Research specialist position in immunology and drug development

Do you want to contribute to top-quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching in immunology, infection biology, cell biology and cancer. Our keywords are multidisciplinary, bridging, national and international collaborations.

Subject description

Lisa Westerberg’s research group is looking for a person with a well-documented research and teaching profile in drug development and immunology.

Your role

We are looking for an independent and highly motivated research specialist with extensive expertise in immunology and drug development, especially against immunodeficiency diseases with a special focus on megakaryocyte biology and platelets. The selected candidate will lead projects related to platelet function and its interaction with immunodeficiency disease and run drug screening campaigns on a laboratory scale using CRISPR-Cas9-modified cell line models. The studies will be performed with human samples and murine models. The research specialist is expected to design and lead his/her own projects, contribute to other projects in collaboration both in the laboratory and with external collaborators, and mentor students.

Eligibility requirements

For employment as a research specialist at Karolinska Institutet, the eligibility requirements stated in Guidelines for employment other than teaching positions at Karolinska Institutet are applied in relation to the established employment profile.

Eligible to be employed as a research specialist are those who have demonstrated scientific proficiency and have completed a doctoral degree or have a foreign degree that is deemed equivalent to a Swedish doctoral degree and have documented research work after a public defense.

In addition to the above requirements for the role:

• Extensive experience in drug screening and drug reuse
• Extensive knowledge of flow cytometry with high-throughput and multiparametric methods
• Extensive experience working with human and murine model systems in immunology and blood cells
• Experience in generating new mouse models through gene editing
• Extensive experience in supervising students
• Ability to work in a team
• Excellent communication and organizational skills
• PhD in immunology, cell and molecular biology or other relevant field

Qualifications for the role:

• Proven expertise in flow cytometry analysis and cell sorting
• Proficiency in using ImageJ, Cell Profiler or similar for image segmentation and quantification
• LAS – Function A (Experimental Animal Science)
• Knowledge in primary cell culture, such as human blood cells and in mu cells from various organs, ability to perform flow cytometry analysis and cell sorting, as well as expertise in confocal/super-resolution microscopy and perform downstream analysis with appropriate image analysis software for segmentation and quantification
• Documented knowledge in drug screening campaigns using both microscopy and flow cytometry-based methods
• Higher pedagogical education

Assessment criteria

It is particularly meritorious that the applicant has demonstrated:

• Research experience from a research group other than where the doctoral education was carried out
• Presentations and scientific assignments at international congresses
• Development of one’s own research profile within one’s subject area
• Plan for future research based on current science
• National and international research collaborations towards innovation

It is desirable that the applicant has demonstrated:

• Original scientific work, its quality and quantity with special consideration after doctoral studies
• Review articles and other scientific publications

It is based on a comprehensive assessment of the applicants’ qualifications and skills that Karolinska Institutet assesses which of the applicants has the best potential to contribute to the positive development of the business.

What do we offer?

A creative and inspiring environment filled with competence and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Here we conduct successful medical research and have the largest range of medical education in Sweden. At KI you will meet researchers with different research areas who work together. It is this cross-border collaboration that contributes to KI’s world-leading position in research. Several of the people you meet in healthcare are educated at KI. A close relationship with healthcare is important for creating education and research of the highest quality. As a university, Karolinska Institutet is also a government agency. This means that as an employee you receive good benefits through our collective agreement.

Location: Solna

ki.se/en/mtc/lisa-westerberg-group 

Application

We prefer that your application is written in English, but it is also possible to apply in Swedish. The application must include the following documents: Certificate of doctoral degree, CV, qualifications and description of planned research presented in accordance with Karolinska Institutet’s qualifications portfolio.

Applications must be made via the Varbi recruitment system.

In the case of permanent employment, Karolinska Institutet applies a 6-month probationary period.