Fixed-term

Project Overview Why do some organisms age more gracefully than others? Mitochondria—the cell’s powerhouses—lie at the centre of this mystery. These tiny organelles generate most of the cell’s energy, but they also accumulate damage with age and are implicated in age-related diseases. Paradoxically, studies in multiple species reveal that reducing mitochondrial activity can actually extend lifespan. How can less energy make an organism live longer? Our laboratory has recently resolved part of this paradox. Using Drosophila melanogaster, we discovered that flies are highly sensitive to mitochondrial dysfunction during development but remarkably resilient in adulthood. A mild (10%) reduction in mitochondrial function during larval or pupal stages can halve adult lifespan, whereas a severe (75%) reduction in adulthood has no detrimental effects—and can even promote longevity. These results suggest that mitochondria are not equally essential throughout life; instead, their timing of activity is what matters most. Project Aim This PhD will determine when mitochondria are essential for ensuring a long and healthy adult life. The student will investigate which developmental stages require optimal mitochondrial function and whether these “critical windows” vary between tissues such as brain, muscle, gut, and fat body. Understanding this timing will help redefine how we view mitochondrial ageing and could ultimately inform strategies to promote healthspan across species. Approach and Training The student will use advanced Drosophila genetics (GAL4/GAL80/ GeneSwitch and QF2/QS systems) to control mitochondrial activity precisely in time and space. They will learn to combine genetic, molecular, and physiological techniques, including: Generating and characterising new fly lines using RNAi and CRISPR/Cas9. Measuring mitochondrial respiration through high-resolution respirometry. Assessing lifespan and mortality through Gompertz modelling. Performing tissue-specific imaging (confocal microscopy, TUNEL assays). Analysing large transcriptomics and proteomics datasets. This training will provide a strong foundation in molecular biology, bioenergetics, data analysis, and scientific communication—skills highly valued across academia and industry. Supervision and Environment The project will be led by Prof. Alberto Sanz, an international expert in mitochondrial biology and ageing. The student will work within a vibrant, interdisciplinary team that includes molecular biologists, chemist, and computational scientists. The lab has extensive experience in Drosophila models of mitochondrial disease and lifespan regulation, with a proven record of mentoring successful PhD students and postdocs. Who Should Apply We seek a highly motivated candidate with a strong background in biology, biochemistry, genetics, or a related field. Curiosity, independence, and enthusiasm for understanding the fundamental biology of ageing are essential. Previous experience with molecular or fly genetics is advantageous but not required—full training will be provided. Why This Project? This is an exceptional opportunity to tackle one of biology’s oldest questions—what determines how long we live—from an entirely new angle. By revealing when mitochondria matter most, this research could reshape our understanding of ageing and inspire novel strategies for promoting health throughout life. Funding Notes The studentship is supported by a grant from the Leverhulme Trust that has budget to cover stipend and student fees. The grant also includes money for consumables.   Apply Now

Job Purpose To contribute / make a leading contribution to an MRC Programme grant entitled “Targeting the primary afferent drivers of neuropathic pain,” working with Dr Greg Weir and his wider neurobiology of pain lab. Our laboratory aims to define the pathological changes that occur in the nervous system following injury and that give rise to neuropathic pain. We use this fundamental understanding to develop innovative strategies to reverse these changes and ultimately treat pain. This project is a close collaboration between our group in Glasgow and the laboratory of Professor David Bennett at the University of Oxford. The postholder will have access to a wide range of cutting-edge experimental approaches, including opto- and chemogenetics, omics technologies, and stem cell culture, to interrogate both in vivo and in vitro systems. They will be fully supported in developing their scientific career within the inclusive and collaborative environment of the wider Spinal Cord Group. The successful candidate will also be expected to contribute to the formulation and submission of research publications and research proposals as well as help manage and direct this complex and challenging project/disciplinary area as opportunities allow. Main Duties and Responsibilities Perform the following activities in conjunction with and under the guidance of the Principal/Co Investigator: 1.  Plan and conduct assigned research individually or jointly in accordance with the project deliverables and project/group/School/College research strategy. 2.  Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate. 3.  Develop and enhance your research profile and reputation and that of The University of Glasgow/School/Research Group, including contributing to publications of international quality in high profile/quality refereed publications, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem. 4.  Contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile. 5.  Contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research. 6.  Collaborate with colleagues and participate in team/ group/ meetings/ seminars/ workshops across the research Group/School/College/University and wider community. 7.  Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development. 8.  Perform administrative tasks related to the activities of the research group and School, including budgets/expenditure. 9.  Contribute as appropriate to teaching activities (e.g. demonstrating, etc) and associated administration, as may be assigned through the School in consultation with your line manager. 10.  Keep up to date with current knowledge and recent advances in the field/discipline. 11.  Engage in personal, professional and career development, to enhance both specialist and transferable skills in accordance with desired career trajectory. 12.  Undertake any other reasonable duties as required by your line manager and the Head of School. 13.  Contribute to the enhancement of the University’s international profile in line with University strategy. For appointment at Grade 7 14.  Take a leading role in the planning and conduct of assigned research individually or jointly in accordance with the project deliverables and project/group/School/College research strategy. 15.  Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate. 16.  Establish and maintain your research profile and reputation and that of the University of Glasgow/School/Research Group/area, including establishing and sustaining a track record of independent and joint publications of international quality, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem. 17.  Survey the research literature and environment, understand the research challenges associated with the project & subject area, and develop/implement a suitable research strategy to deliver project/area requirements and opportunities. 18.  Presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research and/or impact profile. 19.  Take a leading role in the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research and impact. 20.  Take a leading role in developing and maintaining collaborations with colleagues across the research group/area/School/College/University and wider community (e.g. academic and industrial partners). 21.  Take a leading role in team/group meetings/seminars/workshops and School research group/area activities to enhance the wider knowledge, outputs and culture of the School/College. 22.  Take the lead in the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development. Knowledge, Qualifications, Skills and Experience Knowledge/Qualifications Essential: A1   SCQF level 10 (Honours Degree). May be working towards post-graduate qualification such as a Masters (SCQF level 11) or PhD (SCQF level 12) in Neuroscience or another relevant subject. OR equivalent professional qualifications in relevant academic / research discipline, and experience of personal development in a similar role. A2   A comprehensive and up-to-date knowledge of current issues and future directions within the field of somatosensation and pain, or related neuroscience subjects A3  Well-developed working knowledge of neuroscience research methods, technical models, equipment and techniques relevant to the study of somatosensation and pain For appointment at Grade 7 A4   SCQF level 12 (PhD) qualification, plus track record of emerging independence within a research/professional environment, or alternatively possess professional qualifications and experience equivalent to PhD level plus the requisite experience, with experience in Neuroscience, Pain Biology or Molecular Biology. Skills  Essential: C1 Research creativity and cross-discipline collaborative ability as appropriate C2 Excellent communication skills (oral and written), including public presentations and ability to communicate complex data/concepts clearly and concisely C3 Excellent interpersonal skills including team working and a collegiate approach C4 Appropriate workload/time/project/budget/people management skills C5 Extensive IT and data analysis/interpretation skills as appropriate C6 Self-motivation, initiative and independent thought/working C7 Problem solving skills including a flexible and pragmatic approach For appointment at grade 7 C8  Ability to communicate material of a specialist or highly technical nature and

Background The Department of Cancer and Genomic Sciences at the University of Birmingham is seeking an exceptional candidate for a research position in the Morris lab to undertake fundamental research in DNA replication and DNA damage and repair. The post holder will investigate how replication fork transitions are regulated and balanced. They will create and contribute to knowledge by addressing how critical transition points in DNA replication stalling are controlled and relate to topological differences in DNA using cell biological approaches, and advanced microscopy and/ or biophysical approaches. The successful applicant will join a vibrant laboratory with opportunities for personal and professional development within research leadership, teaching and fellowship mentoring. The Department of Cancer and Genomics is a diverse Cancer Research Centre, containing one of the largest Cancer Clinical Trials Units and high-profile DNA repair and replication research groups.  The position is supported by a Wellcome Trust Discovery Award.  Role Summary To design, perform and record experiments that inform this area, including developing new methodologies. Work within specified research grants and projects and contribute to writing bids. Operate within area of specialism and develop ideas beyond that area. Analyse and interpret research findings and results. Contribute to generating funding. Support other members of the research group and work with lab members towards publications and long-term projects.  Main Duties The responsibilities may include some but not necessarily all of the responsibilities outlined below. Develop research objectives and proposals for own or joint research, with assistance of a mentor if required. Bring the ability to invent new, or adapt existing, methodologies. Contribute to the development of others in the research team, providing guidance, as required, to support staff and any students who may be assisting with the research.  Contribute to writing bids for research funding. Analyse and interpret data, recommend next steps within the context of current literature. Apply knowledge in a way which develops new intellectual understanding. Keep excellent contemporaneous notes and records. Disseminate research findings for publication, research seminars etc. Supervise students on research related work and provide guidance to PhD students, and more junior members of staff where appropriate to the discipline. Contribute to developing new models, techniques and methods. Undertake management/administration and day-to-day laboratory tasks needed for research. Contribute to Departmental/School research-related activities and research-related administration. Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader. Collect research data; this may be through a variety of research methods, such as scientific experimentation, literature reviews, and research interviews.  Present research outputs, including drafting academic publications or parts thereof, for example at seminars and as posters.  Deal with problems that may affect the achievement of research objectives and deadlines, such as those for publication or grant deadlines. Promotes equality and values diversity acting as a role model and fostering an inclusive and kind working culture. Person Specification First degree in area of specialism and normally, a PhD (or near to completion) relevant to research area or equivalent qualifications. Demonstrable research experience of, or detailed knowledge of, mammalian DNA replication and/or DNA repair, which should include techniques such as DNA fibre analysis, IPOND or transmission electron microscopy. Demonstrable productivity including publications or preprints. High level analytical capability. Evidence of having developed or invented new methods and the ability to learn new approaches outside of current expertise. Ability to communicate complex information clearly. Fluency in relevant models, techniques or methods and ability to contribute to developing new ones. Ability to assess resource requirements and use resources effectively. Understanding of and ability to contribute to broader management/administration processes. Ability to contribute to the planning and organising of the research programme and/or specific research project. The ability to co-ordinate own work with others to avoid conflict, duplication of effort and to promote efficiency. Have knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day-to-day activity in own area with those with protected characteristics are treated equally and fairly. Further particulars can be found here Informal enquiries to Jo Morris, email: j.morris.3@bham.ac.uk  Use of AI in applications: We want to understand your genuine interest in the role and for the written elements of your application to accurately reflect your own communication style. Applications that rely too heavily on AI tools can appear generic and lack the detail we need to assess your skills and experience. Such applications will unlikely be progressed to interview.   Apply Now

The University           At Durham University, we are proud of our people, because they are at the heart of our globally outstanding institution, which is a key part of our local community.  We inspire our people to do extraordinary things and we invite you to join our fantastic team.          Across the University, we have a huge variety of roles and responsibilities, which together make us one large and successful community. Whether you are at the very start, middle or end of your career, there is a role for you. We believe everyone has their own unique skills to offer.          At the University we promote and actively champion equality, diversity and inclusion. It is crucial that everyone can be themselves and can flourish in an environment where everyone respects each other and is treated fairly. We want our people and wider community to feel happy, secure and proud to be a part of Durham. We are looking for the same values in you.           We welcome and encourage applications from members of groups who are under-represented in our work force including people with disabilities, women and black, Asian and minority ethnic communities.  For more information on our EDI strategy and values click here       The Role and Department       You will join the InsectNeuroLab in the Department of Biosciences, Durham University (http://insectneurolab.com/ ) that uses mosquitoes and other insects to study sensory neuroscience and sensory ecology. You will be responsible for the maintenance on mosquito and fly stocks and the insectary space. You will also contribute to ongoing experimental work. The role requires experience in research work, ideally with insects, knowledge of relevant Health and Safety regulations and be able to work on set tasks as part of a team. The role involves a diverse array of activities (e.g. maintaining mosquito colonies, maintaining insectary clean and organised, assisting in setting up mosquito crosses, assisting in the experimental work of lab members, liaising with and coordinating work with lab members, ensuring there is sufficient stock of necessary laboratory supplies, participation in lab meetings and other meetings/activities with the team, participation in research experiments, etc). This is a permanent/part-time role (14 hours per week/0.4FTE), the successful candidate can potentially start working from 1st July 2026. Further information about the role and the responsibilities is at the bottom of this job description.     Working at Durham          A competitive salary is only one part of the many fantastic benefits you will receive if you join the University: ·         You’ll receive 27 days annual leave per year in addition to 8 public holidays and 4 customary days per year – a total of 39 days (Pro Rata). ·         No matter how you travel to work, we have you covered.  We have parking across campus, a cycle to work scheme which helps you to buy a bike and discount with local bus and train companies.  ·         You can access exclusive discounts via our benefits portal including money off at supermarkets, high street retailers, IT products such as Apple, eating out and days out at various attractions.   ·         Our on-site nursery is rated Outstanding by Ofsted, and you can access holiday camps for children aged 5-16.  ·         We provide wide-ranging health and wellbeing support including discounted membership for our state-of-the-art sport and gym facilities and access to a 24-7 Employee Assistance Programme.    ·         We offer all staff the opportunity to take part in volunteering activities to make a difference to the local community.   ·         Our family friendly policies, including maternity and adoption leave, are among the most generous in the higher education sector (and likely above and beyond many employers).    ·         If you are keen on advancing in your role or career, we have a genuine passion for developing our colleagues from qualifications to IT skills, courses and apprenticeships.   ·         We offer generous pension schemes with varying contribution amounts to help you plan for your future.     Discover more about our total rewards and benefits package here.  What you need to demonstrate when you apply To be considered for this role, here are the skills/experience we’re looking for: Qualifications/Experience 1.    Five GCSEs at least Grade C or level four (or equivalent) including English Language and Mathematics or equivalent experience. 2.    Science qualification (Biology, Animal Science, Zoology, Psychology, Chemistry, Botany or equivalent) and an understanding of how academic research works. 3.    Experience of working in a technical environment setting up resources, tools and equipment to meet teaching and research outputs or having relevant qualifications for the role.  4.    Experience of working in a team. 5.    Experience of managing time to meet deadlines.  Skills/Abilities/Knowledge 6.    Good spoken and written communication skills. 7.    Good digital skills including experience in using digital devices and apps including the internet, email, digital communication tools, Microsoft 365 applications, digital booking systems. 8.    Committed to training/continuing professional development. 9.    Ability to solve problems as part of a team and resolve straightforward issues. 10.  Ability to provide advice and guidance to a range of colleagues and customers. 11.  Patience and attention to details 12.  Ability to perform set tasks to completion 13.  Ability to work cooperatively as part of a team 14.  A “can do” attitude and a willingness to expand their knowledge 15.  Ability to maintain working environment by monitoring usage and re-ordering consumables 16.  An understanding of the needs to work within Health and Safety Policies, and an understanding of the essentials of good laboratory practice  Desirable Criteria 17.  Undergraduate or higher science degree 18.  Experience of working in a research lab 19.  Interest in insects and/or neuroscience 20.  Knowledge of laboratory-based biological techniques 21.  Desire to learn and to use this position as a stepping stone for future science-based career  How to Apply            We prefer to receive applications online. When you apply you need to submit a CV and/or a statement that tells us your experience and gives examples of how you meet the criteria above and/or submit the application form and include the information within the form.        We will update you about your application at various points throughout the selection process, via automated emails from our e-recruitment system. Please check your spam/junk folder periodically to make sure you have not missed any of our updates.          Who to contact for more information          If you would like to have a chat

Details The surface of human skin is colonized by millions of microorganisms, forming a complex microbial community. The skin, together with its microbiota, is continuously exposed to environmental factors, including solar radiation, which exerts both short-term and long-term effects on skin cells. Although numerous studies have investigated the impact of ultraviolet radiation (UVR) on cutaneous tissues, there remains limited data regarding the influence of UVR on the skin microbiome and its subsequent effects on skin physiology. Previous work in the O’Neill laboratory has identified that model polymicrobial community (PMC) modifies the secretion of cytokines from keratinocyte monolayers following a single dose of solar simulated radiation (SSR) (Serrage et al., (2026) Appl Environ Microbio, in press), with specific strains that elicit particular responses. In a separate study, the laboratory has also showed that irradiated bacteria have altered metabolite profile that resulted in improved keratinocyte barrier function (Mercer et al., (2026), Appl. Environ. Microbiol In press). These data have led to the following hypotheses: The skin microbiome influences how skin responds to ultraviolet radiation. Certain strains within the microbiome may confer protective benefits and support more effective recovery pathways in skin following UVR exposure.   Thus far, the work in O’Neill lab has been confined to human keratinocyte cultures for such studies. This project will utilize explant human skin acquired from elective plastic surgery procedures, which the lab has experience working with (El Chami et al. (2021) Br J Dermatol, 184 (3): 482). The objectives of this project are: To quantify the impact of a single dose of SSR on a model polymicrobial community artificially inoculated on ex vivo human skin. To compare the transcriptome and secretome of ex vivo human skin to irradiation with and without the PMC. To examine whether the microbiome influences potential pathway(s) for enhanced recovery in irradiated skin. Methodologies: Establishing Single strain and Polymicrobial community on ex vivo skin, solar simulator radiation exposure, and quantify microbial recovery post-incubation. Pre- and post-irradiation transcriptome and secretome profile of microbial community and skin using advanced measurement and bioinformatic tools Validation of identified markers using tools such as QPCR, Immunostaining, ELISA, etc. Further investigate identified recovery pathways and role of single species and/or community using colonization models. Eligibility   Applicants must hold, or be expected to achieve, a first or high upper second-class undergraduate honours degree or equivalent (for example BA, BSc, MSci) or a Masters degree in a relevant subject. How to Apply   Applications should be made using the following link: https://forms.cloud.microsoft/e/mq7MsbmgqM [forms.cloud.microsoft] Deadline 5pm Monday 20 July 2026. Equality, Diversity and Inclusion    Equality, diversity and inclusion is fundamental to the success of The University of Manchester, and is at the heart of all of our activities. The full Equality, diversity and inclusion statement can be found on the website: Equality, diversity and inclusion (EDI | Postgraduate Research | Biology, Medicine and Health | University of Manchester  Funding Notes This studentship is jointly funded by Unilever and The University of Manchester. Studentship funding is for a duration of four years to commence in September 2026 and covers UK tuition fees and an annual stipend (UKRI level).  References References:Serrage et al., (2026) Appl Environ Microbio, in press Mercer et al., (2026), Appl. Environ. Microbiol In press Apply Now

We are seeking a motivated and collaborative individual to join our team as a Postdoctoral Research Associate within RISE (Reducing Immune Stress from Excess Cytokine Release in Advanced Therapies), an interdisciplinary MRC‑funded programme based in the Faculty of Biology, Medicine and Health. This role offers an exciting opportunity to contribute to cutting‑edge translational research aimed at improving the safety and efficacy of advanced therapies, including CAR‑T cell treatments. You will play a leading role in research investigating the pathogenesis of cytokine release syndrome (CRS) using advanced spatial profiling technologies, working closely with academic and clinical collaborators. This is a full‑time, fixed‑term role for four years from September 2026, based at the University of Manchester. You will be responsible for: Designing and delivering research using Co‑Detection by Indexing (CODEX) for high‑dimensional multiplexed imaging of bone marrow tissue Optimising, implementing and analysing CODEX workflows on patient‑derived samples Analysing and interpreting complex spatial and imaging datasets Publishing research outputs in peer‑reviewed journals and contributing to grant applications Working collaboratively within a multidisciplinary research team across the RISE programme We welcome candidates who bring diverse perspectives, experiences, and approaches to their work. About YouWe encourage applications from individuals with a wide range of backgrounds and experiences. You should demonstrate: Essential Criteria: A PhD (or close to completion) in haematology, immunology, cancer biology or a closely related discipline Experience handling and processing human tissue samples, including histological or bone marrow specimens Experience with multiplex imaging, immunohistochemistry, immunofluorescence or spatial biology approaches Experience analysing complex biological datasets, including image‑based data Excellent communication, organisational and collaborative working skills Desirable Criteria: Experience with CODEX or other high‑parameter spatial imaging platforms Knowledge of CRS, CAR‑T cell therapy or immune‑related adverse events Experience integrating imaging, molecular and clinical datasets Experience contributing to grant applications or ethics submissions We value curiosity, rigour and a commitment to translational research as much as formal qualifications. Our benefits include:• Generous employer pension contribution• 29 days annual leave plus bank holidays, along with Christmas closure• Access to world‑class research facilities and professional development opportunities For more information, please seehttps://www.manchester.ac.uk/connect/jobs/benefits-working-here/.You can also find information on Flexible and Hybrid working here:https://www.staffnet.manchester.ac.uk/people/current-staff/flexible-and-hybrid-working/. We are an open place of enquiry and challenge. We embrace and celebrate difference, diversity and debate, and we pride ourselves on being a place of education, learning and community. Find out more from our Freedom of Speech Policy:https://www.staffnet.manchester.ac.uk/news/display/?id=32905. Enquiries about the role, shortlisting and interviewsName: Dr Simona Valletta / Dr Holly BuendiaEmail Address: simona.valletta@manchester.ac.uk / holly.buendia@manchester.ac.uk General enquiries and administrative supportrecruitmentservices.people@manchester.ac.uk Technical and job portal supporthttps://jobseekersupport.jobtrain.co.uk/support/home Applications close at midnight on the closing date.Further particulars (with person specification) linked below. Apply Now

About Us King’s College London is one of the world’s leading research-intensive universities, renowned for excellence in health and life sciences and its close integration with clinical practice through King’s Health Partners. The Comprehensive Cancer Centre (CCC) at King’s College London is the academic arm of one of Europe’s leading cancer centres, bringing together world‑class clinical services delivered by NHS partners with cutting‑edge research and education to improve outcomes for cancer patients in South East London and beyond. The Centre has a strong and diverse research portfolio, supported by major strategic investments including the Cancer Research UK City of London Centre, CRUK RadNet, the KHP Experimental Cancer Medicine Centre, PharosAI, and the Breast Cancer Now Research Unit. Led by Professor Sheila Singh, Head of the Comprehensive Cancer Centre and joint Head of the School of Cancer and Pharmaceutical Sciences, the CCC is also committed to training the next generation of researchers, supporting over 80 PhD students and delivering a highly successful MRes in Translational Cancer Medicine. The three types of tumours studied by Dr. Singh’s lab are glioblastoma, medulloblastoma and brain metastases. The lab employs a stem cell biology framework to the study of these cancers to identify and target the molecular mechanisms responsible for their development. Their goal is to determine which treatment refractory cells are leading to relapse and recurrence in patients. Ultimately, Dr. Singh’s goal is to be able to take more targeted and effective therapies back to the clinic. To ensure that all of their findings have the potential to be clinically relevant, the Singh lab has cultivated a specialty in developing pre-clinical models and are steadfast in their commitment to working with brain tumour samples direct from human patients. About The Role The post holder will play a significant role in Professor Singh’s laboratory, its establishment at King’s College London and ongoing management, overseeing the team’s research work. Working closely with the laboratory’s Technical Manager they are responsible for the induction of staff, students and visitors working in the laboratory, in particular the use of protocols, of equipment and techniques to ensure that there is adherence to these and good laboratory practice (including biosafety) to give assurance that the research findings are robust and replicable. The post holder develop comprehensive experimental project plans (timelines, milestones, resource allocation and budget requirements) and is responsible for the day-to-day delivery of Professor Singh’s research programme. They will guiding the wider team when problems arise. Once established in the post, the post holder is expected to manage other members of the laboratory team. They will contribute to the development of the laboratory, its strategic direction and will co-author research papers and develop research funding applications. They will be instrumental in setting up new grants and projects – including seeking ethics approval – and working with the laboratory’s Technical Manager to manage on a day-to-day basis the resources used by the laboratory. They will represent the laboratory, including at meetings with industry contracts, collaborator/partners and the public, as well as to expert groups, such as presentations at conferences, helping raise the profile of the laboratory’s work and findings. The post holder is required to hold a PhD and to have significant experience – up to five year’s post-doctoral experience – working within cancer biology, stem cell biology or immunology. They should be competent in flow cytometry, basic molecular biology and cell biology techniques, tissue culture, and cancer biology animal models. Experience with biocomputational analyses, neurobiology, proteomics, patient-derived xenografts, or stem cell biology technical skills is desirable. The post holder will provide training in lab techniques to students within the group and help with the overall management of the lab. The post holder is a key member of the laboratory and is critical to establishing a positive research culture. The post is full time (35 hours per week), based at Guy’s campus, for a period of 3 years.  Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information. About You To be successful in this role, we are looking for candidates to have the following skills and experience:  Essential criteria PhD in Neuroscience, Immunology, Molecular Biology, or Cancer Biology Expertise in Flow Cytometry. Expertise in molecular biology Experience of working independently, using own initiative to get complete work on time  Experience in supervising the research of staff and/or students – such as research and/or undergraduate/Masters project students  Expertise in data analysis  Experience writing up research work for publication  Desirable criteria Experience in CAR T research   Proficiency in project management tools and software Experience with biocomputational analyses, neurobiology, proteomics, patient-derived xenografts, or stem cell biology technical skills Expertise in Flow cytometric analyses Experience of working with animal models Experience in writing up own research proposals and grants Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process. Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.  Further Information At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university. The Equality Act of 2010 protects the rights of our students and staff and provides