PhD position – RNA Quality Control Lab

Your tasks

• Investigate how transcription elongation and termination failure generates immunogenic double-stranded RNA
• Build iPSC-based models using endogenous tagging and degron systems, and differentiate them into neural progenitors and neurons
• Generate and analyse your own data: nascent transcriptomics, RNA-seq, proteomics
• Design and interpret your own experiments
• Present at group meetings, institute seminars and international conferences, and write your work up for publication

Your profile

• Master’s degree (or equivalent) in biology, biochemistry, molecular medicine or a related field, completed by the start date
• Solid experimental foundation in molecular biology and mammalian cell culture
• You are feedback driven: you can sense one clear guidance cue to change how you work
• Motivated to work at the bench and at the terminal; prior coding experience is not required, we will teach it
• Good written and spoken English

Desirable qualifications

• Experience with iPSC culture, neural differentiation or CRISPR genome editing
• Experience with next-generation sequencing or its analysis
• Familiarity with R or Unix
• Background in transcription, RNA biology, innate immunity or the stress response
• Interest in helping set the direction of a group in its first year

This position provides the opportunity for you to build specialist knowledge whilst developing key professional experience, both of which will help you to make strides in your scientific career.

Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees at Federal Level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of receiving an allowance if the applicable conditions are met. The position has an (initial) fixed term of three years but may be extended under certain circumstances.

Benefits

International Staff Service

Support with the relocation and integration process in Germany

Scientific Resources

State-of-the-art infrastructure and Core Facilities

Recreation

30 days annual leave, flexi days, plus public holidays

Health Promotion

Sports, company doctor, mental health initiatives

Career counseling

Career Center for PhD candidates

Scientific Training

Helmholtz Munich Graduate School