Fixed-term

Job Description The NIISQ PhD scholarship is a prestigious scholarship supported by the National Injury Insurance Scheme Queensland and is part of a large program of research to develop treatment options for treating traumatic brain injury (TBI). We are looking for a highly motivated PhD candidate to develop novel trans-nasal delivery methods such as peptides and micellar formulations, for targeted delivery of different therapeutic agents such as drugs, extracellular vesicles, growth factors and other such small bioactive molecules, for repairing traumatic brain injuries. The position is part of the Cure Traumatic Brain Injury project which focuses on identifying and testing therapeutic cellular and subcellular products suitable for translation to the clinic. The team has the ambitious aim of driving products into clinical trial within five years. The primary focus of this PhD position is to i) systematically explore the different carriers for trans-nasal delivery of different molecules and/or cell components ii) characterise and optimise these carriers/vehicles from an application viewpoint, and iii) test the efficiency of these approaches in rodent models of TBI. Success in this role requires i) an innovative, entrepreneurial attitude with a passion to deliver products to market, (ii) a focus on consumer involvement, (iii) ability to work with clinicians, (iv) aptitude to work both autonomously and co-operatively within a large team, (v) drive and imagination to contribute to science. Qualifications The selection of applicants for the award of higher degree research scholarships at Griffith University involves consideration of your academic merit and research background. To be successful within this role, a scientific background in neuroscience and cell biology is desirable. You will have evidence of a passion for conducting basic and translational research, with a strong desire to undertake research in neural repair. Expressions of interest are welcome from domestic applicants, and from international applicants who have a reasonable expectation of being able to obtain a student visa for study in Australia. Applicants must have completed, or expect to complete, a bachelors degree with honours equivalent to Second class (2A) honours or a Masters degree incorporating a significant research component of a standard comparable to a bachelor honours degree or be regarded by Griffith University as having an equivalent level of attainment. For further information on the eligibility requirements for the program refer here. Applicants are expected to commence in 2026. Additional Information About the scholarshipThe NIISQ scholarship has an annual stipend of $50,000 for a period of up to three years of full-time study. What Griffith offersAs a scholarship holder, you will study with a University that ranks among the top 2% worldwide and spans across campuses in South East Queensland. At Griffith University, we’ve worked hard to create a culture that will challenge you to be curious, creative and courageous. We also support the professional and personal development of all our HDR candidates and invest in the skills of our people. Griffith University values diversity, inclusion and flexibility and we encourage Aboriginal and Torres Strait Islander, and people of all backgrounds to apply. Griffith’s strategic goals are to also increase the proportion of women in senior academic and administrative roles and in Science, Technology, Engineering, Mathematics and Medicine (STEMM). EOI ProcessPlease do not select the “APPLY” button. All expressions of interest must be submitted to Dr Ronak Reshamwala, at r.reshamwala@griffith.edu.au containing: Statement addressing your suitability for the project/scholarship Evidence that you have completed a program with the required grades as detailed in the about you section A curriculum vitae (CV) Names of two referees Closing date for expressions of interest is: Friday 3 July 2026 5pm AEST The preferred applicant will then be invited to apply for the program and scholarship on-line For project related enquiries please contact:Dr Ronak ReshamwalaEmail: r.reshamwala@griffith.edu.au For administration enquiries please contact:Griffith Graduate Research SchoolEmail: hdr-scholarship@griffith.edu.au Apply Now

Job Description The NIISQ PhD scholarship is a prestigious scholarship supported by the National Injury Insurance Scheme Queensland and is part of a large program of research to develop treatment options for treating traumatic brain injury (TBI). We are looking for a highly motivated PhD candidate to pioneer the development of novel clinically relevant models of traumatic brain injury. The position is part of the Cure Traumatic Brain Injury project which focuses on identifying and testing therapeutic cellular and subcellular products suitable for translation to the clinic. The team has the ambitious aim of driving products into clinical trial within five years. The primary focus of this PhD position is to i) systematically develop three-dimensional cellular models to recapitulate the complexity of the brain ii) subject cell models to controlled TBI in vitro iii) characterise the response to injury and benchmark data from the model against existing human clinical data. Success in this role requires i) an innovative, entrepreneurial attitude with a passion to deliver products to market, (ii) a focus on consumer involvement, (iii) ability to work with clinicians, (iv) aptitude to work both autonomously and co-operatively within a large team, (v) drive and imagination to contribute to science. Qualifications The selection of applicants for the award of higher degree research scholarships at Griffith University involves consideration of your academic merit and research background. To be successful within this role, a scientific background in neuroscience and cell biology is desirable. You will have evidence of a passion for conducting basic and translational research, with a strong desire to undertake research in neural repair. Expressions of interest are welcome from domestic applicants, and from international applicants who have a reasonable expectation of being able to obtain a student visa for study in Australia. Applicants must have completed, or expect to complete, a bachelors degree with honours equivalent to Second class (2A) honours or a Masters degree incorporating a significant research component of a standard comparable to a bachelor honours degree or be regarded by Griffith University as having an equivalent level of attainment. For further information on the eligibility requirements for the program refer here. Applicants are expected to commence in either 2026 or 2027. Additional Information About the scholarshipThe NIISQ scholarship has an annual stipend of $50,000 for a period of up to three years of full-time study. What Griffith offersAs a scholarship holder, you will study with a University that ranks among the top 2% worldwide and spans across campuses in South East Queensland. At Griffith University, we’ve worked hard to create a culture that will challenge you to be curious, creative and courageous. We also support the professional and personal development of all our HDR candidates and invest in the skills of our people. Griffith University values diversity, inclusion and flexibility and we encourage Aboriginal and Torres Strait Islander, and people of all backgrounds to apply. Griffith’s strategic goals are to also increase the proportion of women in senior academic and administrative roles and in Science, Technology, Engineering, Mathematics and Medicine (STEMM). EOI ProcessPlease do not select the “APPLY” button. All expressions of interest must be submitted to Dr Mariyam Murtaza at m.murtaza@griffith.edu.au, containing: Statement addressing your suitability for the project/scholarship Evidence that you have completed a program with the required grades as detailed in the about you section A curriculum vitae (CV) Names of two referees Closing date for expressions of interest is: Friday 3 July 2026 5pm AEST The preferred applicant will then be invited to apply for the program and scholarship on-line For project related enquiries please contact:Dr Mariyam MurtazaEmail: m.murtaza@griffith.edu.au For administration enquiries please contact:Griffith Graduate Research SchoolEmail: hdr-scholarship@griffith.edu.au Apply Now

The Position The position is in support of establishing a protein structure determination and engineering pipeline in the Zhang lab. The position will contribute to developing novel strategies to control devastating diseases in agriculture and Australian native plants. The position will Involve protein characterisation and structure determination using computational modelling and wet-lab techniques including X-ray crystallography. The Person The successful applicant will undertake independent research in the area of protein chemistry and structural biology with a view to publishing original and innovative results in refereed journals, present research at seminars and conferences, and collaborate with other researchers. The successful applicant will hold a relevant PhD, with experience in recombinant protein production, X-ray crystallography and protein structure modelling and analysis. Experience in protein evolution and high throughput library screening to detect protein-protein interaction In different cell systems will be regarded positively. The School/Department The Research School of Chemistry is a leading centre of chemistry research in Australia. Researchers have a tradition of excellence in addressing the world’s most pressing chemistry issues, including computational chemistry. The College/Division The ANU College of Science and Medicine (CoSM) encompasses the disciplines of: Astronomy and Astrophysics, Biology, Chemistry, Earth Sciences, Medical Research, Medicine and Psychology, and Physics. Staff and students within the ANU College of Science and Medicine conduct research and deliver a research-led education program that encompasses the entire breadth of the sciences, supported by extensive international networks and by world-class facilities. For further information please contact, Dr. Xiaoxiao Zhang, E: Xiaoxiao.zhang1@anu.edu.au.   The University actively encourages applications from Aboriginal and Torres Strait Islander people. For more information on employment opportunities, contact our Indigenous Employment Consultant on indigenous.employment@anu.edu.au  ANU values diversity and inclusion and is committed to providing equal employment opportunities to people of all backgrounds and identities.  For more information about staff equity at ANU, click here. For enquiries about the application process, or if you require reasonable adjustment to apply for this role, please contact the hiring manager on the above listed details. Application information In order to apply for this role please make sure that you upload the following documents: A statement addressing the selection criteria. A current curriculum vitae (CV) which includes the names and contact details of at least three referees (preferably including a current or previous supervisor). If your CV does not include referees you can complete these online when prompted in the application form. Other documents, if required. Applications which do not address the selection criteria may not be considered for the position. Please note: The successful candidate will be required to undergo a background check during the recruitment process. An offer of employment is conditional on satisfactory results. Apply Now

Position Summary  The Barua Lab is seeking up to 3 highly motivated Postdoctoral Research Fellows for full-time, two-year positions at the University Health Network (UHN). Applicants should be in the top 5% of candidates within their field, with multiple high-impact research outputs and high potential for broad impact. Those with research experience collaborating with industry partners and/or commercialization experience are preferred. Successful applicants will join the laboratory of Dr. Moumita Barua. The 2 major project subtypes include human omics research utilizing large cohorts like the UK Biobank and All of Us; or mechanistic projects exploring genetic kidney disorders including Alport syndrome, congenital anomalies of the kidney and urinary tract (CAKUT), and Joubert syndrome. The laboratory is located in the research tower attached to Toronto General Hospital and is supported by peer-reviewed funding (CIHR, Kidney Foundation of Canada) and philanthropic awards. Dr. Moumita Barua is a Clinician Scientist at the University Health Network (UHN), Senior Scientist at the Toronto General Hospital Research Institute, and Associate Professor of Medicine at the University of Toronto. Her research program aims to improve diagnostics and clinical outcomes for individuals living with kidney disease. The Barua Lab integrates human genetics, molecular biology, and preclinical modeling to elucidate disease mechanisms and identify therapeutic targets. Genetic discoveries from patient and population cohorts guide the development of clinically relevant models in the lab. Major ongoing projects include: Genome-wide and other omic association studies of kidney traits, Pax2 mediated kidney repair and regeneration, and Mechanistic studies in genetic kidney disease models including for Alport syndrome, CAKUT and Joubert syndrome. Duties Design and execute molecular biology experiments involving next-generation and single-cell sequencing workflows. Analyze and interpret large-scale multi-omics datasets (epigenomic, transcriptomic, and proteomic). Conduct preclinical studies using mouse models of kidney disease. Collaborate with laboratory scientists to validate and integrate findings. Prepare manuscripts, presentations, and scientific reports. Contribute to grant applications and progress reporting. Qualifications PhD obtained in the last 5 years, or MD or DDS in the last 10 years in molecular biology, bioinformatics, genomics, biomedical sciences, or a related field. Applicant cannot already be at UHN. Experience with genetically characterized cohorts is required Proven experience working with large datasets and performing statistical analyses. Proficiency in next-generation sequencing (WGS, WES, RNA-seq, single-cell sequencing). Hands-on experience with single-cell sequencing technologies and associated analysis tools. Experience generating or analyzing proteomics data (e.g., mass spectrometry). Strong understanding of kidney disease biology or demonstrated interest in renal pathophysiology. Familiarity with mouse models, including handling, genotyping, and phenotypic characterization. Experience in collaborative, interdisciplinary research environments. Background in systems biology or network-based modeling (asset). Prior experience with translational research or preclinical models of kidney disease (asset). Enthusiasm to work with mouse models is an asset Additional Information Why join UHN?In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN. Competitive offer packages Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/) Close access to Transit and UHN shuttle service A flexible work environment Opportunities for development and promotions within a large organization Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.) Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN’s attendance management program, to be eligible for consideration. All applications must be submitted before the posting close date. UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly. Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application. UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known. We thank all applicants for their interest, however, only those selected for further consideration will be contacted. Apply Now

Position Summary:A Postdoctoral Researcher position is available in the laboratory of Dr. Steven Chan at the Princess Margaret Cancer Centre. The Chan Laboratory studies the biology of acute myeloid leukemia (AML), leukemic stem cells, and clonal hematopoiesis (CH), with a strong translational focus on discovering and exploiting novel therapeutic vulnerabilities in pre-malignant and malignant myeloid cells. This project will define the genetic and synthetic-lethal interactions of high-risk clonal hematopoiesis mutations, including TP53 and spliceosome (splicing factor) mutations, that drive the progression of CH to myelodysplastic syndromes (MDS) and AML. The successful candidate will combine genetically engineered mouse models with genome-wide and focused CRISPR/Cas9 screens to uncover context-specific dependencies in mutant hematopoietic stem and progenitor cells. The ultimate goal is to nominate new strategies to intercept high-risk clonal hematopoiesis and to prevent or treat myeloid malignancy. Duties: Design, execute, and analyze pooled CRISPR/Cas9 screens (genome-wide and focused) in primary cells and cell-line models to identify synthetic-lethal and genetic interactions with high-risk CH mutations. Generate and characterize genetically engineered and transplantation mouse models of clonal hematopoiesis and myeloid malignancy, including colony management and in vivo experiments. Construct and produce lentiviral and/or retroviral vectors for gene knockout, knockdown, and overexpression. Perform a broad range of molecular and cellular biology techniques. E.g., molecular cloning, qPCR, Western blotting, flow cytometry and cell sorting, and primary hematopoietic cell culture. Analyze and integrate functional genomic and next-generation sequencing datasets in collaboration with the lab’s computational team. Maintain rigorous, well-documented records and adhere to laboratory quality, biosafety, and animal-care standards. Prepare manuscripts, figures, and presentations and present findings at lab meetings and scientific conferences. Contribute to grant writing and help conceive new research directions for the laboratory. Mentor and support graduate and undergraduate trainees as needed. Qualifications Awarded a PhD within the previous 5 years, or an MD or DDS within the previous 10 years, in molecular biology, cancer biology, hematology, genetics, or a related discipline Strong hands-on molecular biology expertise, including CRISPR/Cas9-based gene editing and screening – required. Experience designing and producing lentiviral (and/or retroviral) vectors – required. Demonstrated mouse handling and in vivo experimental experience (e.g., bone marrow transplantation, colony management, in vivo treatment studies) – required. Background in oncology, ideally in hematologic malignancies (AML, MDS, or clonal hematopoiesis) – strongly preferred. Flow cytometry and cell sorting, and primary hematopoietic cell culture – required. Familiarity with analysis of CRISPR-screen and/or NGS data (e.g., MAGeCK, DrugZ, R/Python) — an asset. A strong first-author publication record demonstrating productivity and technical rigour. Excellent problem-solving, organizational, and record-keeping skills. Strong written and verbal communication skills in English. Ability to work both independently and collaboratively within a multidisciplinary team. Additional Information Why join UHN? In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN. Competitive offer packages Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/) Close access to Transit and UHN shuttle service A flexible work environment Opportunities for development and promotions within a large organization Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.) Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN’s attendance management program, to be eligible for consideration. All applications must be submitted before the posting close date. UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly. Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application. UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known. We thank all applicants for their interest, however, only those selected for further consideration will be contacted.