Fixed-term

Clinical Research Fellow – Department of Inflammation and Ageing

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Position Details Department of Inflammation and Ageing, School of Infection, Inflammation and Immunology, College of Medicine and Health Location: University of Birmingham, Edgbaston, Birmingham UK Full time starting salary is normally in the range £45,943 – £77,196 Clinical Full Time, Fixed Term contract up to March 2029 Closing date: 12th March 2026 Background The Medical Research Council (MRC) has recently funded a Four-year, £1.5M cohort study, that is studying the impact of e-cigarettes on immune and epithelial cells within the lungs of smokers trying to quit using e-cigarettes. Smoking is the leading cause of preventable death worldwide, and a risk factor for many diseases. With an ageing population, the profound economic and health burden of smoking-related disease continues to increase. E-cigarettes are an effective, NICE recommended smoking cessation tool yet the long-term effects of vaping remain uncertain. Our short-term exposure studies have shown the deleterious effects of e-cigarette exposure on innate immune cell function (neutrophils, alveolar macrophages), suggesting potential harm from chronic exposure. This project aims to address this knowledge gap by recruiting a cohort of healthy smokers aiming to quit smoking using e-cigarettes, to provide critical data needed to determine safety and to inform personal choice, public debate, and policy. This longitudinal cohort study will evaluate accumulation of toxins in the airways, changes in epithelial and innate immune cell functions during smoking cessation, by combining a multi-omic approach with whole-cell effector functions and characterise changes in the respiratory microbiome. This vacancy is for a clinical research fellow (CRF) working as part of the Acute Care research theme in the department of Inflammation and Ageing at the University of Birmingham. The post will deliver a mixed job role working within the University of Birmingham as an MRC funded fellow (60%) and supporting the NIHR Clinical Research Facility (40%) aiding in the delivery of early phase and first-in-man clinical trials. Role Summary The post-holder will contribute to the creation of knowledge by undertaking a specified range of activities within an established research project, specifically an MRC funded Project grant EVALUATE. The CRF will lead on delivery of this cohort study, driving patient recruitment in collaboration with nursing team at the NIHR Clinical Research Facility, supervising and undertaking sample collection including bronchoscopic sampling of the lower airways and ensuring participant eCRFs are and clinical databases are updated throughout the study. The post holder will benefit from the infrastructure and expertise in the Acute care team, as well as the track record of delivering patient cohort studies and clinical trials. This job share role will be integrated with a 40% job role with the NIHR Clinical Research Facility to support delivery of early phase clinical trials which require clinical support. This post is funded for 36 months. The post-holder will be expected to register for a higher degree and will be supported to apply for further development and funding. Main Duties To coordinate recruitment of patients, including patient identification and consent and performance of study-related procedures where relevant To assist with study set-up and obtaining necessary local and national approvals (ethics, MHRA) and contribute to site file and data management under guidance of the trials coordinators and lead investigators. To carry out a literature review of the topic area. To gain sufficient research data and experience that will enable completion of a higher degree (PhD or MD). To comply with the terms and conditions set out in the University of Birmingham’s graduate Programme of study. To contribute to the enhancement of scientific understanding of pulmonary inflammatory disease mechanisms in accordance with the aims of the project grant. To undertake prescribed research tasks and collection of research data To prioritise tasks within the agreed work schedule to ensure that projects are delivered in a timely fashion according to the timelines in the project grant. To suggest and contribute to the development of research techniques and methods in collaboration with colleagues. To contribute to writing bids for research grants. To disseminate research findings using appropriate and effective media such as publication, research seminars, etc. To provide guidance to other staff and students. To contribute to the production of research reports and high impact publications. To plan and develop research contributions to subject area using methodologies, critical evaluations, interpretations, analyses and other appropriate techniques. To participate in departmental and project-specific public engagement activities and initiatives Required Knowledge, Skills, Qualifications, Experience Essential Primary Medical Qualification. Full GMC registration Satisfactory completion of Foundation Training (or equivalent). Desirable MRCP or equivalent. Relevant higher degree. ALS. Up-to-date training in Good Clinical Practice. Clinical Skills and Knowledge Essential At least 1 year of previous experience working in the NHS. To be clear, fluent and articulate in communication in English. Able to assess patients face to face and via telephone. Good history & examination skills. Able to formulate a working diagnosis. Able to order appropriate investigations. Image interpretation relevant to practice. Ability to manage common medical emergencies. Knows when to appropriately seek assistance from a senior colleague. Desirable Experience and interest in the specialty. Neat, legible writing of notes and charts. Ability to perform basic general procedures, including lumbar puncture (although training can be provided) Experience in clinical research at F1/F2/ST1 level. Maintaining Clinical Competence Essential Maintaining Clinical Competence Teaching Essential Able to contribute to teaching of others in the clinical and research setting Desirable Contribution to departmental training sessions. Some knowledge of learning theories. Experience of teaching undergraduate medical students & Foundation Doctors. Clinical Governance, Audit and Research Essential Experience of audit projects. Understanding of research principles. Desirable Presentation of completed audit projects at local or national meetings. Organised or contributed to an audit project that has resulted in change. Evidence in participation in research projects. Publication of research in peer reviewed journals and presentation at local and national meetings. OH and DBS required The University is committed to safeguarding and we promote safe recruitment practice, therefore all associated pre-employment checks will be undertaken before any appointment is confirmed. Due to the nature of the work undertaken in this role all successful applicants will be subject to a satisfactory Occupational Health and DBS clearance prior to appointment. Further particulars can be found here Informal enquiries to Abbie Riley, email: a.riley.1@bham.ac.uk Use of AI in applications: We want to understand your genuine interest in the role and for the written elements of your application to accurately reflect your own communication style. Applications that rely too heavily on AI tools can appear generic and lack the detail we need to assess your skills and experience. Such applications will unlikely be progressed to interview. Apply Now

Position for Senior Research Technician

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Position Details Department of Cancer and Genomic Sciences, School of Medical Sciences, College of Medicine and Health Location: University of Birmingham, Edgbaston, Birmingham UK Full time starting salary is normally in the range £29,647 to £31,460, with potential progression once in post to £35,388 Grade: 5 Full Time, Fixed Term contract up to December 2027 Closing date: 12th March 2026 Background This full time position (35 hours/week) within the College of Medicine and Health, School of Medical Sciences, Department of Cancer and Genomic Sciences and will be supporting the research of Professor Andrew Beggs. This post is funded by Neogene Therapeutics, a clinical-stage biotechnology company, to use tumour cell lines, patient-derived tumour organoids/tumour explants/fragments (PDE/PDTFs) and matched PBMCs to comprehensively assess the efficacy of the next-generation TCR-T therapies for solid cancers such as colorectal and other cancers as specified (Non-small cell lung cancer, Pancreatic cancer, Triple-negative breast cancer, Head and neck squamous cell carcinoma, Cervical carcinoma, Renal cell carcinoma, Ovarian cancer) offering valuable insights for future research and clinical applications. Role Summary You will provide technical expertise, support and guidance in research support. You may supervise a number of technical staff but even where you do not directly supervise staff you will still be expected to act as a role model and coach others as appropriate. You will need an in-depth understanding of the techniques and experimental protocols. Experience of cancer cell models would be preferable. You will be able to use your in-depth knowledge to advise on procedures, diagnose and resolve problems, and proactively suggest solutions to issues which arise. You may need to operate out of normal working hours to accommodate experimental procedures. In order to flexibly use resource you may be offered the opportunity to work in different areas of the Institute or College or wider university. Main Duties The role holder will provide support for the research undertaken by Professor Beggs using a variety of techniques to include, but not exclusively: Derivation and maintenance of organoid culture models and tumour fragments in culture. Drug screen of organoid models with immune cell co-culture and tumour fragments. PBMC isolation. Flow Cytometry. Live Imaging. CRISPR/Cas9 methodologies. You will use your in-depth knowledge of methods and procedures to advise on techniques and experimental procedures being used by researchers and/or students. Work to deadlines imposed by the PI or nominee and provide consistent results delivery. Communicate results to colleagues. You will be responsible for assisting in managing the experimental laboratories. You will use your in-depth knowledge of methods and procedures to advise on techniques and experimental procedures being used by researchers and/or students. This will involve communicating with colleagues at a range of levels and inexperienced students. You will need to be able to diagnose and resolve problems and suggest solutions in regard to techniques and experiments. Carry out specialist technical and experimental procedures which will need you to use your judgment to assess the correct technique to use, and to consider how these may be improved, referring to your manager for approval on any proposed changes. You will need to maintain accurate records of all techniques and experimental procedures you carry out, and for any other research activities you may be involved in including methodology and results. Ensure compliance with legislation relevant to the area of research activity. Comply with and promote the operating procedures for the area, including the classification, labelling and packaging of substances and mixtures regulation. You may contribute to internal and external audit procedures and to regulatory inspections. Health and Safety duties Proactive support for health and safety within the laboratory. This may include being required to look after a communal area as part of your duties. Comply with all current rules and ensure all required assessments are in place, approved and up to date. Fully understand the safety aspects of equipment operation and be able to demonstrate/train staff (at all levels) on the correct usage of the equipment. Ensuring that regular maintenance processes are carried out and that appropriate records are maintained. Reporting any breaches or non-compliance with H&S procedures to the relevant manager(s). Upholding the correct waste disposal stream as governed by College and local policy for laboratory. Post holders may be asked to undergo training as a First Aider or Fire Warden. General Administration and Organisation Ensuring all records are accurate and kept up to date. Proactively maintain stocks of consumables, and when required generate purchase order requisitions using University systems. Receipt and correct storage of consumables/equipment and chemical reagents. Ensuring that the facilities are maintained in a clean, functional and safe condition, reporting any problems through the appropriate channels. Ensuring that PAT testing, calibration of equipment and locally and centrally held equipment inventories are up to date and maintained. Adopt a proactive attitude to assisting with and implementing carbon reduction and energy saving measures. Other Duties In collaboration with the relevant manager the post holder will take an active role in the training and mentoring process for junior or newly appointed staff. Supports equality and values diversity, moderates own behaviour to avoid unfair discriminatory impact or bias on others. Any other duties as may reasonably be required. Required Knowledge, Skills, Qualifications, Experience  Extensive relevant workplace experience, equivalent professional qualification or degree in an appropriate subject. GCSE level 2 (A*- C) or equivalent level 2 qualification in mathematics and English. In-depth practical knowledge of relevant technical and scientific methods stated above. Extensive proven experience of similar laboratory based work, together with familiarity with a wide range of laboratory equipment. Positive service attitude and shows courtesy in dealing with others. Ability to organise and manage own work load and demonstrate flexibility in terms of work practices/requirements. Ability to work under minimal supervision but function as part of a team. Knowledge of current legislation relevant to the role. Knowledge of current H&S policies and ability to uphold same. Understanding of the Human Tissue Act and working to GLP standards. Proficiency in commonly used software packages. Understands the importance of equality and diversity in the workplace. Ability to identify and respond

Research Fellow in Plant and Soil Microbiology

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Applications are invited for a Postdoctoral Research Fellow to join the School of Biological Sciences at the University of Southampton. The School hosts a vibrant, interdisciplinary research community addressing global challenges at the interface of biodiversity, agriculture, and society. You will work on a Leverhulme Trust–funded project investigating the ecological and socio-economic importance of bat guano in Mexico. The project integrates bat ecology, cave ecosystems, microbiology, plant biology, and social science to understand how this under-recognised natural resource supports agriculture and rural livelihoods, and how it can be managed sustainably. The role  The post is funded by the Leverhulme Trust as part of the project “Quantifying the socio-economic consequences of losing bat guano services”, awarded to Dr. Veronica Zamora-Gutierrez, Dr. William L. King, and Dr. Kelvin Peh, with lead-supervision by Dr. King. The position is fixed for 36 months (3 years). The postholder will lead research on assessing the impacts of bat guano on crop growth and physiology, soil health, and plant and soil microbiology. This will include performing fertilisation experiments, measuring plant traits, including above-ground and below-ground, and the collection and analysis of plant and soil microbiomes. The role involves extended fieldwork in Mexico and close collaboration with UK- and Mexico-based partners, conservation organisations, and government agencies. You will contribute to high-quality academic publications, policy-relevant outputs, and stakeholder engagement activities. About you You will hold a completed PhD in environmental microbiology, microbiome science, environmental science, or a related discipline. You will have demonstratable experience in field-based research, microbiology (field and laboratory), bioinformatics (e.g. metagenomics and high-performance computing), and handling plants and soil, particularly roots (i.e. rhizosphere collection and root traits). You will have a strong interest in environmental microbiology, plant-microbe interactions, and agriculture. You will be comfortable working independently and collaboratively within an interdisciplinary team and engaging with non-academic stakeholders. You will have excellent written and verbal communication skills in English, with the ability to contribute to peer-reviewed publications and project reports. Spanish language skills are not essential but would be helpful. You should be willing and able to undertake extended international fieldwork and work across cultural and disciplinary boundaries. You will be based at the University of Southampton’s Highfield Campus, in a dynamic and well-connected coastal city. What we can offer you As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. With a generous holiday allowance as well as additional university closure days we are committed to supporting our staff and students and open to a flexible working approach. If you wish to discuss the role in more detail, please email Dr. William L King (W.L.King@soton.ac.uk). Working at the University of Southampton: Check out the staff benefits and why you should join us at The University of Southampton. Further details: Job Description and Person Specification We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity. Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number. Apply Now

Position for Research Fellow

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About the Role   Informal Queries For informal queries, please contact Professor Tim Bugg at t.d.bugg@warwick.ac.uk This research fellow position is funded by a NSF-BBSRC CIRCLE Network, a network of research groups in USA, Canada, UK, Korea and Australia, working on new biotechnological solutions to sustainable chemicals production from plant biomass. This position is available for 12 months starting from 1st July 2026, working in the research group of Prof T D H Bugg, in the Chemical Biology Research Cluster in the Department of Chemistry at University of Warwick. The project will involve screening of metagenomic libraries for new biocatalysts for lignin bioconversion, and enzymology studies on the new enzymes identified. About You   Applicants should have a PhD in Biochemistry, Biotechnology, Biological Chemistry or Microbiology, and should have a track record of publications in relevant scientific areas, and a track record of successful project completion. The successful candidate must have research experience of working with enzymes, and experience in molecular genetics, including bacteria other than Escherichia coli (the microbe to be used is Pseudomonas putida KT2440), and experience of working with micro-organisms other than Escherichia coli. The applicant should have experience of carrying out biotransformations using enzymes and/or engineered microbes. Experience in bio-analytical methods such as HPLC or LC-MS would be highly desirable. The applicant should be able to work independently, and to plan, execute and deliver new experimental ideas, using the research literature as needed. They should be able to write up and present their research clearly, to internal and external audiences, and they should interact positively with a research group, taking on responsibilities within the group. They will report regularly on progress to Prof. Bugg, and attend regular meetings with project partner groups in the UK and overseas. You must be able to work without supervision, using good laboratory practice. If you have not yet been awarded your PhD but are near submission or have recently submitted your PhD, any offers of employment will be made as Research Assistant on level 5 of the University grade structure (£34,610). Upon successful award of your PhD and evidence of this fact, you will be promoted to Research Fellow on the first point of the level 6 of the University grade structure (£35,608). For details on the experience and skills required, please refer to the job description attached as a PDF below. PhD Status If you are near submission of your PhD, or have not yet had it conferred, any offers of employment will be made at Research Assistant level, at the highest spinal point of pay grade 5 (£34,610 per annum). Upon receipt of evidence confirming the successful award of your PhD, you will be promoted to Research Fellow, at the lowest spinal point of grade 6 (£35,608 per annum). About the Department   The Department of Chemistry at Warwick is a thriving community of students, academics, researchers, and support staff. Our fundamental research pushes boundaries in all major fields of Chemistry. Through collaborations with the wider science community and industry, our applied work aims to tackle huge global issues from antimicrobial resistance, to solar energy harvesting, and sustainable materials. We provide an inclusive, vibrant and friendly environment where our students have dedicated support to explore their passion for chemistry. Athena SWAN Silver Award We are committed to supporting staff to achieve their potential. Both the Department of Chemistry and the University of Warwick hold Athena SWAN silver awards, a national initiative that recognises the advancement of gender equality, representation, progression, and success for all in academia. We provide a welcoming and inclusive working and learning environment, recognising that everyone is different in a variety of visible and non-visible ways, and that those differences are to be recognised, respected, and valued. We welcome applications from individuals who identify with any of the protected characteristics defined by the Equality Act 2010. We are supportive of staff with caring responsibilities. About the University   We are a world-leading research-intensive university founded in 1965. We are ranked 106th in the world and 8th in the UK.* Additionally, 92% of our research is rated world-leading or internationally excellent.** Find out more about us at warwick.ac.uk/about/. * World University Ranking 2024, Guardian University Guide 2025 ** Research Excellence Framework 2021 How to Apply   CLOSING DEADLINE: Wednesday 18th March 2026 at 11:55pm (UK Time) To apply, please click “Apply” below and submit an application form by the closing deadline. You will be asked to include a CV and a cover letter. Your CV should include: Your education and employment history (including your most recent employment). Any other relevant experience (e.g. volunteering, extracurricular, etc.). Your cover letter should explain: Your motivations for applying to the role. Using examples, how you meet the essential and desirable criteria detailed in the job description (PDF attached below). All essential criteria must be met by candidates who are invited to interview. You are welcome to include details of any career breaks (e.g. parental leave, caring responsibilities, sick leave). Interview Date: To be confirmed Start Date: 1st August 2026 Please note application forms must be submitted before the stated deadline – you will not be able to submit after 23:55 (even if you opened the form earlier). Only applications submitted via our official careers portal (warwick-careers.tal.net) will be considered. What we Offer   We provide a comprehensive range of benefits, including: An attractive pension scheme. 30 days holiday plus University Christmas closure. Generous parental/adoption leave policy. Onsite childcare facilities. Excellent learning and development opportunities. We recognise the importance of a healthy work/life balance and offer access to flexible working arrangements. For more information, see here. We are proud to be a Living Wage employer. Our Commitment to Inclusion   Equality, Diversity, & Inclusion Warwick is committed to fostering a diverse, inclusive and respectful community where everyone can thrive. We welcome applications from all backgrounds, cultures, and communities, and actively encourage candidates from underrepresented groups to apply. Find out more about our Social Inclusion work at Warwick. Find out more about our awards and accreditations. We are also one of the six founder institutions of the EUTOPIA European University Alliance. Safeguarding & DBS The University of Warwick is committed to safeguarding and promoting the welfare

Research Technician in Cancer Nanotherapeutics

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About the role: We are seeking an enthusiastic, organised, and highly committed laboratory-based Research Technician to join the Nanotherapeutics Lab as part of a newly funded Cancer Research UK (CRUK) research programme. This role offers an exciting opportunity to contribute to cutting-edge work at the interface of neuro-oncology, nanomedicine, and translational cancer research, within a programme with clear clinical relevance and long-term ambition. The Research Technician will provide essential technical support across a range of project-specific research activities. These will include cell culture (primary cultures, stem cells, and cancer cell lines), tissue processing and histology, immunohistochemistry and immunoassays (e.g. ELISA), and microscopy techniques including fluorescence and confocal imaging. The role will also involve supporting in vivo animal studies, including routine monitoring and the performance of procedures in accordance with relevant licences and regulations. The successful candidate will join the Nanotherapeutics Lab, a diverse and highly collaborative multidisciplinary team based within the Division of Neuroscience at the University of Manchester. The lab is closely embedded within the Centre for Nanotechnology in Medicine, the Geoffrey Jefferson Brain Research Centre, and the Manchester Cancer Research Centre, providing access to a unique ecosystem of expertise in neuroscience, cancer biology, imaging, nanotechnology, and translational research. The research environment is fast-moving, collaborative, inclusive, and supportive of career development. This CRUK-funded position is full-time (1.0 FTE) for 2 years in the first instance, with funding and the possibility in place to extend for up to 6 years, subject to progress. What you will get in return: Fantastic market leading Pension scheme Excellent employee health and wellbeing services including an Employee Assistance Programme Exceptional starting annual leave entitlement, plus bank holidays Additional paid closure over the Christmas period Local and national discounts at a range of major retailers, and more. As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit. Our University is positive about flexible working and you can find out morehere. Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies. Any recruitment enquiries from recruitment agencies should be directed to recruitmentservices.people@manchester.ac.uk. Any CV’s submitted by a recruitment agency will be considered a gift. For enquiries on vacancy, shortlisting and interviews: Informal enquiries can be made to Dr Thomas Kisby. Email: thomas.kisby@manchester.ac.uk General enquiries: Email: recruitmentservices.people@manchester.ac.uk Technical support: https://jobseekersupport.jobtrain.co.uk/support/home Please quote reference BMH-030932 This vacancy will close for applications at midnight on the closing date. Apply Now

Postdoctoral Research Associate in quantitative genetics and breeding

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The Opportunity: We are looking to fill a post for Postdoctoral Research Associate in quantitative genetics and breeding within the project OptiME. In this role, you will advance the state-of-the-art view on how to deploy genome editing in plant breeding programmes for simple and complex traits, including evaluating potentials, bottlenecks, and novel methods of prioritising targets for genome editing. You will work as part of a worldwide team of professional contacts in plant breeding and genome editing community. This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working, all based in the UK Your skills and attributes for success:  You are passionate about quantitative genetics or breeding You have experience in a high-level programming language You are interested in evaluating novel quantitative and genome editing methods and how they could be used in practical settings You are independent, organised, and thrive in collaboration with multidisciplinary teams working in globally important sector Please inspect the call documentation regarding the essential and desirable knowledge, skills and experience needed for the post Click to view a copy of the full job description  Application Information Please ensure you include the following documents in your application: – CV – Cover letter As a valued member of our team you can expect: Exciting opportunity to collaborate with professional contacts in plant breeding and genome editing community A competitive salary of £41,064 to £44,746 per annum. An exciting, positive, creative, challenging and rewarding place to work. To be part of a diverse and vibrant international community Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page and use our reward calculator to discover the total value of your pay and benefits Championing equality, diversity and inclusion The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality. Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages The University may be able to sponsor the employment of international workers in this role. This will depend on a number of factors specific to the successful applicant. Key dates to note The closing date for applications is 13 March 2026. Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone. Interviews will be held a week or two after the closing date for applications, with planned starting date as soon as possible in 2026. Apply Now

Position for Research Fellow

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About us The Sainsbury Wellcome Centre (SWC) brings together world-leading scientists to investigate how brain circuits process information to generate perception, form memories and guide behaviour. Developed through the vision and partnership of the Gatsby Charitable Foundation and Wellcome, and with substantial investment from these partners, the mission of the SWC is to generate experimentally testable theories of brain function. The Centre will comprise around 14 highly interdisciplinary experimental research groups accommodated in a new, purpose-designed building, offering an outstanding and unparalleled research environment. SWC scientists use a broad spectrum of the latest advances in molecular and cellular biology, imaging, electrophysiology and behavioural techniques and enjoy state-of-the-art research laboratories, cutting-edge scientific equipment, technologically-advanced prototyping and fabrication laboratories and custom in-house high-performance computing facilities. The Harris Lab is interested in one of Biology’s biggest mysteries – why do brains need to sleep? We investigate single cell and neural circuit changes during sleep, with a focus on how these changes impact both neural computation and energy use, allowing us to wake up each morning with brains that are increasingly optimised for our environment. We work with mice, using a combination of electrophysiological and optogenetic techniques alongside olfactory behavioural paradigms to study changes in learning, memory and sensory processing across arousal states. About the role We are looking for an excellent Postdoctoral Research Fellow to join a joint project between the labs of Sonja Hofer and Tim Behrens at the Sainsbury Wellcome Centre (SWC). The goal of this project is to determine how neocortical and subcortical circuits interact to mediate flexible behaviour. The project will focus on the neural circuit mechanisms underlying goal switching and behavioural strategy selection, by mapping algorithmic theories of behaviour onto specific microcircuits and pathways. The applicant will use a multidisciplinary approach including in vivo imaging, high-density electrophysiological recordings (e.g. Neuropixels), behavioural assays, and molecular and genetic tools to record from, manipulate, and trace defined neural populations, with particular emphasis on interactions between the median raphe nucleus, frontal cortex, and hippocampus. About you We are looking for a highly motivated postdoctoral researcher with a PhD in neuroscience or a related field (or who will have submitted their thesis prior to starting), and a strong interest in understanding neural circuits and behaviour. The successful candidate will have experience in rodent-based research, including handling, stereotaxic surgery, behavioural training, and neural circuit dissection techniques, as well as experience with in vivo electrophysiological recordings or imaging approaches with single-cell resolution. The postholder will be expected to design and drive independent research projects, contribute original ideas for new research directions and funding applications, and analyse complex datasets using programming tools such as Python, R, or MATLAB, supported by a solid understanding of statistics. Excellent written and oral communication skills are essential, with the ability to write for publication and present research clearly. The role requires strong organisational skills, the ability to manage multiple activities in parallel, a collaborative and ethical approach to research, and motivation to contribute to the mission and research environment of the Sainsbury Wellcome Centre as a world-leading research institute. This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa What we offer The SWC offers staff an award-winning work environment in the heart of Fitzro via with an onsite brasserie, access to lockers and changing facilities, secure bicycle storage, and access to pleasant outdoor spaces. The Centre also offers the full range of UCL staff benefits, including a generous annual leave entitlement, occupational pension schemes, excellent family-friendly policies such as occupational shared parental pay, a work-life balance policy, and a range of financial benefits such as a season ticket loan scheme and staff discounts. Our commitment to Equality, Diversity and Inclusion As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. The Athena SWAN Charter recognises commitment to advancing women’s careers in science, technology, engineering, maths, and medicine (STEMM) employment in academia. SWC is delighted to have received an Athena Swan Bronze Award in 2021. We stand by our commitment to positive action to improve equality and accessibility in the workplace. We will provide reasonable adjustments to enable people to work and flourish with us. SWC is proud to uphold both UCL’s Dignity at Work and Work-Life Balance policies. As Centre we commit to fostering a positive cultural climate where all staff and students can thrive and and actively support Wellbeing@UCL, UCL community, supported by our Wellbeing. Available documents Attached documents are available under links. Clicking a document link will initialize its download. Download: Job Description Person Specification_ Research Fellow_2026.Pdf Apply Now

Position for Research Assistant

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About the role We are looking for a Research Assistant to work on a project within the Centre for Inflammatory Disease, in the Department of Immunology and Inflammation, at Imperial College London. This post is funded by UKRI and is part of a long-term research program focused on human systems immunology and commensal-specific immune responses. This post is within Professor Petter Brodin’s group, whose laboratory focuses on the development of the immune system in early life. The team also studies variation in immune responses in health and disease, including sex differences, the effects of sex hormones on immune function, the regulatory mechanisms underlying such variation, and how the immune system adapts to environmental influences. The Centre for Inflammatory Disease (CID)at Imperial College London is a multidisciplinary hub focused on understanding the mechanisms driving inflammation and translating this knowledge into new therapies. It brings together clinicians and scientists across immunology, rheumatology, nephrology, gastroenterology, and respiratory medicine. The Centre integrates basic science with clinical research to tackle chronic inflammatory and autoimmune diseases. Through cutting-edge approaches—such asgenomics, single-cell analysis, and translational immunology—CID plays a leading role in advancing personalized medicine and improving outcomes for patients with inflammatory conditions. What you would be doing You will provide technical support  and conduct experimental work within the GIFT study (Gender Affirming Hormone Therapy and Immune Function in Trans Individuals) to determine immune system adaptation during sex-hormone treatment. More specifically, you will assist with blood sample collection from a transgender health clinic, sample processing, and perform exciting experiments such as whole blood stimulation cultures and fixation procedures, ELISA/SIMOA, and analysis by high-dimensional spectral flow cytometry. A particular focus will be on commensal-specific immune responses and their regulation by sex-hormones. What we are looking for MSc in a relevant discipline like Biology, Biotechnology, or equivalent research, industrial or commercial experience Knowledge of research methods and statistical procedures Prior experience in flow cytometry, SIMOA, cell cultures, and handling blood samples Practical experience within a research environment and / or publication in relevant and refereed journals Ability to understand, develop and innovate methods What we can offer you Professor Brodin’s group is internationally renowned for their research on experimental and computational methods for systems-level analyses of the human immune systems. This research provides a great opportunity for those interested in a career in immunology research. The opportunity to continue your career at a world-leading institution and be part of our mission to use science for humanity. Grow your career: gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression. Benefit from sector-leading salary and remuneration package (including 41 days off a year and generous pension schemes). Gain access to a range of workplace benefits including a flexible working policy from day one, generous family leave packages, on-site leisure facilities and a cycle-to-work scheme. Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing. Further information Imperial Expectations guide the behaviour of all our staff. This is a full-time post available until 31 December 2029. If you require any further details about the role, please contact: Prof. Petter Brodin – Email: p.brodin@imperial.ac.uk. Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above. We reserve the right to close the advert prior to the closing date stated should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment. If you encounter any technical issues while applying online, please don’t hesitate to email us at support.jobs@imperial.ac.uk. We’re here to help. Apply Now

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