Fixed-term

At St. Anna Children’s Cancer Research Institute (St. Anna CCRI), translational medicine is driven by a single purpose: turning scientific insight into tangible clinical impact for pediatric cancer patients. To further strengthen our portfolio in translational discovery and therapeutic development, we are seeking an outstanding Principal Investigator in Translational Medicine for Pediatric Cancer. This position is open to candidates at different career stages – from emerging group leaders to experienced Principal Investigators. In this role, you will establish and lead an innovative research program dedicated to the discovery, validation, and development of novel therapeutic strategies, with a strong focus on one or more key modalities, e.g. small molecules, drug repurposing, immunotherapies, or biologics, embedded in a broader translational ecosystem covering complementary approaches, within a uniquely integrated bench‑to‑bedside environment closely linked to precision oncology and early‑phase clinical studies. Key responsibilities Establish and lead a translational research program in pediatric cancer therapy: Develop innovative therapeutic strategies with a clear primary focus in a key therapeutic modality, e.g. small molecules, drug repurposing, immunotherapies, or biological therapeutics, while maintaining a strong openness for collaborative integration across complementary approaches.  Drive discovery and therapeutic development: Lead target identification, mechanism‑of‑action studies, and compound screening efforts embedded in a translational pipeline. Translate discovery into clinical concepts: Integrate research findings with precision oncology initiatives to enable biomarker‑informed and clinically relevant therapeutic strategies. Strengthen early‑phase translational interfaces: Collaborate closely with the St. Anna CCRI Clinical Trials Unit, Statistics, and St. Anna Children’s Hospital to support robust preclinical‑to‑clinical translation. Build and lead a multidisciplinary research team: Recruit, mentor, and guide scientists while ensuring scientific rigor, reproducibility, and regulatory alignment. Ensure visibility, collaboration and sustainability: Secure competitive third‑party funding, publish high‑impact research, and represent St. Anna CCRI in international translational medicine networks and consortia. Required Qualifications PhD or MD/PhD in biomedical sciences with demonstrated deep expertise in at least one therapeutic development modality (e.g. small molecules, biologics, immunotherapy), with the ability to position this expertise within broader translational strategies.  Postdoctoral research experience, with a strong publication track record. Demonstrated experience in therapeutic development, including target identification, high-throughput or focused compound screening, and mechanism‑of‑action studies.  Familiarity with 2D/3D model systems and relevant in vivo models (e.g., zebrafish, PDX or other preclinical tumor models).  Proven success in securing competitive external funding and leading independent research.  Experience working in interdisciplinary and collaborative environments, ideally with clinical or translational partners.  Strong mentoring and leadership skills in supervising PhD Students, Postdocs, or scientific staff.  Excellent communication skills, with the ability to convey complex scientific findings clearly and to work effectively within collaborative, interdisciplinary research environments. Excellent communication skills and fluency in English. Our offer Internal funding & strong institutional commitment: Competitive core budget and comprehensive start-up resources including dedicated laboratory space, access to core equipment, and support in building and scaling your independent research team. Access to cutting‑edge research infrastructure: State‑of‑the‑art technology platforms in genomics, imaging, proteomics, high‑throughput screening, and advanced in vivo and ex vivo disease models, embedded in a strong translational ecosystem. Embedded collaborative ecosystem: Close interaction with clinicians, precision oncology initiatives, early‑phase clinical trials, and interdisciplinary research groups across discovery and translational medicine. Professional grant support: Institutional assistance with proposal development and professional grant management. Attractive employment conditions, culture & location: Flexible working arrangements, tailored onboarding support for international researchers, and a diverse, mission‑driven culture dedicated to improving outcomes for children with cancer, based in Vienna, offering outstanding quality of life and a strong biomedical ecosystem. Compensation: The minimum annual gross salary for this position is € 78.000.- (all in), with the possibility of higher compensation depending on qualifications and experience. Contract terms: Appointment terms will be aligned with the candidate’s career stage. Starting Principal Investigators will be offered a 5‑year appointment with the possibility of a further 4‑year extension following positive evaluation. Senior Principal Investigators may be appointed on a rolling tenure basis, with regular evaluations every 5 years, reflecting the institute’s long‑term strategic commitment to scientific leadership. Who we are One of Europe’s leading institutions in the field of pediatric oncology, St. Anna Children’s Cancer Research Institute (St. Anna CCRI) investigates the biological foundations of cancer in children and adolescents. For almost 40 years, our multidisciplinary teams have been committed to developing innovative diagnostic approaches and personalized treatments aimed at further improving young patients’ chances of cure. In close collaboration with the St. Anna Children’s Hospital and both national and international partners, we combine scientific excellence with clinical relevance. We stand for responsible research, transparency, and sustainable knowledge building. As an employer, we offer a state-of-the-art research environment, opportunities for professional development, as well as a workplace culture that embraces diversity and appreciation. Work where it really matters and contribute to science that makes a difference. St. Anna CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, colour, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances. Find more information here: https://ccri.at/. Your application We are looking forward to your application! The application deadline ends on 23.08.2026. Please submit the following documents:      • Curriculum Vitae (including full publication list)      • List of up to five most important publications with a short comment explaining the relevance of the paper and your contribution      • Funding track record      • Names and contact details of at least three references      • Synopsis of your research interests and planned research program including how you and St. Anna CCRI could mutually benefit from each other In case of questions please contact us at faculty-recruiting@ccri.at. Your recruiting process Our recruitment process is designed to ensure a fair, transparent, and rigorous evaluation. It includes the following steps: Initial screening and pre‑selection: All applications are reviewed and assessed based on predefined core criteria relevant to the position. Virtual interviews with the Scientific Directors: Shortlisted candidates are invited to participate in two separate virtual one‑on‑one interviews – one with each Scientific Director of St. Anna CCRI. On‑site hearing (18 – 20 September 2026): The

A 3-year PhD student position (30 h/week) is available from October 2026 in an Austrian Science Fund (FWF)-funded project in the laboratory of DDr. Reinhold G. Erben at the Ludwig Boltzmann Institute of Osteology in Vienna, Austria.  The deadline for receipt of applications is August 10, 2026. Please include CV, scientific experience, and references in your application. What you can achieve with us The project addresses the bone-kidney axis, employing a combination of in vivo studies using different transgenic mouse models with in vitro cell and tissue culture approaches to better understand the regulation of fibroblast growth factor-23 (FGF23) secretion in bone and the pathophysiological sequelae of FGF23 excess in renal disease.  What you bring to the role We are looking for a highly motivated PhD student with medical, veterinary, or biology training. The PhD student will participate in the PhD program of the Medical University Vienna or of the University of Veterinary Medicine Vienna. We can offer an outstanding research environment with state-of-the-art infrastructure and excellent opportunities for international networking. Approaches used include animal studies, spatial transcriptomics and metabolomics, proteomics, ChIP-Seq, µ-CT, immunohistology, histomorphometry, cell culture, and tissue culture. Working language is English.  What you can expect from us The opportunity to make a contribution that improves the lives of people in Austria and around the world and creates a solid basis for political action and decision-making. A Career Center that supports you in your personal and professional development and enables you to engage in lifelong learning and continuous professional development. Work-life balance through individual teleworking agreements, working time models, and professional parental leave management. Counseling services for you and your family on issues of physical and mental health. Team events such as team days, business runs, and Christmas parties that promote personal exchange and strengthen cohesion. A gross monthly salary starting at EUR 3.876 (full-time). Depending on qualifications and experience, a higher salary is possible. Application Please send us your application documents via our online application form, stating your salary expectations. We look forward to receiving your application Contact details Priv. Doz. Dr. Markus Hartmann Application Form

Department of Nutrition, Exercise and Sports invites applicants for a PhD fellowship in Gut Microbiome and Cardiometabolic Health. The project is part of the Microbiome Health Initiative (MHI), which is supported by the Novo Nordisk Foundation. Start date is (expected to be) 01.10.2026 or as soon as possible thereafter. The project MHI is an initiative that aims to show that the human gut microbiome plays a causal role in cardiometabolic health. As part of this, several human intervention studies are to be conducted testing the effects of microbial species or microbial metabolites on outcomes relevant for cardiometabolic health. The envisioned PhD project will investigate whether rectal administration of a microbiota-derived metabolite affects colonic hormone secretion and metabolism in humans. A placebo-controlled cross-over trial in human participants will be conducted at Steno Diabetes Center Copenhagen and combine measurements of gut hormones and human metabolism and state-of-the-art omics technologies on biological samples (i.e. transcriptomics, microbiomics and metabolomics). In addition, the PhD student will contribute to other ongoing related research projects. In your role as PhD student, you will be in charge of writing the study protocol for approval to the Ethical Committee. Following approval, you will be responsible for the recruitment of study participants and for conducting the cross-over intervention study in collaboration with other staff and students. This includes conducting examination visits, handling biological samples, and potentially taking rectal biopsies. Furthermore, you will conduct liquid chromatography mass spectrometry-based metabolomics on biological samples from this and other trials, and analyze transcriptomics and microbiome data obtained from the studies. Finally, you will integrate the clinical intervention-responses with obtained omics data and write scientific publications. The position involves collaborative work with Research leader, MD, Trine Nielsen and her team at Steno Diabetes Center Copenhagen, Denmark. Who are we looking for? We are looking for motivated candidates within the field(s) of medicine (medical doctor), human physiology, human biology, human nutrition, biotechnology or similar field who has a keen interest in studying/learning human gut physiology and omics technologies to work interdisciplinary and bridge human intervention studies with basic science. Our group and research- and what do we offer? You will be part of the Nutrition, Microbiome and Metabolomics Group headed by Associate Professor Henrik Munch Roager at Department of Nutrition, Exercise and Sports, Faculty of Science at University of Copenhagen. We offer a dynamic, sociable, collaborative, and international environment with exciting scientific challenges and opportunities to develop your scientific career. The core of our research is to perform high quality human interventions and cohort studies with a strong emphasis on measuring diet-microbiome-host interactions through metabolomics. The research group is part of the Microbiome Health Initiative, which brings together world-leading microbiome scientists and clinicians to generate knowledge that can lead to new prevention or treatment options for people living with, or at risk of, cardiometabolic diseases. The group is also affiliated to the Copenhagen Gut Microbiome Hub, which brings together the region’s leading scientists, researchers and industry professionals dedicated to leverage the gut microbiome to improve health. The University is situated in Copenhagen, which is consistently rated among the world’s top 10 most livable and sustainable cities. Life for families is made easier via a publicly supported daycare and healthcare system, dual-career opportunities, maternity/parental leave, and six weeks of annual vacation. International candidates may find useful information on living and working in Denmark. Useful information is also available at the university’s International Staff Mobility (ISM) office, which offers a variety of services to international researchers coming to and working at the University of Copenhagen. The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background. Principal supervisor is Associate Professor Henrik Munch Roager (hero@nexs.ku.dk), Department of Nutrition Exercise and Sports, University of Copenhagen. Getting into a position on the regular PhD programme Qualifications needed for the regular programmeTo be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. [relevant educations]. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database. Terms of employment in the regular programmeEmployment as PhD fellow is full time and for maximum 3 years. Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of Science, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant. Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure. Responsibilities and tasks in both PhD programmes Complete and pass the MSc education in accordance with the curriculum of the MSc programme (ONLY when you are attending the integrated MSc and PhD programme) Carry through an independent research project under supervision Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE Participate in active research environments, including a stay at another research institution, preferably abroad Teaching and knowledge dissemination activities Write scientific papers aimed at high-impact journals Write and defend a PhD thesis on the basis of your project We are looking for the following qualifications: A Master’s degree in Medicine, MSc degree in Human Physiology, Human Biology, Human Nutrition, Biotechnology or related fields with excellent results. Applicants expecting to obtain a master´s degree in medicine or MSc degree soon are also encouraged to apply. The candidate will be self-motivated with the ability to work independently as well as competent to collaborate as part of an interdisciplinary team. A creative and curious mindset and a strong drive Excellent communication skills in spoken and written English. Excellent communication skills in Danish (or related Nordic language) is an advantage Prior experience and hands-on in any of the following areas is an advantage: Clinical experience and/or experience with taking biopsy Hands-on experience with human intervention/cohort studies Omics data analysis, statistics and R

The University of Copenhagen is seeking a highly motivated and talented PhD fellow to commence November 15, 2026, or after agreement, in the Sakamoto Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. About CBMR The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an academic research Center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, CBMR aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies. The Center’s uniquely multi- and interdisciplinary approach combines research in genetics, physiology and pharma­cology, to better understand the complex interplay of the many factors that drive cardiometabolic disease. You can learn more in the Executive Summary of CBMR’s Strategy 2024–2028. CBMR was established in 2010 at the Faculty of Health & Medical Sciences and has been located in the Maersk Tower at Panum since 2017. The around 260 employees create an international, highly collaborative research environment across disciplines. Our group and research The overarching aim of the Sakamoto Group is to elucidate molecular mechanisms governing cellular energy sensing, as well as the maintenance of metabolic homeostasis. Our ultimate goal is to identify therapeutic targets and their small-molecules or peptide-based modulators capable of restoring energy balance in cardiometabolic disease. Our research focuses on how post-translational modifications—particularly reversible phosphorylation—and allosteric regulation of signaling proteins and metabolic enzymes contribute to metabolic control. We also investigate how disruptions in these processes drive the development and progression of cardiometabolic diseases. To address these questions, we employ a multidisciplinary approach and collaborate with leading national and international experts. We are equally committed to fostering a supportive and dynamic research environment, with a strong emphasis on the training and professional development of early-career scientists. Project description Maintenance of energy and glucose homeostasis is essential for metabolic health. Our group has previously shown that glucose utilization in skeletal muscle and liver is governed by coordinated regulation through reversible phosphorylation and allosteric control, using novel knock-in mouse models expressing metabolic enzymes carrying phospho-deficient or allosteric modulator-binding-deficient mutations. This project will focus on defining how glucose phosphorylation by hexokinase 2, together with its allosteric negative feedback regulation, controls skeletal muscle glucose flux and utilization in vivo, and how this contributes to whole-body glucose homeostasis under both physiological and pathophysiological conditions. The successful candidate will perform biochemical analyses combined with structure-guided mutagenesis (cell-free and cell-based assays) to identify allosteric modulator-resistant mutants, as well as in vivo preclinical studies in multiple genetic mouse models, including metabolic phenotyping and assessment of glucose homeostasis. Principal supervisor is Professor Kei Sakamoto, email: kei.sakamoto@sund.ku.dk Start: November 15, 2026 Duration: 3 years as PhD fellow. Job descriptionYour key tasks as a PhD student at SUND are: Carrying through an independent research project under supervision. Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points. Participating in active research environments including a stay at another research team. Obtaining experience with teaching or other types of dissemination related to your PhD project Teaching and disseminating your knowledge. Writing a PhD thesis on the grounds of your project Key criteria for the assessment of applicantsApplicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. biochemistry, physiology, pharmacology, molecular biomedicine. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years). Other important criteria are: Hands-on experience in performing cell culture experiments (e.g. transfection/gene editing, drug treatment), biochemical/metabolic analysis (e.g. enzyme assays, metabolomics) and cell signaling (e.g. Western blotting, proteomics) Hands-on experience in conducting in vivo preclinical studies and metabolic phenotyping (FELASA certified or similar) Ability to manage and analyze complex data sets A curious and critical mindset with strong self-motivation to develop new knowledge and treatment for complex cardiometabolic diseases Ability to work independently and work as a team player Excellent English communication skills, both written and oral Place of employment The place of employment is at Novo Nordisk Foundation Center for Basic Metabolic Research, Maersk Tower, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Terms of employmentThe average weekly working hours are 37 hours per week. The position as PhD student is a fixed-term position limited to a period of 3 years. The start date is November 15, 2026, or after agreement. The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant. The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. QuestionsFor specific information about the PhD fellowship, please contact Professor Kei Sakamoto (kei.sakamoto@sund.ku.dk) or Marianne Jensen PhD (marianne.jensen@sund.ku.dk) . For questions regarding the recruitment procedure, please contact SUND HR CBMR at hr-cbmr@adm.ku.dk . International applicants may find these links useful www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/ .  General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/ Application procedureYour application must be submitted electronically by clicking ‘Apply for position’ below. The application must include the following documents in PDF format:  1. Motivated letter of application (max. one page) 2. CV incl. education, experience, language skills and other skills relevant for the position 3. Certified copy of original Master’s diploma and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. 4. Publication list (if possible) Application deadline: August 10, 2026, 23.59pm CET We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. The further processAfter the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment

We are offering 2 or more PhD fellowships in Cardiac Physiology laboratory, 1 commencing on the 1st of November 2026 or soon after, and the others no later than 1 June 2027. Project description We are looking for a dedicated PhD student, who will be working on understanding mechanism of cardiac pathophysiology. The PhD student(s) recruited for this project will work with several of the many translational modalities in the Cardiac Physiology, spanning from long-term porcine and rodent models of cardiac diseases, ex vivo (human) tissue analyses, electrophysiology, biochemistry, histology, and cMRi, to disclose the underlying mechanisms of cardiac disease from molecule to beating hearts. Cardiac Physiology laboratory Our research team is headed by Prof. Dominik Linz and Prof. Thomas Jespersen, as well as a number of junior research group leaders, ensuring both highly specialised knowledge on our fairly broad research focus, as well as delivering competent and present research leadership and supervision to the younger researchers in the team. (https://bmi.ku.dk/english/research/cardiac_physiology_laboratory/) We are a team of ~35 researchers all highly dedicated to moving the boundaries of the known within the cardiac field, with the overall aim of improving understanding and thereby health of the heart. All our research is based on team efforts, where we all are willing to go the extra mile – sometimes evenings and weekends, but always in the best of spirits with colleagues who are continuously inclusive and positive. Principal supervisor will be either Thomas Jespersen or Dominik Linz and always backed up by the junior research group leaders. Information regarding the position can be directed to Thomas Jespersen (thojes@sund.ku.dk), or Dominik Linz (dominik.linz@sund.ku.dk). Start: 1st of November 2026, and no later than 1 June 2027.   Duration: 3 years as a PhD fellow Job descriptionYour key tasks as a PhD fellow at SUND are: Carrying out independent research projects under supervision. Being project-responsible for projects involving translational cardiac research – the exact project will be matched with the competences of the candidate. Completing PhD courses and other equivalent education corresponding to approximately 30 ECTS points. Participating in active research environments, including a stay at another research team/institution. Gaining experience with teaching or other types of dissemination related to your PhD project. Teaching undergraduate students and disseminating your knowledge. Writing a PhD thesis based on your project.  Key criteria for the assessment of applicantsApplicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. medicine, veterinary medicine or molecular/cellular biology. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).Prior experience in working with cardiac electrophysiology and models of cardiac disease, as well as a solid understanding in cardiovascular physiology is an advantage.  Other important criteria are: Professional qualifications relevant to the PhD project, Previous publications, Relevant methodological experience, including data science and omics, Other professional and complementary skills, A curious mind-set with a strong interest in cardiac biology, Both good in driving projects forwards as well as collaborating with peers and external partners, High proficiency in English Place of employment The place of employment is at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Terms of employmentThe average weekly working hours are 37 hours per week. The position is a fixed-term position limited to a period of 3 years. The start date is November 1st 2026, and others no later than 1 June 2027. The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.   The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 31,600 DKK/Roughly 4,220 EUR (April 2026 level) plus fully paid pension 18,07%. QuestionsFor specific information about the PhD fellowship, please contact the principal supervisor. General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/ Application procedureYour application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:  1. Motivated letter of application (max. one page) 2. CV incl. education, experience, language skills and other skills relevant for the position 3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database/?set_language=en. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science 4. Publication list (if possible) Application deadline: 30 August 2026, 23:59 pm CET We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. The further processAfter the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement. Once the assessment work has been completed each applicant has