that these sensor signals may provide early indicators of plant stress and crop status. In this PhD project, you will generate and analyze large datasets of plant movement dynamics collected from greenhouse crops and develop computational methods to extract meaningful physiological signals from these data, to use the sensor for stress and growth prediction. Therefore, you will install networks of plant-wearable sensors within crop canopies in commercial and experimental greenhouse facilities, to generate high-resolution time-series data describing plant movement under different environmental conditions and stress factors. A central focus of the project will be the development of signal processing, time-series analysis, and machine learning approaches (e.g. Efficiently Supervised Generative Adversarial Network) to detect patterns in plant movement and relate them to plant stress and crop status. The long-term ambition is to develop a reliable non-invasive plant-wearable sensing system that enables early detection of plant stress, and supports more autonomous crop monitoring and decision-making in greenhouse horticulture. This PhD project will train you to become a scientist who is ready for future challenges. This means that you will be conducting cutting-edge research under the close supervision of Prof Van de Poel, collaborate with your colleagues (within and outside the lab) and participate in the daily activities of the lab. You are encouraged to guide master’s thesis students, participate at national and international conferences and disseminate your research results in scientific publications. You will also contribute to a larger applied research project conducted in collaboration with experimental research stations and industry partners in the Flemish and Dutch greenhouse horticulture sector (Interreg project). Profile Our team is looking for a PhD candidate with a strong interest in plant production, horticultural management and data modelling. You are a team-player with a critical mind, work accurately and independently and are willing to learn new techniques. Experience with plant physiology, greenhouse management, sensor systems, programming, or machine learning is considered an advantage. Experience with programming and data modelling is particularly valued. You are required to have a European master’s degree (or equivalent) in Bioscience Engineering, Plant Biology, Biotechnology, Agricultural Engineering, Bioengineering, Electrical Engineering, Computer Science, Artificial Intelligence, Data Science, or a related discipline. Offer We offer you a full-time PhD position for 4 years, pending a positive evaluation by your PhD committee after year 1. Remuneration will be according to the KU Leuven salary scales (https://www.kuleuven.be/personeel/jobsite/en/phd/phd-information#working-conditions) and includes generous benefits in addition to Belgium’s strong social and health-care supports. Our young and dynamic team of >15 members, will support you to successfully obtain a PhD degree via an in-depth scientific training at a top-ranked university. You will be closely mentored by Prof. Van de Poel and Dr. Reher as well as a close-knit, international, and diverse community of plant scientists within the Division of Crop Biotechnics. i Interested? For more information please contact Prof. dr. Bram Van de Poel, mail: bram.vandepoel@kuleuven.be or Dr. Thomas Reher, mail: thomas.reher@kuleuven.be. You can apply for this job no later than April 30, 2026 via the online application tool KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address. Sollicitatieprocedure Arbeidsvoorwaarden Loopbaanmogelijkheden Heb je een vraag over de online sollicitatieprocedure? Raadpleeg onze veelgestelde vragen of stuur een e-mail naar solliciteren@kuleuven.be

Position of Postdoctoral Research Fellow (Bioinformatics)

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We are looking for a Postdoctoral Research Fellow specializing in bioinformatics to join The Genomic Regulation for Precision Cancer Medicine Lab at the Faculty of Medicine and Health Technology. The position is full-time and will be filled for a fixed-term period of two years. The Genomic Regulation for Precision Cancer Medicine Lab is led by Alfonso Urbanucci. The research group focuses on Genomic Regulation for Precision Cancer Medicine with particular emphasis on prostate cancer, and it is part of the Prostate Cancer Research Centre (PCRC). The Faculty of Medicine and Health Technology (MET) is committed to high quality research and education in the fields of biomedical engineering, biotechnology, medicine, and health technology. We conduct basic, applied, clinical, and translational research in collaboration with Tampere University Hospital (TAYS). Our existing research areas in health research include biomedical engineering fields from biomaterials and microtechnologies to health data science, cell and molecular biology, with applications in areas such as cancer, cardiovascular and celiac diseases, immunology, and ophthalmology. Job description We are looking for an ambitious and highly motivated postdoctoral researcher to join our research group. The selected candidate will contribute to two projects: Investigation of genetic predisposition to medications-induced side effects In this project knowledge of FinnGen study large-scale genomics is considered an advantage Understanding metastatic potential and tumor immunobiology at the single cell and spatial level In this project  we use all-things-omics, with short and long read sequencing, with emphasis on TCRs and BCRs profiling and predictive models for patients stratification. Requirements The ideal candidate should meet the following criteria: Applicable doctoral degree in Computational Biology, Bioinformatics, or a related field, Understanding of statistics, genetics, immunology, cancer development with emphasis on transcriptomics, Demonstrated ability to work with high-throughput sequencing data and to integrate multi-omics data to study cancer development and progression (work experience with the analysis of genomics data such as spatial and single cell, methylation, ATAC-seq etc. TCR and BCR analysis and in silico data generation is an advantage). Strong understanding of gene transcription regulation and cis-regulatory elements in a cancer setting. Track record of developing reproducible computational pipelines, preferably with workflow management systems like Snakemake, Ability to containerize applications using Docker, Singularity, Apptainer for better software management and reproducibility, Knowledge of deep-learning methods, At least one first author manuscript in the context of omics data analysis in an international peer-reviewed journal in good track for publication (to be demonstrated) or in press at the time of application, Ability to collaborate with researchers from different fields and at different career stages, Willingness to be part of a team to share knowledge and skills, Documented ability to communicate science, Excellent written and verbal communication skills in English, Experience in teaching bioinformatics or a related field at the university level is considered an advantage. Tampere University is a unique, multidisciplinary, and boldly forward-looking community. Our values are openness, diversity, responsibility, courage, critical thinking, and learner-centredness. We hope that you can embrace these values and promote them in your work. We offer The position will be filled for a fixed-term period of two years. The estimated starting date is 2 May 2026, or as mutually agreed upon both parties. A trial period of six months applies to all our new employees. The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). We offer stimulating research projects that will have an impact on the scientific community in a role within an ambitious and multi-disciplinary team that combines the strenghts of both experimental and computational sciences, aimed at delivering high-impact research. In addition, we offer a world-class research environment in internationally recognized research groups. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting. We offer you the opportunity to join our dynamic and innovative international community. As a member of staff at Tampere University, you will enjoy a range of competitive benefits, such as occupational health care services, flexible work schedule, versatile research infrastructure, modern teaching facilities and a safe and inviting campus area as well as a personal fund to spend on sports and cultural activities in your free time. Please read more about working at Tampere University. You can also find more information about us and working and living Tampere by watching our video: Tampere Higher Education Community – our academic playground. Finland is among the most stable, free and safe countries in the world, based on prominent ratings by various agencies. Tampere is the largest inland city of Finland, and the city is counted among the major academic hubs in the Nordic countries. Tampere region is the most rapidly growing urban area in Finland and home to a vibrant knowledge-intensive entrepreneurial community. The city is an industrial powerhouse that enjoys a rich cultural scene and a reputation as a centre of Finland’s information society. Tampere is also surrounded by vivid nature with forests and lakes, providing countless opportunities for easy-to-access outdoor adventures and refreshment throughout the year. Read more about Finland and Tampere:   Visit Finland   This is Finland   Ministry of Economic Affairs and Employment: Welcome to Finland   Visit Tampere How to apply Please submit your application through our online recruitment system. The closing date for applications is 9 April 2026 (23:59 EEST / UTC +3). Please write your application and all accompanying documents in English and attach them in PDF format. Applications should include the following documents: Curriculum Vitae according to TENK guidelines List of publications according to Research Council of Finland guideline Cover letter outlining motivations, career goals, and research interests (1 page max) Names and contact details of at least two referees For more information, please contact: Professor Alfonso Urbanucci, alfonso.urbanucci@tuni.fi With questions related to the recruitment process, please contact: HR Specialist Lilli Sarasvirta, lilli.sarasvirta@tuni.fi

Position of Postdoctoral Research Fellow at the Department of Medical Biology

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The position Do you hold a PhD in molecular biology (or a related field) and have a strong interest in the molecular mechanisms underlying antibiotic resistance development? Are you motivated to conduct interdisciplinary research at one of the northernmost universities in the world? If so, this postdoctoral position may be of interest to you. The Postdoctoral Research Fellow position is available at the Department of Medical Biology, Faculty of Health Sciences, within the Host–Microbe Interaction (HMI) research group. The position is part of the LacZymes, led by Dr. Christopher Frøhlich, and entitled “Epistasis and Evolution of β-Lactamase-Mediated Antimicrobial Resistance.” The position is a fixed term position for a duration of 3 years.  As a Postdoctoral Research Fellow, you will have the opportunity to advance your scientific career and further qualify for academic positions. If you do not already have the educational competence that meets the requirements for an Associate Professor position in Norway, UiT will arrange such competence during the employment period. The workplace is at UiT in Tromsø. You must be able to start in the position within a reasonable time after receiving the offer. If you receive a personal overseas research grant from NFR it is possible to apply NFR for an extension of the fellowship period corresponding to the length of the stay abroad (minimum three months, maximum 12 months). Unless special circumstances indicate otherwise, postdoctoral projects shall be planned with stays abroad. The duration should be at least 6 months. The position’s field of work The successful candidate will join a newly funded Research Council of Norway (FUTURE-AMR) project and work closely with researchers and students to uncover molecular mechanisms of epistasis arising during the evolution of β-lactamases. To address these questions, the project integrates ancestral sequence reconstruction, directed evolution, pre-steady-state and steady-state enzyme kinetics, and X-ray crystallography. Candidates with experience in two or more of these areas are encouraged to apply. The postdoctoral fellow will report to Dr. Christopher Frøhlich and is expected to actively contribute to advancing the field while developing expertise at the interface of molecular biology, enzymology, and evolutionary microbiology. Duties of the position The postdoctoral fellow will work on the following tasks: • Manage your research project • Experimental design and execution • Perform directed evolution and selection • Enzyme production and purification • Biochemical enzyme characterization • Write scientific papers • Presenting your work in national and international arenas Contact For further information about the position, please contact Dr. Christopher Frøhlich: phone:  + 47 46968778 email: christopher.frohlich@uit.no Qualifications Required qualifications PhD in molecular biology, microbiology, biochemistry, or a related field. Candidates who have not yet defended their PhD must submit parts of your dissertation along with the application, and provide documentation from their supervisor confirming that the defense will be completed before the start of the position. Experience in at least two of the following areas: directed evolution, protein expression and purification, biochemical characterization of enzymes, X-ray crystallography. Documented oral and written English skills. Preferred qualifications Experience in the field of AMR and AMR mechanisms Hands-on experience in next generation sequencing and data analysis Knowledge of a Scandinavian language Experience in writing publications Experience in a biosafety level-2 lab environment Personal characteristics The applicant should be motivated, creative and ambitious, with a strong ability to work problem-solution orientated both in teams and independently. The applicant should be genuinely interested in the field of molecular evolution and AMR as well as scientific dissemination. In the evaluation of which applicant is best qualified, emphasis will be placed on education, experience, and personal suitability, in terms of the qualification requirements specified in this position announcement. Emphasis shall also be attached to experience from popularization/dissemination and academic policy and administrative activity. At UiT we put emphasis on the quality, relevance and significance of the research work and not on where the work is published, in accordance with the principles of The San Francisco Declaration on Research Assessment (DORA). No person may hold more than one fixed term position as a Postdoctoral Research Fellow at the same institution. Inclusion and diversity UiT The Arctic University i Norway is working actively to promote equality, gender balance and diversity among employees and students, and to create an inclusive and safe working environment. We believe that inclusion and diversity is a strength, and we want employees with different competencies, professional experience, life experience and perspectives. If you have a disability, a gap in your CV or immigrant background, we encourage you to tick the box for this in your application. If there are qualified applicants, we invite least one in each group for an interview. If you get the job, we will adapt the working conditions if you need it. Apart from selecting the right candidates, we will only use the information for anonymous statistics. We offer A highly international, ambitious and friendly work environment A unique opportunity to get experience in a wide range of interesting research topics. Flexible working hours and a state collective pay agreement Pension scheme through the state pension fund Norwegian health policy aims to ensure that everyone, irrespective of their personal finances and where they live, has access to good health and care services of equal standard. As an employee you will become member of the National Insurance Scheme which also include health care services. More practical information for working and living in Norway can be found here: https://uit.no/staffmobility Application Please note that the application will only be assessed based on the information submitted by the application deadline via Jobbnorge. It is therefore important that you include all necessary documents demonstrating your qualifications for the position. Your application must include: Application letter CV Diplomas and transcripts (all degrees) Documentation of English proficiency. If English proficiency is not documented in the application, it must be documented before starting in the position. Contact information to 2-3 references Documentation of educational competence, if available Description of your academic production, stating which works you consider most important Academic works, up to ten. The doctoral thesis is regarded as one work. If you’re in the final stages of your PhD,

Postdoctoral in Robotics-assisted Strain Characterization – Advancing Sustainable Agriculture

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Are you ready to shape the future of sustainable agriculture? Join DTU Bioengineering as a postdoctoral researcher in the Initiative for Biofertilizer Innovation and Science (IBIS) and contribute to building a world-class research hub focused on advancing microbial solutions for a sustainable future. DTU Bioengineering is excited to announce a 3½ year postdoctoral researcher position, as part of the newly launched global initiative for Biofertilizer Innovation and Science. IBIS is a bold, five-year open-science initiative with the ambition to revolutionize whole-cell biosolutions in agriculture (BioAg). Our goal is to advance the fundamental understanding of what makes an effective biofertilizer and to develop the enabling technologies and translational framework needed to bring robust and affordable microbial solutions to farmers across the globe. The initiative is supported by 210 million DKK (approximately 30 million USD) in combined funding from the Gates Foundation and the Novo Nordisk Foundation. Central to the initiative is the development of an open R&D playbook—freely accessible to researchers worldwide—to accelerate the discovery, maturation, and deployment of scientifically validated microbial biofertilizers. DTU is coordinating the newly established IBIS consortium, which brings together leading partners from across Europe, South Asia, and Sub-Saharan Africa. Each partner contributes unique expertise and experimental capacity spanning the entire biofertilizer R&D pipeline—from laboratory research to field implementation. Together, the consortium will build a comprehensive Biosolutions Development Pipeline for microbial biofertilizers (whole-cell biosolutions), covering all key stages: discovery, characterization, fermentation, formulation, in planta performance, and in-field evaluation. DTU will host the laboratory phase of the pipeline, harnessing advanced robotic workflows and high-throughput screening technologies. Field trials and upscaling activities will be carried out through partner institutions across both the Global South and North, ensuring real-world testing across diverse agricultural contexts. Beyond the research itself, IBIS aims to implement standardized experimental protocols, harmonized data formats, and transparent documentation practices—laying the foundation for reproducible and collaborative research in biofertilizer innovation. The IBIS development pipeline is designed to enable high-throughput benchmarking and advancement of new whole-cell–based biosolutions, supporting their journey from discovery to market launch. The IBIS consortium will use the pipeline to systematically evaluate hundreds of microbial biofertilizer strains, generating large-scale datasets across all stages—from laboratory experiments (thousands of strains) to in-field testing. The scale and standardized approach will create a unique foundation for advanced data analysis, including AI, machine learning, and statistical modelling, aimed at uncovering the key traits that define successful microbial biofertilizers, and to develop predictive models that can guide the rational design of next-generation BioAg products tailored for diverse agricultural systems around the world. This postdoctoral researcher position offers a unique opportunity to join a dedicated, international team of scientists working within the IBIS initiative at DTU and its partner institutions worldwide. You will work collaboratively to address foundational biological questions about the biology of microbial biofertilizers, enabling the efficient engineering and development of solutions. Your contributions will include developing and implementing new robotics-assisted high throughput assay to screen for and characterize microbial biosolutions as an essential part of the Biosolutions Development Pipeline. You will further use the data generated to help us identify and characterize the functional traits that are key for the manufacturability and in field performance of microbial biofertilizer. Your responsibilities: Experience designing automated workflows that generate structured, traceable experimental datasets, with strong attention to data quality and reproducibility Design, develop, and implement new robotic-based phenotypic assays to characterize microbial strain capabilities, robustness, and performance-relevant traits. Strong understanding of microbial physiology and phenotypic traits relevant to strain performance Run and optimize phenotypic screening and characterization workflows to generate large standardized data sets. Focus of scientific work: Identify and quantify traits that may serve as diagnostic predictors of strain performance in manufacturing and under field conditions. Analyze assay outputs to define biologically meaningful trait signatures associated with robustness, manufacturability, and efficacy. Use assay-derived data to address fundamental questions about which microbial traits best predict success across laboratory, fermentor, and field contexts to help develop predictive models for translation from in vitro to real-life environment. Work closely with colleagues in microbiology, fermentation, formulation, automation, and data science to integrate assays into the broader biosolutions development pipeline. Document methods, validation criteria, and workflows to ensure reproducibility and long-term platform utility. Contribute to the department’s teaching via e.g. lectures in courses, supervision of project groups and BSc and MSc thesis work. Your profile: PhD in experimental microbiology focused on bacteria and fungi. Experience with high-throughput screening (HTS) platforms and assay miniaturization Track record of designing, optimizing and troubleshooting automated workflow using liquid handling systems (Tecan, Hamilton, Opentron). Solid experience with translating manual protocols to robotics-assisted workflow. based on your understanding of experimental design, and the importance of reproducibility, and quality control when working with biological systems. Proficient in Python for instrument control, workflow scripting, and data processing. Strong problem-solving mindset with focus on scalability, robustness, and efficiency. Furthermore, you have effective communication, collaboration, and people skills, enabling effective interaction across diverse scientific teams and disciplines. As a formal qualification, you must hold a PhD degree (or equivalent). We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3½ years. Start date is 1 June 2026, or soonest thereafter. The position is a full-time position. You can read more about career paths at DTU here. Further information  For further information, please contact ibis@dtu.dk; Attn: Rasmus Frandsen (Director of IBIS). You can read more about DTU Bioengineering at www.bioengineering.dtu.dk. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure  Your complete online application must be submitted no later than 19 April 2026

PhD scholarship in Engineering Stem Cell-Derived T Cells for Tissue-Centric Cancer Targeting

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If you are passionate about new technologies for T cell therapies, this PhD position offers an extraordinary opportunity to pioneer groundbreaking immunotherapy solutions. You will join an innovative project at DTU Health Tech focused on improving the differentiation of T cells from inducible pluripotent stem cells (iPSCs), with the long-term ambition of developing off-the-shelf T cell therapies. This is your chance to collaborate within a dynamic, interdisciplinary environment, substantially advancing your scientific career while addressing one of healthcare’s most urgent challenges. Responsibilities Your primary role will be to develop and validate nanoparticle-based biomaterials for interaction with T cells during the process of differentiation and design these to best mimic the ligand interactions that T cells meet during thymic development. You will collaborate closely within an interdisciplinary team at DTU Healthtech and engage actively with academic and clinical partners. Your primary tasks will be to: Select ligand for T cell interactions Construct and optimise nanoparticle for correct ligand presentation Test novel solutions in comparison to existing T cell differentiation protocols for generation of T cells from iPSCs. Genetic engineering of iPCS line to express CARs or TCRs or other targeting receptors Perform in vitro functional validation of iPCS-derived T cell product Evaluate therapeutic efficacy using cancer cell line models Execute and analyse pre-clinical in vivo experiments. Document and communicate results through scientific publications and presentations. Required qualifications: MSc in biotechnology, immunology, Pharmaceutical design and Engineering, or a related field. Experience in molecular biology techniques and cell culture systems. Strong background in T cell immunology Experience with Flow Cytometry Experience with Stem cell culturing and iPCS maintenance. Preferable experience with iPCS to T cell differentiation protocols Demonstrated ability in scientific communication and collaboration. You must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree. Approval and Enrolment The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education. Assessment The assessment of the applicants will be made by Professor Sine Reker Hadrup. We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and appointment terms  The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. Starting date: after mutual agreement, Full-time employee as PhD student.  You can read more about career paths at DTU here. Further information Further information may be obtained from Professor Sine Reker Hadrup (SIRHA@DTU.DK). You can read more about DTU Health Tech at www.healthtech.dtu.dk/english. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. Application procedure  Your complete online application must be submitted no later than 15 April 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: A letter motivating the application (cover letter) Curriculum vitae Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale You may apply prior to ob­tai­ning your master’s degree but cannot begin before having received it. Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now

Understanding the details of virus replication cycles

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About this position: Do you have a passion for understanding the details of virus replication cycles? Join our team! Our research projects focus on determining particle structures and infection mechanisms of human picornaviruses and flaviviruses, as well as bacteriophages infecting pathogenic bacteria. The Plevka Lab has access to cutting-edge cryo-EM equipment at our in-house core facility. Our work is supported by significant third-party funding, including an ERC Consolidator grant, ensuring freedom in pursuing our research endeavors. We are seeking creative, independent, and motivated colleagues with proven research experience relevant to this position. Candidates with expertise in virology or structural biology are particularly encouraged to apply. The ideal candidate profile: Must-have: A PhD degree or equivalent in virology, structural biology, biochemistry, molecular biology or related field Expertise in cryo-EM, cryo-ET, or X-ray crystallography is an advantage but not a requirement Experience with tissue culture work or genetic modification of bacteria and phages is a strong plus, as well as programming skills A publication record in peer-reviewed journals Fluency in English (spoken and written) Nice-to-have: Good communication and interpersonal skills Motivation and a collaborative mindset What we provide to you: Open access to CEITEC MU core facilities with state-of-the-art equipment and experienced staff Full-time contract An attractive salary (ERC-funded position) Flexible working hours Support for further education and professional development Benefits package: 6 weeks of paid vacation, medical insurance, financial contribution to meal and kindergarten/pension scheme, Multisport card, mental health care, sports lessons directly at the campus Daycare for children on Campus Support from: Welcome Office service before and after arrival Grant Office support Postdoc Peer Committee CEITEC events – workshops, conferences, lectures, training, family gatherings, etc. How to apply? Application deadline: 17.05.2026 Start date: flexible Applications, including a CV, motivation letter, list of publications, and contacts for at least two references, should be sent via e-application bellow. In case of any troubles with the e-application, please contact Darja Horáková (darja.horakova@ceitec.muni.cz).

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