Fixed-term

We are looking for a Research Technician to support our research studies exploring how a ubiquitin ligase contributes to DNA replication stress repair. The position is funded by an Academy of Medical Sciences grant awarded to Dr Panagiotis Kotsantis and is available for 24 months (full-time at 1.0 FTE). This role involves supporting studies in DNA replication stress response signalling, including: Generate and characterise engineered cell lines with inducible gene expression/depletion, or genetic modifications. Investigate DNA replication stress response using molecular and cell biology approaches, including immunofluorescence microscopy, immunoblotting and DNA fibres. Examine protein localisation at sites of DNA replication and DNA damage using advanced imaging and proteomic techniques. Characterise protein–protein and protein-DNA interactions through biochemical assays, (immunoprecipitation, PLA). Identify and characterise substrates of a target protein using mass spectrometry-based proteomics. Role responsibilities  You will be responsible for: Preparing and conducting experiments including engineered cell line generation, DNA damage response analysis, protein interaction and localisation studies, and proteomic identification of molecular interaction networks. Data acquisition/management, and contributing to analysis and reporting. Supporting day-to-day lab operations, including equipment maintenance, ordering supplies, record keeping, and assisting with regulatory documentation. Providing technical training to students and other lab members. About you We are keen to hear from candidates who have: Bachelor’s degree in biomedicine, biomedical sciences, biochemistry or a related discipline. Experience supporting biomedical related studies, including mammalian cell culture, immunoblotting, immunofluorescence, DNA cloning, molecular biology techniques and data analysis (GraphPad-Prism, ImageJ). Strong organisational and administrative skills, including inventory management, maintaining accurate records, and report writing. A proactive approach to problem-solving and technical troubleshooting, with the confidence to take initiative and work independently. Excellent written and verbal communication skills, and a collaborative, team-oriented approach. Experience with the DNA fibre assay is desirable but not essential. Training will be provided. About us You will join the Genome Stability and DNA Repair Lab, led by Dr. Panagiotis Kotsantis in the Division of Biomedical and Life Sciences (BLS). This role offers an excellent opportunity to gain hands-on experience across diverse research methods and environments. BLS is part of the Faculty of Health and Medicine and is a vibrant and interdisciplinary research environment focused on human health and disease. It offers state-of-the-art facilities and a collaborative, inclusive culture that supports both independent and team-based research, while promoting work-life balance and individual support. Find out more here: https://www.lancaster.ac.uk/biomedical-and-life-sciences/  The Faculty has held a Silver Athena SWAN award since 2014 recognising its commitment to advancing gender equality in higher education and research. Eligibility: This position is not eligible for VISA sponsorship. For informal enquiries please contact Dr Panagiotis Kotsantis (p.kotsantis@lancaster.ac.uk).   Apply Now

Description of the workplaceThe Experimental Oncology research group at the Division of Translational Cancer Research, Lund University, led by Professor Kristian Pietras, is driven by the conviction that a tumour is a communicating organ consisting of several cell types that jointly develop into the deadly disease cancer. Tumors are heterogeneous and contain malignant cells with different proliferative and metastatic potential. While it is a well-established fact that the tumor microenvironment strongly contributes to a tumor’s growth and development, we do not know much about heterogeneity within cell types in the tumor stroma. Our strategy combines high-resolution studies of basic biological concepts with advanced mouse models of cancer and exclusive clinical patient data to investigate the role of the microenvironment in cancer initiation, progression and resistance to treatment. What we offerLund University is a public authority, which means that you will have special benefits, generous annual leave and an advantageous occupational pension. We also have a flexitime agreement that creates good conditions for work/life balance.Read more on the University’s website about being a Lund University employee,Work at Lund University. Work duties and area of responsibilityThe transforming growth factor (TGF)-ß superfamily consists of more than 30 members that regulate cell fate, proliferation, growth arrest and apoptosis in various cell types. Our studies suggest that direct targeting of ALK1 is the most efficient means of exploiting TGF-ß signaling in stromal cells therapeutically. While ALK1 has historically been viewed as an endothelial cell-restricted receptor, our recent studies have identified its expression also in immuno-suppressive macrophages. Inhibition of ALK1 improves the efficacy of immunotherapy as a result of profound alterations in the immune cell landscape. Here, we will mechanistically explore the role for ALK1 at the crossroads of vascular biology and tumor immunity. QualificationsThe requirements for the position are: M.Sc. in a relevant field, or equivalent Completed higher education courses in Oncology Experience from research in Oncology with resulting publications Experience from research with experimental animal models Experience from research employing mulitiplex immunohistochemistry  Additional qualifications for the position are: Completed MD education Experience from various educational research projects EligibilityStudents with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad. Assessment criterionThe employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance. Further informationFixed-term employment for four years in accordance with Chapter 5, Section 7 of the Higher Education Ordinance (HF).The position is a doctoral studentship (PhD position), full-time (100%),with a start date of 1 September 2026 or according to agreement. How to ApplyApplications must be submitted through the University’s recruitment system. The application should include: A CV detailing qualifications and experience relevant to the position. A cover letter explaining the applicant’s suitability and motivation for the position. Degree certificates. Contact details for two referees. Apply Now

Description of the workplaceThe Rundberg Nilsson lab (https://alexandrarundbergn.wixsite.com/home) is looking for a highly motivated and ambitious individual with a Master’s degree in biomedicine, molecular biology, biotechnology, or another relevant field. You should have a strong interest in hematopoiesis, cancer biology, or cellular and molecular disease mechanisms, and a desire to contribute to a growing research environment with high scientific ambitions. The position is based in the Rundberg Nilsson group at the Division of Molecular Medicine and Gene Therapy, Lund University. The group’s research aims to understand the cellular and molecular mechanisms that regulate hematopoietic stem cells and how disruptions in these processes may contribute to leukemic transformation. The work combines experimental stem cell biology with molecular, genomic, and data-driven approaches, with a focus on stress responses, stem cell function, and leukemia development. As a project assistant, you will become an important part of a growing research group, where your role will contribute directly to establishing experimental workflows, advancing ongoing projects, and creating conditions for continued scientific development. The workplace is characterized by close collaboration, scientific curiosity, attention to detail, and a commitment to creating a sustainable and inclusive research environment. What we offerLund University is a public authority, which means you will receive specific benefits, generous annual leave, and an advantageous occupational pension scheme.Read more on the university’s website about working with us: Work at Lund University. Work duties and areas of responsibilityYou will work on experimental research projects in hematopoietic stem cell biology and leukemia. Tasks may vary depending on project needs but will mainly include: Planning, conducting, documenting, and analyzing research experiments Working with cell and molecular biology techniques, such as cell culture, PCR/qPCR, Western blotting, and flow cytometry Working with mouse models, including handling biological material, sampling, and organ isolation in accordance with established permits and regulations Processing and compiling research data and presenting results at lab and project meetings Participate and present in journal clubs, seminars, and other scientific activities Literature searches and review of relevant scientific literature Contributing to order, safety, and sustainable laboratory routines Collaboration with colleagues and external partners when required The work requires careful documentation, the ability to work independently under supervision, strong collaboration skills, and a willingness to contribute scientific ideas as well as practical solutions. QualificationsRequirements for the position: Master’s degree in biomedicine, molecular biology, biotechnology, or a related field High proficiency in both oral and written English Documented experience in practical laboratory work within cell biology, molecular biology, hematology, cancer biology, or a related field (at least 60 ECTS credits or 40 full-time weeks) Experience in planning, conducting, and documenting experimental work in a careful and structured manner Practical experience in flow cytometry, cell culture, PCR/qPCR, and Western blotting Certification/training for laboratory animal work, e.g. LAS certification or equivalent One or more of the following is considered of special merit: Experience working with murine or human hematopoietic cells, bone marrow, blood, or other relevant tissues Experience with flow-assisted cell sorting (FACS) Experience in bioinformatics, basic programming, or analysis of large biological datasets Experience with genetic modification methods (such as CRISPR, lentiviral systems, etc.) Experience with mass spectrometry or other omics-based methods Previous publications, thesis work, or other research merits in a relevant field Interest in pursuing a long academic research career  Further informationThe position is a fixed-term full-time employment (SÄVA) for 6 months,starting from 1 September 2026 or according to agreement.Interviews will take place online and/or at our premises at BMC, Lund University. AI tools may not be used as support during interviews. How to applyThe position is applied for via Lund University’s recruitment system. The application must include: A cover letter describing your motivation and how the position matches your experience and future goals CV, including a list of any publications Degree certificate Documentation of certification/training in laboratory animal work Names and contact details of at least two referees Any other documents you wish to submit Selection will be based on an overall assessment of education, relevant experience, scientific maturity, personal suitability, and the ability to contribute to the research group’s projects and working environment. Apply Now

About the research group We are seeking a highly motivated postdoctoral researcher to join a newly established research group at Faculty of Medicine and MultiPark at Lund University. Our research aims to uncover how microglia dynamically modulate neural circuits to shape memory formation and extinction across health, psychiatric disorders (e.g., anxiety and fear disorders), and neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. The successful candidate will work at the interface of circuit neuroscience and microglial biology, using cutting-edge methodologies including: two-photon microscopy, miniatured microscope, optogenetics, behavioral phenotyping and transcriptomics. Work duties Lead independent research projects within the lab’s research program Perform in vivo calcium imaging and behavioral experiments Analyze neuronal and microglial activity datasets (e.g., calcium imaging) Conduct immunohistochemistry and morphological analysis of microglia and neurons Apply for postdoc fellowship with help from the lab whenever possible. Requirements Essential requirements PhD in neuroscience Hands-on experience with in vivo calcium imaging (either neurons or glia) Experience with microglia biology or neuroimmune interactions Behavioral experiments Solid data analysis skills (e.g., MATLAB or Python for calcium imaging data) FELASA B certification to conduct mouse experiments (or equivalent) Meritorious qualifications Optogenetics or chemogenetics Transcriptomic data analysis Experience with neurodegenerative disease models (e.g., AD/PD) Ability to develop independent research directions Preference will be given to applicants who have obtained their PhD degree no more than three years prior to the application deadline. We offer We offer a supportive environment for developing an independent research profile, mentorship in grant writing and career development, access to state-of-the-art neuroscience and imaging infrastructure. This is a full-time, fixed-term employment of two years initially with possibility of extension. The start date of the position is flexible, however better in fall of 2026. About the position The position is limited to two years with a preliminary start date of 2026-11-01 or by agreement.It is a full-time position. A postdoctoral position is limited to two years with the possibility to extend to three years according to collective agreement for postdocs (The Swedish Agency for Government Employers). A postdoctoral position is intended as an initial step in a scientific career and as an opportunity to develop key competencies as a researcher. Applying for the positionThe application is done via the Lund University recruitment system. The application must contain a personal letter motivating your interest in the position and how it fits your skills and merits. The application must also include your degree certificate, your complete CV and any additional relevant documents that you wish to invoke (grades, contact information for professional references, letters of recommendation etc). Apply Now