Fixed-term

JOB DESCRIPTION Grade UE07: £41,064- £48,822 per annum College of Medicine and Veterinary Medicine/School of Neurological and Cardiovascular Sciences/Institute for Neuroscience and Cardiovascular Research Full-time: 35 hours per week, 100% on-site Fixed-term: for 36 months The Opportunity: This is an exciting opportunity to work in a dynamic translational research lab that has expertise in working with organoids. The position is for a senior post-doctoral research scientist and is focused on supporting the development of a novel cardiac drug screening platform, with the primary responsibility being the generation of human stem cell–derived (iPSC) cardiospheroids, subsequent biochemical and molecular testing and engagement with the development of a commercialisation strategy. The post is based at the University of Edinburgh, and the post-doctoral research scientist will work under the guidance of Professor Shareen Forbes. The post-holder will produce and test the cardiospheroids using the novel biomedical instrument developed which is currently at the prototype stage which has been designed by the investigators to overcome bottlenecks in screening for drug-induced cardiac arrhythmias. Testing will include comparison of biochemical and molecular status with electrical responses from the cardiospheroids with standard electrophysiological measurements and other modalities working alongside electrophysiologists.  Following drug exposure and manipulation cardiospheroids will be further assessed with downstream analyses using a range of molecular/cellular techniques. The post holder will work closely with engineers at Heriot-Watt University (Dr Euan Brown) and scientists in drug discovery (Professor Neil Carragher) and their respective teams in order to support the further development of the device for commercial readiness including the development of the device with an automated throughput system for cardiospheroid handling. The role also includes participation in the implementation of a Quality Management System to ensure ISO compatibility. The post-doctoral research scientist will contribute to report writing, IP reviews, business planning, and regulatory documentation, working alongside experts in commercialisation and regulatory development. The position is supported by a British Heart Foundation Translational Award to develop a diagnostic platform for screening new drugs for cardiac arrhythmias, with the goal of commercial readiness. The project offers a unique opportunity for a senior researcher to understand the steps necessary for successful commercialisation. The laboratory also hosts projects funded by charitable foundations and industry, including work on stem cell–derived islets, and comprises a multidisciplinary team of post-doctoral researchers, clinician scientists, technicians, coordinators and PhD students. Your skills and attributes for success: Experience in stem cell organoid generation. Experience in a wide range of molecular biology techniques, imaging software and statistical skills. Ability to work in a team and communicate ideas well between disciplines. Ability to think critically and direct own research independently. Record of publications. Diverse career opportunities With roles from hospitality to research, there’s a career for everyone at the University of Edinburgh. We can offer opportunities for you to develop in your career and make a real difference in the communities around us while contributing to the world at large. Roles for every stage of your career We offer careers and roles in just about every area you can think of. Whether you are looking for entry-level, mid-career or roles at the top of your chosen specialism, we can offer you a career where you can flourish and make a real difference in the communities around us while contributing to the world at large. Our people come from a wide range of backgrounds, each bringing their abilities and experiences to our organisation. A unique employer in a vibrant city The University isn’t just any employer. We are part of a local community and a contributor to global thinking, progress and research. In Edinburgh, you are in one of the world’s most attractive cities with active arts and social sectors, while working in a University that has made significant contributions to society, medicine, physics and teaching for over four centuries. Our people have helped create the modern world and are working on more ground-breaking technologies and practices. Make a meaningful impact Join the University of Edinburgh and you’ll be making a difference to everything around you. Be part of something bigger — where you’ll do meaningful work, grow and progress, be rewarded and recognised, and benefit from our strong commitment to your wellbeing. There are so many reasons to join us. Job type: Academic People have always been at the heart of our work. As part of the University, you are a part of our community. We are looking for people with drive, determination, and a passion for what they do. We are a place where everyone is welcome and offer a range of policies and benefits designed to support you in building the right meaningful/personalised flexibility for you. View the full job description.  How to apply Please include the following documents in your application: – CV – Cover letter Informal enquiries are welcomed and can be addressed to Professor Shareen Forbes, Shareen.Forbes@ed.ac.uk  As a valued member of our team, you can expect:  A competitive salary. An exciting, positive, creative, challenging and rewarding place to work. To be part of a diverse and vibrant international community. Comprehensive Staff Benefits, including generous annual leave entitlement, a defined benefits pension scheme, a wide range of staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our staff benefits page and use our reward calculator to discover the value of your pay and benefits. Championing equality, diversity, and inclusion The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter, and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality. We welcome applications from all qualified candidates. Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages. On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK. Key dates to note The closing date for applications is 13th April 2026. Unless stated otherwise the closing time

Faculty of Biology and Biotechnology :Department of General Zoology and Neurobiology  In order to fill a fixed-term position in part-time (25.8895 hours/week = 65%) 01.09.2026, we are looking for 10 PhD candidates (m/f/x) at Research Training Group “Monoaminergic Neuronal Networks & Disease” The Research Training Group Monoaminergic Neuronal Networks & Disease (MoNN&Di) is inviting applications for 10 PhD positions, starting in September 2026. The projects of our program investigate monoaminergic neuronal networks in healthy brain function and examine how their dysfunction contributes to neurodegenrative, movement and neuropsychiatric disease. Through close interdisciplinary collaborations across the fields of biology, biotechnology, medicine and computer science, we will train doctoral candidates to become the next generation of highly skilled researchers who can bridge the gap between tool development, basic research and clinical applications.   Your tasks: design and conduction of experimental studies application/development of neurobiological, molecular, electrophysiological or imaging methods analysis and statistically evaluation of experimental data documentation, interpretation and presentation of research findings active participation in seminars, lab meetings and scientific conferences Your profile: completed Master’s degree (M.Sc.) in Biology, Biochemistry, Neuroscience, Psychology or a related discipline strong interest and solid background in neurobiological research, particularly in monoaminergic systems advanced laboratory experience excellent written and spoken English skills We offer: a structured doctoral training program an interdisciplinary and international research environment closed supervision by a thesis committee international exchange with leading neuroscientists Further information: The position is salaried and based on the collective agreement of the Länder (TV-L). If the personal and collective agreement requirements are met, the employee will receive pay grade E13 TV-L. Further information can be found at https://oeffentlicher-dienst.info/ (in German). The place of work is Ruhr University Bochum. If the position is funded by third-party funds the employee has no teaching obligation. Application Requirements: the completed application form (to be found at https://www.ruhr-uni-bochum.de/monndi/), a Curriculum Vitae (CV), two letters of recommendation, certified copies of Master’s degree including transcripts RUB sees itself as a university with an international presence. The campus languages are German and English. Competence in at least one of the two languages and the willingness to learn the other are a prerequisite. RUB provides corresponding free courses for employees.  German language courses are offered by the University Language Center (ZFA) in the field of German as a Foreign Language (DaF). https://www.daf.ruhr-uni-bochum.de/sbgk/index.html.en The Staff Council has the right to participate in all selection interviews. At the request of a candidate (m/f/x), it will ensure its participation in the entire procedure. Please contact wpr@rub.de. The Ruhr-Universität Bochum is one of Germany’s leading research universities, addressing the whole range of academic disciplines. A highly dynamic setting enables researchers and students to work across the traditional boundaries of academic subjects and faculties. To create knowledge networks within and beyond the university is Ruhr-Universität Bochum’s declared aim. The Ruhr-Universität Bochum stands for diversity and equal opportunities. For this reason, we favour a working environment composed of heterogeneous teams, and seek to promote the careers of individuals who are underrepresented in our respective professional areas. The Ruhr-Universität Bochum expressly requests job applications from women. In areas in which they are underrepresented they will be given preference in the case of equivalent qualifications with male candidates. Applications from individuals with disabilities are most welcome. Contact persons for further information: Dr. Michelle Grömmke +49 234 32 24358Prof. Dr. Stefan Herlitze +49 234 32 24363 Travel costs, accommodation costs and loss of earnings or other application costs for job interviews can unfortunately not be reimbursed. We look forward to receiving your application via our online application portal by 2026-03-31. Please make sure to mention the reference number ANR 5456. Apply Now

Intracellular commensal and pathogenic microbes utilize and invade the cellular systems of their hosts to ensure their survival, replication, and spread. The relative simplicity of many microbes and the ability to genetically manipulate them have made them ideal model systems for analyzing fundamental cellular, biological, and neurological processes, including cell death and innate immunity. Interdisciplinary research, the integration of state-of-the-art cellular, immunological, and neurological model systems, and advanced technological approaches offer the potential to deepen our understanding of host-pathogen interactions, with a particular focus on hepatitis E viruses, at the translational level in this field. Furthermore, the role of understudied molecular and cellular effectors in encounters with both commensal and pathogenic microbes will be elucidated to identify potential targets for the development of novel therapeutics. Taken together, these efforts contribute to expanding our understanding of the dynamic interplay between host and microbe and to developing new approaches for combating and eliminating pathogens. The focus is particularly on the following research questions at the interface of host-microbe interactions and their intervention: • Research and translation of antiviral drugs, in particular through the development of agents against hepatitis E viruses that either directly target viral targets or relevant host processes. • Investigation of mechanisms of antiviral therapies and resistance development against the hepatitis E virus in order to enable more effective long-term intervention strategies. Furthermore, the successful candidate will be expected to integrate into the faculty’s research priorities (oncology, neuroscience, and protein science). Clinical and scientific collaborations with institutions of the Faculty of Medicine and the University Hospital Ruhr (UK RUB) in existing research priorities and development areas, as well as participation in existing and future collaborative research projects, are desirable. The appointment is initially for a fixed term of three years. Following a positive evaluation, an extension for a further three years is planned. Requirements A doctorate of outstanding quality and proof of exceptional aptitude for academic teaching are required, as is a willingness to participate in academic self-governance. The appointment requirements according to § 36 ff. of the North Rhine-Westphalia Higher Education Act must be met. Furthermore, the following are expected: a high level of commitment to teaching; the willingness to engage in interdisciplinary scientific work; the willingness and ability to acquire third-party funded research projects; the willingness and ability to promote contract research and industry collaborations; Sound knowledge in drug discovery, in particular the development of direct and host-targeting antiviral substances and the investigation of resistance mechanisms; Extensive experience in authentic cell culture models (including primary human and animal hepatocytes) Contact persons for further information: Prof. Dr. Eike Steinmann Tel.: +49 234 32 23189. We look forward to receiving your application, quoting reference number 5399, via our online application portal. Apply Now