Fixed-term

Available on a fixed-term basis for a maximum of 13 months (1 July 2026 – 31 July 2027) (to complete specific time limited work) This role will be based on the university campus. We are open to discussing flexible working arrangements. Are you an ambitious researcher looking for your next challenge? Do you have an established background in protein structure/function analysis by integration of biochemical, biophysical and structural methods? Do you want to further your career in one of the UKs leading research intensive Universities? Antibiotic resistance is projected to cause 10 million deaths per year by 2050, with gram-negative (diderm) pathogens comprising 9 of the 12 bacteria that pose the greatest threat to human health. The outer membrane (OM) of these pathogens acts as a first line of defence against an antibiotic assault and, therefore, finding ways to perturb OM assembly may deliver new routes to kill gram-negative bacteria, or sensitise them to existing antibiotics. We have been studying the mechanism by which outer membrane proteins (OMPs) reach the OM, how chaperones facilitate OMP delivery, and how the β-barrel assembly machinery (BAM) folds/inserts its clients into the OM (e.g. Schiffrin et al, Commun Biol, 2022; Csoma et al, 2025; Fenn et al, 2024; Calabrese et al, Nat Commun, 2020).  In this project we aim to gain new information about a key player in OMP assembly, the periplasmic chaperone SurA. We have previously identified two hotspot regions on SurA that are critical for OMP recognition and now seek to address the following important questions: What are the sequence determinants for OMP recognition and how is communication between binding sites achieved? [using NMR, ITC, native MS, peptide arrays] How does SurA modulate the conformational ensemble of its OMP clients and remodel them to ensure they remain folding-competent? [using smFRET, HX-MS, NMR and other methods] How do mutations in key hotspots alter the range of OMPs found in the OM [using proteomics] and are different hotspots on SurA responsible for binding and delivering different OMPs to BAM [using crosslinking-MS]? Given that deletion of SurA results in OM defects, reduced pathogenicity, and loss of OM integrity, SurA could be a good target for the development of new antimicrobials.  You will be responsible for the acquisition, analysis and integration of data obtained from a range of experimental (including smFRET, proteomics, NMR) and computational (e.g., AlphaFold) techniques, enabling the characterisation of complex and challenging systems involved in OMP chaperoning by SurA and delivery to BAM. You will be based in the laboratories of Dr Antonio Calabrese, Professor Sheena Radford and Dr Anastasia Zhurvaleva, and work closely with collaborators at Leeds. You should have a PhD (or be close to completion) in Chemistry, Biochemistry, Biophysics or a related discipline. You will have an interest in analytical techniques, and whilst significant experience in structural biology and/or biophysics is essential, training in any areas that you lack experience will be provided.   To explore the post further or for any queries you may have, please contact:  Dr Antonio Calabrese, Associate Professor Email: a.calabrese@leeds.ac.uk  Prof Sheena Radford, Astbury Professor of Biophysics Email: s.e.radford@leeds.ac.uk Dr Anastasia Zhurvaleva, Lecturer in Biological NMR Spectroscopy Email: a.zhuravleva@leeds.ac.uk  Email details to a friend Apply Now

This role will be based on the university campus. We are open to discussing flexible working arrangements. Are you an ambitious researcher looking for your next challenge? Do you have an established background in cryoEM/ET and want to join an interdisciplinary, international team to make the next breakthrough in Alzheimer’s disease research? Do you want to further your career in one of the UKs leading research intensive Universities? We are looking for a talented postdoctoral research fellow to join our team investigating protein structures situated within human brain by fluorescence-guided cryoET. This 8-year Wellcome Discovery Award, ‘Seeing inside the human brain’ will involve 3x PDRAs, a research coordinator, two research technicians and a PhD student working between Leeds, London and Amsterdam to decipher pathological mechanisms of Alzheimer’s disease at source. This work will build on our recent breakthrough of determining structures within tissues cryoET (Gilbert et al., Nature, 2024). You will work with an integrated team of structural biologists, pathologists and neurologists using correlative imaging and cryoET to investigate the structural basis of amyloid assembly, spread and toxicity within Alzheimer’s disease.  You will be based in the laboratories of Rene Frank. For this position you should have (or be close to completing) a PhD in Structural biology (cryoEM/ET) to elucidate protein assembly mechanisms. The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was re-awarded a Silver award in 2025.  We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.  Salary Requirements of the Skilled Worker Visa Route  Please note that this post may be suitable for sponsorship under the Skilled Worker visa route but first-time applicants might need to qualify for salary concessions. For more information please visit: www.gov.uk/skilled-worker-visa. For research and academic posts, we will consider eligibility under the Global Talent visa. For more information please visit: https://www.gov.uk/global-talent What we offer in return  26 days holiday plus approx.16 Bank Holidays/days that the University is closed by custom (including Christmas) – That’s 42 days a year!  Generous pension scheme plus life assurance– the University contributes 14.5% of salary  Health and Wellbeing: Discounted staff membership options at The Edge, our state-of-the-art Campus gym, with a pool, sauna, climbing wall, cycle circuit, and sports halls.  Personal Development: Access to courses run by our Organisational Development & Professional Learning team.  Access to on-site childcare, shopping discounts and travel schemes are also available. And much more!    To explore the post further or for any queries you may have, please contact:  René Frank, Associate Professor & UKRI Future Leader Fellow Email: r.frank@leeds.ac.uk  Apply Now

We are seeking a motivated and collaborative individual to join our team as a Research Associate. This role offers an exciting opportunity to work closely with a research team working on a Medical Research Council (MRC) funded project which aims to characterize non-coding regions of the genome that confer risk to osteoarthritis (OA) using functional genomics, within a dynamic and inclusive environment. You will be responsible for: To carry out an array of laboratory based functional genomics experiments in human cell lines and primary cells, including Hi-C, CUT&RUN, ATAC-Seq, RNA-Seq, CRISPR/Cas9, single cell RNA-seq. To collect and process human samples. Design experiments and analyse the data using appropriate bioinformatic techniques. Be competent in a range of laboratory epigenetic/molecular biology techniques. About You We encourage applications from individuals with a wide range of backgrounds and experiences. You should demonstrate: Essential Criteria: Hold, or be about to obtain, a PhD in functional genomics. Strong background and theoretical knowledge of functional genomics, epigenetics and regulation of gene expression. Excellent knowledge of the genetics of osteoarthritis. Experience in patient recruitment, and blood and joint sample processing (cartilage, synovium). Desirable Criteria: Experience in single cell RNA-seq. Experience of analysing genomic data including RNA-Seq. Knowledge of public resources of human epigenomic data, e.g. Roadmap, Blueprint, Encode. Our benefits include: • Generous employer contribution pension• 29 days annual leave plus bank holidays, along with Christmas closure• Ride to work and EV car scheme available For more information, please see University of Manchester Benefits. You can also find information on our Flexible and Hybrid working here. We are an open place of enquiry and challenge. We embrace and celebrate difference, diversity and debate, and we pride ourselves on being a place of education, learning and community where we are able, within the law, to question and test received wisdom, express new ideas and explore controversial or unpopular topics and opinions. Find out more from our Freedom of Speech Policy. Enquiries about the role, shortlisting and interviews Name: Gisela Orozco Email: gisela.orozco@manchester.ac.uk General enquiries and administrative support recruitmentservices.people@manchester.ac.uk Technical and job portal support https://jobseekersupport.jobtrain.co.uk/support/home Applications close at midnight on the closing date. Further particulars (with person specification) linked below. Supporting Documents save_altBMH-031725 – Research Associate – FPs (PDF, KB) Apply Now

The Opportunity:  Project title: Investigating global RNA homeostasis with cell size   We are seeking highly motivated candidates to join the Swaffer lab as a research assistant to work on how cell size impacts RNA biology. We’re a multi-disciplinary group that combines approaches across cell, molecular, systems & quantitative biology to study how core cellular processes are altered by cell size.   Cell size is a fundamental but poorly understood cellular property, and cells must adapt their global RNA metabolism as they grow larger to keep their internal biochemistry stable. This project will involve using yeast genetics to understand this phenomenon and build on our recent progress (Swaffer et al., Cell 2023). This project will involve using standard molecular biology, quantitative imaging and sequencing-based assays to investigate how different aspects of RNA biology are altered as cell size increases, including investigating non-coding RNAs, ribosome assembly and RNA turnover.  Your skills and attributes for success:   Strong motivation to contribute to a novel area of cell biology research: i.e. cell size.  Strong organisational, communication and critical thinking skills to drive success working both independently and as part of a collaborative team.   Understanding of key techniques in molecular biology and yeast genetics.  Understanding of key concepts and techniques in RNA biology.  View the full job description. How to apply  Please include the following documents in your application:   CV  Motivation statement detailing your research experience, interests and motivations for joining the lab  Please contact the hiring manager (Dr. Matthew Swaffer at matthew.swaffer@ed.ac.uk) for any queries. Informal enquiries are encouraged.  As a valued member of our team, you can expect:   To be part of an exciting, creative, and rigorous research team. The Swaffer lab is based within the Institute for Cell Biology which provides an inclusive, supportive, and highly collaborative scientific environment supported by state-of-the-art technology facilities via the Discovery Research Platform for Hidden Cell Biology. You will benefit from expert training in cutting-edge approaches in cell, molecular and systems biology as well as wider career mentoring and support to nurture your talents and drive success. You will benefit from a competitive reward package and a wide range of staff benefits, including generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and more. Click to access our staff benefits page (opens new browser tab) for further information and use our reward calculator to find out the total value of pay and benefits provided.  Championing equality, diversity, and inclusion  The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter, and we are also a Stonewall Proud Employer, actively promoting LGBTQ+ equality.   Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages (opens new browser tab)   On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.   Key dates to note  The closing date for application is 16 July 2026.  Unless stated otherwise the closing time for applications is 11:59pm UK time. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone. Apply Now

Job TitleProfessor (Animal Nutrition, Veterinary Pharmacology & Toxicology, Livestock Products Technology, Veterinary & Animal Husbandry Extension Education, Veterinary Surgery & Radiology, Veterinary Gynaecology & Obstetrics, Veterinary Medicine, Veterinary Clinical Complex) Number of Posts Professor (Animal Nutrition): One Professor (Veterinary Pharmacology & Toxicology): One Professor (Livestock Products Technology): One Professor (Veterinary & Animal Husbandry Extension Education): One Professor (Veterinary Surgery & Radiology): One Professor (Veterinary Gynaecology & Obstetrics): One Professor (Veterinary Medicine): One Professor (Veterinary Clinical Complex): One Salary For candidates having age upto 65 years: Remuneration at the last pay drawn (basic pay + NPA as applicable) minus pension (basic) subject to a minimum of Rs. 1.0 lakh per month. For candidates with the age between 65 to 70 years: Negotiable fixed salary maximum upto Rs. 1.0 lakh per month. Note: The retired persons so appointed will not be eligible for any benefit under CPF/GPF/NPS and will not be eligible for any other allowance(s) during the period of contract. LocationCollege of Veterinary Science, Rampura Phul, Bathinda Eligibility Teachers/scientists retired from any University/Institute. Contract duration: Initial period of one year. RequirementsGeneral Requirements for all posts: Must have passed Matriculation examination of Punjabi Language from Punjab School Education Board or any other recognized Board (as first or second or as additional language) or any other equivalent examination in Punjabi language on or before the last date of submission of application. B.V.Sc. & A.H./ B.V.Sc. with at least second division (from a recognized institution for the Veterinary & Animal Husbandry Extension Education post). An eminent scholar actively engaged in teaching/research/extension with published work with a minimum of 10 publications as books and/or research/policy papers in indexed/ISBN/ISSN numbered journals and as ISBN/ISSN numbered books. Ten years’ experience in teaching/research/extension education in the relevant discipline, out of which at least two years should be as Associate Professor or equivalent in the pay scale of Rs. 37400-67000 + AGP/GP Rs. 9000/- (unrevised) and remaining as Assistant Professor or equivalent. (The period spent in obtaining Ph.D. degree will not be counted as research experience). Post-Specific Qualifications: Professor (Animal Nutrition): Ph.D. degree in Animal Nutrition. Master’s degree in Animal Nutrition with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary Pharmacology & Toxicology): Ph.D. degree in Veterinary Pharmacology & Toxicology/Veterinary Pharmacology. Master’s degree in Veterinary Pharmacology and Toxicology/Veterinary Pharmacology with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Livestock Products Technology): Ph.D. degree in Livestock Products Technology/Meat Science/Animal Products Technology. Master’s degree in Livestock Products Technology/Meat Science/Animal Products Technology with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary & Animal Husbandry Extension Education): Ph.D. degree in Veterinary & Animal Husbandry Extension Education/Veterinary & Animal Husbandry Extension/Veterinary Extension. Master’s degree in Veterinary & Animal Husbandry Extension Education/Veterinary & Animal Husbandry Extension/Veterinary Extension with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary Surgery and Radiology): Ph.D. degree in Veterinary Surgery & Radiology. Master’s degree in the relevant discipline with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary Gynaecology and Obstetrics): Ph.D. degree in Veterinary Gynaecology & Obstetrics/Animal Reproduction Gynaecology & Obstetrics. Master’s degree in the relevant discipline with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary Medicine): Ph.D. degree in Veterinary Medicine. Master’s degree in the relevant discipline with minimum OCPA of 6.50 out of 10.00 or 65% marks. Professor (Veterinary Clinical Complex): Ph.D. degree in Veterinary Medicine/Veterinary Surgery & Radiology/Veterinary Gynaecology & Obstetrics. Master’s degree in the relevant discipline with minimum OCPA of 6.50 out of 10.00 or 65% marks. Job ResponsibilitiesProfessor (Animal Nutrition): To undertake effective management of Animal Nutrition Farm Complex including agricultural farms. To undertake various programmes on Nutritional interventional for farm animals. To develop nutritional technologies for farm animal species improvement under field conditions. To undertake academic research and extension education work in Animal Nutrition. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary Pharmacology & Toxicology): Assigned teaching duties. Development of modern teaching facilities. Research/extension/education work. To take initiative in bringing research projects for strengthening the research and teaching programme. Any other duty assigned from time to time. Professor (Livestock Products Technology): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary & Animal Husbandry Extension Education): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary Surgery and Radiology): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary Gynaecology and Obstetrics): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary Medicine): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Professor (Veterinary Clinical Complex): Teaching/Research/Extension duties. To take initiative/steps in bringing research projects for strengthening the research, teaching and extension education programme. Any other duty assigned from time to time. Age Limit Candidates having age upto 65 years (eligible for remuneration based on last pay drawn minus pension). Candidates with the age between 65 to 70 years (eligible for negotiable fixed salary). Last Date03.07.2026 How to Apply Applications must be submitted in the prescribed format. Candidates should enclose attested copies of all certificates of qualifications, detail marks, experience, and last pay certificate along with the application form. In case of an emergency, if the candidate is unable to submit the hard copy of the application upto the last date of receipt of applications, they may send the application (in PDF) on email: registrar@gadvasu.in upto 03.07.2026, followed by the hard copy in due