Fixed-term

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Inflammation as a Treatment Target in Chronic Radiation-Induced Bowel Dysfunction The Department of Oncology is located at the Institute of Clinical Sciences at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral studies in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about doctoral studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Radiotherapy is one of our most powerful tools against cancer, but unfortunately it also affects healthy tissue. This is a significant problem when radiation is directed at a tumor in the pelvic region, such as in gynecological cancer, prostate cancer, rectal- or anal cancer, since the intestinal wall is highly sensitive to radiation. Impaired intestinal health affects the quality of life of a very large group of cancer survivors and is a limiting factor in radiotherapy. The long-lasting underlying changes in the irradiated intestinal wall have not been thoroughly characterized, and effective treatment for the symptoms is lacking. The overarching aim of our research is to prevent and combat the chronic intestinal dysfunctions that may arise after radiotherapy to the pelvic region. We are now advertising a PhD position that combines both basic research and patient-oriented research with clear clinical relevance. The PhD student will be tasked with mapping the chronic changes in the intestinal mucosa that occur following radiation exposure, with a particular focus on low-grade inflammation, and investigating how these changes contribute to intestinal symptoms. This includes laboratory work that combines advanced omics analyses with basic laboratory techniques and questionnaires on intestinal health. The PhD student will also be involved in the implementation of a clinical pilot study testing a pharmacological intervention for radiation-induced intestinal disorders. The work will include, among other things, the development of study protocols in collaboration with clinical staff and researchers, coordination of the study’s implementation, and the collection and analysis of biological samples. The PhD student is also expected to compile, present, and publish the results in scientific contexts. We are seeking a PhD candidate with a strong interest in translational research with a background in  relevant subject area. Clinical experience is considered a merit, as is prior experience with laboratory work. Good proficiency in Swedish, both spoken and written, is necessary as the research is closely linked to patient-oriented studies and the healthcare system. Personal suitability is important, including good collaboration skills, conscientiousness, and the ability to work independently. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Clinical Sciences, Department of Oncology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Clinical Sciences requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Clinical Sciences has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Cecilia Bull, Associate Professor, Institute of Clinical Sciences, e-mail: cecilia.bull@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per this notice, and that

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Patient-based model systems for studying the role of the tumor microenvironment in cancer development and progression The Department of Laboratory Medicine is located at the Institute of Biomedicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Alterations in both cancer cells and their surrounding microenvironment play a critical role in tumor initiation and malignant behavior. Within the research group, an advanced patient-based model system has been developed enabling systematic investigation of how distinct tumor microenvironments influence cancer-related properties. These human-based models allow studies of key events in cancer development and progression ex vivo in a clinically relevant context, while remaining outside the patient. The aim of this PhD project is to reconstruct and study different stages of cancer development ex vivo to identify biomarker combinations and behaviours associated with tumor initiation and progression. The project will characterize how the tumor microenvironment regulates cancer behavior, as well as how cellular and matrix associated communication changes across different stages of cancer development. A goal is to identify molecular signatures with potential to improve early diagnosis and personalized cancer management. A PhD position is now advertised in a research group at the Sahlgrenska Center for Cancer Research led by Göran Landberg in collaboration with Anders Ståhlberg and Elinor Bexe Lindskog. The project will be conducted in a strong and internationally competitive research environment with broad expertise in translational cancer research. Patient-derived scaffolds (PDSs) generated from human tumors and cancer precursor lesions, with a focus on colorectal cancer, will be utilized. Relevant stromal and cancer cells will be cultured within patient-specific microenvironments to study the development of invasive cancer in relation to microenvironmental activity. The project will analyze secreted signaling molecules and key markers in both early and advanced cancer niches processed with advanced bioinformatics and AI-based approaches, with the aim of identifying novel biomarker combinations relevant to cancer development. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Laboratory Medicine. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Biomedicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Biomedicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Göran Landberg, Professor, Institute of Biomedicine, e-mail: goran.landberg@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline. You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral positionin Food and Nutrition The Department of Food and Nutrition, and Sport Science develops knowledge for a healthy and thriving world through food and sport. Our mission is to conduct education and research of world-class quality in food and nutrition science and sport science. The research is characterized by a clear educational connection, multidisciplinary collaborations and close contact with the outside world. The main focus of the department’s research is to develop and disseminate scientific knowledge and professional competence that can contribute to effectively promoting sustainable habits regarding sports, physical activity and food. The Department of Food and Nutrition, and Sport Science has two doctoral subjects: Food and Nutrition and Sport Science. At the Department of Food and Nutrition, and Sport Science, Food and Nutrition is a third-cycle subject with focus at people’s intersection with food, which is studied in a multidisciplinary perspective. The importance of diet in health promotion and disease prevention is central but aspects such as environment and performance are also addressed. Food and Nutrition includes studies on the actions, choices and habits of individuals and those responsible for diet. It may apply to meals as well as diets as a whole. Learning, behavioral change and people’s thoughts, attitudes and perceptions about diet are important starting points in research. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages. Doctoral studies | University of Gothenburg Duties  A doctoral student shall devote their time to third-cycle studies in accordance with the General syllabus for the subject in which they are admitted. The final goal of the programme is the doctoral degree. The doctoral student conducts research and is expected to contribute to the development of knowledge within the field. This includes developing their own ideas and communicating scientific results both orally and in writing. The doctoral student must develop the knowledge and skills required to independently conduct research within the subject through the production of a doctoral thesis. The position also aims to ensure that the doctoral student develops the ability to apply the scientific skills and knowledge acquired in further research or other qualified professional work. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree. As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for education at third-cycle level are: having completed a degree at second-cycle level, or the fulfilment of course requirements totaling at least 240 credits, of which at least 60 credits must be at second-cycle level, or the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for doctoral studies in Food and Nutrition require that the applicant has fulfilled course requirements of at least 90 credits in the subject of Food and Nutrition or in another subject of relevance to Food and Nutrion activities, of which 15 credits must consist of an independent project/thesis. A person who has acquired equivalent knowledge in another way within or outside the country also has special qualifications. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. When appointing, consideration will primarily be given to the degree of ability to benefit from the doctoral education. An overall assessment will be made of the research proposal and research orientation, the degree project/thesis, and other merits. Interviews will be conducted. Admission and selection will take place with due consideration of the department’s supervisory capacity within the applicant’s area of doctoral research. Only applicants who can be offered supervision and acceptable study conditions will be admitted. The doctoral student position is filled on the condition that the necessary decisions are made. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Form of employment: Fixed-term employment, corresponding to four years of full-time studies Place of employment: at The Department of Food and Nutrition, and Sport Science Extent: 100% Start date: 1st of September 2026, or by agreement The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at The Department of Food and Nutrition, and Sport Science require physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the department has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies. Contact information If you have any questions about the project, you are welcome to contact: Deputy Head of Department for Doctoral Education Andreas Fröberg, tel. 073-7227026, email andreas.froberg@gu.se   Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande  

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Broadly Neutralizing Antibodies for Therapeutic Use Against Influenza A Virus The Department of Microbiology and Immunology is located at the Institute of Biomedicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Influenza A virus (IAV) remains a serious pandemic threat, driven by zoonotic spillover and rapid antigenic drift. Viral glycoproteins hemagglutinin (HA) and neuraminidase (NA) are crucial for viral entry and release. Antibodies have the potential to neutralize the virus by blocking viral entry. At mucosal surfaces, antibodies of the IgA isotype are enriched and are thought to be particularly important in controlling infection. Our laboratory (www.angelettilab.com) is actively investigating how B cell differentiate in the upper airways and how antibodies are able to block influenza infection in mucosal tissues. The group is a dynamic and collaborative environment. This PhD project will combine antibody engineering with mucosal immunology. The core goals of the project are (1) to understand how antibody target (HA vs NA) and isotype (IgG vs IgA) shape antiviral function in airway mucus models and in vivo and (2) dissect basic immunological mechanisms leading to IgA class switching in the upper airways. In practice, the PhD student will utilize many methods, including: molecular biology for antibody engineering, cell culturing, influenza virus assays including neutralization, multicolor flow cytometry and in vivo work. The ideal candidate should have a strong experimental drive and want to work at the intersection of antibody engineering and mucosal immunology. Documented experience in any of the following is an advantage: immunology work, multicolor flow cytometry, Molecular biology / cloning / protein expression and virology or infection models. As in vivo work is an integral part of the project, the candidate should be willing to work with laboratory animals. We value genuine, personal applications. Please include concrete examples that link your experience to this project. If you use AI tools for language polishing, please state this briefly and ensure the content reflects your own experience and motivation. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Microbiology and Immunology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Biomedicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Biomedicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Davide Angeletti, Professor, Institute of Biomedicine, e-mail: davide.angeletti@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline. You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral positionin Medical Science Project title: Role of NOX2-derived reactive oxygen species in pancreatic ductal adenocarcinoma The Department of Microbiology and Immunology is located at the Institute of Biomedicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with limited therapeutic options and poor prognosis. A defining feature of PDAC is its dense desmoplastic stroma, which fosters an immunosuppressive tumor microenvironment (TME). This TME is heavily infiltrated by myeloid cells, expressing the reactive oxygen species (ROS)-forming enzyme NOX2. This PhD project investigates the role of NOX2-derived ROS in PDAC progression, with focus on how ROS influence tumor cell behavior, immune surveillance and metastatic spread. A combination of in vivo and ex vivo models will be employed, including syngeneic and orthotopic PDAC mouse models, as well as a three-dimensional scaffold-based system that mimics the PDAC tumor architecture. To assess clinical relevance, tumor biopsies from PDAC patients receiving perioperative treatment with a NOX2-inhibitor in a phase II clinical trial (PANCEP-1) will be analyzed, with particular attention to markers of epithelial-to-mesenchymal transition and myeloid cell infiltration. Together, these studies aim to clarify the multifaceted role of NOX2-derived ROS in PDAC. The project will provide a broad research experience for the doctoral student across molecular and cellular biology, in vivo and ex vivo model systems, clinical sample analysis and bioinformatics. The applicant should have a background in relevant discipline. Experience in cell-immunological research and relevant methods, such as cell culture, flow cytometry and bioinformatic analyses, is considered an asset. We also place great emphasis on personal suitability and strong collaborative skills. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Microbiology and Immunology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Biomedicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Biomedicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Anna Martner, Professor, Institute of Biomedicine, e-mail: anna.martner@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline. You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier. If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Targeting Lung Cancer Metabolism through Precision Nutrition and Glutathione Depletion The Department of Medical Biochemistry and Cell biology is located at the Institute of Biomedicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Lung cancer is one of the most common cancers and is associated with a poor prognosis in patients with advanced disease. Evidence from multiple studies suggests that lung cancer cells are vulnerable to oxidative stress and that reactive oxygen species may be exploited therapeutically. The overall aim of this project is to develop new cancer therapies targeting endogenous antioxidant systems. While drugs targeting cancer metabolism often encounter resistance due to metabolic plasticity, combining such approaches with precision nutrition, defined as tailored dietary interventions that constrain cancer cells in metabolically vulnerable states, may help overcome this limitation. Mild amino acid deprivation has been shown to trap lung cancer cells in a state of glutathione dependency, rendering them highly reliant on this antioxidant to prevent ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation. This vulnerability is mediated by activation of the integrated stress response, an adaptive pathway that enables cells to cope with metabolic and oxidative stress. In this thesis project, the mechanisms by which the integrated stress response regulates ferroptosis will be defined, with the goal of identifying targetable vulnerabilities. Precision nutrition strategies will be tested, and pro-oxidant therapies will be validated in mouse models and patient-derived lung cancer models to establish novel treatments and clinically relevant biomarkers. The program will introduce the PhD student to the rapidly advancing field of cancer metabolism, which is now recognized as a hallmark of cancer. The project will employ cutting-edge methodologies, including mass spectrometry-based metabolomics and patient-derived lung cancer models. The research will be conducted within the Precision Medicine Group at the Sahlgrenska Center for Cancer Research. The applicant should have a background in relevant discipline. Previous experience with cell culture, advanced microscopy, metabolic analyses, and basic cell biological techniques is considered an advantage. As the studies will include the use of experimental animals, prior experience or training in this area is also considered an advantage. Strong emphasis will be placed on personal qualities such as commitment, initiative, and the ability to collaborate effectively. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Medical Biochemistry and Cell biology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Biomedicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Biomedicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Per Lindahl, Professor, Institute of Biomedicine, e-mail: per.lindahl@wlab.gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per this

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Structural and functional analyses of mitochondrial biogenesis by cryo-EM The Department of Medical Biochemistry and Cell biology is located at the Institute of Biomedicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: Mitochondria convert chemical energy into ATP by oxidative phosphorylation. The complexes driving oxidative phosphorylation are a mosaic of proteins encoded by the nuclear and the mitochondrial DNA. Therefore, assembly of the respiratory chain and the ATPase requires not only expression and import of many nuclear encoded proteins but also synthesis of mitochondrially encoded proteins. Surprisingly little is known about mitochondrial translation. The main goal of this project is to unravel structurally and functionally how translation by mitochondrial ribosomes is connected to protein biogenesis and complex assembly. Specifically, we aim to determine structures of mitochondrial ribosomes bound to biogenesis factors, using single particle cryo-EM as the main method (Nat. Struct. Mol. Biol. 2019, 2025). In recent years, we have identified interactors of the mitochondrial ribosomal tunnel exit and characterized their functions (JCB 2011; Mol. Cell. 2020, 2020, 2023; NAR 2025). By this, we revealed novel pathways for protein biogenesis, translational regulation and quality control, but many of the identified ribosome interactors are yet poorly understood but likely influence yet unknown aspects of mitochondrial biogenesis. Because oxidative phosphorylation is crucial for cellular energy metabolism, defects of mitochondrial gene expression result in severe human diseases. Hence, the information emerging from this study will be relevant for basic as well as for medical sciences. Our group employs a large variety of methods ranging from protein biochemistry and molecular biology, genetics in yeast and mammalian cells to high-resolution single particle cryo-EM. For more information, see our homepage: www.martinottlab.com We are looking for a PhD student who is genuinely interested in basic molecular mechanisms. You should have experience in molecular analyses and profound knowledge in molecular biology, biochemistry, or structural biology, or a related field. Previous experiences with protein purification or structural methods are a merit. We value personal integrity as well as an interest and commitment to personal development. You should have a good ability to express yourself in English. You should also be able to work both independently and in a group. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Medical Biochemistry and Cell biology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Biomedicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Biomedicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor, Martin Ott, Professor, Institute of Biomedicine, phone: +46 722-61 28 71, e-mail: martin.ott@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande     Application You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal. It is your responsibility to ensure that the application is complete as per

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science Project title: Heart-Lung crosstalk and applications for heart failure prevention and treatment The Department of Molecular and Clinical Medicine is located at the Institute of Medicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. Our primary research focus at the department is on metabolism, diabetes, obesity and cardiovascular disease. We support and promote research and teaching in translational medicine to improve health and to benefit society. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages https://www.gu.se/en/doctoral-studies Duties  Doctoral education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Project: The major heart (heart failure) and lung (asthma, chronic pulmonary obstructive disease [COPD]) diseases frequently co-exist, which confers worse outcomes. The current PhD project will seek to systematically assess the importance of heart-lung interorgan crosstalk in the context of heart failure, asthma and COPD, using a combination of experimental and clinical study designs. Human genetic studies from our group have pointed to shared molecular pathways for heart and lung disease which are increased in the airways of asthma/COPD patients and targeted by current treatments, pointing to a role for interorgan crosstalk. The doctoral student will work with state-of-the-art in vitro and in vivo models of heart and lung disease, clinical human samples, and a variety of molecular biology methods. The project will also include analysis of clinical/epidemiological data, and may be tailored to the profile and interests of the student. The student will thus obtain broad perspectives on molecular medicine methods and translational perspectives including drug development and repurposing. The project will be conducted within the translational research unit led by professor Gustav Smith at the Wallenberg Laboratory of Gothenburg University. Tuition will include weekly mentor and group meetings, journal clubs, and retreats. The group includes experimental, bioinformatic and clinical PhD students, bioinformaticians, research nurses, postdoctoral and senior researchers. The group is passionate about excellent research on the international level but also a good working environment characterized by respect and consideration where we strive for all members to feel involved, stimulated and well supported. In summary, this PhD project offers a unique opportunity to work at the interface of cardiovascular and pulmonary research in a highly collaborative translational setting. Our research group is looking for a highly motivated, curious, and talented candidate with a background in, for example, molecular medicine, biomedicine, biology, bioinformatics, biomedical engineering, or related disciplines. Documented experience with cell culture, animal handling, basic molecular techniques like PCR, blotting, ELISAs and histology, and data analysis are a merit. Experience with vitro and in vivo models of heart or lung disease is also a merit. Emphasis will be placed on personal characteristics including communicative and collaborative skills as well as scientific curiosity. Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.  As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration. Eligibility  Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject. The general eligibility requirements for doctoral studies are: 1. having completed a degree at second-cycle level, or 2. the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or 3. the acquisition of equivalent knowledge in some other way, either in Sweden or abroad. Specific entry requirements for this subject, according to the general syllabus, are: having successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies. Assessment criteria  The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through an academic paper, degree project, scientific journals or the like. Admission and employment  Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Medicine requires physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the Institute of Medicine has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies.  Contact information For more information about the project please contact principal supervisor,

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. The Institute of Clinical Sciences is one of six Institutes within Sahlgrenska Academy at the University of Gothenburg. We conduct research and education that puts people’s health and quality of life in focus. We represent 16 different research areas and are divided into four sections.  Through a fruitful collaboration with the healthcare and Sahlgrenska University Hospital, we have developed joint projects and meeting places that benefits both health care and research The Institute of Clinical Sciences, Department of Surgery at the Sahlgrenska Academy at the University of Gothenburg invites applications for a position as associate researcher in cancer research. The research group has a strong desire to translate basic research findings into new treatment principles for rectal cancer. Duties The position as associate researcher will be linked to a research project focusing on the development and assessment of new models and treatment options for rectal cancer. The collection of methods that will be used in the project includes immunohistochemistry, gene expression analysis, culture and stimulation of primary cells and cell lines, organoids and cellular assays. Bioinformatics will also be part of the project. Qualifications To qualify as an associate researcher the applicant should hold a Master degree in relevant subject such as immunology or molecular biology. The applicant should have knowledge or interest in the field of cancer research, extensive experience of practical laboratory experience within immunology and/or cancer research. Other important qualities include documented experience in molecular biology techniques most importantly gene expression analyses. Previous experience of cell culture, immunohistochemistry and bioinformatics, as well as a strong self-motivation, good interpersonal skills, and fluency in writing and speaking English are also desirable. Finally, the assessment will also pay particular importance to personal suitability. Employment The employment is limited (temporary) for 6 months, 100% of full-time and is placed at the Institute of Clinical Sciences, Department of Surgery. Starting date: as soon as possible Contact information for the post If you have any questions about the position, please contact Professor Eva Angenete; email eva.angenete@gu.se or phone +46 31-3438410/ +46 760-514441. Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande Application To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. Applications must be received by: 2026-02-27 The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations. Salaries are set individually at the University. Apply Now

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. The Department of Chemistry and Molecular Biology conducts high-quality research and education in chemical sciences and molecular life sciences. Our research and education focuses on a deep understanding of chemical and biological processes in cells and in the environment. We are responsible for postgraduate education in the subject area Natural Sciences with a focus on chemistry, biophysics, biology and educational science. In addition, the department hosts educational programmes in molecular biology, bioinformatics, chemistry, organic chemistry and medicinal chemistry, as well as Bachelor’s Programme in Pharmacy/Dispensing Pharmacists. The department is an international environment with interdisciplinary collaborations in both research and education and contributes strongly to the University of Gothenburg’s top ranking in life science. We are centrally located in Natrium, Medicinareberget, Gothenburg. Tietze lab is a part of the Wallenberg Centre for Molecular and Translational Medicine (https://www.gu.se/en/molecular-translational-medicine) which translational research in the fields of metabolism, neuroscience, cancer, inflammation, degenerative diseases, genomics and life science chemistry.Tietze lab (www.tietze-lab.com) is dedicated to advancing bioinspired chemical engineering for the development of peptide-based molecules and materials. Our team focuses on creating innovative solutions for diagnostics and targeted drug delivery. Duties Plan, design, and execute peptide synthesis workflows using SPPS (manual and automated), including route selection, resin/strategy choice, optimization of coupling/deprotection conditions, and scale-up considerations. Develop and optimize purification strategies using preparative HPLC, including method development, gradient scouting, fraction strategy, yield/purity targets, and recovery optimization. Conduct advanced analytical characterization and troubleshooting using analytical HPLC and LC-MS, including method development/validation concepts, and root-cause investigations of synthesis/purification issues. Evaluation of bioactivity and functional performance of samples in vitro, and interpretation of structure-activity relationships (SAR). Perform and coordinate cell-based experimental work with bacterial and eukaryotic systems Documentation of experimental workflows to ensure traceability and reproducibility Equipment troubleshooting, and continuous improvement of lab workflows. Introduction of new group members into lab routines Qualifications Requirements for the position: Master’s degree (MSc) in Biology, or equivalent. Documented hands-on experience with solid-phase peptide synthesis (SPPS) (manual and/or automated). Strong practical experience with analytical methods for peptides, in particular HPLC and LC-MS, including sample preparation, routine method execution, and basic instrument-level troubleshooting. Experience with preparative HPLC and purification strategies. Experience with method development/optimization (e.g., gradient optimization, purity/yield optimization) under supervision or within project work. Hands-on experience with cell culture (bacterial and/or eukaryotic cells) and related laboratory techniques. Good ability to document experiments and results in a structured manner to ensure traceability and reproducibility (e.g., in an ELN/lab notebook). Very strong laboratory skills, attention to detail, and a quality-minded approach to practical work. Good collaboration skills and ability to work effectively in a team, contributing to a positive and well-structured laboratory environment. Excellent command of English, both spoken and written. Merits for the position: Experience working in a team and/or onboarding new laboratory team members. Proficiency in Swedish (spoken and/or written). Employment The employment is a fixed term during 360 days, fulltime, 100% at the Department of Chemistry and Molecular Biology. Contact information for the post If you have any questions about the position, you are welcome to contact Alesia A. Tietze, Professor in Medicinal Chemistry e-mail: alesia.a.tietze@gu.se Unions Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande Application In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system, Reach mee,. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application. The application must include Résumé/CV Cover Letter Contact information of at least two references, Copy of degree certificate, and other certificates/grades that you wish to be considered. The qualifications claimed must be documented, certified and translated into English. All attachments must be labelled in a way that clearly shows their content. Applications must be received by: 2026-02-26 Apply Now