Determining the efficacy of probiotic use across the female lifespan

Project overview

There is a distinct lack of female specific data related to numerous aspects of physiology across the lifecourse. Females undergo a number of specific transitions throughout their life (such as onset of menses and menopause) that are linked with varying degrees of symptoms. In order to build more targeted interventions for both health and diseases it is imperative we understand the roles of the female sex hormones.

This PhD will focus on the Gut brain immune axis and collectively assess the mechanisms by which probiotics may operate and alter aspects of physiology at key stages of the female lifespan. Optibac is the UK’s bestselling brand of probiotics with recent investment in development of female specific products. This PhD proposes to support the development of bespoke female products, providing more detailed mechanistic insight into the actions by which the probiotics may support female health across all stages of the lifecourse.

There will be a multi-disciplinary approach combining methods of neurophysiology, immunology and gut microbiome composition.

It is intended to conduct several human intervention studies throughout this program, therefore being able to interact and recruit relevant populations will be well received.

Please do reach out for more specific details on the project.

Supervisors

1) Dr Jessica Piasecki (Jessica.piasecki@ntu.ac.uk)

2) Dr Neil Williams (neil.williams@ntu.ac.uk)

3) Dr Ella Baker (ella.baker@wrenlabs.com)

4) Dr John Hough (john.hough@ntu.ac.uk)

Entry qualifications

Undergraduate degree completion in field of interest.

How to apply

Follow this link to apply, applications close Thursday 15 January 2026, to start project in April 2026.

Fees and funding

It is a fully match funded studentship, funded between NTU and Optibac Ltd. The Successful applicant will receive 3-year stipend and fees covered as part of the studentship as per the completed contract.

Guidance and support

Find out about our Doctoral School and research community.

Still need help?

Contact Dr Jessica Piasecki on:

• Email: Jessica.piasecki@ntu.ac.uk