Fixed-term

Do you want to contribute to improving human health? Join a leading research team dedicated to understanding how mitochondrial DNA (mtDNA) gene expression affect mitochondrial function in disease and ageing. At the Division of Molecular Metabolism, we combine fundamental basic scientific research with clinical perspectives in a collaborative and well-equipped environment. We are currently looking for 1–2 highly motivated postdoctoral researchers to join the research group of Nils-Göran Larsson. Our group values scientific curiosity and careful experimentation. We welcome motivated researchers eager to explore mitochondrial biology in depth and contribute to advancing the field. Division The Division of Molecular Metabolism, Department of Medical Biochemistry and Biophysics, is located at the modern Biomedicum laboratory building at Solna campus of Karolinska Institutet. Our research encompasses basic scientific approaches to understand the regulation of mitochondrial function and its control of metabolism as well as biochemical and genetic studies of patients with inherited mitochondrial diseases. We use biochemistry, molecular biology and a set of elaborate genetic mouse (Mus musculus) models to study molecular regulation of mitochondrial function. We also have access to cell lines and tissues from patients with mitochondrial disease for human validation of results. Modern -omics techniques, including single cell proteomics, play an important role in our analyses. We offer an outstanding research environment and a close interaction between basic science and clinical science and diagnostics at the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital, Stockholm, Sweden. Excellent access to the most advanced resources in molecular and cell biology is available at the department and at the national core facilities at the Science for Life Laboratory. https://ki.se/en/mbb/research-division-of-molecular-metabolism https://ki.se/en/mbb/nils-goran-larsson-group Duties Mitochondria are central to cellular metabolism, and mitochondrial dysfunction is implicated in a wide range of human diseases and in the ageing process. The postdoctoral researcher will independently pursue a main project and will be involved in collaborative efforts on other research projects within the group. The ongoing projects in the group include the organization and regulation of the mitochondrial genome, mechanisms controlling mitochondrial gene expression and maintenance, the role of mitochondria in ageing, and how mitochondrial dysfunction cause mitochondrial disease phenotypes and contributes to metabolic disorders, immune responses and cancer. The work will employ biochemical, molecular and cell biological approaches, various omics technologies, and advanced genetic models. Entry requirements Applications are invited from enthusiastic and motivated individuals with a PhD in molecular biology or genetics. We are interested in individuals with experience in biochemistry, molecular biology, mouse genetics and different -omics methods. Good documentation skills as well as proficiency in both spoken and written English are required. The successful candidates should be able and willing to pursue his/her own research project and to contribute to ongoing collaborative projects. Personal suitability is of great importance when evaluating the applicants. Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site. Location: Biomedicum, Solna Type of scholarship The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable. Application process An application must contain the following documents in English or Swedish: A complete resumé (max 2 pages) A complete list of publications A personal motivation letter, explaining your research interest (max 1 page) Contact information of at least two references The application is to be submitted on the Varbi recruitment system. Want to make a difference? Join us and contribute to better health for all Apply Now

Do you want to contribute to top quality medical research? The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. Our key words are multidisciplinary, bridging, national and international collaborations. The Research Group Marie Arsenian’s Research Group conducts research on the MYC family of oncoproteins and network, to uncover their contribution to tumorigenesis, differentiation, metabolism, and apoptosis in different types of cancer. We are a multicultural and dynamic group with many national and international collaborators. Your mission A highly motivated, skilled, and creative research assistant is needed to join our team. The successful candidate will work on a project aimed at understanding how targeting a part of the MYC oncoprotein influences tumor cell biology, particularly in the context of neuroblastoma. Key duties will include maintaining and culturing various cell lines, performing fluorescence microscopy to analyze cellular processes, and conducting experiments to assess the effects of different small molecule treatment on cell differentiation, proliferation, metabolism and apoptosis. The applicant will be expected to design and execute experiments, collect and analyze data, and contribute to the interpretation of results. Experience in cell culture and fluorescence microscopy techniques is required, as these are integral to the project. The research assistant will work closely with the research team, contributing to a collaborative and dynamic research environment. Additionally, they will have opportunities to learn advanced laboratory techniques and gain hands-on experience in cancer biology research. This position offers an exciting opportunity to contribute to a cutting-edge project with the potential to impact neuroblastoma treatment strategies. Your profile We are looking for an enthusiastic and driven person interested in our area of research and ready to explore new paths for cancer therapeutics. Requirements for the position:  The candidate should have a collaborative mindset, work productively in a team, and contribute to a good social and work environment in the laboratory. The applicant should hold a B.S or M.S in Biomedical Science and have a background in cancer biology. Fluency in English is a requirement. The candidate must be well familiar with standard molecular and cell biology techniques including: Cell culture and drug testing Lentivirus transduction Molecular biology techniques: qPCR and Western blot Immunofluorescence Imaging techniques and data analysis Basic knowledge on bioinformatics analysis Sample preparation and analysis of Proteomics and RNAseq Meritorious for the positions: Previous experience in research on tumor biology, neuroblastoma or metabolism is an advantage.   What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. Location: Solna https://ki.se/en/mtc/marie-arsenian-henriksson-group Choose to work at KI – Ten reasons why Application The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. Want to make a difference? Join us and contribute to better health for all Apply Now

Do you want to contribute to top quality medical research? Join the Ziegenhain lab, part of the Division of Medical systems bioengineering (https://ki.se/en/mbb/research-division-of-medical-systems-bioengineering) at the department of Medical Biochemistry and Biophysics. In our group we are interested in shedding light on central molecular processes in human cells, in particular with regards to the control of transcription and alternative splicing. For this, we develop and employ cutting edge single-cell sequencing and computational approaches. Your mission The successful candidate will be working as a research assistant in the group. The main project aims to decode alternative splicing programs in schizophrenia using modern single-cell sequencing approaches. The successful candidate will be an active member of the research group and collaboratively support other ongoing projects in the laboratory. Your profile We are recruiting an enthusiastic research assistant to work on exciting challenges in single cell genomics. The ideal candidate should have obtained a MSc degree in biotechnology, molecular biology or a related field. We are looking for candidates with solid experience in wet lab work.Candidates should be familiar with common molecular biology techniques and be comfortable with independent lab work. Experience with liquid handlers or in NGS/genomics work is meriting.Previous experience in analysis of single cell sequencing data are further meriting.All candidates must be able to fluently communicate in written and spoken English as well as demonstrate good team work skills. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site. This position is a collaborative project between the groups of Christoph Ziegenhain and Jens Hjerling-Leffler and will be co-supervised by both PIs. You will work in: A dynamic and supportive research environment with access to state-of-the-art single-cell genomics technology Two groups with expertise in psychiatric disorders, genomics, and bioinformatics Groups with unique access to patient cohorts Location:Solna Application Welcome to apply at the latest 25th March 2026. The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. Permanent position is initiated by a six months trial period. Want to make a difference? Join us and contribute to better health for all Apply Now

Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required. The research group Applications are invited for a PhD studentship in the laboratory of Joanna Rorbach. The laboratory offers a stimulating, international research environment as part of the Department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet, one of the world’s leading medical universities. The lab is located at Biomedicum, a state-of-the-art research facility at the Solna campus in Stockholm, Sweden. The doctoral student project and the duties of the doctoral student Mitochondria are essential organelles in all eukaryotes, providing the host cell with energy as well as diverse metabolic capacities. In humans, encodes thirteen polypeptides of the OXPHOS complexes, all of which are synthesised in the mitochondrial matrix by a process that requires the collaboration of more than one hundred nuclear-encoded proteins imported into the mitochondrion from the cytosol. Defects in mitochondrial DNA, or the apparatus required for its expression, cause OXPHOS deficiencies – a group of debilitating conditions that are amongst the most common inherited human diseases. As we lack basic information on the mechanisms mitochondria use to generate polypeptides, how defects in these processes contribute to human pathologies is still poorly understood. The objective of our research is to better understand how mitochondrial translation machinery is assembled and how it functions in response to different environmental signals. The successful candidate will employ cutting-edge technologies, including genetic modification, proteomics and cryo-EM to study these processes. Highly motivated, creative and curious students with an interest in molecular and structural biology are encouraged to apply. The candidate should be interested in understanding fundamental cellular mechanisms and show willingness to develop their own research questions. The ability to work well in the team environment is a prerequisite. Applicants should hold a masters’ degree (or equivalent) in biology, biochemistry, chemistry or another relevant life science. Excellent laboratory skills in molecular biology are required, with experience in at least one of the areas of mammalian tissue culture, advanced light microscopy and structural proteomics, being advantageous. What do we offer? A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care. Eligibility requirements for doctoral education In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline. It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education. A) General eligibility requirement You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you: have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or have acquired substantially equivalent knowledge in some other way in Sweden or abroad.* Follow the instructions on the web page Entry requirements (eligibility) for doctoral education. *If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education. B) Specific eligibility requirement You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you: – Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school. Follow the instructions on the web page English language requirements for doctoral education. Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action. (A) and (B) can only be certified by the documentation requirement for doctoral education. Skills and personal qualities We are seeking a highly motivated and independent PhD student with a strong interest in molecular biology and biochemistry. The doctoral student will plan and perform experimental studies, analyze and interpret data, present results, and contribute to manuscript preparation in an interactive and collaborative research environment. Qualifications We are looking for ambitious and driven candidates with a solid background in biochemistry, biology, medicine or a related field. Applicants must have demonstrated the ability to conduct independent experimental work or smaller research projects, and must be fluent in spoken and written English. Terms and conditions The doctoral student will be employed on a doctoral studentship maximum 4 years full-time. Application process Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish. Your application must contain the following documents: – A personal letter and a curriculum vitae – Degree projects and previous publications, if any – Any other documentation showing the desirable skills and personal qualities described above – Documents certifying your general eligibility (see A above) – Documents certifying your specific eligibility (see B above) Selection A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants

Do you want to contribute to improving human health? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required. The research group Chronic liver disease is a rapidly growing global health problem and an increasingly important cause of morbidity and mortality. A central challenge in hepatology is identifying individuals at risk of developing advanced liver disease before irreversible damage occurs. The Hagström research group at the Department of Medicine, Huddinge, conducts internationally recognized research in clinical and population-based epidemiology of liver disease, with a particular focus on steatotic liver disease and its metabolic risk factors. Our work combines clinical cohorts, large-scale epidemiological data, and advanced statistical modeling to improve prediction of disease progression and long-term outcomes. As a doctoral student in our group, you will work in an interdisciplinary environment that includes clinicians, epidemiologists, biostatisticians and data scientists. You will be offered an individual research project within a highly productive research group with supervision by experienced researchers in clinical epidemiology and hepatology. The research uses unique data sources, including detailed clinical cohorts, nationwide Swedish health registers and large population-based studies. These data enable innovative research aimed at understanding the drivers of liver disease and improving early detection of individuals at risk. You will also be offered a wide range of doctoral courses and training opportunities as well as opportunities for international collaborations and exchanges. The doctoral student project and the duties of the doctoral student The aim of this PhD project is to improve prediction of future liver disease and its complications using large-scale clinical and population data. The project will focus on identifying clinical and metabolic markers that can predict progression from early metabolic dysfunction to advanced liver disease, including cirrhosis and liver failure. Key research areas include: Investigating whether routine clinical biomarkers can predict long-term risk of advanced liver disease in individuals with metabolic risk factors such as obesity and type 2 diabetes. Studying the interaction between metabolic dysfunction and alcohol consumption in determining the risk of severe liver disease. Developing and evaluating risk prediction models for future liver-related outcomes using data from primary care cohorts, diabetes cohorts and national health registers. Through these projects, the doctoral student will contribute to improving our understanding of who develops advanced liver disease and why, with the long-term goal of informing screening strategies and preventive interventions. The doctoral student will primarily work with epidemiological study design, statistical modeling, and analysis of large-scale health data, and will also participate in scientific writing and presentation of research findings. What do we offer? A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care. Eligibility requirements for doctoral education In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline. It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education. A) General eligibility requirement You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you: have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level,or have acquired substantially equivalent knowledge in some other way in Sweden or abroad.* Follow the instructions on the web page Entry requirements (eligibility) for doctoral education. *If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education. B) Specific eligibility requirement You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you: – Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school. Follow the instructions on the web page English language requirements for doctoral education. Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action. (A) and (B) can only be certified by the documentation requirement for doctoral education. Skills and personal qualities Requirements The applicant must: Hold a relevant degree in medicine, epidemiology, biostatistics, public health, or a related field Demonstrate a strong interest in metabolic disease and clinical epidemiology Have experience or training in epidemiology or quantitative research methods Be comfortable working with large-scale datasets Be fluent in English, both written and spoken Be able to work both independently and collaboratively in an international research environment Meritorious qualifications The following qualifications are considered advantageous: Programming skills in R, SAS, Stata or similar statistical software Experience with register-based research, particularly using Nordic health registers Experience in statistical modeling or risk prediction Experience with scientific writing, literature review and publication of research findings Experience in liver disease epidemiology A strong interest in data-driven research and interdisciplinary collaboration We place great emphasis on personal suitability. Terms and conditions The doctoral student will be employed on a doctoral studentship maximum 4 years full-time. Application process Submit your application and supporting documents through