Fixed-term

Description of the doctoral project We are looking for a highly motivated doctoral student to join our research group in de novo protein design. The position is funded by a Novo Nordisk Foundation Ascending Investigator grant and focuses on developing next-generation protein-based catalysts for sustainable chemical transformations. With increasing global demand for sustainable materials, chemicals, and food production, there is a pressing need for innovative catalytic solutions. This project aims to design enzymes that do not exist in nature, combining physics-informed design principles, AI-driven protein engineering, and synthetic biology. About the position As a doctoral student, you will work at the interface of computational and experimental protein science. Your research will include: – De novo protein and enzyme design using computational and AI-based methods – Experimental expression, purification, and characterization of designed proteins – Development of novel biocatalysts for sustainable chemistry, green organic chemistry and circular bioeconomy applications – Integration of protein design with synthetic biology approaches – Previous work in interdisciplinary research environments Personal qualities such as analytical thinking, independence, collaboration skills, and scientific curiosity will be given great importance. The designed biocatalysts and their reaction products will be analyzed using interdisciplinary biochemical and biophysical techniques. You will be part of an international and collaborative research environment, with close interactions with academic and industrial partners. Dissemination of results through publications, conferences, and presentations will be an integral part of the position. Requirements To meet the general entry requirements you must have: been awarded a second-cycle (Master’s) qualification; satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or acquired substantially equivalent knowledge in some other way in Sweden or abroad (Higher Education Ordinance 1993:100, Chapter 7, Section 39). Specific entry requirements for the third-cycle courses and study programme in [Chemistry]. To meet the specific entry requirements, you must have knowledge corresponding to at least 90 HEC in chemistry (general, analytical, inorganic and physical chemistry as well as biochemistry and organic chemistry). This must include a degree project, and subject-specific studies at the advanced level of at least 30 HEC. You must also meet the equivalent English language requirements as those necessary for the Swedish upper-secondary qualification Engelska B/6. Your profile We are looking for a candidate who is highly motivated, creative, and interested in interdisciplinary research at the interface of chemistry, biology, and data science. Ruired qualifications: – Master’s degree (or equivalent) in biochemistry, biotechnology, bioinformatics, chemical biology, or a related field – Strong proficiency in spoken and written English Meriting qualifications: – Experience in protein engineering, enzymology, or molecular biology – Experience with computational methods (e.g. de novo protein design, molecular modelling, machine learning, or bioinformatics) – Experience with biochemical or biophysical characterization techniques About us The Department of Molecular Sciences at SLU in Uppsala has approximately 110 employees and, together with two other departments, forms an inspiring research environment at the BioCenter located on the Ultuna campus in Uppsala. Here, you will find expertise in chemistry, biotechnology, microbiology, plant biology and food science, as well as advanced infrastructure including molecular biology platforms, NMR, and X-ray techniques. The research in the advertised position will be conducted within the Organic Chemistry division, led by Professor Per-Olof Syrén, Chair of Organic Chemistry. Read more about staff benefits and life as an SLU employee on https://www.slu.se/om-slu/jobba-pa-slu/ Read more about third-cycle courses and study programmes on www.slu.se/utbildning/program-kurser/forskarutbildning/. Form of employment Employment as a doctoral student (4-year programme) Location: Uppsala/Ultuna Scope: 100% Start date: Upon agreement Application and selection: Please submit your application using the link below. The deadline is 25 May 2026. Read more about the attachments that your application should include at https://www.slu.se/en/study/programmes-courses/doctoral-education/how-can-i-become-a-doctoral-student/application/ Selection among eligible applicants is based on the documents attached to the application, and is carried out with regard to the applicant’s ability to complete the programme within the allotted time. Academic union representatives: https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/ The Swedish University of Agricultural Sciences (SLU) has a key role in the development for sustainable life, based on science and education. Through our focus on the interaction between humans, animals and ecosystems and the responsible use of natural resources, we contribute to sustainable societal development and good living conditions on our planet. Our main campuses are located in Alnarp, Umeå and Uppsala, however, the university also operates at research stations, experimental forests and teaching sites throughout Sweden. SLU has around 4,000 employees, 6,000 students and doctoral students and a turnover of over SEK 4,5 billion. We are investing in attractive environments on all of our campuses. We strive to provide a work environment characterised by inclusivity and gender equality, where different experiences generate conversations between people and pave the way for science, creativity and development. Therefore, we welcome applications from people with diverse backgrounds and perspectives. Contact person Per-Olof Syrén Professor perolof.syren@slu.se Apply Now

Faculty of Natural Resources and Agricultural Sciences The Department of Crop Production Ecology SLU is a world-leading university in the fields of agriculture and forestry and is one of the leading centres in the Nordic region for ecological research. We offer a dynamic and distinguished research environment combined with modern infrastructure. This includes advanced crop production facilities, four field research stations, more than 60 long-term agricultural experiments, including a new large-scale landscape experiment. SLU’s broad expertise in research related to the use and management of land, forests, and water, together with cross-faculty initiatives, creates opportunities for interdisciplinary research. The Department of Crop Production Ecology is primarily based in Uppsala. The Department develops knowledge on cropping systems to meet demands for both quantity and quality of food, animal feed, and bio-based raw materials in a sustainable way in a changing world. The research focuses on challenges arising from increasing demand, climate change, environmental impacts, and biodiversity loss linked to agricultural and food systems. The department’s research and education address crop production ecology from the molecular level, via the plant, the field, and the farm, up to the landscape level. Activities are organised in four subject areas: cropping systems, crop production specialized in forage, plant ecology, and weed ecology. Research is often conducted in collaboration with other scientific disciplines and with external stakeholders to contribute to the development of more sustainable agricultural and food systems. This position is placed in a research group in Umeå that primarily conducts research on sustainable and competitive agricultural systems based on forage crops such as ley, pasture, and whole-crop cereals to secure access to environmentally friendly and sustainable food from ruminants. This includes agronomic research, agricultural systems assessment, and applied remote sensing. The group provides teaching at both undergraduate and advanced levels, mainly within the agronomy- soil & plant programme, and is also active in courses for professionals. Together with a research group from the Department of Applied Animal Science and Welfare, the research group forms an inspiring and interdisciplinary research environment at the joint campus of SLU and Umeå University. The two departments work with a holistic perspective on sustainable agriculture that includes farm animals and crops, as well as their management. The research will form an important part of SLU’s node for knowledge development on food production and food security in northern Sweden, which is under construction. Read more about our activities and infrastructure here Read more about our benefits and what it is like to work at SLU here Subject area The subject encompasses crop production science with focus on forage-based agricultural systems including perennial grasslands. Duties The candidate should within the subject area develop and lead internationally successful research develop, lead and participate in teaching at first, second and third cycle level supervise doctoral students collaborate with other SLU research teams in order to strengthen interdisciplinary activities at the university develop and maintain national and international networks with academia, relevant public authorities, industry, organisations and society at large apply for external research funding contribute to the strategic development of the department, faculty and SLU communicate research findings and other relevant information to society at large perform administrative duties within the department, faculty and university. Swedish and English are used in parallel at the department. The holder of the position should be able to perform the majority of their tasks in English. However, as a public authority, the university has Swedish as its main language according to the requirements of the Language Act and the holder of the position must be able to use Swedish as their working language within four years of beginning the position. The department will provide support with language learning. Eligibility The applicant must meet the following qualification requirements: PhD or equivalent academic qualifications research expertise in the subject area teaching expertise and ability to integrate research and a scientific approach into teaching good knowledge of English. Assessment criteria In the assessment criteria for employment, the primary consideration should be the level of skill required for eligibility for the position. Assessment of the eligible applicant’s suitability for the employment will primarily be based on: completed and ongoing research in the subject area ability to independently initiate and conduct successful/outstanding research ability to obtain external research funding in competition ability of planning, implementation and examination, as well as evaluation of own teaching supervision and examination of doctoral students ability to integrate research and a scientific approach in teaching pedagogic vision and reflection. Furthermore, the assessment will consider the applicant’s expertise in: developing and leading activities and staff within academia collaborating with relevant stakeholders and society communicating research findings and development. As much attention must be given to the assessment of teaching expertise as to the assessment of research expertise. The position will be offered to the eligible candidate who, following a qualitative comprehensive assessment is deemed to have the best qualifications set to conduct and develop the duties in question, and contribute to the positive development of the organisation. Additional information * Swedish “universitetslektor”, a tenured position approximately equivalent to senior lecturer (UK) or associate professor (US). The applicant who is offered this employment at SLU will be employed as senior lecturer. This position offers the vibrant research climate at SLU. The benefits of the position include Swedish family health care provisions, parenting support including generous paid leave of absence policies that allow both parents to care for newborns and toddlers. Additionally Sweden has a well-established pre-school structure as well as an educational system that provides no-cost education through university studies. Find out more facts and stories about Sweden at www.sweden.se Located in the greater Stockholm region, the city of Uppsala has a rich history and culture, and is a true academic and cultural hub. Find out more about moving, living and working here at https://internationalhub.uppsala.se/ Application deadline: 2026-06-30 Place of work: Umeå Scope: 100 % Form of Employment: Permanent employment. Starting date: By agreement. Application: For the guidance of your application, there is SLU’s appointment procedure for teachers at SLU and General assessment criteria for

Details To apply, please click institution website. This is a fantastic opportunity to become involved and learn from several research and innovation projects within the Office for Rare Conditions (ORC) Registries Programme that include global rare disease registries such as SDMRegistries.org and GloBE-Reg which have a focus on rare endocrine conditions. The programme has a thriving research community locally which includes clinical scientists, data scientists, postgraduate research students and project managers. The studentship will support in-depth analysis of real-world clinical data within the registries as well as provide training and exposure to data management, database development, data governance and research ethics. Studies that the studentship will focus on relate to care quality improvement or assessment of the safety and effectiveness of new therapies. The successful candidate will also be expected to contribute to the formulation of new research ideas and submission of research publications. In addition to usual academic supervision, opportunities will also be provided to interact at a global level with several stakeholders including clinicians, scientists, patients and industry. Applicants will be expected to travel internationally to attend conferences and support for such events will be available. Funding Notes The funding will include an annual stipend of £21,480 for 2026 entry, with fees at the standard home rate for up to 3 years, with an additional training grant of up to £3,000 per year. Apply Now

About the role The Department of Cardiovascular Sciences at the University of Leicester are seeking a Research Associate to join them on a fixed term basis to lead a study aiming to improve the provision of healthcare for people with peripheral artery diseases globally. About you You will hold a PhD (or equivalent professional qualification and experience) in a relevant discipline and have a developing track record of contributions to peer-reviewed publications or equivalent outputs. You will bring expertise in vascular research, including the recruitment and delivery of studies involving people with abdominal aortic aneurysm and peripheral arterial disease, and experience of recruiting patients into NIHR-funded research. You will have a strong understanding of cardiovascular risk management in vascular populations and prior experience working clinically within, or closely with, the NHS. You will demonstrate strong analytical and problem-solving skills, excellent written and verbal communication, and the ability to convey complex information clearly. A collaborative team member, you will also be able to work independently while contributing to multidisciplinary cardiovascular research programmes. You will show commitment to continuous professional development and to supporting learning and development within the wider research team. Additional information Enquiries are welcome and should be made to  as875@leicester.ac.uk (Professor Athanasios Thanos Saratzis) and/or tmw24@leicester.ac.uk (Associate Professor Tom Withers) As part of the University’s ongoing commitment to professional development, this role will also be considered on a seconded basis for existing staff members. Please ensure this is discussed with your line manager prior to applying. More information regarding secondments can be found here   The University of Leicester has been changing the world, and changing people’s lives, for 100 years. When you join us, you’ll become part of a community of Citizens of Change, which includes not only our staff and our current students but also thousands of Leicester graduates around the world. As a diverse and forward-thinking employer, we embed the principles of equity, diversity and inclusion into everything we do. That includes not just our core missions of teaching and research, but also our support for staff, students and our local community through our values of Inspiring, Impactful and Inclusive through our values of Inspiring, Impactful and Inclusive. We’re committed to the wellbeing of all our staff and to the sustainability of our environment, on our campus and beyond. We offer a competitive salary package, excellent pension scheme and a generous annual leave allowance, along with opportunities to develop your career in a supportive and collaborative environment.

Overview Open to applicants eligible for UK/Home Tuition Fees only Supervisors: Professor James Burton jb343@leicester.ac.uk Dr Daniel March Dr Katherine Hull Project Description: People with chronic kidney disease (CKD) have a high symptom burden, with many reporting at least six, and some up to 20 different symptoms. Symptoms are often extremely debilitating, they negatively impact quality of life, and are associated with low treatment adherence, and mortality. Despite this, symptom recognition and management in CKD currently remains suboptimal (Zhu et al., 2023). Further to this, there appears a discordance between the prevalence of symptoms that are reported by people living with CKD, and the number that are estimated by healthcare professionals. The reasons for this discordance are multifactorial, although within clinical practice the assessment of symptoms such as CKD-aP are not routinely collected, which may play a role. Taken together, the result of this is that many people living with CKD are not offered treatment for these symptoms. One way in which symptom management may be improved for people living with CKD is through the regular reporting of symptoms; it has been previously recommended that this should be incorporated into usual clinical care (Davison et al., 2015). A method through which patient symptom burden can be captured is through the use of patient reported outcome measures (PROMS). PROMS are tools that use “any report of the status of a patient’s health condition that comes directly from the patient without interpretation by anyone else”. They are the outcomes that are the most important to patients and their families. However, within CKD care PROMS are not currently used, with several barriers limiting their implementation into healthcare systems. These include the patient and staff acceptance of PROMS, and the lack of integration into normal clinical workflow (Al Sayah et al., 2021). Therefore, there is a need to investigate current barriers to the regular use of PROMS, and investigate ways in which they can be implemented within clinical care. In order to inform the work of the Guideline Groups, the candidate for this project will conduct two independent systematic reviews to understand (based on the latest available evidence) the most effective treatments for CKD-aP and fatigue in individuals with CKD. In addition, subsequent qualitative analysis of interviews and focus groups involving people with CKD and health-care professionals (to be convened by the candidate) will provide an understanding whether the routine use of PROMs is feasible and desirable within the current NHS and UK Renal Registry framework. Using PDSA methodology, we will then evaluate a structured approach to the use of PROMs (delivery, data collection, clinical utility, implementation) through the Leicester Renal Network. This will provide an understanding of the both the feasibility of such a project (to inform scalability) and clinical efficacy. Finally, we will then undertake a national survey (using Delphi methodology) to understand both current practice in symptom management in those with end-stage kidney disease and to create a national consensus document on the use of PROMs in clinical practice. Please refer to the application advice below before submitting your online application. References: Al Sayah F, Jin X, Johnson JA. (2021). Selection of patient-reported outcome measures (PROMs) for use in health systems, Journal of Patient Reported Outcomes, 5(Suppl 2), 99 Davison SN, Levin A, Moss AH, Jha V, Brown EA, Brennan F, Murtagh FE, Naicker S, Germain MJ, O-Donoghue DJ, Morton RL, Obrador GT. (2015). Executive summary of the KDIGO Controversies Conference on Supportive Care in Chronic Kidney Disease: developing a roadmap to improve quality care, Kidney international, 88(3), 447-59 Zhu L, Li XL, Shi R , Wang DG. (2023). Dialysis vintage is associated with a high prevalence and severity of unpleasant symptoms in patients on hemodialysis, Renal Failure, 45(1); 2201361