Website Vienna BioCenter Core Facilities
Your mission
As (Senior) Technician Functional Assays* at Bio-LogX you will join our research team in our lab in Vienna and help us bring next generation drugs from the bench into the clinic.
Your main responsibilities will be.
Your main responsibilities will be.
- Culture and maintain solid tumor cell lines (e.g., breast, pancreatic, lung, and melanoma models).
- Isolate, expand, and cryopreserve primary immune cells, including PBMCs, T cells, and NK cells.
- Plan and perform T- and NK-cell-mediated cytotoxicity assays to assess the efficacy of protein-based modalities.
- Conduct functional characterization studies to elucidate mechanisms of action, including immune activation marker analysis by flow cytometry and cytokine profiling using ELISA and MSD/Luminex platforms.
- Analyze and interpret experimental data using tools such as Excel and GraphPad Prism, contributing to internal reports and scientific presentations.
- Maintain accurate and up-to-date standard operating procedures, laboratory notebooks, and equipment calibration and maintenance records.
- Oversee reagent inventory and support general laboratory operations and maintenance.
Your profile
What you have to offer.
- Degree (B.Sc. / M.Sc.) or diploma in Immunology, Oncology, Molecular Biology, or a related field. Note: this position is designed for B.Sc./M.Sc. level.
- Must: 2-3 years of experience handling immune cells (T cells, NK cells, PBMCs).
- Experience with multicolor flow cytometry, including data analysis using FlowJo.
- Practical experience with T/NK-mediated cytotoxicity assays and ELISA-based assays.
- Experience in culturing solid tumour cell lines under appropriate conditions.
- Strong collaborative mindset and fluency in English.
- Strong candidates will also offer at least one of the following:
- Experience with multiplex cytokine assays (MSD/Luminex).
- Familiarity with statistical/data analysis tools such as GraphPad Prism and SPSS.
- Knowledge of immuno-oncology drug development, including the tumour microenvironment and current therapeutic landscape.
Why us?
Benefits for you.
- Take responsibility for key research processes and assays in our lab.
- Be responsible for maintaining a high-performance lab including by developing standards and supporting the overall lab operations
- Become part of a fast-paced, multinational team developing new drugs for patient populations with high medical need.
- A competitive compensation package that reflects the qualifications and seniority of the candidate and may include further, e.g. performance-based, incentives. Due to legal requirements, we are required to state that the minimum salary for this job is a monthly salary of EUR 2.800,– gross, where candidates with extensive experience can expect to earn EUR 3.500,– gross or more.
About us
Bio-LogX, recently founded by BioNTech R&D Austria’s leadership team, is a VC-backed translation & innovation engine based at the Vienna Biocenter. We develop drug candidates from animal to clinical proof of concept – always with the ambition to transform the standard of care. We are agnostic about the therapeutic area but focus on protein modalities: antibodies, enzymes, fusions, engagers, degraders, agonists, antagonists.
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