Fixed-term

We are seeking an ambitious and dedicated researcher for a 2-year postdoctoral position in the field of microbial metabolism and experimental animal models for cardiometabolic diseases (CMD). The Postdoc will be part of the Research group for Gut, Microbes and Health at DTU National Food Institute. We investigate how diet and environmental factors in the gut affect the composition and activities of the gut microbiome, and how this, in turn, affects health. The research is furthermore part of the virtual research center Microbiome Health Initiative (MHI), funded by the Novo Nordisk Foundation, aiming to establish a potential causal link between the gut microbiome and cardiometabolic diseases (CMD). The research project will focus on identifying and characterizing novel biosynthetic pathways for microbially-derived molecules and understanding how microbial molecule production can be modulated for disease prevention and therapeutic benefit. Using a combination of computational approaches and experimental models, the work will investigate how targeted regulation, through diet, of gut microbial functions and microbial metabolites can influence host metabolism. These concepts will be explored and validated across a range of established animal models relevant to metabolic and cardiometabolic diseases. Responsibilities and qualifications As part of the Research Group for Gut, Microbes and Health and the Microbiome Health Initiative, you will collaborate with a diverse group of researchers with expertise across multiple aspects of microbiome research, both within DTU National Food Institute, in Denmark, and with international partners. Thus, we expect you to have a solid background in microbiology and experimental animal models, together with a broad and in-depth understanding of microbial metabolism and the enzymes involved in the biosynthesis of microbially derived molecules. Hands-on experience within vitro testing, microbiological assays, and gut microbiome and metabolome analyses is essential. The ideal candidate is ambitious, highly motivated, and able to work independently, with excellent written and spoken English skills. Experience with animal experimentation for cardiometabolic disease and dietary interventions is required, while experience with sequence-based analysis of bacterial communities and chemical characterization of microbial metabolites (e.g. LC-MS/MS) is considered a strong advantage Required skills and additional responsibilities include: Strong expertise in microbial metabolism and cardiometabolic disease, with experience in computational and in vitro methods for studying host-microbe interactions. Extensive experience in designing, conducting, and analyzing animal experiments using both small and large animal models of cardiometabolic disease. Conduct independent research projects, from initial conception and design through to completion. Communicate research results: presenting data at national and international conferences and meetings, writing reports and manuscripts for publication. Supervise BSc and/or MSc students and potentially PhD projects. Contribute with teaching in educational course(s). Having prior experience with some, or all, of the listed responsibilities will be reviewed favorable. As a formal qualification, you must hold a PhD degree (or equivalent). We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and terms of employment  The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The starting date is 1 June 2026 (or according to mutual agreement). The position is a full-time position. The period of employment is 2 years. You can read more about career paths at DTU here. Further information  Further information may be obtained from Senior Researcher and Head of Research Group, Martin Steen Mortensen on  masmo@food.dtu.dk. You can read more about DTU National Food Institute at DTU National Food Institute. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure  Your complete online application must be submitted no later than 6 March 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) CV Academic Diplomas (MSc/PhD – in English) List of publications Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now

Are you passionate about sustainability and reducing environmental impact in biomanufacturing? Global biomanufacturing is expanding rapidly, but current processes rely heavily on sugar-based feedstocks, which require farmland and contribute to greenhouse gas emissions. Additionally, yeast-based protein production generates heat, demanding significant cooling to maintain productivity. Do you want to contribute to cutting-edge research that enables greener production of proteins and peptides by developing tomorrow’s super producers? Two post doc position are available, in the area of sustainable recombinant protein manufacturing using the yeasts Saccharomyces cerevisiae (Postdoc position 1) or Komagataella phaffii (Pichia pastoris) (Postdoc position 2) as host organisms.  You will be part of an exciting academic/industrial collaboration between Professor Uffe Hasbro Mortensen at DTU Bioengineering and the Microbial Expression Engineering Department at Novo Nordisk aiming at expanding the carbon source repertoire and stress tolerance of these the industrially important production yeasts. The candidates will perform their work at department of Biotechnology and Biomedicine, DTU, and at the Microbial Expression Engineering Department at Novo Nordisk, Måløv. Responsibilities and qualifications As a postdoc, your primary skills will be: Design and execute experiments to identify key genetic factors for thermotolerance and alternative carbon utilization, including literature analysis, genetic crosses, and mutant library screening. Apply findings to engineer yeast strains with improved traits. Collaborate with interdisciplinary teams across academia and industry. Publish results in high-impact journals and present at international conferences. Prepare technical reports and project deliverables with high standards of accuracy and clarity. Teach and supervise BSc and MSc student projects, and be co-supervisor for PhD students We are looking for candidates with: Skills in molecular biology, synthetic biology, yeast genetics, or related fields. Strong knowledge of heterologous protein expression and optimization. Experience with high-throughput screening and genetic-engineering technology is preferred. Excellent communication skills and a collaborative mindset. Proficiency in English for documentation and communication in a multinational environment In addition we expect the candidates to have hands-on experience with microbial cultivation and strain engineering of Saccharomyces cerevisiae (Postdoc position 1) or of non-conventional yeasts, preferentially Komagataella phaffii (Postdoc position 2). The positions offer a chance to make a tangible impact on sustainable biomanufacturing while working at the intersection of fundamental research and industrial application working alongside world-class experts in molecular biology, synthetic biology, and industrial biotechnology.  It is an opportunity to acquire genetic engineering and strains developing skills from using the unique technologies and high throughput platforms available at the host laboratories. We expect the candidates to produce insights, which we will be able to publish in the high impact journals in the field as they will enable future construction of new more environmental friendly yeast based cell factories. Hence, the candidates will be in a superior position to further pursue a career in academic- or industrial biotechnology after completion of the project. As a formal qualification, you must hold a PhD degree (or equivalent). We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 2 years with 1 May 2026 , or as soon as possible, as starting date. You can read more about career paths at DTU here. Further information  Further information may be obtained from: Professor Uffe Mortensen, E-Mail: um@bio.dtu.dk You can read more about Department of Biotechnology and Biomedicine at https://www.bioengineering.dtu.dk Sr. Principal Scientist Inga Sig Nielsen Nørby, E-Mail: isnn@novonordisk.com – Novo Nordisk Center for Expression Engineering, R&D, Måløv. You can learn more about Novo Nordisk at www.novonordisk.com If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure  Your complete online application must be submitted no later than 13 March 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) CV Academic Diplomas (MSc/PhD – in English) List of publications List of references in your CV – or One or more letters of recommendation Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. Apply Now

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