Fixed-term

The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 68 research groups and 800 employees, the Department of Biomedicine is the largest department at the University. We are located in the heart of Basel at 6 different locations. Be part of our future!The Dixon Lab at University of Basel is seeking a highly motivated postdoctoral research fellow to study neuro-immune interactions in cancer. The role of intra-tumoral neurons is complex and still not fully understood. While some studies suggest they play a critical role in tumor progression and metastasis, others report that they may contribute to anti-tumor immunity. Our lab is dedicated to understanding the innervation landscape of peripheral tumors and its role in immuno-oncology.  Your position We are particularly interested in candidates who have experience in immunology and have previously worked on cellular and molecular networks underlying tissue health and disease. Our goal is to conduct impactful interdisciplinary research interfacing tumor biology, immunology, and neuroscience to investigate the role of neurons in regulating tumor immunity. Candidates will be expected to take the lead role in their projects, publish manuscripts as the first author, and present their projects and data at lab meetings, as well as international meetings. We are looking for someone who is excited to discover and answer questions related to neuro-immunology, and who demonstrates critical thinking, scientific rigor, and attention to detail. Your profile A Ph.D. in immunology, oncology, or a related field. Strong interest in immunology. Strong skills in conducting independent in-vivo studies, and knowledge of managing strains for independent projects, including genetically modified mouse models. Experience with spectral flow cytometry is essential. Experience with cell sorting, preparation of tissues for RNAseq and confocal microscopy analysis is highly desirable. Experience in cellular and molecular biology.  Strong organizational and analytical skills with the ability to work independently. Excellent written and oral communication skills. Commitment to teamwork and collaboration. We offer you We are seeking an individual excited to study neuroimmunology in cancer. The successful candidate would join a dynamic team of international researchers with an interest in collaborating and helping each other. Mentorship and career development are critical aspects of our overall mission. Abundant one-on-one time and the support required for successful completion of projects are the foremost priorities of the lab. Close collaboration with neighboring neuroscience, oncology, immunology, and cancer immunology labs ensures a large, dynamic, and vibrant scientific network. Additionally, mentorship on the transition into subsequent career stages, including establishing of independent research programs will be provided.  Application / ContactPlease use the link below to apply and submit the following documents: I. curriculum vitae II. brief summary of past accomplishments (max 2 pages) III. contact details for 3 individuals who can provide recommendation letters upon request. The position is available immediately and will remain open until filled by suitable candidate. Apply Now

The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need.With more than 70 research groups and over 800 employees, the Department of Biomedicine is the largest department at the University of Basel. We are located in the heart of Basel at several research sites. Be part of our future!The Bischofberger Lab investigates the cellular and circuit mechanisms underlying learning, memory, and cognitive plasticity in the hippocampus.Environmental enrichment and physical exercise induce complex interactions with environment and conspecifics and are promising interventions for memory deficits and dementia. However, the underlying cellular and molecular mechanisms are still poorly understood. Most importantly, the effects of environmental complexity on hippocampal coding and synaptic excitation–inhibition balance are unknown.In a new project funded by the Swiss National Science Foundation, we are using in-vivo calcium imaging in freely moving mice (miniscope imaging), together with optogenetics, chemogenetics, and in-vitro patch-clamp recordings to understand plasticity of cognition generated by environmental enrichment or, vice versa, by environmental deprivation. We focus on mechanisms underlying object discrimination, spatial navigation, social interactions, and social recognition memory.Initially, the project focuses on mechanisms involving dendritic inhibition via somatostatin interneurons (Schulz et al. 2018, Nat Commun. 9:3576; Schulz et al. 2019, J Neurosci. 39:5210–5221; Verdiyan et al. 2026, bioRxiv 10.64898/2026.03.31.715605) and will continue investigating the role of various other interneuron subtypes. Your position Participation in experimental neuroscience projects investigating hippocampal information processing and cognitive plasticity Performance of in-vivo calcium imaging experiments in freely moving mice Support and execution of stereotaxic surgeries and behavioural experiments Involvement in in-vitro patch-clamp recordings and data analysis Collaboration within an interdisciplinary research team Contribution to laboratory organization and scientific discussions Your profile Highly motivated applicant with experience in at least some of the following areas: mouse handling stereotaxic surgery in-vivo Ca2+-imaging (miniscope or 2-photon imaging) Python-based data analysis PhD in Neuroscience, Biology, Physics or a related discipline Strong interest in systems neuroscience and hippocampal circuit function  Independent, reliable, and team-oriented working style  Excellent communication skills in English We offer you We offer the opportunity to work in a dynamic and collaborative international research environment at the University of Basel. The successful candidate will receive training in cutting-edge neuroscience techniques and contribute to innovative research projects investigating hippocampal circuit function and cognition.The lab provides close mentorship, a supportive team atmosphere, and access to state-of-the-art research infrastructure. Collaboration with neighbouring neuroscience groups ensures a vibrant scientific network and stimulating interdisciplinary exchange.  Application / ContactPlease use the link below to apply and submit the following documents: I. curriculum vitae II. brief summary of past accomplishments (max 2 pages) III. contact details for 3 individuals who can provide recommendation letters upon request. 
The position is available immediately and will remain open until filled by suitable candidate. Apply Now

The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need.With more than 70 research groups and over 800 employees, the Department of Biomedicine is the largest department at the University of Basel. We are located in the heart of Basel at several research sites. Be part of our future! The Bischofberger Lab investigates the cellular and circuit mechanisms underlying learning, memory, and cognitive plasticity in the hippocampus.Environmental enrichment and physical exercise induce complex interactions with environment and conspecifics and are promising interventions for memory deficits and dementia. However, the underlying cellular and molecular mechanisms are still poorly understood. Most importantly, the effects of environmental complexity on hippocampal coding and synaptic excitation–inhibition balance are unknown.In a new project funded by the Swiss National Science Foundation, we are using in-vivo calcium imaging in freely moving mice (miniscope imaging), together with optogenetics, chemogenetics, and in-vitro patch-clamp recordings to understand plasticity of cognition generated by environmental enrichment or, vice versa, by environmental deprivation. We focus on mechanisms underlying object discrimination, spatial navigation, social interactions, and social recognition memory. Initially, the project focuses on mechanisms involving dendritic inhibition via somatostatin interneurons (Schulz et al. 2018, Nat Commun. 9:3576; Schulz et al. 2019, J Neurosci. 39:5210–5221; Verdiyan et al. 2026, bioRxiv 10.64898/2026.03.31.715605) and will continue investigating the role of various other interneuron subtypes. Your position Conduct a PhD project on hippocampal circuit plasticity and cognitive function Perform in-vivo calcium imaging experiments in freely moving mice Perform in-vitro patch-clamp recordings in acute brain slices Contribute to experimental design, data interpretation, and scientific publications Present results in lab meetings and international conferences Your profile Highly motivated candidate with a Master’s degree in Neuroscience, Biology or Physics Interested in learning both, in-vivo calcium imaging and in-vitro patch-clamp recordings Strong interest in systems neuroscience, neuronal circuits, and behaviour  Motivation to learn advanced neuroscience techniques Independent, reliable, and team-oriented working style  Strong organizational and analytical skills  Good written and oral communication skills in English We offer you We offer the opportunity to work in a dynamic and collaborative international research environment at the University of Basel. The successful candidate will receive training in cutting-edge neuroscience techniques and contribute to innovative research projects investigating hippocampal circuit function and cognition.The lab provides close mentorship, a supportive team atmosphere, and access to state-of-the-art research infrastructure. Collaboration with neighbouring neuroscience groups ensures a vibrant scientific network and stimulating interdisciplinary exchange.  ApplicationPlease use the link below to apply and submit the following documents: I. curriculum vitae II. brief summary of past accomplishments (max 2 pages) III. contact details for 3 individuals who can provide recommendation letters upon request. 
The position is available immediately and will remain open until filled by suitable candidate.  Apply Now

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease.We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.The Tumor Heterogeneity Metastasis and Resistance led by Prof. Mohamed Bentires-Alj, is looking for a Bioengineer and 3D culture expert. Join our community and help shape the future of biomedicine. We are seeking a highly motivated and innovative Bioengineer specialized in complex 3D culture systems to join our multidisciplinary team at the interface of clinical research, biomedical imaging and personalized oncology. This position offers the opportunity to contribute directly to translational science and personalized cancer treatment decisions. You will be embedded in a dynamic, interdisciplinary team including clinicians, cancer biologists, organoid and drug screening experts, bioinformaticians, and data scientists. We use state-of-the-art technologies such as image-based drug screening and imaging mass cytometry to inform clinical decision making for patients with advanced cancer. Your position Drive the development of organ-specific heterotypic 3D co-culture models using patient-derived tumor material, with iterative optimization of media compositions. Establish and scale miniaturized co-culture platforms in 384-well formats, enabling compatibility with automated high-throughput drug screening workflows. Design and execute robust comparative drug screening assays to evaluate therapeutic responses. Develop and apply automation workflows, including liquid handling technologies, to ensure reproducible and high-precision cell seeding. Work collaboratively with organoid specialists and data scientists in a highly interdisciplinary environment. Ensure rigorous documentation of experimental procedures and support the translation of methods toward clinically relevant, scalable high-throughput applications. Your profile PhD degree or equivalent expertise in biomedical/tissue engineering, biology, biotechnology, or a related field. Hands-on experience with complex 3D culture systems and their application in cancer research. Solid knowledge of cancer biology and tumor microenvironment dynamics. Practical expertise in imaging techniques and immunofluorescence. Strong organizational skills, pragmatic and clear mindset. Highly motivated, creative, team-oriented, and collaborative; Excellent oral and written English communication skills. We offer you A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities and in the heart of multicultural city of Basel. Your position will be embedded in the lab of Prof. Bentires-Alj but you will work in a consortium working on different types of cancer. Lab website: https://bentireslab.org/ Application / ContactPlease upload your CV, a summary of your research experience and interests, techniques that you are competent in, and the contact details of three referees including your current PI at:https://biped.dbm.unibas.ch/apply/bioengineer-and-3d-culture-expert-start-july-september-2026 Application deadline: Applications will be reviewed as they arrive. Contact: thmrjobapplication-dbm@unibas.ch   Apply Now

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease. We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research. The Tumor Heterogeneity Metastasis and Resistance led by Prof. Mohamed Bentires-Alj, is looking for a Data scientis in Oncology. Join our community and help shape the future of biomedicine. We are seeking a highly motivated Data Scientist to join our multidisciplinary team at the interface of clinical research, biomedical imaging and personalized oncology. This position offers the opportunity to contribute directly to translational science and personalized cancer treatment decisions. You will be embedded in a dynamic, interdisciplinary team combining clinicians, cancer biologists, organoid and image mass cytometry experts, bioinformaticians, and data scientists. We use state-of-the-art technologies such as image-based drug screening and imaging mass cytometry to inform clinical decision making for patients with advanced cancer. Your position The successful candidate will play a central role in analyzing complex, image-based datasets to generate clinically actionable insights. Your main responsibilities include: Process and analyze image-based drug screening and imaging mass cytometry (IMC) data. Engineer software solutions and manage the clinical data pipeline. Apply advanced image analysis techniques, including segmentation, feature extraction, and quantification of cellular phenotypes and spatial patterns. Develop and implement AI/ML models (e.g., deep learning approaches for segmentation, classification, or predictive modeling) tailored to biomedical imaging data. Integrate multi-modal data to identify biomarkers and inform treatment decisions in a translational context. Create and maintain custom scripts and pipelines to automate and streamline data processing workflows. Summarize key findings in concise, actionable reports for clinical collaborators. Collaborate closely with, biologists, and other data experts to interpret results and refine analyses. Ensure rigorous data quality control, reproducibility, and critical evaluation of results. Your profile PhD degree or equivalent expertise in data science, bioinformatics, computational biology, computer science, physics, engineering, or a related quantitative discipline. Strong programming skills in R and Python (preferred) with experience in data analysis and scripting. Solid knowledge of statistical methods and data visualization. Experience working with high-performance computing environments and Git for collaborative development. Experience deploying AI/ML models in production or research environments, and with deep learning frameworks such as PyTorch or TensorFlow. Strong team spirit, excellent communication skills (English), and ability to work in a multidisciplinary environment. High motivation, critical and meticulous approach to data handling and interpretation. Genuine interest in translational science and bridging computational methods with clinical applications. Background in cancer biology or oncology research is a plus. Experience in software development is a plus. Experience with analysis of sequencing data is a plus. Experience with job scheduler (e.g., SLURM) is a plus. We offer you A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities and in the heart of multicultural city of Basel. Your position will be embedded in the lab of Prof. Bentires-Alj but you will work in a consortium working on different types of cancer. Lab website: https://bentireslab.org/ Application / ContactPlease upload your CV, a summary of your research experience and interests, techniques that you are competent in, and the contact details of three referees including your current PI at:https://biped.dbm.unibas.ch/apply/data-scientist-oncology-start-july-september-2026 Application deadline: Applications will be reviewed as they arrive.Contact: thmrjobapplication-dbm@unibas.ch Apply Now