Fixed-term

Creating knowledge. Doing meaningful work. Shaping the future. This is what the University of Münster stands for – one of Germany’s leading research universities and one of the region’s largest employers. Over 7,000 employees are committed every day to cutting-edge international research and excellent teaching. What unites us is more than just a workplace: it’s the ambition to make a difference together – regionally and internationally. Diversity, openness, and freedom for individual ideas characterize our daily work. Become part of our team in academia, technology, skilled trades, or administration. The Institute of Pharmaceutical and Medicinal Chemistry (Prof. Dr. Björn Burckhardt’s research group) in Department 12 at the University of Münster is seeking to fill the following position starting August 1, 2026: Research Associate (E 13 TV-L)   The position is to be filled. A part-time position (50%) is offered, limited to a term of 3 years. The Burckhardt research group focuses on the mass spectrometric investigation of key, pathophysiologically relevant peptide cascades in humans. A particular focus is the kallikrein-kinin system, which is closely linked to the renin-angiotensin-aldosterone system, the complement system, and neurokinins, but whose complex interplay remains insufficiently described. The kallikrein-kinin system plays a significant role in widespread diseases such as hypertension, diabetes mellitus, and cancer, as well as in rare diseases like hereditary angioedema and inflammatory conditions such as sepsis and malaria. A better understanding of these cascades and their interactions is expected to lead to new therapeutic approaches. Furthermore, (pre)clinical studies of new drugs are being conducted to optimize existing treatment concepts for these diseases. Your tasks: Using state-of-the-art (imaging) mass spectrometry, research is conducted on peptide/protein cascades in the body’s own regulatory circuits in healthy and diseased individuals. Development, validation and application of mass spectrometric methods to biological samples (plasma, urine, tissue, etc.) for (pre-)clinical research questions The position involves carrying out a doctoral research project. Supportive collaboration in multicenter clinical trials Writing scientific texts regarding the results obtained during research activities and publishing them Imparting specialist knowledge to students and instruction in the application of scientific methods Our expectations: A university degree in a natural science field, such as pharmacy, chemistry, biochemistry, biomedicine, bio/pharmaceutical technology and related disciplines, completed with above-average grades is required. Proven experience in applying basic and advanced scientific technologies to transfer research into industrial practice Relevant internships in academia or the pharmaceutical industry are welcome. Experience with mass spectrometry and HPLC is advantageous. Great interest in questions in the field of pharmacokinetics/pharmacodynamics Willingness and ability to work in interdisciplinary and international teams Excellent German and English skills, both spoken and written. Furthermore, an independent work style, teamwork skills, good communication and organizational skills are expected. Your benefit: Scientific work with the aim of obtaining a doctorate in a very active and very well-connected research team Appreciation, commitment, openness and respect – these are values ​​that are important to us. Whether it’s caregiving or childcare – our Family Service Office offers you concrete support services to help you balance your private and professional life. Your individual, tailor-made training and further education is not only important to us as an educational institution, but a matter close to our hearts. From Aikido to Zumba – our sports and health offerings from A to Z ensure your work-life balance. They benefit from numerous public service perks such as an attractive company pension scheme ( VBL ), an annual bonus payment and a workplace that is hardly affected by economic fluctuations. The University of Münster is committed to equal opportunities and diversity . We welcome all applications regardless of gender, nationality, ethnic or social origin, religion or belief, disability, age, or sexual orientation or identity. Providing family-friendly working conditions is a matter of course for us. Applications from women are expressly encouraged. In cases of equal suitability, qualifications, and professional performance, women will be given preferential consideration unless there are overriding reasons related to a male applicant. If you have any questions beforehand, please feel free to contact Prof. Dr. Björn Burckhardt ( burckhardt@uni-muenster.de ). Have we sparked your interest? Then we look forward to receiving your application by May 31, 2026 , exclusively as a single PDF file to burckhardt@uni-muenster.de . Please note that we cannot accept other file formats.

The Medical Imaging Center Light Microscopy (MIC-LM) employs a wide range of technologies for imaging and image analysis and is equipped with state-of-the-art microscopes, for example to perform Structured Illumination Microscopy (SIM), Photoactivated Localization Microscopy (PALM), and Fluorescence Lifetime Imaging Microscopy (FLIM). The MIC-LM is integrated in interdisciplinary projects focusing on cell biology, biomedical molecular biology, immunology, host-pathogen interactions, microbiology, and neurobiology. MIC-LM is embedded within the Medical Research Services Core Facilities and actively contributes to various national and international research consortia, fostering an interactive scientific environment. The MIC-LM is seeking to recruit a highly motivated scientist to join its team and work in a highly stimulating academic research environment. The successful candidate should have a strong background in advanced light microscopy, ideally including super-resolution microscopy, and an interest in the establishment and development of imaging technologies. Remuneration will be based on qualifications and the salary structure of the TV-L (public service tariff scale). The initial contract is limited to three years. Your tasks: Establish, apply and support advanced light microscopy techniques including confocal laser scanning microscopy, fluorescence lifetime and super-resolution microscopy, as well as automated microscopy. Generate workflows for automated image acquisition and quantitative analysis, including segmentation and machine learning-assisted image processing and data analysis. Manage and organize data acquisition and facilitate access to computing resources for image analysis. Advise and assist users with experimental planning, execution, and analysis. Train staff and users in image acquisition and analysis techniques through workshops and practical courses. Maintain microscopes and computer work stations. Your profile: Ph.D. in physics, biology, biochemistry, chemistry or equivalent qualification, with strong expertise in light microscopy. Proven ability to design, implement, and optimize microscopy-based experiments using advanced light microscopy techniques. Experience in quantitative image analysis and data management, ideally including automated or machine learning-based segmentation approaches. Analytical and organizational skills, and the ability to work independently and to coordinate collaborative projects. Ability to work in an international team. Fluent in English; German knowledge is advantageous but not essential. We offer: Team-oriented collaboration in a committed, international and appreciative team A friendly and collegial environment Extensive training and development opportunities Challenging and versatile tasks Further information: The position is salaried and based on the collective agreement of the Länder (TV-L). If the personal and collective agreement requirements are met, the employee will receive pay grade E13 TV-L. Further information can be found at https://oeffentlicher-dienst.info/ (in German). The place of work is Ruhr University Bochum. If the position is funded by third-party funds the employee has no teaching obligation. RUB sees itself as a university with an international presence. The campus languages are German and English. Competence in at least one of the two languages and the willingness to learn the other are a prerequisite. RUB provides corresponding free courses for employees.  German language courses are offered by the University Language Center (ZFA) in the field of German as a Foreign Language (DaF). https://www.daf.ruhr-uni-bochum.de/sbgk/index.html.en The Staff Council has the right to participate in all selection interviews. At the request of a candidate (m/f/x), it will ensure its participation in the entire procedure. Please contact wpr@rub.de. Contact persons for further information: Dr. Konstanze Winklhofer +49 234 32 28428Dr. Verian Bader +49 234 32 17612 Travel costs, accommodation costs and loss of earnings or other application costs for job interviews can unfortunately not be reimbursed. We look forward to receiving your application via our online application portal by 2026-06-22. Please make sure to mention the reference number ANR 5580. Apply Now

Neutrophils and macrophages belong to the first line of defense in the innate immune response: highly specialized in phagocytosis, they engulf invading pathogens and kill them in the phagolysosome using a toxic cocktail of reactive oxygen species and lytic factors. During this so-called oxidative burst, hypochlorous acid, a very strong oxidizing agent is produced, capable of modifying a wide range of different functional groups in biomolecules. The candidate will particularly focus on the oxidation of thiol groups and N-chlorination of amines. The successful candidate will use specific chemical and genetically encoded probes, lipidomics, and other biochemical and molecular biological tools to investigate which modifications hypochlorous acid induces in the cell envelope of bacteria (and the host). Furthermore, the influence of these modifications on bacterial physiology and host-pathogen interactions, and how bacteria protect themselves against these modifications will be elucidated. This three-year doctoral project lies at the intersection of redox biology and host-pathogen interactions. Your responsibilities will include independent planning and carrying out of experiments and data analysis, as well as contributing to the project’s further development and publication. You can expect a welcoming and supportive team. Your tasks: Microbiological and molecular biological work: (Co-)cultivation of bacteria & human cells, cloning and deletion mutagenesis, lipid isolation & analysis, heterologous expression & purification of proteins, fluorescence microscopy Biochemical assays: Working with liposomes & introducing redox probes into model membranes, analyzing the influence of N-chlorination on membranes using specific probes Specific techniques: Use of chemical probes for the detection of modified lipids & membrane proteins in combination with lipidomics & proteomics, use of redox & metabolite probes for the analysis of cellular homeostasis, transcriptome analysis for the identification of differentially regulated cellular pathways Supervision of bachelor’s and master’s theses, as well as co-supervision of advanced and specialized modules Literature review and hypothesis development, independent evaluation of results, and further development of the research project Your profile: We are looking for a candidate with an excellent master’s degree in biochemistry or biology, specialized in micro-/molecular biology, or a comparable degree. We welcome applications from candidates who have not yet fully completed their master’s thesis. The position requires the ability to independently plan and conduct experiments in molecular biology, as well as at least a basic understanding of microbiological work. Experience in one of the following topics is beneficial: Microbiology Cell culture with human cell lines Working with biological membranes Redox biology We are looking for a reliable and scientifically enthusiastic individual who enjoys working in a team and is willing to establish novel methods and present their work in a scientific setting. Excellent English skills are required. Please provide your application as single PDF file in the online application system. We offer: Challenging and varied tasks with a high level of personal responsibility. Structured PhD by regular feedback & exchange and integration in the IGB (International Graduate School Biosciences) Formal integration into the RUB Research School and benefits from the offered mentoring programs and courses Employment at one of the largest universities in Germany within the University Alliance Ruhr A friendly and welcoming work environment Networking opportunities at international scientific conferences A family-friendly working environment supported by structures at the RUB Further information: The position is salaried and based on the collective agreement of the Länder (TV-L). If the personal and collective agreement requirements are met, the employee will receive pay grade TVL E13 TV-L. Further information can be found at https://oeffentlicher-dienst.info/ (in German). The place of work is Ruhr University Bochum. If the position is funded by third-party funds the employee has no teaching obligation. RUB sees itself as a university with an international presence. The campus languages are German and English. Competence in at least one of the two languages and the willingness to learn the other are a prerequisite. RUB provides corresponding free courses for employees.  German language courses are offered by the University Language Center (ZFA) in the field of German as a Foreign Language (DaF). https://www.daf.ruhr-uni-bochum.de/sbgk/index.html.en The Staff Council has the right to participate in all selection interviews. At the request of a candidate (m/f/x), it will ensure its participation in the entire procedure. Please contact wpr@rub.de. Contact persons for further information: Dr. Lisa Knoke Tel.: +49 234 32 24879 Travel costs, accommodation costs and loss of earnings or other application costs for job interviews can unfortunately not be reimbursed. We look forward to receiving your application via our online application portal by 2026-06-01. Please make sure to mention the reference number ANR 5676. Apply Now