Research assistant position in data-driven gene control for regenerative medicine

Do you want to contribute to improving people’s health?

In this new research group, we focus on using synthetic biology to solve important challenges in regenerative medicine. To this end, we develop molecular tools and computer algorithms to predict and control cell behaviors useful for tissue repair. Specifically, our goal is to combine genome editing tools (e.g. CRISPR) with predictive algorithms to enable data-driven, precision-guided engineering of cell identity and function, with a particular focus on stem cells.

We operate at the Department of Laboratory Medicine, which consists of seven departments with both research and teaching activities. The department conducts advanced research that includes both basic and applied research. All departments have close collaboration with clinics at Karolinska University Hospital. The Department of Biomolecular and Cellular Medicine (BCM) focuses on the use of cells, cell products and modified biomolecules as new therapeutic tools, as well as on identifying and studying suitable biomolecular and cellular targets for treatment and diagnostics. The department is also connected to the Karolinska ATMP Center.

We are now looking for two research assistants with a strong background and practical experience in CRISPR technology, molecular cloning and cell culture. Culturing of stem cells and/or immune cells, single-cell RNA sequencing and bioinformatic analyses are required.

Your role

We are looking for an ambitious and collaborative team player with a passion for pushing the boundaries of regenerative medicine by programming complex cell behaviors for next-generation cell therapies.

Your profile

We are looking for a candidate with a strong background in biomedicine and biotechnology, with experience in bioinformatics, who is passionate about taking on major challenges in regenerative medicine using synthetic biology.

The candidate must:

• Have a master’s degree in biotechnology, biomedicine or a related field.
• Demonstrate practical experience and proficiency in a range of laboratory techniques – specifically PCR, DNA/RNA extraction, molecular cloning, bacterial transformation, CRISPR, cell culture (stem cells and/or immune cells), transfection/transduction/nucleofection, flow cytometry, immunofluorescence.
• Demonstrate experience in working with gene regulatory networks and bioinformatic analysis.
• Fluent in English and self-motivated, meticulous and collaborative, with the ability to work independently. We are currently a small and dynamic group where members are expected to be responsible team players who help each other. Great emphasis will be placed on personal suitability and the ability to collaborate effectively in a team.

What do we offer?

A creative, international and inspiring environment filled with competence and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to drive the development of knowledge about life and work for better health for all. Here we conduct successful medical research and have the largest range of medical education in Sweden. As a university, Karolinska Institutet is a government agency. This means that you receive good benefits through our collective agreement. Employees at KI are also offered the opportunity for a flexible working method. This means that if the business you work in allows, you can work part of your working hours remotely. You are also allowed to exercise freely in our modern wellness facilities where trained staff are on site.  

Location: Flemingsberg

Application

KI applies individual and differentiated salary setting according to our collective agreements RALS and RALS-T. 

We prefer that your application is written in English and should include a CV and a cover letter.

Welcome to apply!

The application must be submitted through the recruitment system Varbi.

In the case of permanent employment, Karolinska Institutet applies a 6-month probationary period.