Fixed-term

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them. The Institute is composed of the following four departments: The Department of Infectious Diseases The Department of Microbiology and Immunology The Department of Medical Biochemistry and Cell Biology The Department of Laboratory Medicine At present, the institute has about 315 employees and approximately 450 million SEK in total assets. Duties  Mitochondria contain their own genome that codes for several subunits of the respiratory chain. We have developed in vitro techniques to study mitochondrial DNA replication with purified proteins. We are now hiring a research assistant to study the function of the mitochondrial replication machinery in vivo and in vitro. In the planned work, the molecular consequences of disease-causing mutations in mitochondrial replication factors will be analyzed. The successful candidate will also identify small molecular compounds that influence mitochondrial DNA replication. The work will include expression, purification, and characterization of proteins in recombinant form. The successful applicant will also work with cloning, in vitro mutagenesis, and study DNA replication in a reconstituted system with radiolabelled nucleotides Qualifications  Bachelor’s degree in biomedical laboratory science or an equivalent relevant field. Documented experience with techniques/methods involved in the duties is required, particularly protein expression and protein purification. Previous studies of proteins involved in mitochondrial DNA replication are considered a strong merit. The work involves extensive collaboration, and therefore good teamwork and interpersonal skills are important. The applicant must have a good command of English, both spoken and written. Great emphasis will be placed on flexibility and the ability to collaborate effectively. Employment  The employment is limited (temporary) for 6 months and full-time with placement at the Institute of Biomedicine. First day of employment as agreed. Contact information for the post  If you have any questions about the position, please contact Professor Maria Falkenberg. Phone:   + 46 (0)31 7863444. E-mail: maria.falkenberg@medkem.gu.se Unions  Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives Application  To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  Applications must be received by: 2026-07-03  The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations. Salaries are set individually at the University. In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed. Apply Now

The Department of Physiology  is located at the Institute of Neuroscience and Physiology at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages. https://www.gu.se/en/doctoral-studies Duties    The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.     As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration.   Project description:   Background: The first years of life represent a critical developmental window during which both the intestine and brain undergo rapid maturation. During this period, the intestinal microbiota plays a central role in shaping intestinal and neurodevelopmental processes. Microbial colonization supports healthy development by promoting maturation of intestinal barrier function, immune tolerance, and gut–brain communication, but when dysregulated, it may contribute to disease, including chronic intestinal inflammation and impaired neurodevelopment. Despite the recognized importance of microbiota-driven signaling in postnatal development, the mechanisms that distinguish beneficial from detrimental host–microbe interactions remain poorly understood. In the intestine, goblet cells produce a mucus barrier that physically separates the microbiota from the epithelium, thereby limiting host–microbe interactions. This barrier undergoes rapid postnatal maturation and is a key regulator of intestinal homeostasis in adulthood. However, its role during early life—particularly in shaping immune maturation and systemic developmental processes—remains incompletely understood. Purpose/Objective: The main objective of this doctoral project is to define the role of goblet cells and mucus in regulating postnatal intestinal and neurodevelopment. The doctoral student will use mouse models with an impaired mucus barrier to investigate the role of mucus in regulating the gut–brain axis, with a focus on immune and neuronal maturation.Methods: Core methodologies include immunohistochemistry, flow cytometry, proteomics, RNA sequencing, and RNAscope, alongside in vivo experiments in mice. The student will join the Gustafsson Lab at the Department of Physiology, which is also part of the Mucin Biology Groups—a collaborative research environment focused on goblet cell and mucus biology. Practical experience with laboratory animals is desirable. Experience in physiology, mucosal immunology, and goblet cell and mucus biology, as well as relevant techniques such as confocal microscopy, flow cytometry, and transcriptional data analysis, will be considered merits. Eligibility    Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject.   The general eligibility requirements for doctoral studies are:     having completed a degree at second-cycle level, or the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or   the acquisition of equivalent knowledge in some other way, either in Sweden or abroad.  Specific entry requirements for this subject, according to the general syllabus, are: having completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies Assessment criteria    The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields– experience of scientific theory and relevant research methodology– scientific analysis and presentation verified through an academic paper, degree project, scientificjournals or the like. Admission and employment    Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Physiology. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Neuroscience and Physiology require physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the institute has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies. Contact information  For more information about the project please contact the project supervisor,Jenny Gustafsson, Institute of Neuroscience and Physiology,e-mail: jenny.gustafsson@gu.se Unions  Union representatives at the University of Gothenburg can be found here:   https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande    Application    You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal.    It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline.    You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier.   For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/ Applications must be received by: 2026-07-01 Information for International Applicants  Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. Doctoral position in Medical Science    Project title: Interferon-stimulated proteins in Diffuse Large B-cell lymphoma (DLBCL) – prognosis, function and therapy The Department of Internal Medicine and Clinical Nutrition  is located at the Institute of Medicine at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages. https://www.gu.se/en/doctoral-studies Duties    The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.     As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration.   Project description:  Despite advances in both treatment and genetic classification of diffuse large B-cell lymphoma (DLBCL), around 25% of patients still die from their disease. DLBCL is a heterogeneous tumor where both the malignant clone and the tumor microenvironment contribute to the variable clinical picture. However, the complexity can probably not only be explained by genetic changes, and it is also difficult to predict whether such changes really affect protein expression and thus the phenotype of the tumor cell. By parallel studies on global protein expression, RNA-sequencing and digital image analysis of immunohistochemical staining in tumor tissue from DLBCL patients, we have found that overexpression of interferon-stimulated genes/proteins (especially belonging to the PYHIN group), appears to affect both prognosis and response to treatment. After performing further in vitro studies in DLBCL cell lines, our data also indicate a functional role.Interferon-stimulated genes (ISGs) play an important role primarily in antiviral immunity, but in recent years it has become increasingly evident that they can also affect immunosuppressive mechanisms in various forms of cancer and then induce both tumor progression and treatment resistance. Their significance in DLBCL is so far unknown.The main purpose of the project is to test the hypothesis if interferon-stimulated proteins, primarily from the PYHIN group, influence treatment resistance in DLBCL and if they could be of therapeutic potential. The specific aims are to:1. study the functional role of interferon-stimulated genes/proteins in DLBCL cell lines,2. investigate the therapeutic effect of blocking/down-regulating/degrading interferon-stimulated genes/proteins, as proof-of-concept, in vitro and in vivo using DLBCL mouse models. Documented experience of experimental studies in cell culture with CRISPR technology and flow cytometry is an advantage, as is experience of RNA/protein preparation, RNA sequencing and bioinformatics. Furthermore, experience of working with mouse cancer models is desirable. Eligibility    Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject.   The general eligibility requirements for doctoral studies are:     having completed a degree at second-cycle level, or the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or   the acquisition of equivalent knowledge in some other way, either in Sweden or abroad.  Specific entry requirements for this subject, according to the general syllabus, are: having completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies Assessment criteria    The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields– experience of scientific theory and relevant research methodology– scientific analysis and presentation verified through an academic paper, degree project, scientificjournals or the like. Admission and employment    Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Medicine, the Department of Internal Medicine and Clinical Nutrition. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Medicine require physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the institute has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies. Contact information  For more information about the project please contact the project supervisor,Per-Ola Andersson , Institute of Medicine,e-mail: per-ola.andersson@medic.gu.se Unions  Union representatives at the University of Gothenburg can be found here:   https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande    Application    You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal.    It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline.    You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6

The Department of laboratory medicine is located at the Institute of Biomedicine  at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages. https://www.gu.se/en/doctoral-studies Duties    The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.     As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration.   Project description:  Acute myeloid leukemia is the most common form of acute leukemia in adults, but it can also affect children. Treatment consists of chemotherapy, sometimes combined with allogeneic stem cell transplantation. Despite improved treatment outcomes, the risk of relapse remains high, particularly among adults, where more than half of patients relapse within 1–3 years. Relapse is often caused by residual leukemic cells remaining in the bone marrow, referred to as measurable residual disease (MRD), making MRD analysis central for treatment decisions and early detection of relapse. To enable molecular MRD analysis in a larger proportion of patients than is currently possible, our research group has developed ultra-high sensitivity next-generation sequencing (UHS-NGS), a DNA-based method that can be designed for both common and patient-specific mutations. The overall aim of this PhD project is to investigate how UHS-NGS can be used for MRD detection in order to contribute to improved patient management and increased long-term survival in acute myeloid leukemia. The subprojects are based on clinical studies in which UHS-NGS is performed retrospectively or prospectively on blood and/or bone marrow samples. The doctoral student will participate in the administration and coordination of clinical studies and perform UHS-NGS and whole-genome analyses on study samples. The project involves data collection and communication in Swedish. Practical experience in deep sequencing and hematological research is considered meritorious. Eligibility    Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject.   The general eligibility requirements for doctoral studies are:     having completed a degree at second-cycle level, or the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or   the acquisition of equivalent knowledge in some other way, either in Sweden or abroad.  Specific entry requirements for this subject, according to the general syllabus, are: having completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies Assessment criteria    The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields– experience of scientific theory and relevant research methodology– scientific analysis and presentation verified through an academic paper, degree project, scientificjournals or the like. Admission and employment    Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Biomedicine, Department of laboratory medicine. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the institute of Biomedicine require physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the institute has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies. Contact information  For more information about the project please contact the project supervisor,Linda Fogelstrand, Institute of Biomedicine,e-mail: linda.fogelstrand@clinchem.gu.se Unions  Union representatives at the University of Gothenburg can be found here:   https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande    Application    You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal.    It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline.    You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier.   For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/ Applications must be received by: 2026-06-23 Information for International Applicants  Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:  https://www.gu.se/en/about-the-university/welcome-services https://www.movetogothenburg.com/  The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations. Salaries are set individually at the University. In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment

The Department of Psychiatry and Neurochemistry is located at the Institute of Neuroscience and Physiology at the Faculty of Medicine at Sahlgrenska Academy, University of Gothenburg. General information about being a doctoral student at the University of Gothenburg can be found on the university’s doctoral student pages. https://www.gu.se/en/doctoral-studies Duties    The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies Doctoral studies comprises four years of full-time study, and leads to a doctoral degree.     As part of your employment as a doctoral student, you may have departmental duties corresponding to up to 20 % of full-time employment, distributed throughout your study period, and result in a corresponding extension of the studies. Departmental duties usually consist of teaching at first- and second-cycle levels, but may also include research and administration.   Project description:  The tau protein undergoes extensive post-translational modifications, including phosphorylation and proteolytic cleavage, giving rise to a wide range of molecular forms. Several of these forms are altered in Alzheimer’s disease and other tauopathies and are therefore of great interest as biomarkers. Specifically, phosphorylated tau species in plasma, such as pTau217, have demonstrated very high diagnostic accuracy for Alzheimer’s disease. At the same time, significant challenges remain regarding standardization and comparability between different analytical methods. Mass spectrometry has enabled detailed analysis of tau in cerebrospinal fluid and plasma, but low concentrations have previously limited its applicability. The new Orbitrap Astral Zoom technology offers greatly improved sensitivity and enables analysis of very low levels of tau in small sample volumes. Purpose/Objectives The overall aim of the project is to develop and apply ultra-sensitive mass spectrometry-based methods for characterization of tau in plasma and cerebrospinal fluid. The project aims to: increase understanding of tau-related disease processes,identify biomarkers for different tauopathies,develop reference methods for standardization of clinical biomarkers, particularly plasma pTau217. Implementation The project includes method development and analysis of clinical samples from patients with Alzheimer’s disease and other tauopathies. The work includes development of advanced mass spectrometry methods on the Orbitrap/Astral platform, deep profiling of tau species in biological fluids, and development and validation of an isotope dilution mass spectrometry-based reference method for plasma pTau217. The project also includes evaluation of biomarker diagnostic performance and comparison with established immunoassays in large clinical cohorts.   Eligibility    Doctoral education requires general eligibility and, where appropriate, specific eligibility as set out in the general syllabus for the subject.   The general eligibility requirements for doctoral studies are:     having completed a degree at second-cycle level, or the fulfilment of course requirements totalling at least 240 credits, of which at least 60 credits must be at second-cycle level, or   the acquisition of equivalent knowledge in some other way, either in Sweden or abroad.  Specific entry requirements for this subject, according to the general syllabus, are: having completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies Assessment criteria    The selection of applicants who meet the basic and specific eligibility requirements will be based on the ability to assimilate the doctoral studies. The assessment shall attach particular importance to documented qualifications for: – specific knowledge and skills within the subject area and related research fields– experience of scientific theory and relevant research methodology– scientific analysis and presentation verified through an academic paper, degree project, scientificjournals or the like. Admission and employment    Once you have been admitted to doctoral studies, you will be employed as a doctoral student at the University of Gothenburg. The provisions for employment as a doctoral student can be found in ordinance SFS 1993:100. Initial employment as a doctoral student may apply for a maximum of one year, and may be renewed by a maximum of two years at a time. A doctoral student may be employed as a doctoral student for a maximum of eight years, but the total period of employment may not be longer than the equivalent of full-time education at doctoral level for four years. Location: Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry. Extent: 100%. First day of employment: as agreed. The University applies a local agreement on salaries for doctoral students. Please note, doctoral studies at the Institute of Neuroscience and Physiology require physical presence to conduct the studies. If the admitted applicant needs a residence permit for higher education to pursue studies in Sweden, the institute has the right to revoke the admission decision if the applicant cannot present a valid residence permit no later than at the start of the studies. Contact information  For more information about the project please contact the project supervisor,Johan Gobom, Institute of Institute of Neuroscience and Physiology,e-mail: johan.gobom@neuro.gu.se Unions  Union representatives at the University of Gothenburg can be found here:   https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande    Application    You can apply to be admitted to doctoral education via the University of Gothenburg’s recruitment portal.    It is your responsibility to ensure that the application is complete as per this notice, and that the University receives it by the final application deadline.    You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier.   For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/ Applications must be received by: 2026-06-23 Information for International Applicants  Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:  https://www.gu.se/en/about-the-university/welcome-services https://www.movetogothenburg.com/  The University works actively to achieve a working environment with equal conditions, and values the qualities that

£36,636 rising to £39,906 Full Time, Fixed Term – Researcher The Centre for Functional Genomics is recruiting a fixed-term Postdoctoral Researcher in Functional Genomics for 18 months starting as soon as possible.   The overall purpose of the role is to lead an ambitious, BBSRC-funded project which aims to establish a biological resource to enable the in-depth study of transcription factor function in Drosophila by generating and injecting a collection of plasmids to allow the CRISPR-mediated endogenous tagging of all Drosophila transcription factors with an exchangeable epitope.   You will be responsible for: Collaborating closely with the line manager and other team members on the research project to establish a collection of transgenic Drosophila lines with tagged transcription factors Designing transgenesis constructs and help with their molecular cloning and helping to generate transgenic fly strains Performing immunostains on different Drosophila tissues and confocal imaging of the samples to analyse transcription factor expression patterns Performing genome-wide transcription factor binding site analysis using CUT& RUN sequencing Populating and maintaining a database with imaging and binding profile data Assisting with the preparation of manuscripts for publication and presenting data at conferences As Postdoctoral Researcher in Functional Genomics you should have: PhD in Genetics, Developmental Biology, Molecular Biology, Biochemistry or equivalent Experience with general molecular biology methods, especially molecular cloning Experience with the preparation of scientific publications Good knowledge of Drosophila biology, eukaryotic gene regulation, CRISPR-mediated transgenesis Experience in functional genomics techniques such as ChIP-seq and/or CUT& RUN sequencing and the analysis of functional genomics data Experience in immunostaining and confocal microscopy As one of the largest employers in Oxford we pride ourselves in the great experience we offer our staff. You’ll be joining a friendly, professional environment where every member of staff is recognised as important to the success of Oxford Brookes University.  To find out more about the benefits of working for Oxford Brookes please visit: www.brookes.ac.uk/job-vacancies/working-at-brookes.   Equality, Diversity and Inclusion   At Oxford Brookes, inclusivity is one of our five guiding principles: we take positive steps to create an environment in which we celebrate, value and provide equal opportunity to all. We are committed to recruiting from the widest possible pool and welcome applications from all suitably qualified candidates who embrace our values, regardless of their background. As a Disability Confident Employer we guarantee to interview any disabled applicant who meets the essential selection criteria.   Please note, due to the volume of applications, we are not able to provide feedback to applicants that are not shortlisted.   To email the post of Post Doctoral Researcher in Functional Genomics to a friend copy and paste link below: https://my.corehr.com/pls/oburecruit/erq_jobspec_details_form.jobspec?p_id=193486 Click on the link(s) below to view documents Person Specification.pdf A Job Description.pdf To view the official job advertisement, visit the application url and search for the keyword “Functional Genomics”. Apply Now