Fixed-term

NERC RED-ALERT CDT: Impact of Sewage on Antimicrobial Resistance (AMR) and Pathogens in River Environments.

Details This project is one of a number that are in competition for funding from the Red-ALERT CDT, awarded by Cardiff University , and hosted and lead supervised from UKCEH, for entry in September 2026. Overview of the Research: This exciting and collaborative PhD project will apply cutting-edge molecular techniques to explore the potential contribution of untreated wastewater to the dissemination of antimicrobial resistant (AMR) organisms and key human pathogens in rivers. AMR is a major global public health threat, with bacterial resistance alone estimated to have caused 1.27 million deaths worldwide in 2019. Aquatic ecosystems increasingly act as reservoirs for resistant microbes, resistance genes, and pathogenic organisms, exacerbating the spread and impact of AMR. The PhD project will be hosted at the UK Centre for Ecology and Hydrology (UKCEH), Wallingford, in collaboration with Cardiff University, and our project partners Welsh Government, Dŵr Cymru Welsh Water, and UKHSA. Wastewater treatment plants (WwTPs) play a vital role in mitigating pollution from human activities and protecting both environmental and public health. However, untreated wastewater can still enter rivers through combined sewer overflows (CSOs) and misconnections to drainage infrastructure. The influence of these inputs on the prevalence and spread of AMR and pathogens in rivers remains poorly characterised. To understand the dynamics of AMR and pathogen dissemination from wastewater into receiving environments, this PhD will employ advanced molecular methods in a catchment-based approach within the Taff and Ely catchments. By integrating advanced omics technologies, including metagenomic sequencing, with field-based sampling and water quality monitoring, the project will generate critical insights into how releases of untreated sewage and misconnections influence water quality, and resistance gene and pathogen distribution and abundance. The findings will inform evidence-based strategies to mitigate the risks associated with waterborne AMR and pathogens, contributing to improved management of wastewater systems and enhanced protection of environmental and human health. Training: The student will gain comprehensive training in molecular approaches (DNA extraction, PCR, sequencing library prep/data processing), experimental design, catchment-scale analysis, data visualisation, statistics, scientific writing, and presenting. The student will also participate in opportunities at host and partner organisations and will benefit from the broader Red-ALERT CDT training programme. Welsh Government and DCWW will provide CASE partnership, including co-supervision, policy and technical support and guidance, access to sites for in situ sampling, and an opportunity for a placement. UKHSA will provide support and guidance in subject matter expertise and policy relevance.  Interdisciplinarity: The supervisory team combines experts from academia and industry, spanning water quality and environmental pollution, genomics, and microbial community ecology and ecosystem health. Addressing the complex interactions between untreated wastewater and the spread of AMR and pathogens in rivers requires a broad analytical perspective, drawing on complementary scientific approaches. Project Keywords: Antimicrobial resistance (AMR), pathogens, wastewater, combined sewer overflows (CSOs) Industrial Partner: Dŵr Cymru, Welsh Water and Welsh Government Candidate Requirements: Applicants should hold, or expect to receive, a First Class or good Upper Second-Class UK Honours degree (or the equivalent) in a relevant subject e.g. biology, molecular or microbiology, chemistry, biochemistry, etc. Academic qualifications are considered alongside significant relevant non-academic experience. A master’s level qualification would also be advantageous. Equality, Diversity, and Inclusion: We value a diverse research environment and aim to be an inclusive university, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups. If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement. Enquiries and Applications: Formal applications should be submitted via the Red-ALERT CDT online application form prior to the closing date of this advert. Funding Notes Candidates may be considered for a NERC Red-ALERT studentship tenable for 3.5 years. Funding covers tuition fees, a stipend (£21,805 p/a in 2026/7) and access to a training support budget.

NERC RED-ALERT CDT: Nano-Virus: Developing novel real-time rapid and sensitive detection of viruses in water and wastewater.

Details This project is one of a number that are in competition for funding from the Red-ALERT CDT, hosted by Cardiff University for entry in September 2026. Overview of the Research: Detection of viruses in water and wastewater using DNA/RNA methods is well-established, and since the COVID-19 pandemic has been the focus of a much-increased global research effort related to (waste)water-based epidemiology (WBE).  These studies have focused particularly on molecular detection of viruses such as SARS-CoV-2, influenza virus, RSV and norovirus, but often lack information on virus infectivity. Current methods for detection of the virion (i.e. the infectious virus particle) detection methods are neither rapid nor sensitive. This project explores using nanodiamond-coated quartz microfiber membranes to concentrate virions from water samples and nanobody biosensors (carbon nanotubules with capsid-specific antibodies). The overall project aims are: (1) to enhance speed and sensitivity in detecting specific viruses, focusing on noroviruses for which nanobodies have already been developed, and (2) to assess the potential of this approach for real-time, rapid, and highly sensitive virus detection in water and wastewater. Extraction and concentration of viruses using nanodiamond technology and the nanoscale sensor have already been described by our group (for underlying concepts see Bland et al., 2021, https://doi.org/10.1021/acsanm.1c00439; Huang et al., 2025, https://doi.org/10.1038/s41467-025- 63192-w; Ahmed et al., 2025, https://doi.org/10.1038/s42004-025-01573-4). In this project these approaches will be developed to capture/detect active norovirus (specific nanobodies already constructed) in freshwater brackish water and wastewater. This virus has a large societal cost across the world, estimated at $65 billion, including ~US$5 billion in direct healthcare costs. In the UK alone, norovirus is the largest contributor (£1.7 billion) to the ~£9 billion cost burden of foodborne illnesses. Thus, early detection of norovirus will prevent major outbreaks. The sensitivity and speed of detection using this new approach will be compared with conventional molecular detection, e.g. by qPCR/sequencing approaches, already well established by the supervisory team at Cardiff and Bangor Universities. Training Provided: The project will provide extensive training in molecular and environmental microbiology/virology, biochemistry and aspects of ecology relevant to WBE/One Health. The student will have access to extensive laboratory and associated (e.g. high-performance computing) facilities in the Cardiff University-School-of-Biosciences. S/he will join the School’s PGR community in the Organisms & Environment-Division and the Microbiomes, Microbes & Bioinformatics Research Group, with full access to the School’s Technology Hubs. Interdisciplinarity: The project is highly interdisciplinary, involving supervisors based in the Schools of Biosciences (environmental microbiology/biochemistry), Physics (applied nanodiamond technologies) and Water Research-Institute (multidisciplinary) at Cardiff, and the School of Environmental & Natural Sciences at Bangor. In addition, the project will benefit from expert support of R&D and operations scientists at Dŵr Cymru/Welsh Water. Industrial Partner: Dŵr Cymru, Welsh Water Candidate Requirements: Applicants should hold, or expect to receive, a First Class or good Upper Second-Class UK Honours degree (or the equivalent) in a relevant subject – e.g. biomedical engineering, electronic engineering, chemistry, biochemistry, etc. Academic qualifications are considered alongside significant relevant non-academic experience. A master’s level qualification would also be advantageous. Equality, Diversity, and Inclusion: We value a diverse research environment and aim to be an inclusive Centre, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups. If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement. Enquiries and Applications: Formal applications should be submitted via the Red-ALERT CDT online application form prior to the closing date of this advert. Funding Notes Candidates may be considered for a NERC Red-ALERT studentship tenable for 3.5 years. Funding covers tuition fees, a stipend (£21,805 p/a in 2026/7) and access to a training support budget.

NERC RED-ALERT CDT: Real-time monitoring of fungi in freshwater systems.

Details This project is one of a number that are in competition for funding from the Red-ALERT CDT, hosted by Cardiff University for entry in September 2026. Overview of the Research: This project focusses on the role of fungi in freshwater systems, investigating nutrient dynamics and biogeochemical processes using real-time water quality monitoring approaches. The project will assess fungal diversity, fluorescence parameters, and nutrient drivers, via leveraging existing sensor networks on the Dart, living labs in the Taff and Ely, and established Thames catchment monitoring sites. In addition, lab-based microcosm experiments will explore fungal carbon processing and identify fluorescence indicators of ecosystem function. Ultimately, the industrial collaboration will help produce scalable, real-time monitoring solutions, to enhance spatial and temporal resolution of water quality data, contributing to improved freshwater management. Training: The successful candidate for the project will receive training in fieldwork; environmental sensing; mycology; freshwater ecology; fluorescence measurements; DNA barcoding; bioinformatics and statistical modelling. They will additionally benefit from joining the Cardiff Fungal Ecology lab group and receive training in skills such as literature searching, presentations, project management, etc. Interdisciplinarity: This project brings together topics in microbiology; ecology; biogeochemistry; engineering and statistics. Working at the interface of these disciplines is essential to understand the role of freshwater fungi and develop the technology needed to monitor them. Project Keywords: fungi; freshwater ecology; real-time monitoring; biogeochemistry; bioinformatics Industrial Partner: Chelsea Technologies Candidate Requirements: Applicants should hold, or expect to receive, a First Class or good Upper Second-Class UK Honours degree (or the equivalent) in a relevant subject e.g. biology and environmental science. Academic qualifications are considered alongside significant relevant non-academic experience. A master’s level qualification would also be advantageous. Equality, Diversity, and Inclusion: We value a diverse research environment and aim to be an inclusive Centre, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups. If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement. Enquiries and Applications: Formal applications should be submitted via the Red-ALERT CDT online application form prior to the closing date of this advert. Funding Notes Candidates may be considered for a NERC Red-ALERT studentship tenable for 3.5 years. Funding covers tuition fees, a stipend (£21,805 p/a in 2026/7) and access to a training support budget.

NERC RED-ALERT CDT: Tracking Toxicity: Assessing Pharmaceutical and Pesticide Mixtures in River Ecosystems.

Details This project is one of a number that are in competition for funding from the Red-ALERT CDT, hosted by Cardiff University for entry in September 2026. Overview of the Research: This Case PhD project in partnership with Natural Resources Wales (NRW) offers an exciting opportunity to develop next-generation tools for environmental monitoring by investigating the biological impacts of chemical mixtures in UK river systems. Focusing on the Taff and Ely catchments in Wales, the research will use cutting-edge Effect-Based Methods (EBM) to detect sub-lethal biological responses, such as endocrine disruption, oxidative stress, and genotoxicity in vitro, utilising the rainbow trout gill cell line RTgill-W1. These responses will be analysed using a multi-omics approach, integrating transcriptomics, metabolomics, and cytotoxicity assays to build a broad mechanistic understanding of pollutant effects. Environmental samples will undergo chemical fractionation and high-resolution mass spectrometry to identify active fractions responsible for biological changes. By combining Effect-Directed Analysis (EDA) with water quality data from Natural Resources Wales, the project aims to pinpoint key chemical drivers and assess the ecological relevance of complex pollutant mixtures. In parallel, laboratory experiments will expose the RTgill-W1 cell line to known neurotoxic pesticides (such as Diazinon, Fipronil, and Cypermethrin) both individually and in combination. These chemicals, frequently detected in Welsh rivers, pose significant risks to aquatic life. The project will assess additive, synergistic, or antagonistic interactions between these compounds, providing critical insights into mixture toxicity and informing future risk assessment frameworks. Training: This is a unique opportunity to shape the future of environmental protection in freshwater ecosystems. The student will receive comprehensive training in fieldwork, cell culture, toxicology, bioinformatics, and stakeholder engagement. They will develop skills in experimental design, data analysis, and scientific communication, including presenting at conferences and publishing peer-reviewed papers.  This interdisciplinary training will prepare them for impactful careers in environmental science and/or policy. While the core supervisors are experts in freshwater ecology, toxicology, cell culture and bioinformatics, they all engage in interdisciplinary research and therefore have wide professional networks that will support this studentship. Specifically, we will also work closely with biochemists, policy advisors and other experts at Natural Resources Wales. Interdisciplinarity: This project bridges ecotoxicology, molecular biology, and environmental chemistry, offering training in advanced cell culture techniques, omics technologies, and data integration. The outcomes will support policy development and regulatory innovation, contributing to more accurate and responsive water quality monitoring under frameworks like the Water Framework Directive. Project Keywords: Interdisciplinary, Environmental, Water Quality, Biochemistry, Omics Industrial Partner: Natural Resources Wales Candidate Requirements: Applicants should hold, or expect to receive, a First Class or good Upper Second-Class UK Honours degree (or the equivalent) in a relevant subject e.g. biology, environmental sciences, chemistry, biochemistry with a passion for applying molecular tools to real-world ecological challenges. Academic qualifications are considered alongside significant relevant non-academic experience. A master’s level qualification would also be advantageous. Equality, Diversity, and Inclusion: We value a diverse research environment and aim to be an inclusive university, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups. If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement. Enquiries and Applications: Formal applications should be submitted via the Red-ALERT CDT online application form prior to the closing date of this advert. Funding Notes Candidates may be considered for a NERC Red-ALERT studentship tenable for 3.5 years. Funding covers tuition fees, a stipend (£21,805 p/a in 2026/7) and access to a training support budget.

Position of DTU Tenure Track Assistant Professor in Microbial ecology and microbiome engineering

The Section for Microbial and Chemical Ecology at DTU Bioengineering is looking for an ambitious and creative researcher with a strong background in microbial and microbiome engineering for a tenure-track Assistant Professor position. The successful candidate will establish an independent, internationally competitive research program and contribute to teaching, supervision, and interdisciplinary collaboration in the area of microbial ecology and microbiome engineering. In this position, you will develop and strengthen departmental competencies in microbial and microbiome engineering for sustainable agriculture and other biological systems. Your research is expected to integrate fundamental microbiology, molecular microbiology and chemical ecology with applied microbial solutions addressing challenges in sustainable agriculture, biotechnology, and environmental management. Responsibilities You are expected to develop an independent, internationally visible research program that complements and expands the department’s strategic focus area microbial and microbiome engineering, while contributing actively to teaching and supervision. Your primary tasks and responsibilities will be to: Develop and lead an independent research program focused on microbial- and microbiome-based solutions for sustainable agriculture and other biological systems. Develop a research program spanning fundamental and applied aspects of microbial interactions, ecology, and function, with an emphasis on plant–microbe interactions. Publish research in high-quality, peer-reviewed international journals and disseminate results through conferences and scientific networks. Engage in interdisciplinary collaborations within the department and across institutional and external partners, including academia and industry Teach and contribute to courses at the BSc and MSc levels within microbiology, biotechnology, microbial ecology, and related areas. Supervise BSc and MSc student projects and serve as co-supervisor for PhD students. Actively seek and secure competitive external research funding from national and international funding bodies. Participate in departmental and university services, including committees and outreach activities. Qualifications A PhD in microbiology, biotechnology, microbial ecology, or a closely related area. A good publication record demonstrating research excellence in areas relevant to microbial and microbiome-based solutions, including microbial chemical ecology and molecular microbiology. A strong background in studies of the function and fate of microbial secondary metabolites in microbial communities. Experience in developing and applying experimental model systems such as synthetic communities to investigate complex microbial communities. Expertise in studying microbial interactions, integrating chemical, molecular, and community-level approaches to link mechanisms with ecological outcomes. Experience in translating fundamental research into microbial-based solutions, such as biological control, biofertilizers, or biostimulants. Documented experience in obtaining competitive external research funding as principal investigator or co-PI. Demonstrated ability to develop an independent research profile. Experience with interdisciplinary research and collaboration across scientific domains. Experience with teaching and supervision at the university level, or clear potential to develop high-quality teaching skills. Ability to supervise and mentor students in an inclusive and supportive research and learning environment. Strong written and oral communication skills in English. You must be responsible for the teaching of courses. DTU employs two working languages: Danish and English. You are expected to be fluent in at least one of these languages, and in time are expected to master both. As formal qualification you must hold a PhD degree (or equivalent). You will be assessed against the responsibilities and qualifications stated above and the following general criteria: Experience and quality of teaching Research experience Research vision and potential International impact and experience Societal impact Innovativeness, including commercialization and collaboration with industry Leadership, collaboration, and interdisciplinary skills Communication skills Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The starting date is according to mutual agreement. The position is a full-time position. The position is part of DTU’s Tenure Track program. Read more about the program and the recruitment process here. You can read more about career paths at DTU here. Further information  Further information may be obtained from Head of Section Professor Lone Gram (gram@bio.dtu.dk) You can read more about DTU Bioengineering at https://www.bioengineering.dtu.dk. If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure Your complete online application must be submitted no later than 13 April 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) Vision for teaching and research for the tenure track period CV including employment history, list of publications, H-index and ORCID (see http://orcid.org/) Teaching portfolio including documentation of teaching experience Academic Diplomas (MSc/PhD) Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus. Technology for people  DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive,

Position of PhD fellowship in computational analysis and modelling of protein interaction

The Amelie Stein group is looking for a PhD student in computational analysis and modelling of protein interaction. The PhD student will work together with other members in the Stein group as well as experimentalists in collaborating groups at UCPH and elsewhere, and other modellers in the Rosetta community. The PhD project aims to study the function of disordered proteins by combining coarse-grained molecular dynamics simulations, machine learning and bioinformatics. The start date is expected to be 15 July 2026, or as soon as possible thereafter. Details about the project, what we are looking for and how to apply can be found below. The project The PhD position is part of the Proteins in CONTEXT project where we aim to analyse limitations of current models for protein-protein and protein-ligand interactions, and use these insights to develop better models. The overall project combines data curation, benchmarking, and method development with classic and deep learning approaches. For background, see https://doi.org/10.48550/arXiv.2507.17446 and https://doi.org/10.1371/journal.pgen.1011681 as well as other publications from the group. Who are we looking for? We are seeking applicants with a Master’s degree in bioinformatics, (bio)chemistry, data science, or similar fields. The candidate should ideally have prior research experience (for example through an MSc project) within one or more of these areas: Structural modelling of protein interactions and complexes with tools like AlphaFold, Boltz1/2, Rosetta Development or application of of machine learning or classical models for protein modelling Analysis, interpretation and visualisation of medium- to large-scale sets of biological data The candidate should have a strong quantitative background. Our group and research- and what do we offer? The Stein group studies consequences of mutations on proteins and their interactions. This PhD project is fully computational, but the group also has scientists in the wet lab and collaborates with more, leading to close integration and insights into the data generation processes.  The PhD student will work in the group of Amelie Stein, located at the Department of Biology in central Copenhagen. The group is also part of an interdisciplinary and collaborative research environment at the Section for Computational and RNA Biology, and you will have the chance to interact with scientists across disciplines. The group is highly international, and a good level of spoken and written English is required. We offer a dynamic and international research environment. Current members of the research group come from a broad range of scientific and personal backgrounds, and we value openness, collaborations, and interdisciplinary work. We are strong proponents of open science. Inquiries about the position can be made to Associate Professor Amelie Stein, who will be the principal supervisor, at amelie.stein@bio.ku.dk. Note that all applications must be made via the online system as described below. The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background. The PhD programme Qualifications needed for the regular programme To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. bioinformatics or (bio)chemistry. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database. Terms of employment in the regular programme Employment as a PhD fellow is full time and for a maximum of 3 years. Employment is conditional upon your successful enrolment as a PhD student at the PhD School at SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant. Terms of appointment and payment according to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure. Responsibilities and tasks Carry through an independent research project under supervision Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE Participate in active research environments, including a stay at another research institution, preferably abroad Teaching and knowledge dissemination activities Write scientific papers Write and defend a PhD thesis on the basis of your project We are looking for the following qualifications: Professional qualifications relevant to the PhD project Relevant publications Relevant work experience Other relevant professional activities Good English language skills *************************************************************************** Application and Assessment Procedure Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below. Please include: Curriculum vitae (max 2. pages) including information about your education, relevant experience, language skills and other skills relevant for the position A cover letter (max 1. page) motivating why you are interested in this position and why you would be a good fit Original diplomas for Bachelor and Master and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. List of publications including preprints (if relevant). Do not attach the actual publications. Application deadline: The deadline for applications is 12 April 2026 23:59 GMT +2. We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. The further process After the deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified whether you will be passed for assessment. The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/. Questions For specific information about the PhD fellowship, please contact the principal supervisor Amelie Stein amelie.stein@bio.ku.dk General information about PhD study at the Faculty of

Position of PhD fellowship in Avian Influenza Pathology

We are offering a PhD fellowship in Avian Influenza in wildlife animals commencing 1 June 2026 or after agreement. Our group and research The DK-VET Veterinary Pathology Service (Patologivagten) is part of the Section for Parasitology and Pathobiology at the University of Copenhagen. The service contributes to national surveillance of diseases in wild mammals and birds, including monitoring of highly pathogenic avian influenza (HPAI) in avian and mammalian wildlife. Project description The purpose of the PhD project is to achieve more knowledge of interspecies and intraspecies transmission of high pathogenic avian influenza virus. The aims are to investigate spread of high pathogenic influenza virus among birds and mammals using both molecular biological and serological data. Determine cellular receptors present in target species, where in the cells the virus is located and identify species dependent differences in disease development and receptor expression. Techniques employed will include gross pathology, histopathology, immunohistopathology, as well as molecular biological and serological methods. Principal supervisor is associate professor Anne Sofie Hammer, Section for Parasitology and Pathobiology, E-mail: hammer@sund.ku.dk, Direct Phone: +45 23807692. Start: 1 June 2026 or after agreement Duration: 3 years Job description Your key tasks as a PhD student at SUND are: Carrying through an independent research project under supervision. Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points. Participating in active research environments including a stay at another research team. Obtaining experience with teaching or other types of dissemination related to your PhD project Disseminating your knowledge. Writing a PhD thesis on the grounds of your project Furthermore, the PhD student will contribute to other activities within the DK-VET Veterinary Pathology Service (Patologivagten), primarily tasks related to the project, including activities associated with avian influenza surveillance and research. Key criteria for the assessment of applicants You have an EU recognized education as a veterinarian (DVM). A Danish authorization number. Essential experience and skills included in the assessment of applicants: You have an active interest in gross pathology and histopathology. You have proficient communication skills and ability to work in teams  You have excellent English and Danish skills, written and spoken You have very good interpersonal skills and a high level of adaptability and flexibility You are thriving in a highly dynamic and busy workplace, with ability to work independently and systematically Experience with notifiable diseases would be beneficial, ideally including influenza. Place of employment The place of employment is at Section for Parasitology and Pathobiology, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences at the University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories, necropsy facilities, and a histopathology laboratory Terms of employment The position is covered by the Memorandum on Job Structure for Academic Staff. Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. The employment as PhD fellow is full time and for 3 years. It is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant. The PhD study must be completed in accordance with The Ministerial Order on the PhD program (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Questions For specific information about the PhD fellowship, please contact the principal supervisor Anne Sofie Hammer. General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/ Application procedure Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format: 1. Motivated letter of application (max. one page) 2. CV incl. education, experience, language skills and other skills relevant for the position 3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science 4. Publication list (if possible) The application, in English, must be submitted electronically by clicking APPLY NOW below. Application deadline: Sunday 12 April 2026, 23.59pm CET We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. The further process After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You find information about the recruitment process at: https://employment.ku.dk/faculty/recruitment-process/ The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities. Interviews are expected to be held in week 17/2026. The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background. Apply Now

Position of PhD fellow in the Tissue Architecture Lab at the NNF Center of Stem Cell Medicine (reNEW), Department of Biomedical Sciences

A PhD fellowship is available in the group of Mariaceleste Aragona at the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW) at the Department of Biomedical Sciences (BMI), Faculty of Health & Medical Sciences at the University of Copenhagen, commencing as soon as possible. Information on the department can be found at: https://bmi.ku.dk/english/about_department/ Information on the Aragona lab can be found at: https://renew.ku.dk/research/aragona-group/ Our group and research The team studies the molecular mechanisms that dictate stem cell identity and govern stem cell fate in regenerating adult epithelia. The group aims to understand how different cell types coordinate their decisions to build tissues with specialized structure and function, with the long-term goal of developing replacement organs for regenerative therapies. This research project will involve the development of standardized methods aimed at high-content drug screening and the study of the molecular mechanisms of tissue regeneration. Job description: We are seeking an enthusiastic PhD candidate with a strong background in stem cell biology and tissue culture expertise. The candidate will define protocol for the stem cell self-renewal maintenance, expansion and differentiation of in vitro epithelial culture in 2D and 3D from tissue-specific human stem cells to generate in vitro models of the adult bladder urothelium and develop functional drug screening approaches.  Collaboration with researchers within the group and the center, as well as external collaborators, will also be essential to drive the project forward effectively. The candidate is expected to integrate into and adhere to the group’s daily operational routines, including shared responsibilities, scheduling practices, and collaborative workflows. Key Responsibilities: Carrying through an independent research project under supervision with the goal of developing high-content screening approaches to study epithelia regeneration. Collaborate on complementary projects involving multi-omics investigation of tissue regeneration in the bladder urothelium. Completing PhD courses or other equivalent education. Participating in active research environments including a stay at another research team. Obtaining experience with teaching or other types of dissemination related to your PhD project. Teaching and disseminating your knowledge. Writing a PhD thesis on the grounds of your project. Qualifications: Candidates must hold a M.Sc. in Biotechnology or related field in life science. Essential: Documented hands-on experience with cell culture, differentiation of epithelial cells and barrier functions assays. Essential: Candidates must have extensive experience in 2D and 3D culture of epithelial cells and organoids, and a strong background in cell imaging. Essential: Documented hands-on experience in histological practices for analysis of protein expression across tissues. Essential: Previous experience in flow cytometry and image-based sorting. Desirable: Previous experience in the development of screening approaches. Excellent English communication skills, written and spoken, are prerequisite for the successful candidate. A solution-oriented, organizational and positive mindset is required. The ability to work in a highly collaborative environment both independently and as part of the team is essential. Place of employment The place of employment is at the Novo Nordisk Foundation Center for Stem Cell Medicine, Department of Biomedical Sciences, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment within a collegial atmosphere emphasizing academic excellence and responsibility. Our research facilities include modern laboratories and access to state-of-the-art facilities and instruments for flow cytometry, imaging, next-generation sequencing and cell engineering. Terms of employment The average weekly working hours are 37 hours per week. The position is a fixed-term position limited to a period of 3 years. The start date is as soon as possible. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 31,200 DKK/Roughly 4,170 EUR (November 2025 level) plus pension. The allowance will be agreed with the relevant union. The application must include: Motivation letter (it should describe your long-term research vision, the reason for applying to be part of our team and why you think you are the right candidate to fill this position). Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills for the position. List of two references (full address, incl. email and phone number). List of publications. A certified/signed copy of the Master of Science certificate. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database/?set_language=en. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science Questions For specific information about the PhD fellowship, please contact the principal supervisor, Associate Professor Mariaceleste Aragona mariaceleste.aragona@sund.ku.dk How to apply Your application must be submitted electronically by clicking ‘Apply now’ below. The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background. We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. Assessment procedure After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk    The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities. Application deadline: 14 April 2026, 23.59pm CET Apply Now

Position of PhD fellowship in Molecular Microbiology

Department of Plant and Environmental Sciences, Section for Microbial Ecology and Biotechnology, invites applicants for a PhD fellowship in molecular microbiology for bioremediation of PFAS. The project is part of the research project “Solving Microbial Degradation of PFAS”, which is financed by a Sapere Aude starting grant awarded to Tenure Track Assistant Prof. Tue Kjærgaard Nielsen by the Independent Research Fund Denmark (DFF). Start date is (expected to be) 1 July 2026 or as soon as possible thereafter. The project The PhD project focuses on microbial degradation of PFAS (“forever chemicals”) and aims to identify and overcome the biological barriers that limit sustainable PFAS bioremediation. PFAS are highly persistent environmental pollutants with significant risks to human health and ecosystems, and effective biological remediation strategies are currently lacking. The PhD candidate will investigate fluoride toxicity as a key bottleneck in PFAS biodegradation and develop novel approaches to enhance microbial tolerance and degradation capacity. The project combines environmental microbiology, molecular genetics, plasmid biology, and synthetic biology, and includes both laboratory‑based and soil‑based experiments. Key tasks include: Screening and characterization of PFAS‑degrading soil bacteria Enhancing fluoride tolerance in environmental bacteria using plasmid‑mediated gene transfer Genome sequencing and bioinformatic analysis of PFAS‑degrading strains Identification and analysis of PFAS degradation products using metabolomic approaches Development of synthetic biology strategies to enable PFAS degradation in complex soil microbial communities The PhD project is embedded in a larger interdisciplinary research program and will interact closely with postdoctoral projects in machine learning‑based enzyme discovery and environmental microbiome analysis. The position includes international research stays at leading laboratories in plasmid biology and synthetic biology. The project will provide the PhD student with strong training in environmental biotechnology, microbial genomics, and applied bioremediation, and addresses a pressing global environmental challenge with clear societal impact. Who are we looking for? We are looking for a highly motivated and curious candidate with a strong interest in environmental microbiology and biotechnology, and the ambition to work on a societally important environmental problem. The successful applicant should have: A Master’s degree (or equivalent) in microbiology, molecular biology, biotechnology, environmental science, or a related field Solid theoretical and practical experience within microbiology and/or molecular biology Experience with, or strong interest in, genetic methods, microbial cultivation, and laboratory work An interest in environmental pollution, biodegradation, and applied environmental research Experience with one or more of the following will be considered an advantage: Environmental microbiology and soil‑based experiments Microbial genomics, genome sequencing, and/or bioinformatic analyses Plasmid biology, conjugation, or synthetic biology Metabolomics or analytical methods related to xenobiotic degradation The candidate should be independent, well‑organized, and collaborative, with good analytical skills and the ability to work both independently and as part of an interdisciplinary research team. Good communication skills in spoken and written English are required. Our group and research- and what do we offer? You will be part of Tenure Track Assistant Prof. Tue Kjærgaard Nielsen’s newly formed and growing research group at the Section for Microbial Ecology and Biotechnology, Department of Plant and Environmental Sciences, University of Copenhagen. We are located in Copenhagen (Frederiksberg C). The group consists of approximately 10 people, including postdocs and thesis students. We apply molecular techniques and bioinformatics to study PFAS in the context of microbiology, stress responses, and ultimately bioremediation. There is focus on collaboration, synergy between projects, and a good and fun work environment. The Section for Microbial Ecology and Biotechnology comprises 60+ people with a diverse international background. Our research facilities include modern laboratories with in-house access to all necessary molecular equipment, including Illumina and Nanopore sequencing. We maintain our own servers and GPU-based workstations for in-house data analyses. Principal supervisor is Prof. Lars Hestbjerg Hansen, Department of Plant and Environmental Sciences, lhha@plen.ku.dk, Direct Phone: +45 28752053. Co-supervisor is Tenure-Track Assistant Professor, Tue Kjærgaard Nielsen, Department of Plant and Environmental Sciences, tkn@plen.ku.dk, direct phone: +45 35324188 The PhD programme A three year full-time study within the framework of the regular PhD programme (5+3 scheme), if you already have an education equivalent to a relevant Danish master’s degree.   Qualifications needed for the regular programme To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. [relevant educations]. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database. Terms of employment in the regular programme Employment as PhD fellow is full time and for maximum 3 years. Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of Science, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant. Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure. Responsibilities and tasks Complete and pass the MSc education in accordance with the curriculum of the MSc programme (ONLY when you are attending the integrated MSc and PhD programme) Carry through an independent research project under supervision Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE Participate in active research environments, including a stay at another research institution, preferably abroad Teaching and knowledge dissemination activities Write scientific papers aimed at high-impact journals Write and defend a PhD thesis on the basis of your project We are looking for the following qualifications: Professional qualifications relevant to the PhD project Relevant publications Relevant work experience Other relevant professional activities Curious mind-set with a strong interest in molecular microbiology and bioremediation Good language skills Application and Assessment Procedure Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below. Please include: Motivated letter of application (max. one page) Your motivation for applying for the specific PhD project Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position Original diplomas for Bachelor or Master and transcript of records in the original

Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia

Details The brain’s complexity has long been framed through the lens of neurons, yet another class of cells – astrocytes – quietly shapes the very circuits that underlie thought, memory, and disease. Despite comprising up to 40% of brain cells and being recognized since the earliest anatomical studies, astrocytes remained understudied for decades due to the technical challenges of probing their function. This gap is now closing. Advances in optical and genetic tools have opened a new frontier in neuroscience, revealing astrocytes as dynamic regulators of neural activity rather than passive support cells. The Khakh Laboratory has spent nearly 20 years developing methods to understand how astrocytes influence neuronal circuits and behavior. Now relocating from UCLA to the UK Dementia Research Institute (UK DRI) at Cardiff, the lab is launching an ambitious new research programme focused on uncovering how astrocytes contribute to brain function and, critically, to the development and progression of dementia. This move represents more than a change in geography – it marks the beginning of a new phase of discovery within one of the UK’s most vibrant and collaborative neuroscience environments. The lab’s long-standing record of innovation, continuous competitive funding, and high-quality publications provides a strong foundation for tackling pressing questions in neurodegeneration. A PhD student joining this programme will enter a deeply immersive and supportive training environment. The lab will combine molecular genetics, advanced imaging, electrophysiology, and translational neuroscience to interrogate astrocyte biology across multiple systems, from in vivo mouse models to human stem cell-derived astrocytes. This integrative approach allows trainees to develop a broad and versatile technical skillset while addressing mechanistic questions at the cutting edge of the field. The PhD project will explore how astrocytes shape neural circuit dynamics and drive pathological processes in dementia, with the goal of identifying new therapeutic strategies. Training in the Khakh Laboratory extends beyond experimental work. Students are mentored in data analysis, scientific writing, and presentation, preparing them for leadership roles in academia and beyond. The lab’s track record has been solid: all trainees who pursued academic careers have successfully secured faculty positions. This success reflects not only rigorous scientific training but also a culture that values curiosity, independence, and collaboration. The group itself is internationally diverse, bringing together talented scientists with varied perspectives united by a shared commitment to discovery. Importantly, the lab maintains a hands-on ethos. With active experimental engagement from Khakh and a collaborative atmosphere, students benefit from close mentorship and direct involvement in shaping their research projects. This creates an environment where ideas move quickly from concept to experiment, fostering both creativity and scientific rigor. For a prospective PhD student, this is an opportunity to join a leading lab at a pivotal moment – both in its relocation and in the broader changes within neuroscience. By contributing to a deeper understanding of astrocytes, students will help understand brain function and open new avenues for treating dementia and related disorders. Funding Notes This is a fully funded PhD project. Please contact Baljit Khakh with initial inquiries and kindly include a full CV with the names of two referees. References BS Khakh (2025) On astrocyte-neuron interactions: broad insights from the striatum. Neuron, 113, 3079-107. L. Wu, V. Pandey, VH. Casha, Z. Qu, Y. Jami-Alahmadi, V. Gradinaru, JA. Wohlschlegel & BS Khakh (2025) The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions. Neuron 113: 2599-2620. M. Ollivier, JS. Soto, KE. Linker, SL. Moye, Y. Jami-Alahmadi, AE. Jones, AS. Divakaruni, K. Kawaguchi, JA. Wohlschlegel & BS Khakh (2024) Crym-positive striatal astrocytes gate perseverative behavior. Nature (Article), 627: 358-366. JS. Soto, Y. Jami-Alahmadi, J. Chacon, SL. Moye, B. Diaz-Castro, JA. Wohlschlegel & BS. Khakh (2023) Astrocyte and neuron subproteomes and obsessive-compulsive disorder mechanisms. Nature, 616: 764-773. Apply Now

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