Fixed-term

Description of the project A motivated postdoctoral researcher is sought to work on the molecular mechanisms underlying amyloid formation from the protein transthyretin. Transthyretin normally functions as a transporter protein of thyroxine and retinol-binding protein (RBP) in the serum and cerebrospinal fluid. However the folded protein is prone to instability and the formation of amyloid fibrils in tissues such as the heart and nervous system, invariably with fatal consequences. The project will focus on probing the molecular factors underlying this instability (see for example https://www.nature.com/articles/s41467-019-08609-z/), and in understanding the pathway that link the functional and pathological forms of the protein. Techniques involved will include X-ray and neutron crystallography, small-angle scattering (SAXS & SANS), and cryo-EM. The work will involve the study of wild-type TTR (which is intrinsically amyloidogenic) and also a range of other mutants that are typically associated with early onset amyloidosis in various tissues. The work may involve comparative studies with amyloid material derived fromex vivosources. Description of the workplace The Molecular Biophysics group is in the Department of Experimental Medical Science within Lund University Faculty of Medicine, and is led by Professor Trevor Forsyth. The group uses biophysical techniques to study biomolecular systems in crystals, solutions and partially ordered systems. Particular use is made of X-ray and neutron diffraction, cryo-EM, and a wide range of other biophysical techniques. The group is located in close proximity to the MAX-IV and ESS facilities in Lund which accommodates state-of-the-art facilities for synchrotron and neutron beam instrumentation as well as for cryo-EM. The group also makes extensive use of the ESRF and ILL X-ray/neutron sources in Grenoble, France, and at DESY in Hamburg, Germany. The project will have good access to state-of-the-art facilities within the medical, natural science and engineering faculties. Professor Forsyth leads the LINXS advanced study institute at the Science Village (https://www.linxs.se/) located between MAX IV & ESS and there is good access to a wide range of highly interdisciplinary science in life sciences, soft matter, and hard matter. Work duties and responsibilities You will need to be a proficient and independent worker with competence in protein expression, purification, crystallization, and biophysical characterization (purity, yield, stability) prior to neutron and X-ray scattering/diffraction experiments. You will also need to be competent with crystallographic diffraction data collection, data processing, solving & refining crystal structures using standard software.  The work may require travel to institutes including ILL in France, DESY in Hamburg, and other centres as needed for the project.  It may also require participation in national and international workshops/conferences. Description of the AMBER project context This post-doctoral position is part of the EU cofund research project AMBER, Advanced Multiscale Biological imaging using European Research infrastructures, will address scientific and sectoral gaps in biological imaging ranging from molecular, through cellular, to tissue, organ and organism levels of organisation, and is coordinated by LINXS Institute of advanced Neutron and X-ray Science. AMBER is funded by the EU Marie Skłodowska-Curie (MSCA) COFUND scheme. Around 15 postdocs will be recruited in the fifth call 2025, with each fellowship lasting 36 months. AMBER has six core partners: Lund University/MAX IV, Sweden, the European Spallation Source (ESS), Sweden, the European Molecular Biology Laboratory (EMBL), Institut Laue-Langevin (ILL), France, the International Institute of Molecular Mechanisms and Machines, (IMOL), Poland, and the Leicester Institute of Structural and Chemical Biology, United Kingdom. Your work may include clinical and biomedical projects. It may also include technique development work aimed at combining imaging techniques and data analysis to provide a more integrated picture of life processes in the context of health and disease. To be a postdoc fellow at the AMBER programme you will get unprecedented medical, biological, and methodological capabilities, with a profound potential impact for Europe’s next generation of research and researchers. When you have completed the AMBER programme you will be extraordinarily well equipped to further your career in academia, at infrastructures, in the health and MedTech sectors, and beyond. For more information about the total announced post-doctoral positions within in the AMBER co-fund project please visit https://www.euraxess.se/jobs/392999 The interviews will start in April/May 2026. For more information about AMBER, application and evaluation process etc please visit: ambercofund.eu Qualifications Minimum requirements are: Candidate needs to have a maximum 8 years after a doctoral degree (PhD), as required by the project Grant Agreement signed with the European Commission, At least one original publication in a peer-reviewed journal, A background in the relevant methods, A complete application package submitted through the AMBER portal (including CV and detailed research plan), and finally, Strict compliance with the MSCA mobility rule that the researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the host organisation’scountry for more than twelve months in the three years immediately prior to the call deadline. Each project will have additional specific requirements that candidates have to fulfill, be sure to check what these are before you apply. Undergraduate degrees in physical sciences, biological sciences or other relevant field. PhD or equivalent foreign degree within physical sciences, molecular biology, biochemistry, structural biology or a related subject. The PhD must be completed no later than the time the employment decision is made, Competence in protein expression and purification Competence in X-ray and/or neutron diffraction (eg crystallography, small-angle scattering) and associated data analysis. Ability to develop and conduct good quality research. Motivation and ability to work independently and as part of a team Proficiency in spoken and written English Personal skills are of importance. It is crucial that you are structured in your work and can work independently and have good social skills. The assessment of applicants will be based primarily on their scientific merit and potential as researchers. Particular emphasis will be placed on scientific ability within the subject area. We offer Lund University is a governmental authority, which means you get special benefits, generous holidays and a favorable occupational pension. We also have a flexible time agreement that creates good conditions for a balance between work and leisure. Read more on the university’s website about being

JOB DESCRIPTION The RNA Precision Medicine Center, Section of Translational Biology, at the Department of Biochemistry and Molecular Biology, the University of Southern Denmark, invites applications for a PhD student position within the field of pre-mRNA splicing and disease. The position is to be filled from 1 April 2026. The candidate will be part of a dynamic research group, which focus on generating a better understanding of all aspects of RNA biology in human disease and how to translate this into precision medicine. The present project is focused on pre-mRNA splicing regulatory mechanisms and how inherited mutations can cause aberrant splicing and human disease. Identification and characterization of splicing regulatory motifs and regulatory RNA binding proteins important for metabolic- cancerous- and neurodegenerative diseases. In the project, patient cells, model- and reporter-minigenes, gene editing and animal models, as well as in vitro RNA binding techniques and bioinformatics will be used to explore changes in mRNA splicing and to identify and characterize the involved cis- and trans-factors. The project has a special emphasis on correction of disease associated splicing and on identification and characterization of methods for up- and down-regulation of gene-expression employing splice switching oligonucleotides and RNA binding small molecule drugs. The project will generate basic knowledge on RNA-centered molecular mechanisms, the molecular pathology of aberrant splicing and it aims at translating this into new precision RNA medicine. Applications are sought from candidates with a master’s degree in molecular biology, biochemistry, cell biology, medicine or a related field and documented experience in molecular and cellular biology. Specifically, experimental expertise in RNA biology, including working with antisense oligonucleotides and RNA binding small molecule drugs for modulation of splicing, as well as hands-on experience with Next Generation Sequencing technologies and bioinformatics is preferable. Applicants should have demonstrated scientific productivity, good inter-personal and communication skills, good written and spoken English skills and be able to conduct independent and creative research. The Department of Biochemistry and Molecular Biology offers a strong, international and competitive research environment within the fields of RNA biology, molecular genetics and cell biology, protein chemistry and mass spectrometry, molecular microbiology and biophysics. For further information about the position please contact Professor Brage Storstein Andresen, PhD, FRCPath, e-mail: bragea@bmb.sdu.dk, phone: +45 6550 2413. Application, salary etc.   Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. Further information about the PhD programme at the Faculty of Science can be found at the University’s website. The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary (only available in Danish) and taxation. The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order). Further information about the PhD-study can be found at the University’s website. The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background. Application must be in English and made in the form of a Declaration of Interest including the following: A letter stating your specific interest, motivation, and qualifications for the project in question (max. two pages). Detailed CV, including personal contact information and date entries Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades. The names and complete contact details (phone numbers and e-mail) of at least two referees details for at least 2 referees who can vouch for your skills. Incomplete applications and applications received after the deadline will neither be considered nor evaluated. Apply Now

Your Responsibilities Activities for the implementation of the development agreement to be concluded with objectives in research, teaching, and administration Strengthening the work area of “Oncological Biophysics” through independent research on the molecular mechanisms of the interaction of antitumor agents with complex tumor models Collaboration with established research groups at the University of Graz, especially with regard to the application on 2D and 3D tumor models to reduce animal testing Participation in the application for and collaboration in competitively awarded research projects Coordination of the platform for “Alternative Tumor and Blood-Brain Barrier Model Systems and Development of Medical Agents” with focus on 2-dimensional and 3-dimensional tumor models and cytotoxicity studies as key technology in the field of biophysics Tumor models to reduce animal testing Independent development and establishment of methods according to the requirements in the work area Independent teaching of courses in molecular biology/biophysics/biochemistry (bachelor’s, master’s, and teacher training); (co-)supervision of scientific work Collaboration in university self-administration Your Profile Completed doctoral/Ph.D. studies in (Bio-)Chemistry or Molecular Biology International publication activity (first author or corresponding author) in a current field of biophysics and biochemistry in the research area of lipid systems, membrane-active agents, antitumor therapy Practical knowledge of fundamental biophysical and biochemical methods Expertise in working with tumor cell systems and membrane-drug interactions Expertise in working with model systems, model organisms, and human cell cultures (tumor and non-tumor cell lines) Knowledge of specific methods for determining drug-membrane interactions Excellent knowledge of German and English at Level C1, including technical terminology Practical knowledge in drug screening (desirable) Experience in project collaboration and management (desirable) Experience in writing project proposals Independent and self-reliant working style Reliability Organizational and teamwork skills Application Documents The following documents are required for an application: Letter of motivation and academic CV We offer an annual gross salary of € 70,200.20 for a fulltime position. We Offer Meaning: We offer meaningful work for the world of tomorrow. Our internal continuing education program is as colorful as the university itself. Collaboration: With us, you’ll find interdisciplinary, cross-professional opportunities to work together. Benefits: Of course, there are all the usual benefits, from A  “access to healthcare services” to Z “Zero emission goal”. Diversity: Besides our various scientific fields and their related issues, we offer a working environment in which diversity and inclusion are lived. Flexibility: We demonstrate flexibility not only with the various working time models but also through the offers for the compatibility of family and career. Contact Assoz. Prof. Dr. Dagmar Zweytick I dagmar.zweytick@uni-graz.at Institute Website Apply Now

Do you want to be a part of a collaborative effort, partly funded by the Sino-Danish Center, to study non-canonical activities of immunoglobulins? And do you see yourself as a teamplayer who is strong in collaboration? Do you see it as a unique opportunity to spend 9 months of the PhD in China? If yes, we look forward to reading your application to our PhD Stipend. At the Faculty of Engineering and Science, Department of Chemistry and Bioscience, a Ph.D. stipend is available within the general study program. The Ph.D. stipend is open for appointment from 01.04.2026 or as soon as possible thereafter. The position is for 3 years, and the workplace will mainly be at the Department of Chemistry and Bioscience in Aalborg with extended periods, up to 9 months in total, at Institute of Biophysics, Chinese Academy of Science, Beijing, China. Your work tasks While immunoglobulins constitute an active player, in the body’s protection against disease, by binding to, and clearance of, antigens, viral and other pathogens; this PhD project will focus on studying potential other functions of immunoglobulins. More than 75 years ago Linus Pauling hypothesized that immunoglobulins could possess enzymatic activities. Although some studies have reported hydrolytic activities of immunoglobulins isolated from patients suffering from a diverse array of diseases, no clear understanding of the importance of these activities is currently available. This PhD project aims to contribute to a better understanding of non-canonical functions of immunoglobulins and the role played in disease. Your competencies A master’s degree in biotechnology, molecular medicine, molecular biology, biochemistry or immunology, or a closely related field is an advantage. Excellent oral and written English language skills are a requirement. As the candidate will spend 9 months at Institute of Biophysics, CAS, Beijing, the applicant must be interested in working on a collaborative project, involving two different cultures. Also, as the applicant must be interested in working in an interdisciplinary research environment. Qualification requirements PhD stipends are allocated to individuals who hold a Master’s degree. PhD stipends are normally for a period of 3 years. It is a prerequisite for allocation of the stipend that the candidate will be enrolled as a PhD student at the Doctoral School of Engineering and Science in accordance with the regulations of Ministerial Order No. 1124 of September 19, 2025 on the PhD Programme at the Universities and Certain Higher Artistic Educational Institutions. According to the Ministerial Order, the progress of the PhD student shall be assessed at regular points in time. As part of the PhD study, you are among other things required to complete PhD courses corresponding to 30 ECTS, gain experience with teaching or other forms of knowledge dissemination and complete an external research stay outside of Aalborg University, preferably 3-6 months at a foreign research institution. In addition, the candidate can be enrolled as a PhD student at the University of Chinese Academy of Sciences, thus obtaining a double degree (https://sdc.university/research/phd/). Who we are At the Department of Chemistry and Bioscience (BIO), our high-level research spans from basic to applied within both natural sciences and engineering. With approx. 150 employees, 75 PhD students, and 775 bachelor and master’s students at our campuses in Aalborg (main campus) and Esbjerg, we are a vital research and educational institution when it comes to creating new basic knowledge as well as contributing to solving the world’s challenges within biology, chemistry, biotechnology, bioengineering, environmental science, and chemical engineering. We continuously improve our department as an attractive place of work and study. We offer flexible hours, social activities throughout the year both at the department level and in each Section. We are inclusive and have respect for individuals, communities, and cultures. Our work culture is founded on openness, curiosity, transparency, and involvement. Come join us! Read more about the department here;Welcome to the Department of Chemistry and Bioscience – en.bio.aau.dk – Aalborg University. The Sino-Danish Center (SDC) is a partnership between all eight Danish universities, the Chinese Academy of Sciences (CAS) and the University of Chinese Academy of Sciences (UCAS). SDC’s activities include Danish-Chinese research collaboration within six selected focus areas, eight affiliated Master’s programmes with an annual intake of approximately 150 master’s students and training of a large number of PhD students. The overall objective is to promote and strengthen collaboration between Danish and Chinese learning environments and increase mobility of students and researchers between Denmark and China. The current PhD project will be conducted as a collaboration with Institute of Biophysics, CAS, Beijing (http://english.ibp.cas.cn/). How to apply Your application must include the following: Application, stating reasons for applying and qualifications in relation to the position Curriculum Vitae (CV) Diplomas (bachelor’s and master’s degree diploma, including grades) Other relevant documents The application must be submitted via Aalborg University’s recruitment system, which can be accessed under the job advertisement on Aalborg University’s website. Aalborg University wants to reflect the surrounding society and has diversity as a core value. Therefore, everyone, regardless of personal background and orientation, is encouraged to apply for the position. Do you have any questions? If you have any questions about the position, you are more than welcome to contact us. You will find contact persons at the bottom of the jobpost. Further information Read more about our recruitment processhere. The assessment of candidates for the position will be carried out by qualified experts. Shortlisting will be applied. This means that after the application deadline, the head of the department, with the assistance of the hiring committee, will select the applicants to be assessed. All applicants will be informed whether they have been shortlisted for assessment or not. The hiring process at Aalborg University may include a risk assessment as a tool to identify potential risks associated with new hires, ensuring the safety, compliance, and integrity of the workplace. Read more aboutThe Doctoral School of Engineering and Science Salary and terms of employment The employment is in accordance with theMinisterial Order on the Appointment of Academic Staff at Universities (the Appointment Order)and theMinisterial

The Natural History Museum Denmark (NHMD) at the University of Copenhagen is offering a fully funded PhD scholarship in insect biodiversity, focusing on poorly known groups of insects with many unknown species (dark taxa) using large-scale DNA barcoding and citizen science. Expected start date: 1 May 2026 – or as soon as possible thereafter. The Project The PhD fellowship is part of an externally funded nation-wide research and outreach project “Unknown Insects – Mass Experiment 2026”, which combines large-scale citizen science and outreach with modern DNA-based biodiversity research. The project will engage thousands of primary school and high school students throughout Denmark in the collecting, sorting and documentation of insects from their local natural areas. The collected samples will be analyzed at the Natural History Museum Denmark using megabarcoding, a highly efficient DNA barcoding method that enables rapid and cost-effective processing of tens of thousands of individual insects. The DNA barcodes will be linked to image material, environmental data and physical voucher specimens, which will be preserved in the museum’s scientific collections. The PhD project will utilize the data to investigate key research questions, for example: species richness, composition and geographical distribution of Denmark’s neglected insect fauna the relationship between known and previously unknown species across habitats taxonomy and systematics of dark taxa, including species delimitation, identification and classification of poorly known insect groups with updates to the Danish and Global fauna comparison of morphological speciation and DNA-based identification the importance of natural history collections and citizen science in modern biomonitoring The project is expected to result in several peer-reviewed scientific publications and contribute to the long-term building of biodiversity data and collections at the museum. Principal supervisor is Anders P. Tøttrup Professor and Deputy Museum Director of Research Natural History Museum Denmark, University of Copenhagen aptottrup@snm.ku.dk (+45) 51 82 69 88 About the Natural History Museum Denmark The Natural History Museum Denmark is the Danish national museum for nature. We work to empower citizens to connect with nature with the aim to create positive change for people and planet. We want to inspire, engage, and enable people to enjoy, understand, and care for the diversity of the natural world. The impact of climate change and anthropogenic forces on biodiversity has reached a critical point. We firmly believe that natural history museums can and should play a key role towards a more sustainable relationship with nature. We are currently building a new Danish national museum for nature. One big museum site, in the Botanical Garden, in the center of Copenhagen, will host state-of-the-art laboratories, outstanding research collections, new public galleries, and combined facilities for programming, education, and citizen science. It is an ambition for the museum to enhance natural history and inspire curiosity, knowledge, and empowerment for the future. The Natural History Museum consists of the national Botanical Garden, and the new museum site with public galleries, offices, laboratories, and collection space. The Botanical Garden was founded in 1600. The collections date back to Ole Worm’s Cabinet of Curiosities from around 1620. With 14 million preserved specimens and 8,000 different species in the Botanical Garden, it is the largest museum collection in Denmark. It covers our planetary history with botanical, zoological, and geological specimens from all over the world. The Natural History Museum Denmark is part of the Faculty of Science at the University of Copenhagen. The University of Copenhagen was founded in 1479 and is the largest in Denmark. Read more about the museum at http://www.snm.ku.dk/english/. Supervision and Research Environment The PhD fellow will be associated with the Natural History Museum Denmark and be part of an active research environment with expertise in entomology, taxonomy, DNA barcoding and citizen science. The project is anchored in the museum’s zoological collections and molecular laboratories. As part of the PhD program, a research stay at a foreign institution is expected. The project will be part of an already established international collaboration with strong research environments within integrative taxonomy and DNA-based biodiversity research, including with NTNU University Museum (Norway). Who are we looking for? We are looking for someone with an interest in insect biodiversity, collection-based natural history research and citizen science, as well as a curiosity for working with unknown and overlooked species groups (dark taxa). Applicants must have a background in biology or related natural science subjects, equivalent to a Danish Master’s degree (MSc). The PhD project will include citizen-driven data collection and analysis of large biodiversity datasets. There is also the opportunity to work with unknown species in the form of species determination, taxonomy and systematics, as well as the use and development of new molecular methods and image recognition. The PhD project is closely linked to a nationwide citizen science initiative, and it is therefore crucial that the applicant has an interest in, and preferably experience with, communication and collaboration with non-professional target groups. The PhD fellow is expected to be able to communicate research processes and results to the general public and especially to children and young people, both orally and in writing. Terms of employment in the regular programme Employment as PhD fellow is full time and for maximum 3 years. Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure. The PhD fellow will be based at the Natural History Museum Denmark, Faculty of Science, University of Copenhagen, located in Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include a museomic laboratory and advanced microscope and imaging labs among other facilities, 14 million natural history specimens within geology, botany and zoology, and a botanical garden with scientific collections of living plants. The PhD programme A three year full-time study within the framework of the regular PhD programme (5+3 scheme), if you already have an education equivalent to a relevant Danish master’s degree. Qualifications needed for the regular programme To be eligible for the regular PhD programme,