Clinical Trials Monitor

About the role

We are looking for a Clinical Trials Monitor to join the UKCRC registered Imperial Clinical Trials Unit (ICTU) team, to be responsible for clinical trial monitoring activities for two innovative real-world data randomised controlled trials, including a CTIMP.

The COLLABORATE Trial is a UK‑wide adaptive study assessing the effectiveness and safety of commonly used enteral feeds in reducing necrotising enterocolitis, mortality and cognitive impairment in extremely preterm infants.

The PATH Trial will evaluate whether personalised antibiotic prescribing can improve survival in hospitalised sepsis patients while addressing antimicrobial resistance.

You will work closely with the Trial Managers, site teams, and clinical staff to ensure the trials are conducted in accordance with Good Clinical Practice (GCP) and regulatory requirements.

What you would be doing

You will be responsible for monitoring activities at investigator sites, including feasibility, initiation, enrolment and follow-up, close-out and archiving, with guidance from the Trial Managers.

You will:

• Conduct on-site and central monitoring to verify source data and ensure compliance.
• Perform Source Data Verification (SDV) and oversee site performance.
• Perform Site Initiation Visits (SIVs) and Close-Out Visits (COVs).
• Prepare monitoring reports and maintain regular site communication.
• Monitor Investigational Medicinal Product (IMP) accountability.
• Maintain the Trial Master File (TMF) and distribute Investigator Site Files (ISFs).

The role requires travel to investigator sites across the UK, with occasional overnight stays.

What we are looking for

• Science degree or equivalent.
• Monitoring experience, ideally for CTIMPs.
• Experience conducting SIVs, monitoring visits, COVs, and performing SDV.
• Knowledge of ICH-GCP and UK Clinical Trials regulations.
• Strong communication, organisational skills, and attention to detail.
• Willingness to travel and work flexibly.

What we can offer you

• An opportunity to develop your skills in clinical trials within novel therapeutic areas.
• Continue your career at a world-leading institution contributing to science for humanity.
• Sector-leading salary and remuneration (including 41 days’ annual leave and generous pension schemes).
• Flexible working from day one, generous family leave, on-site leisure facilities and cycle-to-work scheme.
• Interest-free season ticket loans.
• Diverse, inclusive and collaborative work culture with staff networks and wellbeing.

Further information

The Imperial Clinical Trials Unit (ICTU) is a UKCRC-registered unit committed to excellence in clinical trial design, conduct, and dissemination. We deliver health benefits through high-quality research in a dynamic and supportive environment.

Fixed-term, full-time for 18 months with potential to extend subject to funding.

If you require further details, please contact: Hanna Box – h.box@imperial.ac.uk.